TTC/Pregnancy on Prednisolone or similar part 8

[Arianrhod]

A positive thread for all those diagnosed with High or Very High NK Cells and looking to start TTC or already pregnant on Prednisolone and/or Intralipid treatment.

Newcomers very much welcome!

Part 7 www.mumsnet.com/Talk/conception/1452035-TTC-Pregnancy-on-Prednisolone-or-similar-part-7

Part 6 www.mumsnet.com/Talk/conception/1419032-TTC-Pregnancy-on-Prednisolone-or-similar-part-6

Part 5 www.mumsnet.com/Talk/conception/1391787-TTC-Pregnancy-on-Prednisolone-or-similar-part-5

Part 4 www.mumsnet.com/Talk/conception/1366323-TTC-Pregnancy-on-Prednisolone-or-similar-part-4

Part 3 www.mumsnet.com/Talk/conception/1348773-TTC-pregnancy-on-Prednisolone-or-similar-part-3

Part 2 here www.mumsnet.com/Talk/conception/1323594-TTC-pregnancy-on-Prednisolone-or-similar-part-2

Part 1 here www.mumsnet.com/Talk/conception/1236324-TTC-pregnancy-on-Prednisolone-or-similar

free I can imagine how difficult that must have been. I think you should tell them what you have been through at the next session. After all, you are hoping these will be your "baby friends" so it will come out at some point.

PQ I'm due to start downregging next week. Still not happy about it, but will probably force myself to get on with it!

Hey lovelies. Just out of hospital after ERPC. So glad it's over as was having nightmares about it going wrong. I think you are all amazing mummies who show such strength and courage - the stats are proof of that. Hope I can find some. Feel all out right now.

Interested in the views being expressed at the end of part 7 re choosing between Dr S and Dr G - I struggled to decide and wondered what your experience/opinions are?

Free - can empathise with how you feel. Before I lost Amelia Rose people would ask/say very normal things to me like how exciting/when are you due etc etc and I used to have to battle back the tears and say things like 'if all goes well' or 'if the baby makes it' - people didn't like it and told me not to worry.........so much for that eh :-(
This all changes us so much and we lose all innocence/naivety but gain gratitude and empathy with others in bucketloads - I think it's what will make each and every angel parent such amazing earth parents. Big hug

Xxxxx

thanks for the link
freelancegirl im new to this, i find it very helpful looking at all the historys of you girls especailly with the positive outcomes some of you have had. I just waithing to get the courage up to try again.
sue really hope it goes well on thursday will be thinking of you

one question not sure if anyone will know the answer Dr s said all my losses are chemical pregancies but i thought that was when they didnt implant, my scan show collpased sack so surely something implanted, i bleed between six and seven weeks.

Sorry you are feeling down Kittens and *Picolina, wish I could say something to make you feel better so will send virtual hugs instead.

Free I can totally understand why you burst into tears, it's all such an emotional roller coaster. I second Euro and think you should tell them. Sending you a big hug also.x

Good luck for next week Euro and I promise it won't be as bad as you think.

I am not doing super ov this month but trying naturally, kind of! I am not temping and not bothered with ov sticks as never work! Just wondering if I could just take pred anyway around time I normally ovulate?? Has anyone else done this?? Also Free when you have a min could you send me that pred?

Waves to everyone I have missed, has been busy on here today!

pebbles, considering I tend to take the pred a couple of days after my surge on the OPK sticks it's not exactly an exact science either. I'd say you should be ok. I've always been inclined to take it just after I think I've ovulation though as there has been a lot of talk on here about it delaying ovulation.

echo, I don't think I said hello when you first joined as I was posting from my phone. I am glad your ERPC went smoothly but very sorry for your loss.

gransol, I'm afraid I don't know the official answer to your questions but like you, I would think that if there is a gestational sac it would indicate there was implantation.

Very heartbreaking to read of all those losses.

