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Conception

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TTC: Pregnancy on Prednisolone or similar part 7

999 replies

ChoccyPud · 17/04/2012 13:58

A positive thread for all those diagnosed with High or Very High NK Cells and looking to start TTC or already pregnant on Prednisolone and/or Intralipid treatment.

Newcomers very much welcome!

www.mumsnet.com/Talk/conception/1419032-TTC-Pregnancy-on-Prednisolone-or-similar-part-6

Part 5 www.mumsnet.com/Talk/conception/1391787-TTC-Pregnancy-on-Prednisolone-or-similar-part-5

Part 4 www.mumsnet.com/Talk/conception/1366323-TTC-Pregnancy-on-Prednisolone-or-similar-part-4

Part 3 www.mumsnet.com/Talk/conception/1348773-TTC-pregnancy-on-Prednisolone-or-similar-part-3

Part 2 here www.mumsnet.com/Talk/conception/1323594-TTC-pregnancy-on-Prednisolone-or-similar-part-2

Part 1 here www.mumsnet.com/Talk/conception/1236324-TTC-pregnancy-on-Prednisolone-or-similar

OP posts:
eurochick · 25/04/2012 12:28

Snoopy I had a lump checked out a few years ago. Although I was only in my early 30s it was taken seriously because my mum had had pre-menopause breast cancer (the type likely to be genetic). It was scanned and all was well. I'll have everything crossed for you.

free I am also a fan of weights. It is definitely the way to get the best shape. I had a personal trainer a few years ago who got me lifting reasonably heavy weights for about 8 reps, not teeny little weights for 20 (which is what a lot of trainers do with women). After a few months I had the best body I had ever had! I still try to mix cardio and weights but I am not doing as much of either as I should be. In fact, I am not doing anything at all at the moment as the nurse at NLC said no vigorous exercise and no lifting during the 2ww. I know the advice on vigorous exercise differs but I think the lifting advice was bobbins. I always thought that pregnant women were told not to lift because of the hormones relaxing their joints, increasing the risk of straining. So it is nothing to do with conception or looking after tha baby. But I am blindly following the advice I don't believe in because if I don't, when I get AF next, I will just be wondering if it would have turned out differently if I had followed it.

Arianrhod · 25/04/2012 12:47

snoopy I'm glad you're getting it checked it, please let us know how you get on. I hope it's 'just' mastitis, or a cyst. You're absolutely right to get it checked and yes, I remember you saying about the stabbing pains. Definitely do mention the treatments you've been on to the doctor. FC for a clean bill of health.

snoopygirl · 25/04/2012 13:10

Thanks ladies.
Just called Louise at NLC to see if anyone else had a problem with Letrozole causing this and she said no and that it could just be hormonal changes of a fluid filled cyst if I have swelling. She was very helpful between me not being able to talk and sniffling over the phone! I asked her about stopping the pred and she didn't think it was necessary. I can't remember half of what she said now.

Having a full on pred day, no sleep and can't speak/get my words out.

free Sorry about delay on Hynobirthing book. I couldn't find CD but just found it so will post off to you soon as.

freelancegirl · 25/04/2012 13:18

Good call Snoopy - checking with Louise and yes it could well be hormonal. But good that you are getting it checked out. I actually have an appointment to check out a funny cut/white circle thing on my tongue after yesterday's dentist appointment, just to check out too. But of course anything like that is a bit worrying.

Euro I am so with you on the weights. Bigger and heavier the better! My workout was down to 45 minutes (if I didn't faff around) and I had the emergence of a six pack. A one pack I guess. Having lost a lot of weight when I gained three stone and lost it again after thyroid under control my tummy is never going to be taught (especially not now!) but the muscle was there and visible.

That said, I also agree with not doing too much when TTC and (now for myself) pregnant. There will be plenty of time to get in shape and it's important to be healthy but not overdoing it for TTC/pregnancy.

