TTC or pregnancy on prednisolone or similar part 9

[sarahs999]

Oh dear - we reached 1000 posts on thread 8 without noticing! I hope you can all find this. THis is a positive thread for all those diagnosed with High or Very High NK Cells and looking to start TTC or already pregnant on Prednisolone and/or Intralipid treatment.

Newcomers very much welcome!

Links to earlier threads:

Part 8: www.mumsnet.com/Talk/conception/a1492407-TTC-Pregnancy-on-Prednisolone-or-similar-part-8#33842381

Part 7 www.mumsnet.com/Talk/conception/1452035-TTC-Pregnancy-on-Prednisolone-or-similar-part-7

Part 6 www.mumsnet.com/Talk/conception/1419032-TTC-Pregnancy-on-Prednisolone-or-similar-part-6

Part 5 www.mumsnet.com/Talk/conception/1391787-TTC-Pregnancy-on-Prednisolone-or-similar-part-5

Part 4 www.mumsnet.com/Talk/conception/1366323-TTC-Pregnancy-on-Prednisolone-or-similar-part-4

Part 3 www.mumsnet.com/Talk/conception/1348773-TTC-pregnancy-on-Prednisolone-or-similar-part-3

Part 2 here www.mumsnet.com/Talk/conception/1323594-TTC-pregnancy-on-Prednisolone-or-similar-part-2

Part 1 here www.mumsnet.com/Talk/conception/1236324-TTC-pregnancy-on-Prednisolone-or-similar

welcome cartoon. I started the day after OV as indicated on a stick but only because I was a bit nervous taking the steroids.

Kitten, the pred is not expensive on pvt prescription at all just. Make sure you specifically ask for 5mg.

Sue hope all goes well for tomorrow and Friday.

Free good to hear things are going well. I do remember a distinct shift at 3 months and 6 months things seemed to get so much easier. Admittedly it depends on whether you have a sleeper or not. Which reminds me, this is dc 2 but still terrified. I think I'm just a born worrier.

Not sure who asked but I also wondered how snoopy was. If you ever pop in do let us know you're ok?!

Thanks ladies. Yes I will be having the intralipids. Is it horrible? I'm abit scared of it all, the side effects etc

Hi everyone, welcome cartoon.

I've been worrying and stressing, I started taking pred this cycle two days after positive opk, as I started temp charting too which just made it more complicated! So was worrying I took the pred one day too late but hopefully as free said one or two days won't matter.

I've always got pregnant within three cycles, usually on first go, so if I don't get pregnant on this third cycle I'll be worried that the pred is messing up my attempts as has happened with some others of you on here I think.

I'm also going to need pred on private prescription this time I think as i'm having difficulty getting it on nhs, so that's good its not too expensive.

Basically i'm stressing all of the time, about getting pregnant and worrying already about if the treatment is going to work. Its mental torture isn't it!

Hello girls

Would you mind if I asked you a predisolone question ?

Am about to start a second IVF round. After the first one failed I had immune testing which showed (slightly) elevated NK cells. Am going to whole hog with medication (asprin, intralipids, clexane and predisolone).

It's the thought of steroids that really makes me shudder !! When I screwed my nose up at the Consultant at the mention of them he told me that the dosage would be low and I wouldn't be on them long enough to develop a big moon face or turn into a bodybuilder (or something to that effect !)

Our medication was delivered yesterday and out came one box of predisolone, and then another. 15 boxes (or 420 tablets later !) they were in a pile on the table. The literature suggests that I have to take 5 tablets a day (5mg tablets)

Anyhow - after all that wittering my question actually is - is that dosage normal ?????????? Seems a lot to me ............. !!

Thanks in advance xxx

Hi missbrightside, it's a perfectly normal dose. 25mg for high nkc, 40ml for v high nkc.