For anyone else reading this, and for comparison purposes, I'm another no-BFPer and just VNKC diagnosed so far, which Mr S said could be the cause of repeat implantation failure as well as repeat MC's.

had doc appt today, going back thur for blood test, going to test for thriod or any other autoimmune probs, she seems to be a good doctor so lets hope we will get to bottom, she didnt think it was a good idea to go back on steriods until we get to bottom of it .

kittens im sorry you feeling crap as well, i lost my dad nearly 20 years ago and when i think about it it still makes me cry, same with my brother, it took 6 mths before i stopped cyring every night, you will get to a point where you can cope , in your own time.

sue i hope everything is ok and you keep getting good news .

free you made me cry when i read about your meeting , i know how you feel , im ok if i dont have to talk about anything into much detail esp to people i dont know, if i do i become a blubbering mess its naturala nd if you told them your story i think more than 1 person is going to be teary

i noticed i mentioned the would cry a lot, it IS the bloody weather!!!!! freaking rain..go away!!

forgot to mention got an email from dr trevor wing assistant, they have mid july free, im going to go and see what happens ... i will do this without crying !!

gransol I agree with kittens - I think a visible sac = implantation. My understanding of a chemical is that sperm has met egg to create an embryo but that it didn't implant. On a couple of my early mc I had v v early scans to rule out ectopics, eg 5+5, and you could see the sac + fetal pole. I don't think of them as chemicals.

echo glad the op went well. Do keep us posted on how you're going if you feel up to it.

free i think my earlier post didn't make sense. I think it would be good if you did give more details when you next meet and I think it was healthy that everyone could see that not everyone was ecstatically happy when you did your little group sharing thing. Echoes of my pilates class - please join me this saturday and burst everyone's happy bubble (I don't mean that, really).

Yes, I did see the vege and mc thread. Agree that the diet for this poor woman is most likely not the issue at all but...one of my conception books does warn about having masses of soy based products as the dr does think it can interfere with hormones in some cases. But prob better than a number of other things people ingest! I haven't posted on that thread as I'm just not qualified and I think diet is such a minefield (feel happy discussing it here though )

Hello. Thank you for new thread. Just marking my place before I head off to bed. I've been following the thread on my phone but I can't type on it properly as it's a bit old, so I haven't been able to reply to anything.

Brownie - Huge congratulations to you and Mr Brownie! I hope you're making a swift recovery and enjoying lots of lovely cuddles.

Echo - Welcome and sorry to hear about your loss. Good to hear the ERPC is over and done with. I think that waiting around in limbo is just horrible isn't it. I hope you've got lots of RL support over the coming weeks.

Free - I don't think it does anyone any harm to realise what an uphill struggle some people have to get to the NCT stage, but I would say you should only share with those people if you feel happy doing so. You don't owe them any kind of explanation unless you feel you want to. It's odd (or not really, I suppose) how you think you've got things under control and it just comes back and gets you when you're not expecting it. FWIW - When I got into the delivery suite when I was having ds2, I collapsed into tears and got myself into a right old state. The poor midwife thought it was just because I was frightened of being in labour and kept trying to reassure me about pain relief etc, whereas I think I was just letting out a lot of the stuff that I'd been trying to keep a lid on throughout the pregnancy.

Sorry you are feeling low Kittens and Pico. This miserable bloody weather doesn't help lift anyone's mood either.

Hello to everyone else.

Hello everyone, I'd like to join this thread please, I've been reading it for a while. I'm not on steroid treatment but do have an appointment for testing soon.

My history is as follows over the past two years:

mc at 6 weeks
mc at 10 weeks
mc at 5 weeks
Gave birth to my beautiful baby boy at 29 weeks, he died at 5 months old, he was born prematurely due to blood clots discovered in the placenta which prevented him from growing inside me - took progesterone from 6-14 weeks and aspirin throughout the pregnancy
mc at 6 weeks - on aspirin and Clexane
mc at 5 weeks - on aspirin and Clexane

I'm feeling at rock bottom, but this thread gives me hope for the future.

I get pregnancy very easily but my body will just not do the rest of its job.

I'm booked in with Dr Shehata next week and will get the results back soon. I hope I have high NK Cells, otherwise I will be very worried as I'm not sure what else to do from here as I've had all NHS testing and nothing has been diagnosed. Blood clotting was diagnosed when I gave birth but the treatment has not worked.

I'm also starting acupuncture to help restore some balance and harmony to my life, goodness knows I need it.

