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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

Eggcellent Egg Buddies! Come and join us if you're IVFing in August, September or October!

999 replies

nobeer · 24/08/2013 11:43

Share your experiences, worries, recipes, holiday recommendations. Swearing welcome.

OP posts:
Stillhopingstillhere · 12/09/2013 17:43

That's good to know!

Can you have a bad immediate reaction to these drugs does anyone know? It seemed the main risk was ohss but that isn't instantaneous. I am worried about being the only one here with ds and something happening. My parents are away at the same time although I probably wouldn't ask them anyway as they are really disapproving about the whole thing.

resipsa · 12/09/2013 18:24

Still the injections don't hurt, really. I hated needles and the one good thing so far to come from this IVF business is that they no longer bother me. You're in control, remember.

I did mine alone and couldn't have tolerated being watched. It's really not so bad. The problem is the resulting head fuck.,.

ThoughtfulOne · 12/09/2013 18:28

I want - I'm due to start injection on 28th I think. I'm on microgynon until then.

Lemon - I hope it went well today.

Welcome Dharma.

Waves to everyone else. I'm a bit useless at keeping up with everything.

I'm currently stressing and feeling ridiculously guilty about asking for time off work or even having ivf. It's so stupid but I can't help it. I feel like a work failure and a reproductive failure. It's so f'ing unfair!

I also enjoyed the conversation about failure pills. I stopped taking them after my second ectopic but am on them again now.

On a good note I had acu last night and had a point in my third eye which has done wonders for my frown lines! I'm so vain.

X

tametortie · 12/09/2013 19:30

Bonjour mon petit chien Smile

miss yes it was me that has the high NK cells. I took prednisolone throughout my last cycle. I had the test done in Siobhan Quenby's clinic at UHCW. Its very very simple- you book an appointment with her, have the test done and she e-mails you the results and prescribes steroids if needed. I would highly recommend her- she is a pet.

Do we have lots of excitement coming up?

I hope so- I'm bored rigid waiting to start. Hopefully though, I have had a 'proper' cycle this month as its now day 23 of my cycle and this time last month I was almost full flow.

I fell out with my best friend today too over something stupid so I now the Russians are ironing the flag....

IWantOneNow · 12/09/2013 20:06

The Russians are ironing the flag? Hope ur ok [tame] arguing with ur best friend is so sad Flowers.

BrookerC · 12/09/2013 21:57

Evening ladies!
Lots going on in here lately. I am a robot obvs -have religiously carried on with the pills despite everything! euro my nails are also the best they've ever been. Wish I could say the same about my skin...Hmm
drizzle good luck with your trigger tonight. Would love to hear what drugs / scans you've had in the run up (hoping to do FET if possible next time & I'm a nosey cow Wink)
nobeer is it your review tomorrow lovely? How are you feeling? x
tame how shit to have a falling out with your bf Sad
llw glad the little fuckers are under control Grin Hope those follies are growing nicely. Don't forget the update tomorrow x
Welcome dharma Smile
Hi to everyone else -sorry for lack of personals, I'm losing track! xx

WannabeMaryPoppins · 13/09/2013 07:00

Morning all,
nobeer good luck with your review today. Let us know how you got on
drizzle good luck!
llw let us know how your scan goes
miss enjoy camping. Hope you packed your wellies
life and fab when are your reviews? Aren't they soon?
Iwant Glad that AF has arrived. Exciting times ahead!
still I didn't have any side effects with the injections. Just go with your gut feeling
dhama hello! I was petrified of needles before this all started. To the point where I couldn't be in the same room as a syringe. But you do what you have to do and now I am fine still hate them though and actually feel very proud of myself Grin
to everyone else

AFM, well AF is on her way but hasn't arrived yet. Have been trying to work out when we could go for our next FET. As I have to miss a cycle it is going to be November at the earliest. But it looks like we may have to put it back another couple of months because we have booked a holiday in November and there is no way we are cancelling that and then there is a lot going on at work around the beginning of Dec with lots of travelling and flying. It is all so frustrating but I am trying to be patient and failing miserably

