What is interesting is that the male that did this for 6 weeks exclusively was taking 50 mg twice a day of Spironolactone and in that documentation for this study I could find that this was lowered. However, the study authors did mention a study of women taking 25 mg and THAT the canrenone component that was considered risky only being 0.2% and considered ‘safe’. So this male still seemed to be taking double and the level of Spironolactone in the milk had NOT be assessed as safe. There seems to be a hand waving away of this fact in the study.
This is from this study linked below.
”At the time of our first visit, she was taking spironolactone 50 mg po bid, estradiol 2 mg po bid, and micronized progesterone 100 mg po bid. “
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779241
The study they quoted the 0.2% from says:
“The major metabolite of spironolactone, canrenone, was measured in the serum and milk of a 17-day postpartum woman who was taking 25 mg of spironolactone four times daily. Milk canrenone levels 2 hours after the dose were 104 mcg/L, and 47 mcg/L at 14.5 hours after the dose. The authors estimated that the nursing infant would receive about 0.2% of the mother's total daily dosage in the form of canrenone.1] Active sulfur-containing metabolites were not measured.”
https://www.ncbi.nlm.nih.gov/books/NBK501101/
I have now found this to be considered a ‘no’ effect on the infant written up.
https://www.drugs.com/breastfeeding/spironolactone.html#
It is notable (I might have missed it though) that I was unable to find the sex of the male fed infant. Because spironolactone has been noted for causing development issue for male sex organs on male foetuses in pregnancy.
This article is relevant to the first link.
https://www.newscientist.com/article/2161151-transgender-woman-is-first-to-be-able-to-breastfeed-her-baby/?utm_source=rakuten&utm_medium=affiliate&utm_campaign=2116208:Skimlinks.com&utm_content=10&ranMID=47192&ranEAID=TnL5HPStwNw&ranSiteID=TnL5HPStwNw-uOWyW0a0EHFcOxL5MmCf5Q&utm_source=rakuten&utm_medium=affiliate&utm_campaign=2116208:Skimlinks.com&utm_content=10&ranMID=47192&ranEAID=TnL5HPStwNw&ranSiteID=TnL5HPStwNw-eFdm05QNJngWSRNMPW32yA#ixzz6f2Pil0Ik
“However, the woman’s breastmilk has not been assessed yet, so we don’t know if it has the same mix of components as in milk from new gestational mothers. This means the practice cannot yet be recommended, says Madeline Deutsch at the University of California, San Francisco. She says she can see the potential benefits of breastfeeding, but that the long-term impact of this milk on the baby – including on subtle measures like IQ – is unknown.”
“Deutsch herself is a transgender woman with a six-month-old baby who is currently being breastfed by Deutsch’s wife, who was the gestational mother. “I am very sad not to be able to breastfeed her and at the same time I did not consider doing this for the above reasons,” she says.”
I believe Dr Deutsch is a director of clinical services at the Center of Excellence for Transgender Health at the University of California San Francisco.
But fuck. What would Dr Deutsch know, eh?