I've just had some devastating news from a friend of mine. Well, I say friend but we have never met. She is one of the, now close-knit, group of friends I made on here when we were all miscarrying a year ago. Most have gone on to be pregnant but not only did one have a miscarriage last week but this one has now had a comparatively late loss at 14 weeks too. Her last loss was at 6 weeks but the one before that was 20 weeks. Just awful. Fortunately she has 2 DCs already but doesn't make it any easier. She has been down every testing route except NKC so I guess that might be the next step. So with those two miscarriages and three on here in the last couple of weeks it's been a rather sad time.

GreenOlives · 25/04/2012 13:46

Hello ladies,

London So sorry to read your terrible news Sad I hope your recovery is quick and that you have lots of RL support

My lap & dye went ok yesterday. My tube is fine, they did find a small fimbrial cyst on my Right ovary but they didn't seem to think it would cause any problems. So once I'm all healed it will be back to SWI and hoping and praying for that elusive BFP so that I can see whether the Pred treatment is the answer to my TTC woes - time will tell I suppose!

There is some fascinating new info and links on here so I intend to spend my time off work having a good old read of it all!

eurochick · 25/04/2012 13:55

GO, I'm glad it went ok. Look after yourself and take it easy while you are healing.

How awful for your friend, free.

ChoccyPud · 25/04/2012 14:02

Hugs to you snoopy. Sorry you have another thing to worry about. I'm sure most of us have sobbed on the phone to Louise I know I have on more than one occasion !

Well I shall get on those weights when I feel like a trip to the gym. And braving the gym bunny men who hang out at the weights end of my gym. Oddly they all have huge upper bodies but wear tracky bottoms to cover their no doubt spindly legs :)

God I need to find some motivation. I've got awful heartburn
indigestion today, was fighting off a panic attack driving in, hardly slept last night, can't concentrate, left my papers at home (worked from home yday pm) so can't do one thing at work anyway. Just read that back. Maybe I'll go home for a break... :(

OP posts:
Coconutfeet · 25/04/2012 14:58

London ? So sorry you?re going through this again. Sad

So much sad news on this thread at the moment. Awful awful news for your friend, Free.

Snoopy ? I hope the appointment gives you some reassurance today. Let us know how you get on.

Kittens ? Crap news about your follicle as well. I really hope it?s just a one-off freak month. The whole age thing is so frustrating ? I?ve just had long conversation with a doctor about the risks associated with my maternal age and how this impacts on my delivery etc etc. Obviously I?m in a completely different position, but that whole ?at your age? thing doesn?t ease off however much we like to think we?re only as young as I feel. Grrr. I can completely understand why you?re so pissed off with the complete about turn in attitude to your age in such a short time, Ari.

Gosh there?s so much information flying around on this thread at the moment. You lot are so well-informed (through necessity, I understand). What?s so frustrating is that so much of this treatment is hit and miss. Even the hydroxy seems experimental at this stage and so it feels like a gamble, not to mention bloody expensive, to have all the the treatment.

Duggs ? It?s good to hear that you were able to enjoy some aspects of your trip at least. It sounds like a good idea to get some further tests just to rule out everything you possibly can before moving onto adoption, if there are any that you think are relevant. I think adoption is a wonderful thing to do, although I?m still hopeful for you that it won?t be necessary. I have a friend going through the adoption process at the moment following ovarian cancer and a hysterectomy. Sad Sad She said it feels quite intrusive but knows that the end results will be worth it.

Congratulations Free and Charlie on reaching the third trimester! Also, congratulations on getting the exchange date on the flat. You must feel like things are really progressing at the moment.

Good news Greenolives!

Choccy ? I?m so glad that your work are being so supportive of you at the moment.

London ? I?ve got a friend who was a strict vegetarian for years and years. She?d tried and failed to get pregnant for ages and was eventually told that she was entering premature menopause. Anyway, following several failed rounds of IVF (including one which was cancelled as they couldn?t get enough eggs), she went to a health spa in Australia where they did some kind of analysis on her body shape and diet (I can?t remember what it?s called but it?s very popular over there apparently) and told her that she was eating all the wrong foods and should be eating loads of meat and butter and drinking unpasteurised milk and various other recommendations that I can?t remember. Anyway, to my astonishment she took it all on board and now has two children conceived naturally. Obviously I have no idea whether the food thing was the key, but it is fascinating. I agree with Free though that it probably isn?t necessary to start eating meat, but more to ensure that your diet is balanced. I was veggie for years but I started to eat fish and, since I was pregnant with my ds, free range chicken. So many veggies rely on pasta and vegetables and don?t get anywhere near enough protein. As long as you?re careful abut that, you shouldn?t have to resort to meat unless you want to.

