As an American, the main reason for my British family members is the same reason I didn't apply for my British children to be US citizens - US overreach, largely in the financial sector.
If you've seen forms with 'Are you a US person for tax purposes' or more recently added asking where you were born, some where your parents were born, this is part of it and while it's called a citizenship based tax system, it has been extended to those on or who have had long term US visas (which is why they ask US person not US citizen), which can cause complications if you choose to return. While the US struggles to enforce the laws for those of us living abroad (compliance rate is 2-5%), some banks and other financial institutions are skittish of the threats the US has made around working with those connected to the US. You'd probably be able to avoid it as they often try to suss this out with asking for birthplace, but it is an issue and some banks will refuse financial products like ISAs and such where the UK's tax laws can cause issues with the US. I can't even get my will updated without having to discuss my US tax status.
There is also the issue that any sons between 18-25 would be expected to register for Selective Service. This does apply to noncitizens living in the US.
if you work in any field that requires DBS, upon return you'll likely need a Certificate of Good Character from the US embassy to continue that work. If you were to work in that in the US, you'll likely need similar from the UK. Background checks in general are more complicated.
There can also be issues around pensions in multiple countries, particularly when the US is involved. That's something I would get professional advice on as it can get complicated.
I also don't rate US healthcare, especially if kids are involved. Unlike in the UK where any of my kids can get medical care on their own if they had an emergency and I'm not available, that's really difficult to do in the US. As a teenager I presented at the ER on my own and because I wasn't in immediate threat of death, I was put in a side room to wait for a parent which took hours as he wasn't in-state at the time. The idea it's 'very good' erases difficulties of access and what I guess we could call a zip code and medical professional lottery - there is an incentive to 'wait and see' that some professionals exploit and some areas just don't have the resources. It's taken a lot to fix the health issues from the poor US healthcare I grew up with, and I still find issues now and then.
I was able to manage fine in the US as a nondriver, but you do have to be far more selective in where you live compared to the UK to get by without access to a car.
Really, the guns and such is really at the bottom of my list. My family regularly left the doors unlocked (never gave us kids a key), never had an issue. I didn't see a gun in person until I was an adult and visiting London. Being in a Northeast coastal area, it probably won't be as much of an issue, though there will likely be some gun owners with some of the wildlife. Not dealing with bears and such is another plus of having left the States.