Well done to everyone on here, we are going through or have been through such a lot of heartbreak. Its lovely to support each other through the tough times and its just wonderful to see people coming out of the heartbreak with their beautiful babies xx

Hi all,

Sorry Gransol I must have missed your arrival on the thread when we changed to the new one. I thought you might be a name changer so didn't give you a proper welcome. Hello! And welcome to the thread. I will add you to the list. I would agree with the others - a visible sac means implantation. I have never had a collapsed sac but last mc was a sac that didn't grow. Mr S told me that although there was no foetus seen there would have actually been one there, just a very small one. Not sure if that is the same with a collapsed sac. I think Pebbles also had the same - no foetus seen but post-erpc tests came back showing there was definitely one there.

And yes CareBear when I have interviewed Mr S I got the impression that having no BFP was definitely something that can be related to HNKC - that they have attacked so early that there was no chance of implantation.

Glad the op went well Echo and that it is over and done with. It's a crucial step in trying to move on and get to the next stage as you know. That must have been so awful with Amelia Rose. I really feel for you and hope you get some answers soon.

Pico great that you have an appointment with the Trevor Wing people! Yes it's funny how these things can hit you at any time. Same for you Coconut, we manage to be strong a lot of the time and then when it hits you it can take a while to pull it together. Let me know what your blood tests results show when you get them! Remember you want the actual numbers.

PQ I would love to come on Saturday but am oop north for a Christening. Actually two of my NCT group go to the same classes but I think one on Tues even and on on Thurs lunchtime. I would really like to start going again soon, must sort that out. Together we would make a formidable team when it comes to freaking out the happy pregnant folk :)

Euro good luck with the down regging. From what Pebbles says it is not as hideous as you might think.

Will def post the drugs Pebbles :) Hope you had a great weekend in Paris. Yes, start taking them around the time you think ovulation would be. It's not an exact science so give or take a few days it doesn't hurt at all. Will text you tomorrow anyway xx

Crossed posts with you Mollie. Welcome to the thread, but oh my goodness what an awful thing you have been through. I cannot imagine what is must have been like to lose your little boy at 5 months old. You poor, poor thing.

Is there a theory that the clotting issue was related to the problems you have been having with miscarriages too? I do hope you get some answers from your appointment next week. Overall I think you will find Mr S very soothing. He really knows his stuff and I hope that he and of course the tests can help give you hope for the next pregnancy.

So sorry you are at rock bottom, it's a terribly sad place to be. I really hope you get some answers very soon and that something like high nk cells is discovered so you can begin some sort of treatment.

Please stay around and chat with us. I really do hope we can be of some help here. We are, if nothing, very well researched and everyone is so supportive. One of our members has also lost a child (as opposed to a pregnancy, although she has had recurrent mcs too) but she has just had a new baby so might not be about for a while.

Hi Free, thank you for your reply.

Losing my little angel has been so tough, but on the other hand I feel so blessed to have given birth to him, he really is my hero and was so brave and strong. He's my inspiration and keeps me strong.

I've bought the Alan Beer book after reading some forums, and he said that clotting issues can be related to other immunology disorders such as NK Cells, so I'm feeling hopeful that Dr S will be able to look into all of this and sort me out! I live in Wales but again found out about Dr S from looking at forums and seeing the succes stories.

I'm so pleased that you're having a good pregnancy after everything you've been through, it was probably very tough having another miscarriage after starting treatment but its wonderful that you're where you are now. I can totally imagine how emotional you are feeling, the luxury of only being excited throughout pregnancy is taken away from us when we go through so much beforehand, but all is well for you which is amazing.

Its great to know that the person you are talking about who lost a baby and had miscarriages has now had another baby, I'm so pleased for her. Its awful to know that other people have gone through as much as me but also its nice to know I'm not alone and that there is light at the end of the tunnel.

Hi Ladies - thought I'd add my history of 4 mc's to the list.

Tuesday 12th June

The babies are arriving!