Well, I finally had an appointment with the consultant at the hospital today to discuss my delivery. They are very keen for me to have this baby by my due date rather than letting me go over (Because of my age, natch, and also because of my history of miscarriage. The placenta can work less effectively apparently). I declined a sweep today but have agreed to have one next week if nothing?s happened. They?re very keen to discuss induction then too, which I?m really keen to avoid if I can. Meanwhile, I?ve been out and bought large pineapple and told dp his luck?s in tonight! Quite frankly, this baby?s head is so far down and I?m so uncomfortable that it?s the last thing I?m interested in but he sounded pretty pleased. Wish me luck!

duggs1976 · 25/04/2012 15:37

Crikey coconut sounds interesting! Thinking of you snoopy! I had a hysteroscopy on nhs as st m thought I may have a septm uterus is ok. A day procedure. I had nothing though. Dr s does them too I believe. After investigation adoption process can only start in 6 mths (after ivf) and then 8 mths for approval then u need to be matched which can take from 2 wks to a year or more. DH and I still want to go ahead. It means I will have to consider frozen embryo transfer soon not to delay things. Thought about surrogocy options but they can take years too to find. And just as stressful and Unguaranteed as doing normal ivf. I will then try naturally each month like a normal person without medication and if I get a bfp then I can re chuck all Meds at it inc hydroxy. I have had 3 natural BFPs without Meds and a twin ivf bfp - doesn't seem to be the issue - keeping it does. Am VERY interested in those bfp onwards on the treatment - coconut, cheerful,frozen and dunnit and abney! Anyone I've missed? Might go and get some weights and peanut butter Wink

Coconutfeet · 25/04/2012 16:16

I've just re-read my post and would like to mention that that the pineapple consumption and bedroom activities are largely unrelated. I've also booked an acupuncture appointment to see if that can move things forward.

Duggs - You mention surrogacy. Do you mean to have your frozen embryo put into a surrogate, IF you could find one?

igggi · 25/04/2012 16:57

Hello, so much to read, and sorry to see more bad news London. It's almost a new month so maybe that'll be the key for things to change a bit.
The conversation about vegetarianism stood out for me, as one of about 25 years standing now. My accupuncturist was negative about this two. Accupuncture is of Chinese origin isn't it? I think vegetarianism is extremely rare in China. Also, the fact that the accupuncturist in question had seen a lot of veggie women with fertility problems may not be the causal relationship she was thinking of - let's face it, a lot of the kind of women who want to try alternative medicine are going to be the kind of women who are vegetarian!

eurochick · 25/04/2012 17:17

I was a veggie for years but started eating meat again a few years ago after developing a dairy intolerance (and briefly becoming an unwilling almost vegan). There do seem to be a lot of us on this thread. Maybe being veggie is good for the immune system or something?

london371 · 25/04/2012 17:30

Wow, it is uncanny how many veggies there are here. I think you are right Iggi, veggies are much more likely to be drawn to alternative therapies like acupuncture, so that could be the reason my acupuncturist sees the link. I hadn't thought of that.

That said, I have been veggie for 27 years and I do wonder if maybe I am missing essential stuff (... er, vague!!). I think I am going to give it a whirl. If only to build myself up more quickly than last time when I was well anaemic for ages. I can't stand meat, but intend to tempt myself with a bacon sarnie! Can't be worse that pred, right?!

snoopygirl · 25/04/2012 17:30

Been to Dr's and got examined and he (as I can feel) said that yes the lump is about 4/5cm across. No other lumps or anything anywhere, checked armpits and everything. So waiting for an appointment for breast clinic at hosp and will either have a mammagram or scan, then possibly a biopsy. I can only hope as it's come up quckly in last couple of days it's just a cyst or something. Obviously Dr's wasn't going to start guessing. So just hope appointment doesn't take too long and I can stay calm.
On the other point about food; i have been following really low carb diet this week and lost 4lb! Just couldn't let my weight get any higher. Just hope on pred I can sustain it or lose some more.