As for being nervous, that's perfectly normal too. We all were when we first started. Then three months later you'll be nervous to come off them! You've done the right thing by throwing all those meds at it - if nkcs are your problem there's no point spending all your money and emotion on ivf, as the nkcs will more than likely end the pregnancy. Instead of fearing the roids, see them as your savior! I'm currently 14 weeks pg after 5 mcs; prednisolone certainly helped me. Do ask away with any more questions, and good luck!

Hi miss brightside, welcome to the thread. Yes that is a normal dose. Most of us here are/were on the same - 25mg - with some, myself included, going up to 40mg on getting a positive pregnancy test. For some reason your doc has given you 25 mg but in 5 tablets, so it just seems like a lot.

This answers Mollie and Cartoon too really but don't worry about the steroids. They do come with some annoying side effects but you're hopefully on them for a relatively short amount of time. I did put on a few pounds as I found I was v hungry but it was only when on 40mg that I got a bit of moon face! And it does go very quickly when you stop taking it. I also got some aches and pains when weaning but again nothing really scary. Oh and at first you might not sleep v well. Other people find they feel great on them! Full of energy and things like allergies going.

Intralipids are rather relaxing, once you get the drip in. And that doesbt hurt either. There are no side effects, it just feels a bit surreal being wired up to a drip when not ill!

Crossed posts with Sarah - yes, once pregnant we've been nervous to come off them! But that has been fine too. And it will be handy that you have your tablets in 5mg form for tapering.

Thank you so much for your responses. I feel a bit better about it all now ....... !

(I will let you know if I turn into Geoff Capes ..................... !!!)

moonface! dear god, ok it will all be worth it. im so scared of mc again even though im on all these meds. weve always seemed to get pregnant quickly so hopefully will this time too!

Has anyone had trouble getting pregnant when on pred when they didn't before they took it? The nurse at the clinic said it shouldn't prevent pregnancy if you take it after ovulation and only for 10 days and then stop if not pregnant but I think I have read of one or two saying it did stop them getting pregnant....

Hi missbrightside, its all good fun isn't it. Best of luck with your ivf treatment. I'm taking 10 tablets every morning at the moment with the pred, aspirin and vits but it'll all be worth it I'm sure! I was nervous taking steroids too but haven't had any side effects so try not to worry too much.

Rooting for sue today, hope the specialist gives you some hope ...

Thinking of sue. Hoping beyond hope x

Loads of luck for Friday Merc. Hope it goes really smoothly.
Massive congratulations to PQ and frozen on the birth of your boys. The thread is definitely in roller coaster mode.

I have another scan on Fri. Its unlikely to be good news so will need to decide whether to have an ERPC, I have mc'd naturally 6 times but I dread that again, it's the when that's haunting at the moment. My oh is in the forces so largely absent so would like a little bit of control, particularly as I have to look after my little people. I'm aware that erpc's have their drawbacks...any thoughts?? Emotionally I'm in a rubbish place but I know you don't need that clarifying, we've all sadly been there.

cornflake how are you? We are in a similar place right now, I think?

On the steroid front, they work ok for me, more energy, my boys sleep appallingly so I actually cope a bit better. Asthma virtually gone and no hayfever (I'm normally hideously affected in early preg) I get awful tinnitus on them! The biggest downside for me is rage. Real blind rage.

Clabbage what you're describing we know on here as Roid Rage :)

Talking of Pred helping with allergies/hayfever etc, I'm rather ironically now on 25 mg Pred to relieve my bad allergic reaction to Humira. Talk about going round in circles!! Will be interesting to see if just one dose has made any difference to my TNF alpha.

sue thinking of you today - wish there was something I could say to make it easier but just know you're very much in my thoughts.

No hope for us as kidney damage is too severe in both kidneys. Probably won't be on here for a while but thanks for all your messages.

Oh sue, I'm so very sorry for the bad news. Life really is shtty, words fail me. Huge hugs*, stay strong and take care of you.

choccy Now there's irony for you! Are you still going ahead with the second dose, if you had such a bad reaction to the first?

Hi Kittens I think I paid approx £10 in boots for 1 months supply of pred. 40 mg.

Sue sorry to hear your news. I am thinking of you at this sad and anxious time.

