to think more negative effects will come out from Ozempic use?

[nameey]

Just read that the 30 year old singer Avery has been diagnosed with osteoporosis due to Ozempic use. Looks like this could be the start of many conditions coming out.

I know Ozempic is incredibly helpful for a lot of people but losing weight but then having osteoporosis does not seem worth it.

AIBU?

The link about people going BLIND.... it's a possible small increase in the risk of an extremely rare eye condition, which is actually caused by a sudden drop in blood sugar not by the medication itself. So a possible risk to the people who are susceptible to it of any kind of calorie restricted diet, or short term period of not eating.

I guess having been on Mounjaro for 7 months that if I was going to go BLIND it might have happened by now!

That's a lot of assumptions.

I worry about the effects too. I have a niece in law/ step son and daughter in law all taking it and they are young with very young children. They were “heavy” but not obese but I can see how much better than feel being thinner. I have seen phen phen then alle’ in my lifetime and phen phen in particular caused serious cardiac issues. We won’t know until there are longevity studies completed. I worry most about gastroparesis which is very very difficult to cure. I would like to see It be successful. I have young obese patients and I can see all their future health and emotional problems already starting. Weight loss is life changing but science has yet to prove a safe way to do it and maintain it but it’s possible ozempic is it.

I do think there are long term implications with WLI that we aren’t quite addressing properly BUT the problems aren’t the drug - it’s people who are using the drug when they shouldn’t be.

I think there will be issues but due to the drugs being misused eg:

• people lying about weight to get it prescribed for longer
• people extracting the 'golden dose' and doing this incorrectly, not administering properly or other associated issues eg hygiene, injecting too deeply (not possible with the proper pen injection)
• side effects causes by people eating crap and potentially causing greater issues
• buying dodgy semaglutide etc from non registered prescribers

All the above I have come across in online forums

I think if it is followed correctly the negative effects will be minimal

Well there are plenty of people abusing the drug (lots of posts all over the internet with people making up their own rules and doses instead of taking it as prescribed) but it’s also going to cut obesity rates massively and improve a lot of people’s health

It's been really good for me.

So @nameey did you even read the article? I'm guessing not and you just wanted to stir anti weight loss jabs eh?

9 out of 37 million....

But American doctors, who tracked more than 37million people, said the injections put users at higher risk of nonarteritic ischemic anterior optic neuropathy (NAION).

However, overall risk of developing the condition while on the jabs remained 'low', experts said.

The medics cautioned that further research was still vital to further prove the link and said they couldn't be sure why the medicines, collectively known as GLP-1 agonists, may trigger the condition.

It comes as separate research released last month detailed nine cases of US patients who went blind after taking semaglutide or tirzepatide, the active ingredient behind Mounjaro, another popular weight-loss jab.

"I want to make it clear that I do have an eating disorder and did NOT get Ozempic from a doctor."

I am pretty sure I could also make myself very unwell by illegally obtaining drugs I do not meet the qualifying criteria for. This is not a warning case against Ozempic, it's a warning case about being an irresponsible idiot and misusing licenced drugs.

I listened to a doctor who said we will start seeing some of the rarer serious side effects with Ozempic and similar, mainly because more people are taking them.

If there is a 1 in 100,000 chance of x side effect, the more people take it means the more cases of the rare side effect you will see.

It doesn't mean the drug is more dangerous that it was before, it's pure statistics.

A huge issue at the moment is the control of the drug and stopping people taking it who shouldn't be.

Agree! It's v weird. I guess they can't think themselves superior for being slim anymore, if everyone is slim

My cardiologist was very impressed with my mj weight loss

We'll see more and more of these cases its simple stats. Million to one chances happen more than 60 times a day in the UK - simply because of the # of poeple.

I agree to an extent because these drugs haven't been tested much on people who are merely overweight not obese or diabetic, yet people are using them who really shouldn't be based on clinical need. Also, some users are saying they intend to follow a "maintenance dose" for life and the long term effects of continuing to take it when you're no longer obese and for so long have not been studied. The NHS only recommends it for up to 2 years at present.

On the other hand, the example that @nameey posted was not a good one as that person obviously made a lot of bad decisions around taking the drug, eg, she didn't need it for her weight and she didn't use a reputable pharmacy. I think a lot of positive things will come out of Ozempic where used correctly as there are potentially a lot of health benefits in losing weight. But I do worry that there will be some negative consequences too. If I were using it (and I did try it but it didn't agree with me), I would use a reputable pharmacist and only take it for up to the recommended 2 years.

Im pretty worried at the moment about the number of women i know who have spoken openly about being able to get it online, with BMIs between 25& 28, having provided no evidence of their actual weight. I know its proven to have real benefits (outweighing side effects) in those who are obese, and have no issue with it in that medical context, but its more than just the obese who are taking it. I'm hoping a bit tighter regulation will come in before nasty side effects do emerge

Not Ozempic but I've lost about 4st so far on Mounjaro and dropped my BMI from 43 to 34.

I'm very touched how concerned folks like the OP are about risks to my health from this medication. Thanks!

Jealous much

I've seen big improvements in my cholesterol, blood sugars and blood pressure since starting it

If you use a reputable online pharmacy it is very hard to lie to obtain it. I am on mj and buy from Lloyds chemist. I have to upload a video of me stepping on to the scales, full length photos etc and my gp is fully aware (and asked me how I was finding it when I had an econsult about something else), they get notified if I move up a dose.

I took it from June to early Dec and lost 3st3lbs alongside running/crossfit classes (which I had started last Jan). I took a few months off to see if the weight would come back on and it hasnt, I gained 4lbs since December.

The food noises have started to return so I have reordered and was dismayed to find I had to start at the lowest dose again. Yet this is reassuring from a clinical pov.

Basically, I have had no bad side effects, didnt gain loads (over Christmas I might add) when I stopped and have continued to exercise. BMI gone fron 41 to 33.

But yes, continue to rub your hands with glee that there will be some terrible side effect coming down the road for me...

Except it’s not a magic wand is it? It requires a significant diet change and ideally regular activity.

Totally disingenuous to suggest you’re in any way worried about the potential side effects of a medication you don’t take.
No other medication has had the media attention or scrutiny than this one - and the reason for that is that people think the fatties are cheating themselves slim - and how dare they! How many of the people worried about the potential side effects of WLI were concerned about the multitude of obesity related diseases those people on the drug were at risk from when they were obese? There’s nothing to feel superior about now because the obese are losing weight and people don’t like that!

This isn't true. I have a diabetic friend on Ozympic and she's on a dose of 10 (whatever that means, ml etc).

Exactly. Anyone who thinks any of the WLIs are a quick fix are ignorant. Yes, an aid but the weight doesn't magically dissolve.