TTC or pregnancy on prednisolone or similar part 13

[VillageMum]

This is a positive thread for all those diagnosed with High or Very High NK Cells and looking to start TTC or already pregnant on Prednisolone and/or Intralipid treatment.

Newcomers very much welcome!

Well there's a mental image duggs!!;)

I do wonder why dr g didn't put oh on antibiotic again after sperm frag

What was his level Mel?

His dfi is 39.1 and hds 15.5, that was nearly a year ago and he's just been on proxeed ever since, it's making me wonder. We both went on antibiotics with Peny and I conceived twice last year x

We had antibiotics with penny back in feb 2013! He tested negative for mycoplasma and ureaplasma last oct when he had frag test done. I've emailed penny to ask her, maybe it's because he was negative x

Thanks duggs! Very helpful.
I suppose it does sound like a long time but main thing is u for there in the end and ur going to have a little baby yay!
Im waiting patiently 4 more days before I do a hpt. Time going slow!

Penys recommended he takes anti b again then retest- not sure hel go for that idea!

Good luck trying x

Hi all. I'm so sorry I haven't fed back even after all you kind responses which gave me reassurance. The lymphnodes went down. Started steroids post ov but didn't appear to ovulate this cycle so starting super ovulation next cycle :-(...

Anyway I want to also say sorry I keep joining when I have an issue...I've been reading back to earlier threads on this and the super ov one...duggs I've been reading your story...my heart goes out to you and of course everyone else who has been on this journey...and for you to have now made it the end..all my blessings that you have healthy delivery. You are the success story that we all are looking out for. And of course sue and free too.

I'm so sorry if I have left anyone out. I have read back so many messages and I have gotten a little lost...I'm blaming it on the drugs...

I'm a little worried about the super ov. I have to take the letrozole and then inject with Ovitrelle...not sure what I'm supposed to do with it because I received the Ovitrelle injection prescription today on the post because Louise forgot to give it me at my appt on Monday (didn't see Shehata).

Struggling with the preds. My mood swings have been bad and have been terribly low. And omg I am a raging insomniac ...but I guess all this is normal.

It worked for you ladies though so I guess I have to persevere through right?

Interested in the DNA frag test. Where did you get it done? Cost? Time taken start to finish?

Anyway all the best to everyone, and again I'm really sorry I haven't been in touch, for being a chronic lurker, forgetting to thanks everyone who shared kind reassuring words..
Xxxx

Hi rb30 I'm sorry your feeling low. It is hard. I'm worried I'm not ovulating either and don't want to go down the SO route-but like you said just have to preserve and keep going and use the others on here as our success stories to keep going. How do u know u didn't ovulate? And was this the first time? Oh have u had some struggles with getting preg up to now?
Im sorry I can't help with the injections etc but sure someone helpful will at some point
Look after urself, This is hard work at times

Ovitrelle is kept in the fridge. You take your letrozole (I'm on gonal f days 2-7) then I have a scan about day 12 then they suggest when to inject ovitrelle following your scan report. You inject in your tummy then Dtd following it for a couple of days.
The sperm frag I can't recall cost I think it took a couple of weeks for results.

Ovitrelle - easy as pie, IIRC it's a pen injection and really simple to do. Seriously don't worry about it :)

Thanks mel for the info. Am seeing Dr S on day 15 of cycle as have a long cycle.

trying I've been using cbfm to work out whether I ov and I appear not to have this cycle. I've had 4 mc', last one (mmc) was taken out 24/4/14 Then needed a d&c a month later because of retained preg, then Dr s did a hysterscopy in August and more preg tissue. So this cycle was my first ttc month since mc. I had been monitoring my ovulation in previous months and was ov around day 19. I'm on 33 day cycle. Frustrating the month I start ttc I don't ov! Got fed up of Dtd so stopped by day 19 too when I should've ov...I'm ranting sorry. It really is hard isn't it. So fed up of it all. I actually preferred not trying.

