I don't mind an ensuite, but I'd rather have a bathroom accessible to all bedrooms.
For example, a lot of people suggested an ensuite when we wanted an upstairs shower room (our only bathroom was downstairs).
My thoughts were that it would leave the occupants of the other two bedrooms needing to still traipse downstairs at 4am for a wee, or walk through our bedroom.
We stole a bit of the third bedroom (bedrooms add a lit of value here so we couldn't afford to lose one as it would devalue the house; small 3rd bedrooms are common locally so our 6'6" x 9' one is actually not a bad size).
In theory a future owner could easily move the doir if they wanted an ensuite though. It would only save you about 4 steps as the door to the shower room is next to ours 