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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Injection site choice

33 replies

madeinthe80z · 11/05/2026 13:02

Hi all

Do you have a preferred injection site and why??

I’ve seen a lot of people talking about their preferred injection site, e.g. more suppression in the tummy, more consistent supression in the thighs, more side effects in the arm etc etc.

Ive done each thigh so far (only in week 2) but I’m really curious on peoples views. I’m tempted to stick to the thighs because I’ve not had too many side effects and I’m scared based on what others have said about worse side effects in different sites! Help me decide!

OP posts:
Kitt1 · 11/05/2026 13:03

I don’t think it makes any difference where you inject. Just do it where you’re most comfortable.

I prefer tummy as that’s the easiest option for me.

Reginaphalangeeeee · 11/05/2026 13:08

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SilenceInside · 11/05/2026 13:10

I've always done stomach - largest and closest target! There's not a huge amount of evidence that it makes much of a difference. So do whatever suits for you.

Pamnn82 · 11/05/2026 13:13

I’ve inject into my thigh, I doubt it makes much difference.

IwanttoWFH · 11/05/2026 13:30

I injected into my stomach for a year. I then noticed I wasn’t getting as much suppression, so I swapped to my thigh. Apart from bruising like a b*tch, I think the suppression is much better!

madeinthe80z · 11/05/2026 15:11

Thanks all - good to hear other real life experiences. I saw an instagram video of a guy who rated each injection site out of 10, and even each arm was massively different, I was like…huh?!

I’m gonna stick with my thigh for another week and then potentially move to my stomach if I feel any reduced effectiveness vs other weeks as it would be great if that worked instead of having to move up to 5mg sooner!

OP posts:
VioletandMauve · 11/05/2026 15:20

When I started out 6 months ago my aim was to rotate sites, so left thigh, right thigh, left stomach, right stomach. Did the first two in my thighs, then on the 3rd jab which I tried into my stomach, the pen jammed! I panicked and jabbed it into my thigh and all was well.

Haven’t tried anywhere else apart from my thighs since and all’s good!

twilightcafe · 11/05/2026 15:20

Stomach area only. It's the part of my body with the most fat, so the injection doesn't hurt. I tried my thigh but it was too ouchy for me.

Woo383040 · 11/05/2026 15:35

Thigh only for me. They are my meatiest part and I find it easier.

reluctantbrit · 11/05/2026 17:25

I was wondering about this as well as I saw a similar thing on Threads.

I inject near the bellybutton, until recently my largest area for the last 9 months. But my suppression is going down and I wonder if it is worth a try,

Let‘s see if I remember it in a week.

dizzyupthegirl86 · 11/05/2026 18:37

I inject my arm as it always feels like it works better, I know there’s no scientific evidence but that’s just what I’ve found! I started having my stomach and then after a couple of months decided to try my arm and it felt so much stronger. Then I did my stomach again and felt nothing!

flip side of that is that I’ve gone up to 5mg last night and have jabbed my stomach as I’d rather it not be as strong until I get used to it.

Usernameismyname01 · 11/05/2026 18:52

Stomach here but that’s mainly because I’m going on holiday soon and I always have a reaction mark to the injection of about 3cm oval and it lasts about 3 wks until it clears. So my bikini bottoms need to cover it

dizzyupthegirl86 · 11/05/2026 20:04

Usernameismyname01 · 11/05/2026 18:52

Stomach here but that’s mainly because I’m going on holiday soon and I always have a reaction mark to the injection of about 3cm oval and it lasts about 3 wks until it clears. So my bikini bottoms need to cover it

you could try a longer needle - I occasionally had a reaction and when I moved to longer needles, I haven’t had one since!

VelociraptorsVelociRapping · 11/05/2026 20:18

I did thigh at first and then found I had dramatically higher suppression if I injected my stomach.

Safarisagoody · 12/05/2026 07:03

The manufacturers did a study into this, it does make a difference, it was part of the trials. The data is available on line, thighs had less side effects, and stomach was more potent, it was much more in depth, but a while since I read it and that was the highlights.

madeinthe80z · 12/05/2026 10:11

Safarisagoody · 12/05/2026 07:03

The manufacturers did a study into this, it does make a difference, it was part of the trials. The data is available on line, thighs had less side effects, and stomach was more potent, it was much more in depth, but a while since I read it and that was the highlights.

Yep I’d seen it too. It’s pretty medical-speaks but the long and short is it is deemed slightly more effective due to the body being better at absorbing peptides when administered to the abdomen, but it is really minor.

https://www.sciencedirect.com/science/article/abs/pii/S0168365921003369

OP posts:
Usernameismyname01 · 12/05/2026 13:13

dizzyupthegirl86 · 11/05/2026 20:04

you could try a longer needle - I occasionally had a reaction and when I moved to longer needles, I haven’t had one since!

Who do I get longer needles from? I just use what comes with it

dizzyupthegirl86 · 12/05/2026 13:21

Usernameismyname01 · 12/05/2026 13:13

Who do I get longer needles from? I just use what comes with it

I use shd medical. You can buy 6mm ones that fit onto the pen similar to the ones you get sent with the pen itself, but i just order normal needles with a syringe as I find it easier to jab my arm using them than the kwikpen. You want 29/30g (this is the thickness of the needle) and ones with a 1ml capacity (as one full dose is 0.6ml). 8mm/12mm is the length of the needle.

Comedycook · 12/05/2026 13:28

I tried my arm recently and suppression was really low

madeinthe80z · 12/05/2026 13:58

Comedycook · 12/05/2026 13:28

I tried my arm recently and suppression was really low

Interesting…
Ive just done my thigh again for jab 3. Nervous of side effects so when I have nowhere to be for 24 hours after a jab, I’m going to test my stomach! Will report back!

OP posts:
HeidiLite · 12/05/2026 15:12

I used to prefer stomach but had to switch to thigh as I now have no fat left on my stomach to jab. Guess the jabs have worked as intended :D

Reginaphalangeeeee · 12/05/2026 23:15

I do stomach. My thighs feel muscley since running, I recon it would hurt.

ButterYellowFlowers · 12/05/2026 23:17

All of that is nonsense. It’s just whichever you find easiest

ButterYellowFlowers · 12/05/2026 23:18

HeidiLite · 12/05/2026 15:12

I used to prefer stomach but had to switch to thigh as I now have no fat left on my stomach to jab. Guess the jabs have worked as intended :D

Nonsense. I was able to inject my biological medication into my stomach at a size 6. If you had 0 fat you’d be dead.