To think it will be revealed WLI cause physical aging

[Tuliptana]

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

Im really not sure how its possible to be obese at a size 12 unless you are only about 5ft tall

These women are not obese, we are friends we discuss weight etc. We are talking 11st 10 at 5ft7, bmis of 24/25 etc.

Many decades ago there was some low-level celebrity who had exactly that sort of hollow-cheeked WLI face. It was totally different to just a normal, slightly saggy face that people may get through standard weight loss or gastric band. It was the pronounced "T" shaped shadow under the cheekbone that made him look ill despite otherwise being active and normal. He later came out and admitted he was HIV positive, which explained everything. (Edit: He's still alive and fine so obviously not using someone's passing to make a point)

I feel many WLI users may be too young to remember the HIV panic in the early 90s. Ozempic face looks identical to HIV face which is possibly why many people feel instant aversion to it.

Well, here's a radical thought - maybe it will vary from person to person? Just like significant weight loss by other means, in fact...

I feel many WLI users may be too young to remember the HIV panic in the early 90s. Ozempic face looks identical to HIV face which is possibly why many people feel instant aversion to it

Yes I agree.

Kelly didn’t use weight loss injections. She had a gastric sleeve in 2018, and at some point buccal fat removal. Her recent further weight loss has exaggerated the effect of the fat removal. She has openly admitted that she is unwell due to her extreme grief. It’s about time people left her alone.

My friend who is over 60 was given WLI over 7 years ago as medication for her type 2 diabetes. She was not told it was to loose weight just informed it was a new medication.

She has lost several stones in weight and is now quite slim (and looking well) and is no longer diabetic.

Job done you would think, but her muscle loss is massive even though she is a very active woman spending hours every day gardening.

She has become quite weak lifting, digging etc and her leg muscles are very poor for ladder climbing.

I think WLI should be treated much more holistically and muscle retaining exercises given alongside the prescription.

I hadn't heard that but you are right – it's not WLI!

https://people.com/health/kelly-osbourne-gastric-sleeve-surgery-lost-85-lbs/

I really wish people would stop being blind to how many people are taking it who do not meet the criteria, and how easy it is to obtain online with minimal vetting.

I think wli are fabulous for those who need them, and should be available on the nhs easily for the truly obese. However, i do not think they should be availableto buy without in person healthchecks including weighing/measuring & proper health advice.

Many many medically useful or essential drugs are also abused by some people. Not news. Many many medically useful or essential drugs have severe side effects or adverse effects that need to be weighed up against the benefits. Not news. Have you ever heard of antipsychotics? Antidepressants? Lithium? Opiates?

Just considering antipsychotics: they have absolutely life-altering adverse effects in some people. They have irreversible and severe long-term adverse effects in some people. They have killed some people. Yet doctors prescribe them and millions of people take them. Doctors even prescribe them to people who do not consent to taking them and force them to take them. Why? Because the alternative route is even worse. So not news that potentially harmful and dangerous drugs are used to treat serious health conditions, when all risks and effects are weighed up.

Well the first thing to remember is that dress size isn't a remotely scientific measurement. Presumably you don't think M and S joggers and Primark skinny jeans are going to be exactly the same, even if they both say size 12. Lots of women are indeed 5 foot tall, but as someone who's 5 foot 2, I can assure you I did indeed have some size 12 trousers before starting WLIs and having a 31 BMI.

Also you said earlier they were barely even overweight, which means low end of overweight BMI, perhaps 26. But now it's 24. 2 BMI points is actually quite a big difference!

There is emerging evidence showing that GLP1s are actually anti aging. You are confusing saggy skin making people look older with aging.

I'm 46 lost 3.5 stone on WLI and look fucking fabulous. My face is gorgeous. my neck is wrinkly but we don't talk about that claiming that WLI users look like HIV patients is fucking ridiculous.

There is no longevity data at all. A million times one year is not a million years of data for a medication trial.

And the data that exists is for people being medically monitored, not for people who bought it from an online chemist, many by lying.

I lost almost half my body weight through diet and exercise alone (still trying to shift a bit.) It aged me significantly. Your skin just can't snap back into place once it's been stretched to a certain point. I'm actually quite itchy all the time because it's harder for the body to hydrate loose skin.

It's all worth it, but weight loss isn't utopia. I have health and cosmetic concerns that a person who has always been thin would not.

YANBU - it’s known that the injections cause muscle wastage as well as fat loss. I think that’s why Kelly looks so bad, she’s also lost muscle tone off her face as well as padding.

This happens when you lose a lot of weight no matter how you do it. Remember the Catherine Deneuve: At a certain age you have to choose between your face and your ass!

@Suzyfandango I do agree with you there. My brother in the US has to have regular blood tests on WLI. I am in Ireland and I don't, but I do a full heath check battery of at-home blood tests myself every 6 months anyway.

Agreed - but then i think all these drugs should be minimised. We don't want to end up like America where the pharma marketing machine is well and truly embedded and its easy to get things like anti depressants etc.

Medicine should be about health. The NHS should be working in partnership with local councils on exercise initiatives etc.

Exactly

Yes people do look older but they look 100% better being a healthy weight. Who wants to be wrinkle free but fat and unhappy?

What do you mean by holistic? We could tell people to exercise, but that doesn't really mean much because people can already do it anyway. Some of us even did before starting! And it won't target the illicit users who are going to be the biggest risk.

Well she wasn't prescribed it for weight loss was she? It wasn't some kind of secret trick. It was a diabetes medication before a weight loss one. She's still better off if her diabetes is in remission even with muscle loss. When you have a serious disease everything is a trade off.

Initially it was gastric sleeve- that doesn't mean she didn't use wli afterwards 2019-2026. You don't get this cadaveric look on a healthy diet even if you're slim.

Yes but you can't obtain opiates or anti psychotics online after a 2 minute questionnaire. You need a prescription from a doctor.