BrookerC · 13/09/2013 07:40

On the clinic advice theme, mine advised taking folic acid & vit D only. They also advise caffeine to be cut to 1 cup a day I asked my consultant directly about alcohol & his response was very clear - maximum of 5 units per week during stimming & nothing after ET. It makes a big difference for me to be able to have the odd glass of wine here & there.
I too had a needle phobia before IVF. The irony now is that now I actually quite enjoy doing it as it represents me doing something pro-active on the ttc front Hmm
miss enjoy the camping Smile
maryp I hear you on the waiting. A holiday sounds like just the ticket. Where are you off to? x

Badhairday76 · 13/09/2013 08:02

Hello everybody. Please forgive the lack of personals - I can't scroll up on my phone once I start typing to remind myself but am wishing good luck for all of you with scans, reviews etc today.

I sent my DP to the doctors to organise his blood tests prior to our Fertilty Clinic referral yesterday and feel a bit more proactive. It will be two weeks tomorrow since my tube and ectopic pregnancy removal and physically feel almost back to normal. It somehow feels wrong that I don't have more obvious gaping wounds from something so devastating. It will feel very odd this month not 'trying' to get pregnant through sex. I expect my partner will be secretly relieved because I was making him do it 10 days in a row every month. Good job he is a younger man!

I watched that Horizon programme last night that somebody reccommended (sorry, can't check who it was!) Intersting segment on IVF, I agree. Are there still that many medical staff in with you during egg collection? In my mind, I had thought there were only one or two medical staff. From what I've read, they 'sedate you', but don't give you the full General Anaesthetic - are you awake or just zonked out on morphine? I definitely want to be awake if possible. Have had too many GAs recently and it takes ages for me to recover from them. My throat and mouth have still got ulcers from the breathing tube being pulled out. Hope everybody has good days today. I am at home alone whilst my son is at nursery and I plan on a v lazy day...

Lifeasafish · 13/09/2013 08:46

Morning all!

badhair I think there were only 2 people in with me, and there were no mouth tubes involved. The tubes are painful enough without mouth uclers. I was dopey afterwards though. Apparently I told MRfish the tube was fine (which it was) but I still cannot remember going home. He reckons I did what we call the dope fiend lean ( from 'the corner', ace film re heroin abuse in Baltimore, the fiends defy gravity when high).

I understand what you mean re scars, I feel that there should be something to say my embie was here. I've debated a tattoo, just a tiny unseen one but then it seems crass to me and for me. (I don't judge others on that sort of thing at all btw, I've seen beautiful memorials expressed in tattoos).

I felt the same as brooker re needles.

tame sorry about your friend, do you want to discuss it? Losing a friend is like a bereavement, in fact I had a dream about an ex-best friend last night even though its been 3 years.

Why is someone triggering with FET? Sorry, I cannot remember who. And wannabe I'm sorry re your delay, we had a delay due to a holiday before our first cycle and actually it worked well as I was nice and calm having spent a week discussing with mr fish and exploring feelings etc.

I didn't drink at all from first bureslin until confirmed miscarriage, but I struggled with caffeine. I allowed myself 1 tea or coffee each morning. Then bought decaff tea in the end, which I don't like but I drink a minimum of 4 cups a day regardless of weather.

My review is on Tuesday and I'll post the questions just now (this is long!)

Lifeasafish · 13/09/2013 09:10

Embryo/miscarriage
Is it possible to get a pic of the embryo that was transferred?
As I coasted for a week, is there a chance that it damaged the egg quality leading to miscarriage?
Did my mild OHSS increase chance of miscarriage?
What are my chances of a second miscarriage?
Is there any evidence that the miscarriage was due to a problem with my uterus?
Is there a chance that there is a immune issue? If so, can this be investigated?
Could it have been an implantation issue (I miscarried probably at 5weeks), are there any checks for this?
Is it possible that my embie never implanted? (Pregnancy was never located on scan)

Me
Would it be worth tying my tubes in case I have fluid in them? (It wasn't found and I likely had blocked tubes from birth, but still)
How badly blocked are my tubes? Would another HSG be worth trying (to try to unblock minor blockage?)
What are my chances of a viable pregnancy?
What was the condition of my lining? Would a lining scratch be worth trying?
What does me egg reserve look like?