Waves to everyone, sorry no personals got Out laws here! I catch up on all the links posted later. x

london371 · 25/04/2012 18:36

Snoopy, I hope your appointment comes through soon and that it is only a cyst. x

Havingkittens · 25/04/2012 19:56

Gosh snoopy, how stressful. You poor thing. I hope it turns out to be hormonal or a cyst and that you get an appointment nice and quickly.

ari I had a Hyfosy scan at NLC which indicated there may be some scarring. They recommended I had a hysteroscopy. Louise and Mr S said that this may not be necessary in the case of Super Ovulation if I can build up my lining with progesterone supplements (which has worked), but that if I was going for IVF then I would have to have a hysteroscopy first. I have now been referred on the NHS to have one so that will be in place by the time my 6 months on SO comes to an end. Hopefully that will be intercepted by a BFP but I'm not holding my breath.

Oh, I am also a pescatarian. Not eaten meat for 26 years. The plot thickens.... Is it really a coincidence that so many of us are? I wonder? My mum was convinced this could be a factor. I don't like the thought of eating meat either.

ChoccyPud · 25/04/2012 20:02

Just to throw a quick spanner in the works I'm not a veggie though I guess I don't eat much red meat tbh. Occasional steak or lasagne or spag bol or whatever.

OP posts:
snoopygirl · 25/04/2012 20:08

docs.google.com/spreadsheet/ccc?key=0AtEN_z1FdjUMdHd6c0xCd2JRd3hXVmtTZXROYVE1OGc#gid=0

Is this the link someone was looking for?

Sorry me being on a virtual atkins diet is probably turning your stomachs!! But that rules me out of any link.

kittens & London I hope appointment is speedy too. Was a bit of a wreck in docs today. Last time I cried in front of him I miscarried on the spot and was worried I had ruined his chair!!

Hey what fun it is being a woman sometimes............

snoopygirl · 25/04/2012 20:23

kittens Sorry about your lack of follicles. I hope the Gonal F does the trick next month.

I have never heard of a Pescatarian?

Havingkittens · 25/04/2012 20:38

Pescatarian is the official term for fish eating vegetarians. Or as a friend of mine likes to call us, veg-aquarians. Which I rather like. A lot of proper vegetarians get very upset at people claiming to be veggie but eating fish so now there's a different name for each!

freelancegirl · 25/04/2012 20:55

Snoopy glad you went to the docs and I hope the next appointment will shed some light (and some positive news) on the situation.

Regarding the veggie issue - I really have my doubts about whether eating meat would result in lower nk cells but you never know - eating a huge amount of meat isn't very good for you so maybe it has a knock on effect on killing off killer cells...? Like we should all apparently smoke grass too.

To throw another spanner in the works my first two pregnancies were when I was 19 and 20 and eating plenty of meat, drinking plenty of alcohol and sampling plenty of no-quite-prescribed pharmaceuticals. And they went the same way as my second two losses, in a time of mid-30s health and fitness focused, meat-avoidance. So no direct correlation between diet, exercise and meat/non meat for me.

In terms of protein I know you can definitely get enough from non meat sources so don't worry about that.

I have had actually stick directly from Peta when someone referred to me a vegetarian on a radio show. Fish have feelings too, I think the letter explained. So I make sure I don't say I am a veggie but say I don't eat meat. Or yes, use pescatarian.

There is probably an element of 'volunteer bias' that amongst us in the same way that there might be a greater proportion of vegetarians that visit acupuncturists. Overall we are middle class (not saying our origins are but we all generally are now), there is strong bias to the south (not saying the Iggi and our more northerly sisters gorge on Haggis all day :) ), shown to be keen to research and be proactive with our health (hence why we have found a diagnosis and also found our way here...) and I am sure there will be a few more we could think of.