Stogan - V high NKC - cycle#2, DC#1, Baby girl Ellyson (DC1) born Sunday (EMCS) 11/03/12 7lb13.5.
Digitalgirl - High NKC - BFP cycle#2, Baby boy Franco (DS2) born at 39+0 on Easter Monday, 9/04/12, 8 lbs 12
Coconutfeet - V High NKC, Factor II gene mutation, underactive thyroid - BFP pre-pred, started at 6 weeks, Baby boy Arthur born at 40+6 13/05/12 3.66kg
Comedy - V High NKC - BFP cycle#2, baby girl Matilda born DC#2 ? 39 weeks (ELCS) 14/5/12 7 lbs.
Igggi - High NKC & Hypothyroidism - BFP cycle#2, DC#2- Baby boy Thomas born (ELCS) at 38+6 16/5/12
BrownieGecko - High NKC, Hypothyroidism, & Glucose Intolerant. BFP Clomid cycle#3, DC#1 40+0 - baby girl Amelia born 7/06/12 (ELCS) 7lbs

BFP 3rd Trimester

Freelance - TTC#1 V High NKC Thyroid/hashimotos - 4mcs (one on 1st Pred cycle) heart stopped around 7-8 weeks, Hydroxy, Pred, Intralipids, Cyclogest, . DC#1 34 wks Next appt/scan, 22nd June EDD 24/07/12 by LMP, 22/07 by Nuchal
Cheerfulcharlie - TTC#1 V High NKC, MTHFR, DC#2/ (metformin, intralipids, no pred). 34 wks EDD 24/07/12
batteryhen - High NKC, factor v leiden. DC#1 BFP cycle 3. 30+6
coleyoz - V High NKC. DC#2, BFP cycle2, 30+1

2nd Trimester

FrozenNorthPole - RMC, NKC status unknown, Cyclogest, aspirin, 25+6
Mercator - V High NKC, TTC#2. 25+4
Hopefulfor2nd - High NKC - TTC#2. - 24+6
dunnit - V High NKC - , IVIG, Cyclogest and Clexane. 24+6
PQ77 - TTC #2, 2 mcs, then DS, followed by 4 mcs - 6-8 weeks. V High NKC (BFP cycle one but mc) 20+2 Next scan @ 20 weeks

1st Trimester

HelterSkelter (IVF and immune therapy) 9+4

To be added to shortly...

TTC ? ASSISTANCE - SO/IUI/IVF

Suemays - TTC#2 DD, followed by 5mcs all 6-8 weeks. V High NKC, TTC #2. Superov. (Pred & Hydroxychloroquine) 6+6 Scan 14th June

EchoJuliet Preg 1 - awaiting diagnosis, MC 10 weeks (heartbeat stopped at 6w), mc 20w, mc at 8 weeks (heartbeat stopped at 6.5w).
Pinkdragon - High NKC. Pred Daughter (after 4 mcs) TTC #2, super ov.
duggs1976 - TTC#1 4 mcs all 7-12 weeks. High/V High NKC - TTC #1 - IVF cycle #1 ?pred, intrallipids, metformin, clexane, cylogest
Havingkittens - TTC#1 4mcs between 6-8 weeks, 2 Downs. Upgraded from High to V High NKC -10 pred ? 3rd cycle SO
Abney (44), TTC#2, SO 2, 6 MC No pred (2 chromosone, 4 unexplained), 1 DS Pred Cycle 1 & fragmin, 4 MC on Pred (1 fragmin),
eurochick - TTC#1 High NKC, pred cycle 6, had 3 cycles of Super Ov, now on 2nd cycle of IUI No BFP in 20+ cycles of trying
Pebbles - TTC#1 High NKC, PCOS, super ov cycle 1 (post IVF - 1 chemical, 1 mc, 2nd chemical on treatment/IVF
Arianrhod - TTC#2 DD then 5 mcs 5-9 wks (2 on treatment), V High NKC, MTHFR homo, hypothyroid, TTC#2 (Pred & Hydroxychloroquine)