FET
When?
How can I prepare my body?
What protocol for FET?
What drugs?
Can I avoid taking birth control (makes me so ill)
Is there anyway to defrost 2 batches of 2 so that I do not lose chance of a fresh 3rd cycle? (NHS funding dictates that we cannot store eggs, they have to be used for next cycle is available, we cannot pay for anything or it will jeopardise funding)
If chromosomal is assumed, is there a chance that frozen embies have same issue? Is there any way that they can be checked?
Can I have 2 embies transferred?
What are the quality of those frozen embryo's (they are 5 day and 6day blasts, but with the MC I need to know exactly what grades they are - I cannot remember)
What are my chances of a viable FET pregnancy?

Has anyone got anything to add? I'm hoping and praying transfer is end of October my cycles are like clockwork so I'm hoping that they don't have to be controlled. The clinic advises a 3 month wait, but I am not sure 3 months from when? ET? Miscarriage? Mind you I miscarried 1st Aug so 1st nov will be 3 months from that point.

I do know some of the probable answers to these but I do not want to leave any stone unturned. I want them to chuck everything in the 'so you are doing IVF' manual at me. I'm so scared of a BFN or another miscarriage. I do not know which terrifies me more - though I guess we are all scared of that.

Sorry again for the length, one of my objectives for this year (my life year not proper year) is to be more succinct Blush. (And yes, I do talk too much in real life)

Lifeasafish · 13/09/2013 09:14

Shit - thats huge Blush Blush

still, in case you haven't seen it I sent you a pm last week. In my opinion with what you have posted, it may be better to start without your DH if he is unsupportive (and obstructive, in my opinion), but ideally I would say you'll need emotional support. Don't worry to much about physical it took me about a fortnight on burselin before side effects started to show and it was just tiredness and headaches.
My documented my aches and pains well here from may to present if you wanted to look back. I think major downreg major side effects are not a dead cert if I think about the rates of those who cycled here.

I hope thats helpful?

IWantOneNow · 13/09/2013 10:30

Life - that IS a long post, but you know what - it's great! Thank you so much for sharing all those questions with us, coz it makes us think about what we should be asking (I pinched a couple of your questions to ask my Consultant) - thank you Flowers.

eurochick · 13/09/2013 10:56

still I react badly to quite a few drugs but had no immediate bad reactions to the IVF stuff. The burserelin made me feel absolutely awful but that came on over a few days. I've only been on low dose stimms so far, but they just made me a bit moody and bloated. I think you would be a bit ambitious to expect to be back to normal as soon as EC is done though. On one of my three rounds I was in quite a lot of pain for about 36 hours afterwards, and I have heard of people who had far more eggs than me being very uncomfortable afterwards. If you do end up with OHSS, that is when it kicks in.

Would it be possible for you to delay for a month as you are worried about being alone?

bad sedation at my clinic=being completely out. It felt like a GA to me and I had the same issues coming round. Because of that, the third time they used a low dose sedative so I was awake. I could have talked throughout but didn't really care about anything (even when they were panicking and shoving every theatre instrument up me searching for the source of the bleed). There was no breathing tube - just an oxygen mask.

For me I think there were 4 people in theatre - the gynae, the anaethetist, a nurse and the embryologist (who was in and out).

lovesLemonDrizzleCake · 13/09/2013 11:14

Welcome dharma. I am very much a fleeting buddy, but I do try to read everything before responding and failing miserable.

On diet and drink, I drink a little until ET during this FET round, during full IVF I was suffering with headaches loads so I went entirely caffeine and booze free during DRing and stimming, had a sneaky drink or three between EC and ET, went t-total again til the "you are going to loose this non-viable pregnancy" call. I eat a normal healthy diet and exercise regularly, but again not during DRing and stimming as I felt so terrible.