On the flip side, if healthy eating and exercise increased the level of natural killer cells in the body and boost the immune system maybe we should all just starting living off McDonalds :) Pass me a Big Mac and fries.

scooterchaser · 25/04/2012 23:31

Sorry to be MIA so long.

I am a bit lost for words at everything thats been happening on here, choccy, duggs, london I am so so sorry for what you're going through. It is so desperately unfair. You all sound amazingly brave and focused on next steps.

Choccy so sad to see the news about your Dad, it must be very hard missing him and grieving on so many counts. Be kind and don't expect too much of yourself at the moment, you are such a soldier carrying on and trooping back into work, it can't be easy. Have you seen Mr S again, did he take your NK levels in this pregnancy?

Duggs I can't believe you had to go through all that in the middle of Egypt on a much deserved holiday, you are made of really stern stuff and have an unbelievably resilient sense of humour! Mine would have failed me. I hope you had a restful last day out there and can come back with a serious battering of questions for Mr S.

Long long time since I posted so lovely to see that babies stogan and digi arrived safe and cuddly and really hope you much-deserving new mummies are having a lovely time, thanks for showing the rest of us the light at the end of the tunnel. Digi the photo of DS2 is gorgeous, he's a little looker.

free and charlie are you really third trim now and pq second trim, wowsers. Coconut, iggi and comedy in touching distance now! I know it won't have felt fast to you but time seems to have flown.

snoopy sorry you have had such a scare, well done for getting yourself to a doctor and hopefully it will be just one of these random things.

Interesting info on the diet and exercise front, will recap and educate myself. Where can I buy selenium, I am going to add it to my list, free did you mention to Mr S that you're on it and what did he think?

Hey to sue, kittens , ari, battery, euro, lemon, pebbles , buster, hopeful and waving hello to new friends who have joined in my very long absence from the thread! Sorry if I've missed anyone.

duggs1976 · 26/04/2012 04:12

Yay you're back scooter! R u ok? Do give an update - ttc %232 after mc on treatmemt. Is that worthy of a sub category ? Just want to keep beady eye on this list to compare treatment suggestions in case one works? free can u shed any light on hydroxy ( your wonder drug) and what it does? I know is anti malarial ? Is it expensive - could I take it without pred for example from now? What is full name- sorry can't scroll back on iPhone.
Seriously ladies without this thread I would have not come through this week. I feel like I can give it another go with dr s. Grin if Anyone fancies a spring meet up do say - sue be nice if u met free for example?

duggs1976 · 26/04/2012 04:55

Ok 5am here home day. Sitting on balcony overlooking sea.

There seem to be 14 with child or pregnant women here. With free and PQ the 2 who got Successful on second attempt with hydroxy.

That leaves 17 of us still trying. Aside from the ttc assisted and non assisted groupings we now seem to have a clear mc on treatment group.

Choccy
London
Duggs
Sue
Snoopy
Abney
Ari
Scooter
Green olives
Picolina
BellyD
Holldoll ?

11 or 12 of us with choccy top of special list..

Kittens
Euro
Pebbles
Cherry

I guess you haven't yet had a chance to know if the damn treatment works until you get a bfp, but after the struggle to get a bfp how precious is it when u hardly get them ( speaking from experience on that one ).

So pretty much everyone on this thread who isn't pregnant - all in tri 2 and 3 now so pretty normal and safe as far as immunology goes - wants to find that additional solution to the treatment. I guess dr s has all this info and more and will offer options but collectively if there is anything we come across do share.
Of course all of us want to find solution for this and presumably some pg women want another child after.
Feel driven and part of a group and not lost and alone. We WILL get there we have to.
Some dr s app on 5 and 8 may from myself and choccy so will share findings. Grin

I guess we are all individuals - however if hydroxy or some other drug starts to show success then we r excited.

lemonsherbet · 26/04/2012 06:50

scooter welcome back, what have you been up to? Anything exciting?

duggs hope you have a safe trip back to the UK.

Ari not sure if this is interesting to you but the seven seas prenatal supplement contains metafolin in it. I was planning on changing from Pregnacare, when I have finished the current packet. Have also ordered activated folate supplement to.

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