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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

May 2026 Mounjaro starters - thread 2

537 replies

madeinthe80z · 20/06/2026 04:47

Can’t believe we are in a new thread! Keep It up everyone StarSmileStar

OP posts:
Thread gallery
12
madeinthe80z · 06/08/2026 14:33

Boreded · 06/08/2026 13:33

No idea…I’ve been wearing the same clothes throughout as I wear pj bottoms and hoodies in the house, and jeans and one of three floaty tops when I go out. They are extremely loose now though.

I suspect I should have been wearing a 24 and now I’m on a 20

Trousers I’m wearing a 15 (love half sizes at next) as I’ve always been weirdly shaped so thin on the bottom despite being this weight

Next do half sizes?!!! I’ve never seen or heard of this! Need to investigate…

OP posts:
Boreded · 06/08/2026 15:00

madeinthe80z · 06/08/2026 14:33

Next do half sizes?!!! I’ve never seen or heard of this! Need to investigate…

Yeah in their jeans. It’s great for when you are in between.

MrsO2b · 06/08/2026 15:16

madeinthe80z · 06/08/2026 14:33

Next do half sizes?!!! I’ve never seen or heard of this! Need to investigate…

I've never seen them in there, or online....?

Boreded · 06/08/2026 17:14

MrsO2b · 06/08/2026 15:16

I've never seen them in there, or online....?

Not sure if they are in store. I get them online.

Boreded · 06/08/2026 17:17

https://www.next.co.uk/style/su767523/h57343

May 2026 Mounjaro starters - thread 2
PuppyKeep · 07/08/2026 11:47

2lbs lost this week after zero last week, so not stellar.

Also I'm still hungry. Jabbed yesterday.

What's happening?!

PuppyKeep · 07/08/2026 11:57

I wonder if the efficacy of the medication reduces after that 30 day window from first jab?

7238SM · 07/08/2026 12:03

@PuppyKeep Apologies I didn't link the pen tips in my earlier post. Every time I tried, it kept showing my personal log in info/address etc, hence I just sent the exact wording from the website. I someone else did manage to link them for you though, which are the same ones I bought.

Boreded · 07/08/2026 14:58

PuppyKeep · 07/08/2026 11:47

2lbs lost this week after zero last week, so not stellar.

Also I'm still hungry. Jabbed yesterday.

What's happening?!

But the medication is still sealed even if you squeeze some out, it’s not getting air back in or anything to react with. Not sure what would make it less effective being open for extra days vs sat in the fridge for 3 months unopened. So I would like to think it didn’t make a difference.

Is it possible that the jab just hasn’t got into your system fully yet? Maybe the hunger will die off a bit.

Good job on the 2lbs this week. What does that put you on so far?

TeamsThemeTune · 07/08/2026 18:37

PuppyKeep · 07/08/2026 11:57

I wonder if the efficacy of the medication reduces after that 30 day window from first jab?

I very much doubt it would lose efficacy that quickly - the 30 days is there purely because that's what it's tested for. There's no mileage in it for the manufacturer to tell you it's still OK at 60 or 90 days is there? Bodies are just weird sometimes. I lost 50 grams one week, and 1.25kg the next - there's no rhyme or reason to it.

I fully intend to go over 30 days with my next pen, and I don't even keep it in the fridge. (I'm not suggesting anyone should do the same, but personally I'm happy with the risk. And I'm actually a risk manager in real life!)

mollio · 07/08/2026 22:13

I am off on holidays tomorrow for a week and I have a dilemma . I have had such huge suppression this week I could barely eat …… and don’t know whether to :

  1. take my full 5mg
  2. Take 2.5
  3. skip a week

I’m not going to take the pen with me as it’s a palaver , it’s a full new pen and it’s going to be very hot there ….. I lost about 2-3 lbs this week quite suddenly after a regular 1 lb a week up to now . Maybe that’s why I feel shit ! Strangely I have felt better after exercising - less nauseous

madeinthe80z · 07/08/2026 22:19

mollio · 07/08/2026 22:13

I am off on holidays tomorrow for a week and I have a dilemma . I have had such huge suppression this week I could barely eat …… and don’t know whether to :

  1. take my full 5mg
  2. Take 2.5
  3. skip a week

I’m not going to take the pen with me as it’s a palaver , it’s a full new pen and it’s going to be very hot there ….. I lost about 2-3 lbs this week quite suddenly after a regular 1 lb a week up to now . Maybe that’s why I feel shit ! Strangely I have felt better after exercising - less nauseous

Edited

What week of 5mg are you on? I found after jab 3 my suppression was the highest ever. But jab 4 of 5mg this week has been a lot less exciting on that front! I’d be tempted to do 2.5mg I think but probably would have done it a bit earlier than the day before or day you’re going. If you do it as soon as you get back, you’ve essentially only missed one dose. What feels right for you?