TTC
London - High NKC, April - mc on treatment.
ChoccyPud - V High NKC - TTC#1 (Pred & Hydroxychloroquine). April - mc on treatment.
Willitbe - TTC#4 DS, DD, 1 mc, DS2, followed by 11mcs, gen 6-8 weeks. NKC not tested, TTC #4 cycle 2 (after m/c 12) Fertility consultant
prescribed pred.
GreenOlives - TTC#2 DS followed by 2mcs, 1 ec, 1 chem. High NKC, decided to only take Pred from BFP
picolina - TTC#1 4 mcs, all around 6 weeks. V High NKC MC on treatment
Holldoll - TTC #2 High NKC - Pred, Cyclogest & aspirin. DS followed by 4 mcs, heart stopped around 5-6wk. Mc in March 2012 on treatment. Pred started at BFP.
Lemonsherbet - TTC#1 v high/high NK, Mthfr, thyroid issues, pred 1st trim & Intralipids 2nd on bfp
buster76 -V High NKC, Factor V Leiden.
BellyD - V High NKC, MTHFR homo, TTC#1 cycle 2, hydroxychloroquine
ScooterChaser - V High NKC - TTC#2 (Pred & Hydroxychloroquine)
Carebear1 - V high NKC

Current status?

Cherrycheeks - V high NKC, TTC#2
Breezyweezy - V High NKC - TTC#1
AandRmum - High NKC
Cornflakes30 - V High NKC, underactive thyroid
Brownstag - V High NKC, 3 yo DS is a Pred Baby! TTC #2
Zoeella V.high NKC, Factor V Leiden. abandoned IVF, pos PCOS\

Gransol - Seven mcs - all losses between 6 & 7 weeks

Hi All - updated this time. Too busy trying to update list.

Tuesday 12th June

The babies are arriving!

Stogan - V high NKC - cycle#2, DC#1, Baby girl Ellyson (DC1) born Sunday (EMCS) 11/03/12 7lb13.5.
Digitalgirl - High NKC - BFP cycle#2, Baby boy Franco (DS2) born at 39+0 on Easter Monday, 9/04/12, 8 lbs 12
Coconutfeet - V High NKC, Factor II gene mutation, underactive thyroid - BFP pre-pred, started at 6 weeks, Baby boy Arthur born at 40+6 13/05/12 3.66kg
Comedy - V High NKC - BFP cycle#2, baby girl Matilda born DC#2 ? 39 weeks (ELCS) 14/5/12 7 lbs.
Igggi - High NKC & Hypothyroidism - BFP cycle#2, DC#2- Baby boy Thomas born (ELCS) at 38+6 16/5/12
BrownieGecko - High NKC, Hypothyroidism, & Glucose Intolerant. BFP Clomid cycle#3, DC#1 40+0 - baby girl Amelia born 7/06/12 (ELCS) 7lbs

BFP 3rd Trimester

Freelance - TTC#1 V High NKC Thyroid/hashimotos - 4mcs (one on 1st Pred cycle) heart stopped around 7-8 weeks, Hydroxy, Pred, Intralipids, Cyclogest, . DC#1 34 wks Next appt/scan, 22nd June EDD 24/07/12 by LMP, 22/07 by Nuchal
Cheerfulcharlie - TTC#1 V High NKC, MTHFR, DC#2/ (metformin, intralipids, no pred). 34 wks EDD 24/07/12
batteryhen - High NKC, factor v leiden. DC#1 BFP cycle 3. 30+6
coleyoz - V High NKC. DC#2, BFP cycle2, 30+1

2nd Trimester

FrozenNorthPole - RMC, NKC status unknown, Cyclogest, aspirin, 25+6
Mercator - V High NKC, DC#2 25+4 (Pred, Intralipids, Cyclogest) 4mcs (1 pre dd, 3 post - all at 6-8 wks)
Hopefulfor2nd - High NKC - TTC#2. - 24+6
dunnit - V High NKC - , IVIG, Cyclogest and Clexane. 24+6
PQ77 - TTC #2, 2 mcs, then DS, followed by 4 mcs - 6-8 weeks. V High NKC (BFP cycle one but mc) 20+2 Next scan @ 20 weeks

1st Trimester

HelterSkelter (IVF and immune therapy) 9+4

To be added to shortly...

