I've read many of the comments on this thread, but wanted to wade in with my personal experience.
We spent 6 years in the US (south west Ohio). The first two, we were new grads; the four years, DH was on a very swanky international contract (nominally 3x his UK salary, when all the bonuses were added in).
I would say that on both stints, we weren't any better off there than here. Some things are more expensive, other things are cheaper. It really is swings and roundabouts. We didn't let money burn a hole in our pockets - our trips were very modest as we had five kids and going away was a military operation. What I do remember is that our trip to Cape Cod was eye-wateringly expensive. Apparently, the labour costs there are high, so the costs get passed on.
One of the weird things about living in the US, is that you pretty much live among people of similar status. That will dictate where you actually live rather than what you can afford on paper. We actually did choose a lower ranked house than DH's colleagues as we felt that was better for our kids. We certainly weren't going to rent a McMansion 30 miles from downtown that we would not have wanted to fully furnish (due to returning to our house in the UK four years later).
I liked a lot of what we had in the US, although a lot of it was being part of an expat community. Saying that, our neighbours were really friendly, and one had the right amount of cynicism and got my jokes. I liked the real weather - snow in the winter, beautiful autumn colours, hot summers (although a bit too humid). Spring was probably the worst because the weather couldn't make up its mind.
The worst part was the very real racism (although we are both celtic white). My son invited his school friend over one Saturday - he was black - his dad said this was the first playdate he had ever had at 10 years old. My son played in a black football team. When I suggested to a neighbour at having the team and their mums over for tea, I was told not to - they would steal from me! I wasn't happy when my neighbours said they had guns - my kids never went to their house again.
Another thing is the distance that you drive for day to day stuff, and the absolute need to drive. I hardly ever use my car here in the UK as everything is on my doorstep, and there are buses and trains.
In my US neighbourhood, very few people had their own pools. They could afford them, but we had a very good private pool club where we would hang out all day every day. The kids had their swimming lessons and then played, and the mums chatted.
What makes me happy is that my eldest (now 33) really cherished his time in the US (3rd - 6th grade) He has good memories and when he has gone back as an adult, he was researched his trips and really made the most of them. He got married this year, and had a quiz at his wedding. One of the sections was about Cincinnati - so I think that's a good sign.
My DH is about to renounce his US citizenship.