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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

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to think more negative effects will come out from Ozempic use?

692 replies

nameey · 22/02/2025 11:12

Just read that the 30 year old singer Avery has been diagnosed with osteoporosis due to Ozempic use. Looks like this could be the start of many conditions coming out.

I know Ozempic is incredibly helpful for a lot of people but losing weight but then having osteoporosis does not seem worth it.

AIBU?

OP posts:
Twiglets1 · 22/02/2025 16:55

I think it’s hard to have an honest conversation on this subject as those taking it get very defensive. But it would be good to have an honest conversation about the potential risks as well as benefits for people taking it for longer than 2 years who aren’t obese.

Titasaducksarse · 22/02/2025 16:55

Twiglets1 · 22/02/2025 16:55

I think it’s hard to have an honest conversation on this subject as those taking it get very defensive. But it would be good to have an honest conversation about the potential risks as well as benefits for people taking it for longer than 2 years who aren’t obese.

I'll give you a 100% honest conversation. No problem at all.

Twiglets1 · 22/02/2025 16:58

Titasaducksarse · 22/02/2025 16:55

I'll give you a 100% honest conversation. No problem at all.

Good hopefully lots of us will have one on this thread without an assumption being made that anyone who mentions anything negative is completely anti weight loss drugs & judgemental against the people using them.

SwingTheMonkey · 22/02/2025 16:59

Twiglets1 · 22/02/2025 16:55

I think it’s hard to have an honest conversation on this subject as those taking it get very defensive. But it would be good to have an honest conversation about the potential risks as well as benefits for people taking it for longer than 2 years who aren’t obese.

Why? Why does it concern you? Are you keen to have conversations with other people about medications they’re on that doesn’t concern you in any way?

Dueanamechange2025 · 22/02/2025 17:00

Twiglets1 · 22/02/2025 16:55

I think it’s hard to have an honest conversation on this subject as those taking it get very defensive. But it would be good to have an honest conversation about the potential risks as well as benefits for people taking it for longer than 2 years who aren’t obese.

I’m very open to an honest conversation as long as no one starts with comments like id love a magic wand like earlier in the post.

I am concerned there maybe potential long term side effects that we don’t yet know however, I KNOW there are long term highly likely effects of me remaining obese.

Titasaducksarse · 22/02/2025 17:05

The sad thing is, unless you've struggled with your weight you'll never understand the mental torment that goes with it.
The constant exhaustion of choosing what to eat, mental mathematics of 'if I eat that I'll have to do x in gym', the denying self of food then the guilt when you 'fall off the wagon'. The shame, the self loathing. The feeling you're not 'allowed' to enjoy food publicly in case someone thinks 'look at that fatty having some chips '.
This is just the tip of the iceberg.

I'm not saying everyone who is overweight feels like me but this mental torture is what Mounjaro has removed. I can finally approach food in what I consider a normal way. I eat now for fuel. I don't binge. I make good choices. There's no drama.

Mounjaro has been a miracle to me.

This honest enough for you?

Twiglets1 · 22/02/2025 17:06

SwingTheMonkey · 22/02/2025 16:59

Why? Why does it concern you? Are you keen to have conversations with other people about medications they’re on that doesn’t concern you in any way?

It concerns me because as I mentioned earlier in the thread I have tried Ozempic before and may try it again at some point in the future.

It’s an interesting subject from many different angles such as what would it do to the massive weight loss industry if proven to something people could take forever on a maintenance dose. It could change society. But personally, I am interested in discussing the potential problems as well as the huge benefits.

Twiglets1 · 22/02/2025 17:10

Only one person made that comment about the magic wand @Dueanamechange2025 & it certainly wasn’t me. I think most people on this thread aren’t minimising how hard it is to lose weight. And having tried Ozempic myself, I know it’s not an easy fix.

nameey · 22/02/2025 17:10

https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/

One year after withdrawal of once‐weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two‐thirds of their prior weight loss, with similar changes in cardiometabolic variables.

OP posts:
soupyspoon · 22/02/2025 17:12

Orangesandlemons77 · 22/02/2025 12:33

Osteoporosis is linked with underweight and eating disorders, I guess the link is with these rather than the meds themselves.

Absolutely this, using Ozempic or any other weight loss injection/medication or method itself does not cause or give someone osteoporosis, its caused by not having enough collagen and calcium to protect the bones and you lose bone density.

More likely if someone has an absorption difficulty or they are malnourished.