TTC ? ASSISTANCE - SO/IUI/IVF

Suemays - TTC#2 DD, followed by 5mcs all 6-8 weeks. V High NKC, TTC #2. Superov. (Pred & Hydroxychloroquine) 6+6 Scan 14th June

EchoJuliet Preg 1 - awaiting diagnosis, MC 10 weeks (heartbeat stopped at 6w), mc 20w, mc at 8 weeks (heartbeat stopped at 6.5w).
Pinkdragon - High NKC. Pred Daughter (after 4 mcs) TTC #2, super ov.
duggs1976 - TTC#1 4 mcs all 7-12 weeks. High/V High NKC - TTC #1 - IVF cycle #1 ?pred, intrallipids, metformin, clexane, cylogest
Havingkittens - TTC#1 4mcs between 6-8 weeks, 2 Downs. Upgraded from High to V High NKC -10 pred ? 3rd cycle SO
Abney (44), TTC#2, SO 2, 6 MC No pred (2 chromosone, 4 unexplained), 1 DS Pred Cycle 1 & fragmin, 4 MC on Pred (1 fragmin),
eurochick - TTC#1 High NKC, pred cycle 6, had 3 cycles of Super Ov, now on 2nd cycle of IUI No BFP in 20+ cycles of trying
Pebbles - TTC#1 High NKC, PCOS, super ov cycle 1 (post IVF - 1 chemical, 1 mc, 2nd chemical on treatment/IVF
Arianrhod - TTC#2 DD then 5 mcs 5-9 wks (2 on treatment), V High NKC, MTHFR homo, hypothyroid, TTC#2 (Pred & Hydroxychloroquine)

TTC
London - High NKC, April - mc on treatment.
ChoccyPud - V High NKC - TTC#1 (Pred & Hydroxychloroquine). April - mc on treatment.
Willitbe - TTC#4 DS, DD, 1 mc, DS2, followed by 11mcs, gen 6-8 weeks. NKC not tested, TTC #4 cycle 2 (after m/c 12) Fertility consultant
prescribed pred.
GreenOlives - TTC#2 DS followed by 2mcs, 1 ec, 1 chem. High NKC, decided to only take Pred from BFP
picolina - TTC#1 4 mcs, all around 6 weeks. V High NKC MC on treatment
Holldoll - TTC #2 High NKC - Pred, Cyclogest & aspirin. DS followed by 4 mcs, heart stopped around 5-6wk. Mc in March 2012 on treatment. Pred started at BFP.
Lemonsherbet - TTC#1 v high/high NK, Mthfr, thyroid issues, pred 1st trim & Intralipids 2nd on bfp
buster76 -V High NKC, Factor V Leiden.
BellyD - V High NKC, MTHFR homo, TTC#1 cycle 2, hydroxychloroquine
ScooterChaser - V High NKC - TTC#2 (Pred & Hydroxychloroquine)
Carebear1 - V high NKC

Current status?

Cherrycheeks - V high NKC, TTC#2
Breezyweezy - V High NKC - TTC#1
AandRmum - High NKC
Cornflakes30 - V High NKC, underactive thyroid
Brownstag - V High NKC, 3 yo DS is a Pred Baby! TTC #2
Zoeella V.high NKC, Factor V Leiden. abandoned IVF, pos PCOS\

Gransol - Seven mcs - all losses between 6 & 7 weeks

Mollie Welcome - so sorry to hear what you've been through. I do hope Mr S has some answers for you. As Free says he is a lovely man and I am sure will do his utmost to help you.

I feel very fortunate to have been able to research this myself and find him as I find that the NHS Consultants and even my own GP yesterday have so little interest in NK cells which I still find absolutely astounding! Yet they must see this every day.

sue Good Luck with the scan on Thursday.

On a personal note I have my obstetrician appt so hope I will have a date for my c-section before I go off on hols this weekend.

Morning ladies, just a very quick Hi from me as I'm buried in work at the moment.

pico Just wanted to share this with you re: the chinese mushrooms/herbs that Dr Trevor Wing uses. I've been communicating with the very helpful Penny at the Serum clininc in Athens, as I'm going to get tested for hidden C/mycoplasma/ureaplasma (and a few other infections that I forget) with my next AF, and she asked for and kindly looked over my whole history. One of the things she said in response was this:

"Also, we have had patients with high NK killing power who were unsuccessful with steroids but conceived naturally after taking a herbal mushroom programme prescribed by Dr Trevor Wing in the UK (1.5g per day of cordyceps, coriolus and reishi). This may be something you could consider.".

