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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

See all MNHQ comments on this thread

to think more negative effects will come out from Ozempic use?

692 replies

nameey · 22/02/2025 11:12

Just read that the 30 year old singer Avery has been diagnosed with osteoporosis due to Ozempic use. Looks like this could be the start of many conditions coming out.

I know Ozempic is incredibly helpful for a lot of people but losing weight but then having osteoporosis does not seem worth it.

AIBU?

OP posts:
soupyspoon · 22/02/2025 17:27

BeardofHagrid · 22/02/2025 17:22

Someone told me ages ago that it will cause an epidemic of pancreatic cancer. Seriously messing around with your anatomy is never worth it imo.

You're right, what are the epidemics likely to be caused by layering flab upon chub upon flab upon chub. Particularly around the midsection? Is there any information about the health issues caused by that?

Glorybox2025 · 22/02/2025 17:28

BeardofHagrid · 22/02/2025 17:22

Someone told me ages ago that it will cause an epidemic of pancreatic cancer. Seriously messing around with your anatomy is never worth it imo.

Oh well if someone told you...

GLP-1 medication doesn't 'seriously mess with your anatomy'. It is also hardly your business to decide what's 'worth it' to other people who aren't you!

Tulipsandaffodils · 22/02/2025 17:29

nameey · 22/02/2025 17:10

https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/

One year after withdrawal of once‐weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two‐thirds of their prior weight loss, with similar changes in cardiometabolic variables.

I’m staying on mounjaro for ever, a low dose, I feel awesome, all health markers improved, off my bp meds, a healthy weight again, blood sugars controlled, insulin well managed. I also eat my protein and work out, cardio/strengrh at least 5 days a week.

id not take much store by someone with an eating disorder who developed osteoporosis, it is the risk she sadly ran with her eating disorder.

but no one has to take it. You don’t need to op. Curious. Do you worry about other meds? Or just weight loss 😂

MJMaude · 22/02/2025 17:29

soupyspoon · 22/02/2025 17:27

You're right, what are the epidemics likely to be caused by layering flab upon chub upon flab upon chub. Particularly around the midsection? Is there any information about the health issues caused by that?

Someone once told me that's just fine, so don't worry about it @soupyspoon!

Tulipsandaffodils · 22/02/2025 17:31

There is a thread like this every few days, where is the poster with the bingo card.

I reckon it’s a small handful of obsessives name changing and repeatedly doing it as they can’t get the drugs or resent them.

Twiglets1 · 22/02/2025 17:32

SwingTheMonkey · 22/02/2025 17:13

You’d have to have type 2 diabetes to be prescribed ozempic if you’re in the UK. It’s not licensed for weight loss alone.

It would decimate the weight loss industry if people could be on WLI long term. Which is one of the reasons there is a constant stream of negative press about them.

I got it from a private pharmacy in the UK for weight loss. I’m not diabetic.

soupyspoon · 22/02/2025 17:32

MJMaude · 22/02/2025 17:29

Someone once told me that's just fine, so don't worry about it @soupyspoon!

Oh brilliant

reaches for more chocolate

KrankyKumquat · 22/02/2025 17:37

@BeardofHagrid
Do you feel that way about all medications? Or are you lucky enough to be so healthy you're not faced with the dilemma of having to weigh up the benefits and potential costs of a prescribed medication? (btw, do you have to pay for your own life-saving medication yourself because the NHS won't?)
Is this 'someone' involved in medical research? I hope they share their findings as there's an awful lot of T2D, who've been taking glps for years, who'd like to hear what they've discovered.

Sampler · 22/02/2025 17:39

“Someone told me ages ago”

you need to quantify ‘ages ago’ and the medical credentials of said person before you type such things, anyone can say anything given your rather loose criteria.

I think the singer in question has had an eating disorder for years - she would have got osteoporosis from that. I won’t read it as it’s the daily mail and they had another story recently that turned out to be shite as well.

gingercat02 · 22/02/2025 17:42

Seems unlikely. GLP1 RA have been used as a treatment for type 2 diabetes for 20 years with few issues.
It's idiots using it off license that are going to come to harm

ZenNudist · 22/02/2025 17:42

StMarie4me · 22/02/2025 12:49

@Nowvoyager99 because that's literally what this thread is about?

I could also mention the 50 or 60 cocaine deals a day that used to take place across the road from me, many of whom were 30-50 year old smartly dressed women and men.

Or the women in the 90s in the Hampshire village I lived in who all drank Diet Coke in the pub and snorted coke in the toilets to stay thin.

Happy now?

To be fair thst sounds like they were doing it to have fun and staying thin was a side effect...

0ohLarLar · 22/02/2025 17:51

People talking about online pharmacies requiring videos of you stepping on scales etc...

All this sort of thing is easy to fake. Unless you are naked you can hide weights in clothing, or send a video of a friend, or tamper with your scales. Thus why plenty of people are accessing it who are neither diabetic nor obese.

It should be illegal to prescribe it unless you are seen face to face & your weight/bmi checked in person, including for follow ups. The research is not there to demonstrate that the pros outweigh the potential side effects unless you are actually obese.

PinkArt · 22/02/2025 17:52

Matrixremooted · 22/02/2025 11:54

I agree to an extent OP and it will be interesting to see what the data says over the next few years, but those who are taking WLI do not want to hear anything negative at all about them. As far as they’re concerned they are the golden panacea for their weight issues.

