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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

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to think more negative effects will come out from Ozempic use?

692 replies

nameey · 22/02/2025 11:12

Just read that the 30 year old singer Avery has been diagnosed with osteoporosis due to Ozempic use. Looks like this could be the start of many conditions coming out.

I know Ozempic is incredibly helpful for a lot of people but losing weight but then having osteoporosis does not seem worth it.

AIBU?

OP posts:
StMarie4me · 22/02/2025 12:54

MrsTWH · 22/02/2025 12:53

These drugs have been used for around 20 years for diabetics, so they do know what long term effects are.

If you take the drug, it needs to be properly prescribed by a doctor and you need to meet the criteria for it. If you don’t and you lie about it or buy it online off some random, then yes you’re likely to FA & FO.

They aren’t a magic pill, you still need to do the healthy diet and exercise - it just makes it easier to do long term. Fat people are abused for being fat, but abused for losing weight the “wrong” way. Ridiculous.

I have reversed my high cholesterol, pre-diabetes, indicators of NA-Fatty Liver disease have gone. There are side effects, sure, but longer term health benefits are worth it for me. Others might feel differently.

They do- for diabetics. Not for non diabetics.

MiserableMrsMopp · 22/02/2025 12:56

Lots of very commonly used drugs have long term effects. Paracetamol and ibuprofen which are very easily bought over the counter can damage kidneys, cause internal bleeding and interfere with inflammation which is part of the body's healing process.

Aspirin causes stomach bleeding and ulcers.

Decongestants can cause raised blood pressure (which is known as the silent killer).

Any drug will have bad side effects. Ozempic is no different.

Nowvoyager99 · 22/02/2025 12:57

IesuGrist1975 · 22/02/2025 12:50

Perhaps but for those it was actually intended to help, those living with T2D and obesity, I believe the risks are less problematic than those of the existing disease.

The issues arise when people who do not really need to be using GLP-1 agonists use them- the fact someone with a ED can get hold of them so easily is appalling and a failure of the medical/ pharmaceutical systems in place.

I agree. But you know you can order Valium, dihydrocodeine, all kinds of stuff on the internet now and take it without medical supervision.

For some reason that doesn’t bother too many people, but women taking Ozempic in the same way seems to provoke quite a nasty reaction.

This woman, no idea who she is, has got a bloody cheek complaining about the osteoporosis diagnosis she has. Utterly stupid. But no more so than anyone taking other drugs incorrectly.

Delatron · 22/02/2025 12:58

I think part of the issue is that you not only lose body fat but also muscle mass. Strong muscles = strong bones.

So weight training and adequate protein (which I doubt is happening) is important when ion these drugs. Especially for middle aged women.

Glorybox2025 · 22/02/2025 13:05

StMarie4me · 22/02/2025 12:54

They do- for diabetics. Not for non diabetics.

Do you think the risks are materially different for people with and without diabetes?

Glorybox2025 · 22/02/2025 13:06

Delatron · 22/02/2025 12:58

I think part of the issue is that you not only lose body fat but also muscle mass. Strong muscles = strong bones.

So weight training and adequate protein (which I doubt is happening) is important when ion these drugs. Especially for middle aged women.

Who do you doubt is weight training and eating sufficient protein on these drugs?

mindutopia · 22/02/2025 13:09

Yes, it will be an issue a few years down the road. No pharmaceutical is without side effects and some of them quite serious (I say this as someone who HAS to take meds for a life threatening condition). For people who need to lose significant weight to be healthy because their weight is significantly impacting their health and long term survival, the benefits will outweigh the risks. It will be life changing.

For everyone buying it from some dodgy online pharmacy who just has food issues and wants to be skinnier than Sharon on the school run, the risks likely long term will outweigh the benefits. And that’s before you get to everyone just gaining the weight back and more when they stop. I think we will see a backlash in a few years time and lots of people saying “but if only I knew about…”.

takehimjolene · 22/02/2025 13:46

I agree that we're likely to see more cases over the next few years of serious side effects etc in people who take this sort of medication without proper medical supervision and/or when they don't really need it. Just as we would if lots of people suddenly started taking other prescription medication without medical advice.

However, as I do think there are some people who don't like the idea of overweight people having what they see as an easy option. I am not large enough to take weight loss injections but I am overweight and go to a weight loss group to try to get to a healthy weight. I have been surprised at some of the negative comments I've had from slimmer people about joining this group instead of 'just' eating less and moving more. Other members tell me they've experienced similar, including people who have been obese and have got to a healthy weight.

myplace · 22/02/2025 13:50

I desperately hope that it can be safely used. I’m trying hard to keep off the 5 stone I lost on SW but it’s creeping back on. I’m only hoping by the time I’m back unmanageable again It’ll be available on NHS.

XWKD · 22/02/2025 13:52

If you starve yourself you get osteoporosis. Ozempic isn't the cause if prescribed and used appropriately.

MigGril · 22/02/2025 13:55

MrsTWH · 22/02/2025 12:53

These drugs have been used for around 20 years for diabetics, so they do know what long term effects are.

If you take the drug, it needs to be properly prescribed by a doctor and you need to meet the criteria for it. If you don’t and you lie about it or buy it online off some random, then yes you’re likely to FA & FO.

They aren’t a magic pill, you still need to do the healthy diet and exercise - it just makes it easier to do long term. Fat people are abused for being fat, but abused for losing weight the “wrong” way. Ridiculous.

I have reversed my high cholesterol, pre-diabetes, indicators of NA-Fatty Liver disease have gone. There are side effects, sure, but longer term health benefits are worth it for me. Others might feel differently.

