Firstly U asked me to provide a reference that blood transfusion caused immune suppression ...which I did.. it’s obvipusly a phenomenon you’re not familiar with.
Which I thanked you for. It's not unreasonable to think of it, and I can think of a mechanism, but not to the extent of AIDS that can lead to people dying. I'm not an immunologist, or transfusion expert. I work with the germs themselves.
Second: AIDS is simply immune suppression allegedly caused by the HIV retro virus. There are NO new diseases associated with ‘AIDS’. They are all illnesses that existed long before HIV and were known to be caused by immune suppression due to other issues.
Yes, and yes. It has nothing to do with HIV causing AIDS, which is a specific condition.
The diseases associated with AIDS are called "opportunistic diseases", because they are more common in AIDS patients and some of them rarely cause illness in immunocompetent individuals, and because the extent of these diseases is much worse in AIDS patients. As it is in many other immunossupressed individuals. We tend not to talk about AIDS patients in relation to risk for these diseases, but immunodeficient/supressed or not immunocompetent individuals.
But, when an individual infected with HIV shows up with these diseases, then it's classified as not just infected, but as having the condition named AIDS.
The problem with these diseases when associated with AIDS (and other immunesupressions) is that treatment alone doesn't work well. The immunesupression must be addressed as well. HAART has also helped decrease the incidence and seriousness of these diseases.
I work with one of them. The incidence of this particular disease rose in Europe with the AIDS epidemic and declined significantly with HAART implementation. AIDS patients with this disease couldn't get rid of it unless their CD4 count was sufficiently high.
I doubt you could tell the difference between immune suppression alledgedly caused by HIV vs immune suppression caused by meth or repeated blood transfusions (other than the presence of antibodies to so called HIV... which aren’t exclusive to HIV) .....because ‘AIDS’ presents so differently in each individual
Ahhhh. Before HIV was associated with AIDS, AIDS was defined as a specific condition. It is defined by a low CD4+ cell count. CD4 lymphocytes, or T helper cells, are a class of white blood cells that produce cytokines. There are also CD8+ lymphocytes, which are the ones that produce antibodies, natural killer cells, and a couple of others. More may yet be discovered.
Other types of immunesupression are more generalist, or affect other types of cells, or affect macrophages.
The thing about HIV is that its presence does leave to destruction of CD4+ cells. The mechanism of entry and how it affects the cell is well studied.
A 2012 summary: www.ncbi.nlm.nih.gov/pmc/articles/PMC3405824/
There's also a lot known about how HIV kills CD4+ cells (infected and not infected)
A 2014 summary: www.ncbi.nlm.nih.gov/pmc/articles/PMC4452072/
(from quick google. HIV is not my field of study)
HIV is not only detected by the presence of antibodies against HIV. It is also detected by the presence of antigens (proteins of the virus itself) and by the presence of nucleic acids. Viral RNA can be detected specifically and shown to be HIV, and not any other retrovirus.
A quick look at sensitivity and specificity of a rapid diagnostic test (www.ncbi.nlm.nih.gov/pmc/articles/PMC4756447/) shows "100 % sensitivity and 100 % specificity with whole blood specimen and 100 % sensitivity and 82.86 % specificity with serum specimen for the detection of HIV-1"
That's within the parameters of most diagnostic tests and it is actually quite good compared to most. This is not considered poor specificity, particularly if you look at the results from whole blood.
Mind, you that this is a rapid first line test. Current tests done in labs are more sensitive and specific too. And for diagnosis confirmation, labs will do more than one test (as a pp posted earlier) because no lab wants to give a false positive or negative results.
So, it's not true at all that diagnosis of HIV is not accurate.
The problem with all your messy explanations about injectable drugs, anal sex, antibiotics and transfusions is that there is no mechanism to explain how all those different things can possibly cause specific CD4+ count defficiency.
Whereas with HIV it can be seen and tested in the lab.