OP posts:
mollio · 07/08/2026 22:31

Oh that’s interesting , it would be my 6th 5mg though . I used the full 5mg pen plus golden dose ( maybe I didn’t measure the GD properly ? Actually come to think of it , I was really sick after the last GD of 3.75 … probably coincidence ! I want to enjoy the holiday but don’t want tohlingbof a break when it’s working so well . Maybe 2.5 …… I was trying to space out and time it better but started too late two weeks ago , I should have manipulated days a month ago

madeinthe80z · 07/08/2026 23:10

mollio · 07/08/2026 22:31

Oh that’s interesting , it would be my 6th 5mg though . I used the full 5mg pen plus golden dose ( maybe I didn’t measure the GD properly ? Actually come to think of it , I was really sick after the last GD of 3.75 … probably coincidence ! I want to enjoy the holiday but don’t want tohlingbof a break when it’s working so well . Maybe 2.5 …… I was trying to space out and time it better but started too late two weeks ago , I should have manipulated days a month ago

How much did you take as your golden dose?

honestly I think the holiday dilemma is real (I started a thread on it!) and I really don’t know what to do either. I think in reality I just can’t be bothered with taking the pen with me!

OP posts:
mollio · 07/08/2026 23:15

I forced the pen and clicked to 1 so it SHOULD just be a regular dose. But n previous golden dose I used an insulin pen and withdrew it , but I decided to see if the pen would click on and it did quite easily ( with a bit of force )

madeinthe80z · 07/08/2026 23:35

mollio · 07/08/2026 23:15

I forced the pen and clicked to 1 so it SHOULD just be a regular dose. But n previous golden dose I used an insulin pen and withdrew it , but I decided to see if the pen would click on and it did quite easily ( with a bit of force )

Yep that should be fine then. I’ve only ever done the forced click method unfortunately the 5mg pens don’t have the golden dose 😭

OP posts:
Boreded · 08/08/2026 01:31

madeinthe80z · 07/08/2026 23:10

How much did you take as your golden dose?

honestly I think the holiday dilemma is real (I started a thread on it!) and I really don’t know what to do either. I think in reality I just can’t be bothered with taking the pen with me!

I’ve decided not to jab on mine, I’ll do it a few days before, ride out the nausea, then try to force as much liquid in me for when I get there. I do Disney and always struggle with the heat and dehydration, and don’t eat much there so would be a bad choice for me to jab there I think.

Has anyone given you good advice on the thread…I’ll have to go take a look

Boreded · 08/08/2026 01:32

Have a nice holiday @mollio

mollio · 08/08/2026 06:22

Well I was all set to jab this morning before we set off , but I was too nauseous still so feck it , I didn’t ! I want to be able to have a spritz and a salad without feeling like puking ! So that’s that decision made ! Will let you know what it’s like to have the break . Am going to Nice where it’s 32/33 this week so want to enjoy !! Have a lovely weekend everyone

Changingplace · 08/08/2026 08:17

Weighed yesterday and I’ve lost a stone overall, slower loss than some but steady and I’m happy that I hope I’ll be more likely to keep it off.

I’ve stayed on 2.5mg too, not upped it because I’m getting a lot of suppression and I’d rather stick with where I’m at, I can’t stomach bread and totally off cheese which is unheard of for me 🤣

NettleTea · 08/08/2026 11:13

yes Im still getting good suppression I think on the 2.5. I seems to be able to make some good decisions although yesterday I relaise I overdid it as I had a lunch I had forgotten to log!

Boreded · 08/08/2026 11:55

Changingplace · 08/08/2026 08:17

Weighed yesterday and I’ve lost a stone overall, slower loss than some but steady and I’m happy that I hope I’ll be more likely to keep it off.

I’ve stayed on 2.5mg too, not upped it because I’m getting a lot of suppression and I’d rather stick with where I’m at, I can’t stomach bread and totally off cheese which is unheard of for me 🤣

Great job. What’s your goal loss?

Boreded · 08/08/2026 11:56

mollio · 08/08/2026 06:22

Well I was all set to jab this morning before we set off , but I was too nauseous still so feck it , I didn’t ! I want to be able to have a spritz and a salad without feeling like puking ! So that’s that decision made ! Will let you know what it’s like to have the break . Am going to Nice where it’s 32/33 this week so want to enjoy !! Have a lovely weekend everyone

Have a lovely time and enjoy being able to eat.

Hillsmakeyoustrong · 08/08/2026 12:22

@mollio I am also in Nice! Home on Monday. Its been absolutely roasting here, humid, so we have only ventured out in the evenings.

I also didnt jab before my holiday and to be honest the intense heat, along with a smaller appetite after week's of 1300 cal has meant ive largely stayed on track. Excepting a coke here and a violet ice cream there 😋

mollio · 08/08/2026 18:16

Hillsmakeyoustrong · 08/08/2026 12:22

@mollio I am also in Nice! Home on Monday. Its been absolutely roasting here, humid, so we have only ventured out in the evenings.

I also didnt jab before my holiday and to be honest the intense heat, along with a smaller appetite after week's of 1300 cal has meant ive largely stayed on track. Excepting a coke here and a violet ice cream there 😋

Oh wow hope you’re enjoyed the week , I adore Nice , so fab !! Yea it’s HOT HOT HOT and v humid . I am a puddle . I am v v glad I didn’t jab in the end , because I was only able to eat 1/3 of a Caesar salad ( but I did mange a whole Hugo Spritz 😆). Just watched the women’s Tour de France go past - how they do it in this heat , haven’t a clue !!