SwingTheMonkey · 22/02/2025 17:13

Twiglets1 · 22/02/2025 17:06

It concerns me because as I mentioned earlier in the thread I have tried Ozempic before and may try it again at some point in the future.

It’s an interesting subject from many different angles such as what would it do to the massive weight loss industry if proven to something people could take forever on a maintenance dose. It could change society. But personally, I am interested in discussing the potential problems as well as the huge benefits.

You’d have to have type 2 diabetes to be prescribed ozempic if you’re in the UK. It’s not licensed for weight loss alone.

It would decimate the weight loss industry if people could be on WLI long term. Which is one of the reasons there is a constant stream of negative press about them.

Titasaducksarse · 22/02/2025 17:13

I'm conscious of bone density as a perimenopausal woman and started lifting weights at the gym again within couple of weeks of starting WLI

Cloney · 22/02/2025 17:14

You can't get osteoporosis within a few weeks from a medication. She's just lying about it - if she's anorexic then her body will have been fucked for years.

SilenceInside · 22/02/2025 17:15

nameey · 22/02/2025 17:10

https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/

One year after withdrawal of once‐weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two‐thirds of their prior weight loss, with similar changes in cardiometabolic variables.

What's your point here? That this is a better outcome than traditional dieting programmes?

BeardofHagrid · 22/02/2025 17:22

Someone told me ages ago that it will cause an epidemic of pancreatic cancer. Seriously messing around with your anatomy is never worth it imo.

Orangesandlemons77 · 22/02/2025 17:22

"admitted she took the weight-loss drug after struggling with an eating disorder."

MJMaude · 22/02/2025 17:24

BeardofHagrid · 22/02/2025 17:22

Someone told me ages ago that it will cause an epidemic of pancreatic cancer. Seriously messing around with your anatomy is never worth it imo.

After all there are no risks at all associated with obesity are there? Stay fat fatties - know your place!

OldChairMan · 22/02/2025 17:24

nameey · 22/02/2025 17:10

https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/

One year after withdrawal of once‐weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two‐thirds of their prior weight loss, with similar changes in cardiometabolic variables.

There areplenty of endocrinologists and other doctors who accept that it will be a long-term, potentially life-long medication for some. As blood pressure medication or statins are.

What is your experience of this drug class, OP?

maddening · 22/02/2025 17:25

It has been used for years by diabetics ' are we seeing huge issues with that population?

soupyspoon · 22/02/2025 17:25

I can only just about read it due to ad blocker but this is a right pile of shit

Shes only been on it a year, how much weight did she lose?

Weight loss in one year (even if its a huge 12 stone or something) isnt going to give someone osteoporosis, its something that develops over many years

nameey · 22/02/2025 17:26

It was here but been reported in many places:

https://www.aol.com/woman-shock-ozempic-usage-gave-213750627.html

OP posts:
Glorybox2025 · 22/02/2025 17:26

nameey · 22/02/2025 17:10

https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/

One year after withdrawal of once‐weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two‐thirds of their prior weight loss, with similar changes in cardiometabolic variables.

And?

OldChairMan · 22/02/2025 17:27

BeardofHagrid · 22/02/2025 17:22

Someone told me ages ago that it will cause an epidemic of pancreatic cancer. Seriously messing around with your anatomy is never worth it imo.

🤦🏻‍♀️ Messing with your anatomy? Do you perhaps mean physiology? By that measure all drugs would be avoided.

"Someone one told me ages ago..." is quite the source for medical information.

LionME · 22/02/2025 17:27

MigGril · 22/02/2025 13:55

The dose for diabetes is a lot lower though. Drugs can cause more issues at higher doses.

I don't have a problem for people using them if they are clinicly obese. I think it can be a very helpful tool, but the way people can currently accessing it is the issue. There needs to be more medical oversite.

I watched an interesting YouTube video from a Doctor in the US who has been using these drugs for a number of years already. She said you really need to do resistance training when using them in order to not end up with muscle and bone issue due to the rapid weight loss.

I think one very big issue is that people use it to loose weight as fast as possible. Like the 3stones in 3 months mentioned on this thread.

At that pace, regardless of how you loose weight, you’re going to loose muscle.
Much better to loose weight slowly (1~2 lb a week, as advised for other diets). But people are approaching that as they do dieting - quick and strong wins are always seen as the best. It’s very visible on the MJ threads on MN.

So basically, it’s not the medication that is an issue. It’s the way people approach weight loss as a whole.

And yes resistance training would help too. As would changing the way you eat (aka full lifestyle change) rather than just looking at scales.