PQ congratulations on the birth of your son and it sounds like a good weight.

Hello to everyone else. I am 5 weeks 1 day today and yesterday evening I had watery, pinkish red blood. This morning it wasn't there but it has come back this afternoon. I think this one is going to be doomed. I read loads of stories about other people having bleeds at 5 weeks so I am still clinging onto some hope that it will be OK but realistically I have seen it so many times before. I wish I could cry but I can't. Just really disappointed at the moment. At least I know I had every drug possible this time round. There always seems a run of good luck on here followed by a run of bad luck. I am so glad I can tell you how I feel as you are the only ones that truely knows how it feels.

Abney I shan't tell you not to worry but it could be implantation or cyclogest.... Fingers crossed and feel free to mental on here, we have indeed all been there with good and bad results.

sue I'm so very sorry that's awful horrible news.

Ari nope. He won't risk it as another dose would likely give me an even worse reaction. Anaphylaxis is not somewhere I want to go...! The blood test is more just out of interest therefore. I'll have a chat with him tmrw and put a plan together to get started again. Back in the saddle soon either way :) and

I so wished Sue's news was going to be different.
Sometimes the unfairness of this all is overwhelming.

abney Without wishing to be personal, are you using the visitor's entrance for the cyclogest or the tradesman's? I've heard a few ladies saying they got an irritation with using the visitor's entrance for cyclogest, could it be that? Hang in there until you know one way or another, but if you are using that particular door for the cyclogest, perhaps swap to the other and see if that makes a difference?

choccy Here for handholding when you're ready. Well not while you're actually in the saddle, if you know what I mean ... ! ;)

Abney, I had a gush of watery pinkish blood quite soon after my BFP and was convinced it must've been a chemical. I hope all is ok for you.

Sue, I'm so so sorry. I will PM you in case you are not really looking in on the thread. I know this can be a difficult place to check in to with what you are going through. I just wanted you to know that I got an immense amount of support and empathy from the support threads on the Antenatal Test/Choices boards here. They really have been a lifesaver for me in the last few years. I'm sure you are absolutely reeling trying to get your head around what life has just thrown at you.

Thanks for the replied about the pred. A lovely "benefactor" has offered to send me some that she is not using .

Choccy, that really is ironic. Sorry to hear you've reacted badly to the Humira. I hope you're OK. Sounds like a nasty drug!

Ah yes, I'm very familiar with Roid Rage! Raaaarrrrghhhh! I'm pleased to say that I only have a very gentle case of moonface which probably came on about 8+5 and I am in the process of weaning off so hopefully that will deflate soon.

sue so very sorry to hear your news. Big hugs xx

igsisgreenngold Is that you iggi???

Hi all. Thanks for your kind words. Funny enough it is the kind words from others that make you want to burst into tears. I am guessing the visitors entrance is the front entrance and the tradesmans entrance is the back door. If so the cyclogest goes in the front entrance.
I have a pg test which I am going to use when I get home to see if it goes up a week. My motherinlaw will say to me when I get in. Are you OK? And I will say yes I am fine. If she looks closely she will see that I give my DS an extra tight squeeze. She won't sleep tonight if I tell her so there is no point until I know for sure. Kittens I remember you said you had pinky blood and I myself had a gush of pure red blood last time. The very next day I had a scan and could see a strong heartbeat (although I lost it in the end). Does anyone thing I should ask DR S for a scan tommorrow or Friday to put me out of my misery one way or another. Has anyone else done this before when they have had an early bleed? I usually go to the NHS but I think I would rather pay the money for someone who is more understanding.

Hi abney, so sorry for you going through all this worry, its not fair is it. I would definitely get a scan somewhere, I know what you mean about having one with someone who understands your situation a lot more. I always use the CB digi pregnancy tests too when I'm pregnant to make sure the weeks go up, but they really can be mental torture. In my experience its best to use it with first morning pee instead of in the evening as if your pee is watered down then the results might upset you when there may be nothing wrong at all...x