So that gives me even more confidence that these are the right things to take. They were dispatched to me yesterday, so hopefully I should be able to start taking them in the next day or so. I really hope they do the trick, I feel very vulnerable without the prednisolone pre-conception! Always assuming I ever do get another 'proper' BFP, of course.

mollie A big Hello to you, and I'm so very sorry to hear of your losses, especially that of your little boy. I hope Mr S has the answer you need, he is indeed a very nice man.

gransol I'm not sure if I said Hi to you but if I didn't, then Welcome!

/waves to everyone, and come on ladies, we really need some more good news on this thread! :)

I am finding all this about alternative treatments and the infection testing very interesting. If our IVF doesn't work, I think we will go down one or both of these routes.

Ladies, I'm sure people have said, but can anyone advise if Mr S has prescribed Clexane for them and if so, for what?

It's just one of Penny's (from the Serum clinic) points of advice to me was that I should be taking Clexane because of my MTHFR issue, but I asked Mr S about this a few months ago (because in the US they routinely prescribe Clexane for pregnant ladies with MTHFR issues) and he said it isn't necessary, and that he doesn't prescribe it for this. Reading back through old posts on Fertility Friends however, he did used to prescribe Clexane, so I'm confused why he now says it isn't necessary, especially since almost everyone else seems to think it is.

I know it's a bit of a moot point right now since I'm not pregnant, but Penny advised it should be taken prior to conception (her exact words were "You may need to start on clexane (at least 40mg) before you conceive to prevent early miscarriage.").

And apparently Dr Gorgy definitely prescribes Clexane prior to conception for MTHFR. Why won't Mr S then?

I remember being surprised not to get clexane from Mr S, I must have heard that clexane along with steroids was standard treatment for HNKC because I remember asking my obstetrician for this after mc3 (which she refused). It was odd seeing her again on day baby was born, I thought she might say something about my treatment but she didn't at all - it's as if they still think it's one big coincidence when you finally have a baby after 4 rmcs. (Which I suppose it could be, but I doubt it).
The mushroom medicine sounds really interesting, I do hope it pans out.

ari When I saw Mr S he said there was no need for me to be taking clexane despite having factor v leiden. However as I had already been prescribed it by my nhs consultant he said for me to stay on it. I then got tested for TEG at St Marys and was told I definitley needed to be on along with double aspirin.

ari i have the MTHFR but only hetero (I think you are homo?). Dr S also was not bothered by it, also my doc over here, who originally did the test, said it was nothign to be bothered with even if it was homo, but could be worth doing the low dose aspirin because of it (which I am up to 36 wks). I did wonder what the point of doing the test for was if it wasn't a big deal even if it was positive.

echo glad you ERPC has gone as well as it can

free your story about your antenatal class brought tears to my eyes. I had a similar moment at my classes. The teacher made some comment about us all being first timers and therefore that we had never experienced contractions before and I suddenly got a really strong memory of going through my spontaneous mcs where i had had the thought 'well this must be a bit what labour would feel like' as I experienced the waves of contractions throughout the night before it was passed out. I had to blink back the tears in the class and grit my teeth to not start blubbing everywhere. Now I am a bit concerned that labour is going to bring it all back, maybe it will a bit - like coconut experienced but I'm not going to stress about it. It's only emotions though, isn't it?

I'm really interested in hearing the infection and mushroom routes some of you are looking at.

Heartbreaking to see the lists of mcs. I didn't realise how many some of you had had and made me feel quite tearful. I feel almost a bit of a fraud being on this thread, having only had two, but they were bad enough.

Ari I asked Louise a couple of weeks ago when I got my BFP if I should be on Clexane as I have also read it is standard practice with VHNKC. She told me as I don't have antiphosphollid syndrome I dont need it - I guess that is what Mr S prescribes it for. St Marys didnt prescribe it for me either even though I had a raised TEG result but again I did not have anti-phosphollid syndrome. They did tell me to take double baby aspirin though from BFP and Mr S is happy for me to do that.