In all honesty OP, I think you're asking in the wrong place.
If I were you I would sound out some of your actual friends and family, the people who you would really want to be there, and ask them to tell you honestly whether they'd be up for it or whether it would just be a major pain in the arse.
I got married in France, OK it wasn't a destination wedding because my husband is french and we live here, but nearly all of my friends and family from the UK came.
Two close friends of mine in the UK got married in France and Italy respectively. In each case one of the couple was from there, but lots of people travelled from the UK.
My friend's sister had a destination wedding in Spain, no connection to the place whatsoever, she just wanted to, and I think it was well attended and people had fun.
It really depends on what kind of friends and family you have. Mumsnet is very negative about this sort of thing but not everyone is.
If you are going to do it, I would highly recommend doing it somewhere close to an airport with regular cheap flights from the part of the UK most of your friends and family would be travelling from. Paying for accommodation is lovely but also consider how they're going to get there. If it's a 100€ Uber ride from the airport then that's not so great. Both my friends laid on coaches after their weddings to take people from the venue back to where they were staying.