This thread is really interesting. I've never had this conversation before.
I'm almost 44. So far I have no greys but my parents went grey late so that's no suprise.
Skin is OK thanks to my sunscreen obsession. But still I do have to wear tinted moisturiser most days, I look absolutely knackered barefaced. (Laura Mercier Illuminating one, a lifeline)
Also on the Mirena, so I suspect I will go through peri menopause without noticing much. At least that's what people say! I intend to basically use it like HRT.
I'm also "lucky" enough to have utterly shit eyesight and wear contacts, so am hoping if my prescription changes it won't make much difference. DH though has had to get glasses this year and it bothers him a lot. He refused to carry them around with him, insisting they're just reading glasses, but yesterday he had to sign something in a garage and he couldn't read what he was signing and was a bit depressed he was now going to be one of those guys that has to take out glasses in front of people just to sign his name in the right place. 
Also haven't had any parents in several years. My 30s were hugely traumatic with their slow declines and deaths, but I am conscious that it means I am "freer" than some of my friends in their late 40s/50s who are taking care of both kids and parents.
However I had kids around the turn of my 40s so I am still in the nappy stage and I do envy my friends who are now enjoying "me time". That is far off for me and my fitness and waistline have suffered as a result.
Sex drive has also diminished hugely. Or rather, I am still interested in my head but am always so tired that I just can't be arsed. DH is the same. At least we communicate about it and we refuse to let it stop entirely.
I had my first "invisible" night last Saturday. Out in a bar full of hot young things in the company of other 40 something women and nobody even glanced in our direction. It was a suprise as I've always been considered good looking and I was accustomed to being chatted up at the bar. But I may as well have been wearing camouflage. However I didn't entirely hate it. It meant that I got up and started dancing to "Come On Eileen" like a loon and didnt give a shiny shit what the men in the room thought of me. It was a bit liberating tbh.