To think it will be revealed WLI cause physical aging

[Tuliptana]

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

Well think about it. The drugs in their current form result in accelerated muscle wastage.

You can work out at the gym. But there are many smaller supporting muscles that it is harder to work out. They are affected too.

Whilst people do tend to look drawn and thin when they lose a lot of weight, the muscle wastage whilst using WL drugs is more profound, because not only are you losing a lot of weight quickly, but there is a compounded side effect of muscle wastage from the drug itself on top.

But as with EVERY interventionist medication it's choose your poison. Either this..or that.

I know someone who had severe depression with episodes of psychosis. Repeatedly sectioned. One drug was found to significantly alleviate his symptoms. The side effect it gave him was diabetes. He preferred to live with the diabetes.

I take a massive ton of drugs for several autoimmune conditions and cannot sometimes remember my own name. I worry about early dementia and there are studies showing a possible increased risk with taking this drug, plus a couple relatives do have dementia in my family. I am taking the risk over the short term daily hell of my other symptoms.

So I see no need to worry about it it regards to other people's choices. Sometimes you have to decide what the biggest risks to your health are.

Comparisons with patients dying of aids just shows so much about the poster. I'm shocked that they even thought it much less typed it.

This is absolute rubbish. Theres no difference in terms of using WLI to lose weight as to how the weight loss makes you look. Both these women being discussed look the way they do in terms of their faces due to facial surgery, they have literally had fat taken out of their cheeks. Same with many other celebs.

Forgetting celebrities, many people at work are using them (nurses) and they all look so much healthier than they did because they had been obese for a long time, but their faces have changed a lot. They’re all 50s and 60s so their ages are showing more than when their faces were fuller. It’s the impact of weightloss rather than WLIs.

Those scoffing at people using them when “only 2 stone overweight” - at just under 2 stone overweight I classed as obese and met the criteria to use them. I was a size 14. Obese isn’t as big as you think (I was shocked).

There’s plenty of information available about the effects of WLI on aging (positive) so you could read them to understand the reality.

Or you could base your “theories” on a gut reaction to your feelings when you see the face of someone who has had huge amounts of cosmetic surgery.

Personally, I think a scientific approach is more likely to reveal the truth.

https://www.telegraph.co.uk/news/2025/05/13/nhs-weight-loss-jabs-set-to-make-britons-live-longer/

“Britons not deemed obese could soon use weight-loss jabs to live longer”

To flip it around, obesity causes significant ‘unseen’ physical ageing to your internal organs, that puts you at risk of an earlier death. I think any external, cosmetic ageing is preferable to that! Plus people who’ve had extensive facial plastic surgery (and likely buccal fat removal) and then lost weight because of WLI, plus grieving, are outliers.

Of course it would, only got to look at pictures of very overweight people from the past before WLI came along to see that, Nigel Lawson, Nicholas Soames etc spring to mind, unrecognisable once they had lost weight but much healthier for it.

I lost 6 stone by dieting about 5 years ago. Got Ozempic face. No GLP1 existed then.

However, my cholesterol dropped, my blood pressure went back to normal and I reversed my pre-diabetic status.

A bit of Ozempic face / visually ageing 10 years is well worth the massive health benefits of weight loss.

And yes, I have used GLP1 since putting a little of the weight back on. Yes, I'm back to having a saggy face. My insides are healthy though! GP approved.

Pretty sure the OP is a bitter slim person that hates that they can no longer feel superior to fatties and is hoping that all us previous fatties suffer for the ease of WLI now.

Agree

Nobody ever died of looking a bit older, but many have died from complications of obesity.

My mum looks absolutely ancient - incredibly deep wrinkles.

Except it's caused by her lifelong eating disorder.

I know KO has confirmed had bariatric surgery, i think she has denied she has taken glp 1 medication .
Facial fat loss seen in extreme rapid weight loss(for any reason) and skin laxicity does seem ageing though.
glp 1s were used for type 2 diabetes for a long time,im wondering if any studies were done on the effects with longer term use in that group?

I agree. The term 'Ozempic Face' could just as easily be called Weight Loss Face. It's not Ozempic or other WLI specific. It's just that the huge prevalance of examples of it at the moment are largely due to the popularity of WLI.

Also agree that the women who can afford it, the women who are photographed a lot because of who they are, will have cosmetic surgery to deal with slackened facial skin and with a certain type of woman there is no such thing as 'less is more.' They will go full-on in the belief that you cannot look too thin or too taut. It's the same with implants of any sort. They opposite happens and they go large. They don't want subtle, they want extreme. It's not a look I like but it's popular among certain types.

Does it not occur to you that the medical profession MIGHT have cottoned on to this?

As opposed to some internet random being able to supersede the health experts (who hail it as revolutionary) and know something they don't? The arrogance is mad.

Rich unhappy people do what they have always done which is to try and buy happiness. Only all they end up with is an expensive form of misery.

It doesnt really matter if it is prescription WLI or prescription painkillers. They have the budget but no sense so they look to buy a quick fix.

The vast majority of people on WLI are using them to solve a very real problem. Where they are having to pay for it themselves they are taking as little as possible to keep the cost down.

Quite. I think a lot of people’s mental image of ‘obesity’ is of someone very large. Whereas in BMI terms, the difference between the upper end of a healthy BMI and lower end of an obese one isn’t much more than 2 stone. At 5’2” it’s the difference between being 9.10lb and 11.10lb.

You are just embarrassing yourself now OP.

@Tuliptana women who carry alot of extra weight you will find look younger . They are filled out by fat when the cologne goes .
it’s only when/if they loose weight they start to age .

Pharmacies are part of the NHS?

I get it on a private prescription which is entirely separate to the mhs functions it operates. Pharmacies are private businesses with nhs contracts.

In this century, we have lost touch entirely with what a genuinely healthy weight looks like.

Basically this.

It's also quite touchingly naive of that poster to think the NHS is going to do a better job at monitoring than the private prescribers are currently offering.

Have you criticise with no idea what support a GP has to give someone on GLPs? From what I've read, it's a lot. Has your pharmacist sent you to a dietician? (I have no experience of it, just what I've read)

@PurpleCoo if you are looking lean and defined, then you need to stop the WLI, if you haven’t already.