The dose for diabetes is a lot lower though. Drugs can cause more issues at higher doses.

I don't have a problem for people using them if they are clinicly obese. I think it can be a very helpful tool, but the way people can currently accessing it is the issue. There needs to be more medical oversite.

I watched an interesting YouTube video from a Doctor in the US who has been using these drugs for a number of years already. She said you really need to do resistance training when using them in order to not end up with muscle and bone issue due to the rapid weight loss.

BellaCiao23 · 22/02/2025 13:55

I’m not diabetic and don’t have a BMI high enough to be prescribed these medications but I do think more side effects and long term effects are emerging. Just the thought of nausea puts me off - had enough of that with pregnancy sickness and chemotherapy. I would like a magic wand to make me a size 10 though.

Lampzade · 22/02/2025 14:33

.
Tbh, I am fed up of all those who continue to focus on everything negative about the weight loss injections .
All prescription drugs can have side effects .
I once took a prescription painkiller for severe period pains and ended up in hospital.
Anyone who misuses or takes prescription drugs which doesn’t agree with them will have an adverse reaction.
Envy and jealousy is at the root of this negativity and there isn’t anything that is going to convince me otherwise .

Sinkintotheswamp · 22/02/2025 14:39

I assume she'd already caused the osteoporosis by having an eating disorder. If she'd restricted milk and cheese since she was a teen her bones would have already been weak.

ANiceBigCupOfTea · 22/02/2025 14:40

Any kind of drug is all risk v benefit.
The issue isn't people using ozempic, it's people lying on the forms and the ease of doing so for online pharmaceuticals.
I have 2 friends taking ozempic. One is doing amazing, has lost 3 + stone and is using his success to build up good sustainable habits like going to the gym and eating well.
The other has had an eating disorder and while she's lost weight, she's not changing her habits.
I think its clear for weight management it should only be a short term drug to give people a good head start at weight loss while they slowly build up the good habits to keep it off and transform their health.

Lampzade · 22/02/2025 14:40

Long term use of Ibuprofen and prescription steroids can also lead to blindness..

Nowvoyager99 · 22/02/2025 14:42

Reading the Daily Mail can lead to blindness.

Or complete and utter stupidity…

naemates · 22/02/2025 14:43

I'm kind of okay with people who lie to get drugs having a bad time because of it. Being responsible for your actions used to be a thing

Donotgogentle · 22/02/2025 14:46

MrsTWH · 22/02/2025 12:53

These drugs have been used for around 20 years for diabetics, so they do know what long term effects are.

If you take the drug, it needs to be properly prescribed by a doctor and you need to meet the criteria for it. If you don’t and you lie about it or buy it online off some random, then yes you’re likely to FA & FO.

They aren’t a magic pill, you still need to do the healthy diet and exercise - it just makes it easier to do long term. Fat people are abused for being fat, but abused for losing weight the “wrong” way. Ridiculous.

I have reversed my high cholesterol, pre-diabetes, indicators of NA-Fatty Liver disease have gone. There are side effects, sure, but longer term health benefits are worth it for me. Others might feel differently.

Congratulations, that’s a really huge health gain.

TheWickerWoman · 22/02/2025 14:47

Lampzade · 22/02/2025 14:33

.
Tbh, I am fed up of all those who continue to focus on everything negative about the weight loss injections .
All prescription drugs can have side effects .
I once took a prescription painkiller for severe period pains and ended up in hospital.
Anyone who misuses or takes prescription drugs which doesn’t agree with them will have an adverse reaction.
Envy and jealousy is at the root of this negativity and there isn’t anything that is going to convince me otherwise .

Exactly what I wanted to say.

I’ve been prescribed Mounjaro through my GP because I fit criteria and am being properly monitored.. When I was telling my boss; she was horrified and went straight to ‘why don’t you come to slimming world with us’ and went off to reel a lot of negative stories (which usually come from people who have misused it) She then went on to tell me I will just pile it all back on once I finish.. (doesn’t that happen with all diets?).

I have noticed that people delight in telling you the bad side of it but not the positive.

Don’t get me wrong, I know there can be side effects and some people will suffer negative reactions but that risk comes with all prescription medication.

she also called it a ‘quick fix’ which it isn’t. I will be on it for a while and have completely overhauled my eating habits because I want to do it right and continue a healthy lifestyle once it is done. It’s not all just eat what you want and jab yourself at all. It’s a complete lifestyle change - if you are going to do it properly.

Delatron · 22/02/2025 14:48

Glorybox2025 · 22/02/2025 13:06

Who do you doubt is weight training and eating sufficient protein on these drugs?

I thought the drugs affected hunger? So you’re eating less. It’s hard to get enough protein when you’re eating 3 meals but when you’re eating far less than that I can imagine it would be tricky.

Donotgogentle · 22/02/2025 14:58

I think the opposite OP. The anti- inflammatory effect may well mean a lot more of us take these drugs in the future, not to deal with obesity:-

https://www.theguardian.com/society/2025/jan/20/weight-loss-jabs-linked-to-reduced-risk-of-42-conditions-including-dementia

I do feel there can be a rush to lose weight very quickly on weight loss injections which does worry me. I’m on Mounjaro and aiming for 1-2lb a week.

DancingLions · 22/02/2025 15:11

Shame a pp used a daily fail link, but the blindness thing is the reason I wouldn't use it. (There's been a lot written about it).

Every medication I've ever had, I've always got at least one supposedly rare side effect. So I just couldn't risk it personally. I'm sure millions of people can use it and be fine but I wouldn't feel confident, knowing how I am.

unsync · 22/02/2025 15:18

Pass the bingo card please.