Still I would have struggled looking after a small child by myself, particularly when DRing+birth control pill. But my reaction was extreme - euro and I seem to be on the end of the side effects scale. Also, it does not appear out of nowhere at once, it builds up. So no need to race out to get seen to, but if you are like me, a fair bit of struggle to cope with life.

Iwant that programme sounds interesting. Although I am working from home so it is Not Allowed Wink

AFM I triggered after a glass of wine last night, all set for ET on Wed if the little lembie defrosts okay. My frosties were mostly very high quality, so the first 4 have been frozen singly. I bruised myself, I am totally out of practice injecting, which I think is a good thing. The trigger is to time me with the defrosting embryo. FET for me has involved three follie-scans to check the progress of my normal cycle, the trigger and ET next week. Nothing more, all fairly natural and low-key after the IVF bonanza in June/July.

lovesLemonDrizzleCake · 13/09/2013 11:16

life that list sounds good. Although I'd be curious if they are keen to do all the mc-tests after the first mc. I had a mc at 7+4 last year (after IUI+SO) and a chem diffment this IVF and they've put me off, as I need 2 or more mc's of the proper sort to qualify.

lovesLemonDrizzleCake · 13/09/2013 11:18

And on TMI my trigger has brought loads of EWCM, so SB and I will be trying to make a natural twin to our FET... Although he does not know that yet.

IWantOneNow · 13/09/2013 12:09

A quick question if i may ladies: generally, how many weeks do you inject Menupur for? I'm trying to get a rough calendar together for my cycle. I know it depends on how long it takes for the follies to mature enough - but any rough timings would be helpful?.... thank you! Smile

Lifeasafish · 13/09/2013 12:44

Euro I always want to hug you when you talk about the effects of drugs/EC on you. I hope that’s not patronising, but this is shite enough without having those extra concerns.

Iwant I posted partially for that reason as it goes. That list has been compiled over the past few weeks.

Still I couldn't walk properly for days after EC. 48 follicles and 15 eggs retrieved (the rest had dissolved due to coasting for a week).

loves Thank you for answering the trigger question. It makes sense! I know I do not have a chance in hell of those checks/treatments - I just see it as a closed mouth doesn't get fed, so I may as well ask. Plus the answers may reassure me that it was bad luck. I've my fingers crossed for an intsadiff for you.x

MrFish hasn't had any input to the questions - I think he is scared of me going through more of the same. Wine and discussion this weekend. sigh.

Lifeasafish · 13/09/2013 12:46

Iwant I was gonal-f, but I injected for 5 days if that's of any help whatsoever. A friend of mine has just had a cycle (EC was today) she injected menupur for a week.

Llw2 · 13/09/2013 13:02

So girls just a quick update as I'm supposed to be working after my clinic appointment this morning. I have a cricket team in there. 11 embies all cooking nicely. Scan on Monday and EC on Wednesday (secret yay!)

Llw2 · 13/09/2013 13:19

Iwant, I'm on Menopur and have to inject for 14 days. Half way today!

resipsa · 13/09/2013 15:02

Iwant I did Menopur from the Friday for a week thru to the following Tuesday so 12 days in total.

starsandmoonandback · 13/09/2013 15:27

Life, great questions, I've got a general list I got off FF I can post too in case there are any other questions there for others, although I'm not sure there's much to add! Lol Wink

Iwant, I injected menopur for 10-12 days in my menopur cycles, then you have trigger shot and wait another 36/37hours before ec, so it works out about 12-14 days from start of stimm drugs to ec. But it seems some people react faster, like 5 or 7 days, so it will depend on your body I guess.

I am on phone and have the same problem of personals as I can't see posts once I start writing and I have a memory like a goldfish Shock so hello everyone!