I think the ov may have stopped because I started taking this supplement called pregnitude (American). It has myo-inositol in it. It's supposed to regulate periods and ov especially if you have pcos (I do). So combined with the metformin I've been on for a couple of months I think I may have just pumped to many chemicals in to my body along with all the other I14 or so vitamins and supplements I'm taking.

Are you trying for your first 1? How long have you been trying? Are you with Dr S and are you on his preds programme? Did you have NK tests done?

rb30 as has been said above the ovitrelle injection just needs to be kept in the fridge, i keep it on the middle shelf towards the front. The injection itself is ok too, i hate needles and injections so the thought of injecting myself made me feel quite ill (i'm trying not to think about the intralipid drip as the thought of the canula makes me feel very ill!), the needle is really fine and you hardly can feel it. I just googles ovitrelle videos and watched a couple on you tube so i had a rough idea of what i was doing. I have given myself two injections now and am actually quite proud of myself! I have found that SO has made my cycle shorter - last month it was 28 days exactly and also i like to know that i have ovulated - it provides me with reassurance.

I'm trying for my first, I am under Dr S and have high NK cells so on his pred/intraplipid programme once I get pregnant.

I am no medical expert but i do somethimes think we are looking for answers that different supplements can provide the answer for, we pump our bodies with whatever we can get our hands on. I have stopped taking all supplements except the ones Dr S has prescribed.

Thanks sunnyday. Very interesting to know about the change in your cycle. What were you before? And when did you ov then compared to now? Have you had any side effects to the SO?

I'm on the same prog with dr S. I had to do humira shots which weren't nice. Realised doing them straight out the fridge was a bad idea because the cold liquid is so uncomfortable. For these Ovitrelle I'll make sure to leave them at room temp for a bit before injecting (or is that not advised)?

I agree with supplement approach. Are you just on omega 3, aspiring folic acid, multivitamin, and d3? I was taking coq10 before Dr S and he told me not to bother, but when I went to collect the letrozole on Monday Louise told me to carry on with the CoQ10. I've read in loads of sources that coq10 does help egg quality and sperm quality so hubby going on that too.

How have your partners been? Are they supportive and sympathetic of the stress of this? My dh doesn't seem to understand. Maybe my fault for expecting him to fully understand what An emotional roller coaster this is and he does make every appt with me, but whenever I just want to talk about it and cry (a side effect of the preds) he doesn't want to hear it. He'll just shut me down by saying relax don't worry about. That doesn't make me feel any better.

The trigger shit dictates when you ov - last month it was day 14, this month day 13. My cycle was generally 31 days and I'm not sure exactly when I ovulated but guess around day 17. Not had any sude effects with letrozole but get extreme thirst on the pred!

Yes I'm on pregnacare with omega 3, vit d and asprin. Not hears about CoQ10 before.

Dh is very supportive he wants it as much as I do. I really need to get my weight down but struggling!

that's nice about your dh. Dh wants it but he's very emotionless just by nature, so I'm really struggling to accept it from him at mo.

Sorry about the weight issue. Are you generally trying to eat better and exercise? Although I wasn't trying to lose weight, I was given for metformin which helped me shed pounds. Not that I encourage you to take that. Not sure if this is of any use to you, but short high intensity training is better than spending hours at the gym. Running at your fastest pace for 300 metres alternating with say 250m on the rowing machine will give you full body / cardio/resistance workout, with 3 sets each, that could be less than a 20minute workout. Otherwise I recommend jillian michaels 30day shred. I have seen loads of people lose inches by doing that. And it's healthy /low weight workout (20mins again). after last mmc I started training again doing hiiT (mixed with Shawn T insanity every so often) to get rid of mmc pregnancy weight very quick compared to previous times. Didn't keep it up. Will start training again start of next cycle.

A number of my friends struggled to get pregnant. They then went on some strict training regime for a few months and they all went on to have babies

Sunnyday good luck with this. Let me know how you get on.

