Stewie,
Maggie Thatcher changed a lot of people's views of what women could do, regardless of her own politics (which were highly, arguably too, meritocratic). Seeing a woman as PM in 1979 was a real eye opener for a generation of people growing up, including me as a 14 year old. And, let's not forget, as opposed to 95% of MPS, she had a degree in a hard science from a top university.
Dismissing the problems of poorly educated men as their own fault or, even worse, labelling them as in need of professional help, does no one any favours. There were no less "SEN" men in years gone past but there were a lot more jobs for working class males which are now done by robots or computers.
Back to Cameron. Stupid remark which does indeed sound bad in the flesh, especially the repetitions. On the other hand, not typical of the man who was clearly riled, and something that will blow over in days if not less.