I'm always very open to hearing about the negatives as I want to make sure I'm fully informed about the potential side effects of any meds I take. YOU'RE ALL GOING TO GET OSTEOPOROSIS, FATTIES isn't anything to do with helpful discussion about WLI though.
As others have informed the OP, Avery had an eating disorder and didn't get it through a reputable medical supplier. That has as much to do with those of us taking it as it should be used as Matthew Perry's painkiller addiction does any of us using ibuprofen.
I would love if the two conversations could be kept completely separate in the press in future. If there is an increase in deaths or serious side effects from people taking it as prescribed then fuck yeah I want to hear about that. But people abusing it like Avery did has absolutely nothing to do with that.

1clavdivs · 22/02/2025 17:53

If we're talking about a sample size of one, here is the difference WLIs have made to my bone density (and muscle mass) since I started them.

to think more negative effects will come out from Ozempic use?
BigHeadBertha · 22/02/2025 17:54

I am currently on Rybelsus (oral Ozempic) for diabetes, not weight loss. It was originally prescribed to regulate blood sugar in diabetics. I am not overweight. However, getting from "normal" to "thin but not too thin" could definitely help me to possibly be able to get my blood sugar back into normal range and go off all drugs. So I am hoping to only be on these meds for a couple more months, six months total.

That said, yes I do wonder what might come out about Ozempic and the other semaglutide drugs in the future, especially when they're used long term. (For diabetes, I believe the usual expectation is to be on them forever, though I don't plan to do that myself. If the weight loss isn't enough to correct my blood sugar, then I will switch to one of the old tried-and-true meds diabetes meds).

Now they're saying Ozempic also greatly helps with alcoholism. It really does seem to be touted as a "wonder drug." However, as far as I know, the long term effects simply are not yet known.

BeardofHagrid · 22/02/2025 17:54

KrankyKumquat · 22/02/2025 17:37

@BeardofHagrid
Do you feel that way about all medications? Or are you lucky enough to be so healthy you're not faced with the dilemma of having to weigh up the benefits and potential costs of a prescribed medication? (btw, do you have to pay for your own life-saving medication yourself because the NHS won't?)
Is this 'someone' involved in medical research? I hope they share their findings as there's an awful lot of T2D, who've been taking glps for years, who'd like to hear what they've discovered.

What?

BettyBardMacDonald · 22/02/2025 17:54

One of my friends is a lifelong endocrinologist and internationally known obesity/diabetes researcher. He says that these drugs are very safe and have been in use for a long time. Decades.

My sister has stage 4 cancer and her oncologist, also an esteemed physician researcher, has no problem with her patients taking Ozempic. The benefits of lower weight to cancer patients are well known.

BellaCiao23 · 22/02/2025 17:59

Orangesandlemons77 · 22/02/2025 17:22

"admitted she took the weight-loss drug after struggling with an eating disorder."

Eating disorders aren’t rare, although they are rarely diagnosed unless someone is a six-stone anorexic. There are conflicting interests between the weight loss industry and the online sites selling weight loss pens.

StMarie4me · 22/02/2025 18:01

@Glorybox2025 I'm not a scientist so I don't know... that being the point.

BellaCiao23 · 22/02/2025 18:02

BettyBardMacDonald · 22/02/2025 17:54

One of my friends is a lifelong endocrinologist and internationally known obesity/diabetes researcher. He says that these drugs are very safe and have been in use for a long time. Decades.

My sister has stage 4 cancer and her oncologist, also an esteemed physician researcher, has no problem with her patients taking Ozempic. The benefits of lower weight to cancer patients are well known.

That’s interesting. I was a size 8-10 when I was diagnosed with cancer and was prescribed weight gain supplements. I was probably BMI 19-20 so within the normal range. I also researched the Dutch Hunger Winter and there was a spike in breast cancer cases in women after that.

StMarie4me · 22/02/2025 18:05

@BettyBardMacDonald apart from those cancer patients who have died because were too ill/ thin to withstand surgery etc. what a rude and uninformed statement.

KrankyKumquat · 22/02/2025 18:07

BeardofHagrid · 22/02/2025 17:54

What?

What don't you understand? Or have you reached the limit of your critical reasoning skills?

hehehesorry · 22/02/2025 18:08

It's their own fault if there are negative effects, mainly if you're taking it when not obese just to shift some extra pounds. I understand very overweight people using it to avoid death or other horrible things but if you're just fat then eat less. I like food too much to contemplate using it, I binge for a few months then go back to fasting if my clothes start getting tight. The idea of food seeming shit is horrible to me.

Tulipsandaffodils · 22/02/2025 18:08

BettyBardMacDonald · 22/02/2025 17:54

One of my friends is a lifelong endocrinologist and internationally known obesity/diabetes researcher. He says that these drugs are very safe and have been in use for a long time. Decades.

My sister has stage 4 cancer and her oncologist, also an esteemed physician researcher, has no problem with her patients taking Ozempic. The benefits of lower weight to cancer patients are well known.

My gp said the same, and the findings in the initial trials, decades ago, of pancreatic cancer etc they then tweaked the drugs, and that’s why we aren’t seeing it. But they have to put it on the box.

TheBeautifulSausage · 22/02/2025 18:08

Tulipsandaffodils · 22/02/2025 17:31

There is a thread like this every few days, where is the poster with the bingo card.

I reckon it’s a small handful of obsessives name changing and repeatedly doing it as they can’t get the drugs or resent them.

It's something like that, yup.

I'll tell for sure what is NEVER behind them: genuine concern.