Hi rb30. Yes trying for my first. Been trying for 18 months and had 3 miscarriages. Back on ttc and on cycle 3. Doing the whole prog plus acupuncture. My nk cells were normal but activity was high (just). That's the only issue found so far. Gosh sounds so hard having that tissue left and not being able to move on with things-it's very trying.tablers never work for me so I end up in a limbo of scans with tiny bits left being told it will come away and then needing a d and c. It really drags things out. If there's ever a next time straight to d and c for me. But I hope not.
Sorry about ur dh. Men deal with it very diff. My dh is actually a psychologist so quite in tune with his and my emotions. However sometimes he's a man! And it does upset me...have u got friends u can talk to?
Sunny day where in ur cycle are u?

Sunnday-do u have fitness ap? The only way I can loose weight is to track every single thing I eat and see it and count calories. It's tedious and hard coz I do like my food! But it works for me (have put on 3 pounds with my recent 2 week Holiday and very annoyed! ). Also ww worked for me coz someone weighs me and I feel to emb to have to lost! So I find that helpful too...tbh with miscarriages etc focussing on weight loss is so hard. I've just brought my bmi to 25 and am now stuck and need to try get things kick started again as I presume when I take daily pred at a bfp I will put on lots!

trying i'm on day 5 of the pred and day 17 of my cycle. Not finding the pred too bad again, have extreme thirst again like last month but apart from that can't complain too much!

Hi all - Duggs, also be great to hear about the sperm drag route.
Suemays- what is the good sperm/ egg theory - does this mean you think overactive immune systems are irrelevant or just that even when calmed down you can be unlucky anyway?
Is anyone on hydroxychloroquine? I'm between my 1st and 2nd cycle of steroids but taking hydroxy any have really dry eyelids and elbows and wondered if anyone else suffered this and had tips?
Good luck to all about to have babies and those looking to conceive and keep theirs too

Hey well.. Really freelance is the best advocate for the Dr S immune treatment as seemed to be exCr solution for her. Myself,
SueMays and others it wasn't so simple and tbh the super ovulation route didn't help me even after 8 months or so trying. Just hope you are like freelance and straightforward immunology is the issue.
If not don't give up as many of us just need to find the chromosonally good egg and sperm at the right time. Raised and hyper active NK cells seem to be indicative for most people and I have had tests that showed they were active and tests showing they were normal and I had as many mc on immune suppressing treatment as I did off it. The sperm dna fragmentation tests that are more popular in the US and with doctors like Dr gorgy and nudwuke address the man too. (Dr S may test now but he didn't a few yrs back). Sperm is refreshed every 90 days so strong anti biotics are needed in case of hidden infections etc and are a vital step in my opinion. Anyway.. See how things go. I got v excited about the super ovulation programme but it did raise my expectations and (reduced my bank balance) a lot which in retrospect dos nothing to help me, but once I saw Dr gorgy and got the sperm issue tested and sorted things became easier. Best of luck and let's hope you are all like freelance and just need a few steroids to pop for a few months - rather than years

Duggs - I have an (imaginary) alarm that goes off whenever your name comes up on MN as I am on tenterhooks for your news!

Duggs that's really useful info. I did consider gorgy..might need to go there for hubby. Dr S didn't suggest anything for dh but will ask him re dna frag test. I've also so heard getting men on to vitamin c, vitamin e xinc and coq10 could help so I bought a load of vits for him.
I'm sorry to hear the dr a programme didn't work. This pregnancy did you follow any of the protocols re preds etc? Or was it natural? Rooting for you to have a healthy delivery.

Trying sorry about your experience. Fingers and toes crossed for you. Where do you have Acupunture? I'm seeing mike Gorman in Solihull...

Oh and did a hpt yest. Didn't expect to be pregnant because I don't think I ov but was still disappointed! Roll on AF