I also suffer terribly on DR drugs, get very very depressed and 'hormotional'. But I don't think I'd mind dh being away for that part as I usually want to kill him, like with PMT Wink

My review apt is on Tuesday. To be honest I'm not sure what he'll say. This cycle was similar to last one and he was so pleased with the way it all went, apart from the BFN Hmm We then have a consultation at my London clinic where I was successful with DS and subsequent pregnancy which ended in m/c. So plan to go back there for a chat, ask about embryoscope, embryo glue and doing another cycle there hopefully at the end of October. Life seems to be one long Ivf cycle! Sigh. I feel better after initial struggle after bfn. I think it's because apts are coming up and I feel like I'm looking forwards to the next cycle now. Oh and I've spent a small fortune on Zita west supplements, hey throwing everything at it! Lost a couple of pounds on slimming world plan since Monday and I've cut down from 3-2 cups of tea (caffeine) every day, planning to go down to 1 (just my most important morning one!) or even try and get to all decaf, but I struggle to properly be awake for the day on a decaf b/fast cuppa Blush

How's everyone else doing on their healthy living side if things? Any nice new recipes to share?? X

starsandmoonandback · 13/09/2013 15:41

Just in case they're any use;

QUESTIONS FOR A FOLLOW UP:

  1. What were the main factors that contributed to this negative cycle?
(well you might as well start with the obvious one!!)
  1. What are this clinics success rates for couples in our position (taking age and diagnosis into consideration)? And what is that statistic nationally?
  1. Eggs:
a) How was the quality of the eggs? (Were they mature enough?) b) Were there as many as you were expecting? c) Would having egg collection a few days earlier or later help? d) Is there anything else that can be done to improve the eggs? e) Can we still do egg share? /Should we consider using an egg donor?
  1. Sperm:
a) How was the quality of the sperm? b) Had the count, motility or morphology improved at all? b.ii) Is there anything that can be done to improve this? c) Would we get better results with SSR? d) Should we consider donor sperm (or ‘donor back-up’)? e) Should we consider an appointment with an urologist? (Whom would you recommend?)
  1. Embryological questions:
a) How did the embryologist feel the ICSI procedure went? (E.g. was it easy to find sperm of good morphology in the sample?) b) How well did fertilization go? (E.g. more quickly or slowly than expected) c) Did any fertilized eggs produce unusual results? (E.g. 3 nuclei) d) What was the overall quality of the embryos like? e) How do you grade them/what is your opinion of grading vs. live baby rate? f) Does any of this suggest any issues? g) Could assisted hatching help us? h) Would delaying transfer (or carrying it out earlier) have helped? i) What is your opinion on going for blastocysts next time? j) Can the embryologist remove the fragmentation in the embryos? k) What do you feel the link is between fertilisation rate, embryo quality and live baby rate? l) What is the policy with regard to freezing/frozen embryos?
  1. The drugs:
a) How do you feel I responded to the drugs for down regulation? (Did it take longer or less time than expected?) b) How do you feel I responded to the drugs for stimulation? (Did I respond too quickly or too slowly? Did I produce enough eggs? Did coasting for a few days effect egg quality?) c) Did the trigger injection work as expected? (Should I have taken it earlier or later for better results?) d) Do you feel I am on right drugs at the right dose or should this be changed next time?
  1. Further tests:
a) Are their any further blood/hormone tests you would now recommend? (E.g. FSH, E2, etc.) b) Should we test for immune issues? c) Should we test for sticky blood? d) Should we have any further genetic tests? e) Would you recommend having a hysteroscopy? (Why?) f) i) Would there be any point to do PGD? ii) How many embryos to you need for this? iii) What are the risks involved? iv) Is each embryo tested for one genetic disease or 9 of the listed diseases?
  1. Next cycle:
a) When can we try again? (Why then?) b) i) Which drugs for down-regulation? ii) Why do you feel this one would be better? iii) What dose? e) i) Which drugs for stimulation? ii) Why do you feel this one would be better? iii) What dose? f) Would you recommend any additional treatment this time? (E.g. low doses of aspirin, IVIG, heparin, etc.)
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