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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

OP posts:
Velvetandleather · 20/04/2026 11:47

Gotta love the fail and their obsession with weight loss injections, where they go on in the article to explain it’s all animal tested meds, but put wli to get clicks

sick fucks,

MoneyJo · 20/04/2026 12:03

I am interested to know if the OP has gone on to other medical boards to post links about animal testing of the drugs used by people on there. Cancer boards maybe?

Nah, thought not.

Mysticmaiden · 20/04/2026 12:06

All med trials use animals to test before the human trials stage unfortunately. Its the only way they can ensure safety and this has gone on for decades. I'd rather not have it this way but it's impossible to do it via other methods eg cell lines as these meds need the entire body system due to working in multiple ways.

Decacaffeinatednow · 20/04/2026 12:07

Why do people working in these labs have to resort to shock and horror tactics to get the testing conditions brought to public attention?

OP posts:
SilenceInside · 20/04/2026 12:11

They don’t. This DM article linking it to a specific medication has brought it to your attention and you have assumed that this is the first time that anyone has heard about it.

The MHRA in the UK are already committed to reducing and eventually removing the legal requirement for toxicity testing to be done on animals.

BauhausOfEliott · 20/04/2026 12:15

The vast majority of drugs are tested on animals during development. Pretty much any medication you’ve ever taken, including over the counter stuff, has definitely been tested on at least two different species of animal before it went to clinical trial on humans.

WeAllHaveWings · 20/04/2026 12:18

@Decacaffeinatednow

Is this news to you that human medications are tested on animals? Do you think other posters don't know human medications are testing on animals?

What do you want to achieve from this thread specifically for WLIs?

Motnight · 20/04/2026 12:19

WeAllHaveWings · 20/04/2026 12:18

@Decacaffeinatednow

Is this news to you that human medications are tested on animals? Do you think other posters don't know human medications are testing on animals?

What do you want to achieve from this thread specifically for WLIs?

Probably for a lot of posts saying fatties just need to eat less and move more and it's disgusting blah di blah

WeAllHaveWings · 20/04/2026 12:24

Motnight · 20/04/2026 12:19

Probably for a lot of posts saying fatties just need to eat less and move more and it's disgusting blah di blah

It does feel that way - we are fat, therefore we must also be thick and not know this.

But I am giving them the opportunity to show they are not so uneducated and to engage with facts in a more balanced, respectful, and informed way.

SilenceInside · 20/04/2026 12:27

Here is a recent statement from the MHRA from March this year,

https://www.gov.uk/government/news/mhra-action-boosts-drive-to-phase-out-animal-testing

What are your thoughts about this, @Decacaffeinatednow ?

There is also this longer term government strategy document from Nov 2025:

https://www.gov.uk/government/publications/replacing-animals-in-science-strategy/replacing-animals-in-science-a-strategy-to-support-the-development-validation-and-uptake-of-alternative-methods

reptilemad1985 · 20/04/2026 12:30

they should use all the pedos rapists and murderers instead

Velvetandleather · 20/04/2026 12:33

I can’t beleive you posted this on the weight loss injections board as well op. It’s all drugs. Surely no one didn’t know that.

ThisOneLife · 20/04/2026 12:36

SilenceInside · 20/04/2026 12:11

They don’t. This DM article linking it to a specific medication has brought it to your attention and you have assumed that this is the first time that anyone has heard about it.

The MHRA in the UK are already committed to reducing and eventually removing the legal requirement for toxicity testing to be done on animals.

Some level of animal testing of drugs before trialling on humans is inevitable. The controls are extremely strict.

Velvetandleather · 20/04/2026 12:36

Actually maybe you didn’t know that, even your title is indicating you didn’t.

advice, step away from the fail or apply critical thinking. Or maybe actually read the article.

ThisHazelPombear · 20/04/2026 12:51

90% trials fail when tested on humans. None of it should be going on.

People think I’m weird for not using products tested on animals like household cleaners/toiletries cosmetics etc but I can’t close my eyes to it. I’d use cruelty free meds if they existed.

Calliopespa · 20/04/2026 12:54

I hope that's an "after" shot because he certainly doesn't look like he needs them!

RedWineCupcakes · 20/04/2026 12:57

All drugs are tested on animals, they have to be or they cannot be licensed. The DM is sensationalising this about WLI to guilt trip the end users, approximately 80% of whom are women. It is just a continuation of the DM women hating.

Most people who work in the labs testing new pharmaceuticals are extremely caring and compassionate towards the animals that are used. They recognise that suffering can be a problem and do their utmost best to minimise it and treat animals with respect and dignity. But, as long as Regulatory Agencies insist on toxicity testing in order get products approved, the pharmaceutical industry has to comply.

Riapia · 20/04/2026 13:06

I’ve no doubt that all drugs to be used on animals are tested on humans first.
Aren’t they?
Would’nt seem fair otherwise, would it?

tinaabbot · 20/04/2026 13:06

ThisHazelPombear · 20/04/2026 12:51

90% trials fail when tested on humans. None of it should be going on.

People think I’m weird for not using products tested on animals like household cleaners/toiletries cosmetics etc but I can’t close my eyes to it. I’d use cruelty free meds if they existed.

90%?
That doesn’t sound correct, and is not representative of the part of the industry I work in. Plus most companies would be out of business by now if they were developing as far as human trials and then failing.

Where did you get the 90% stat from @ThisHazelPombear?

CautiousLurker2 · 20/04/2026 13:24

Just done a Google deepdive… paracetamol, hayfever meds, antibiotics, the contraceptive pill, decongestant… and so on, ALL TESTED on animals. Along with most diabetic meds, which GLP1s were and still are.

Unless OP wants to be performatively shocked about the state of animal testing in drug trials universally (and I’d respect that position, as I do people who have lobbied for safer and more humane treatment of animal subjects), then I have to infer that this is a goady anti-‘WLI’ post.

Allisnotlost1 · 20/04/2026 13:29

WeAllHaveWings · 20/04/2026 12:18

@Decacaffeinatednow

Is this news to you that human medications are tested on animals? Do you think other posters don't know human medications are testing on animals?

What do you want to achieve from this thread specifically for WLIs?

I don’t think it’s a terrible idea to draw attention to this, as part of a campaign to speed up the reduction/ending of animal testing for drugs. I’m not sure if that’s the OP’s motive but if so it’s a logical tactic.

It’s easy for people to dismiss many medications as not relevant, necessary for survival etc, and therefore no debate or urgency is ever generated. Something like WLIs is eye catching because of its current ubiquity, the fact that many many people are using it for lifestyle rather than life saving reasons, and the fact that new versions are being created to minimise side effects and maximise the market, necessitating even more testing.

Allisnotlost1 · 20/04/2026 13:30

CautiousLurker2 · 20/04/2026 13:24

Just done a Google deepdive… paracetamol, hayfever meds, antibiotics, the contraceptive pill, decongestant… and so on, ALL TESTED on animals. Along with most diabetic meds, which GLP1s were and still are.

Unless OP wants to be performatively shocked about the state of animal testing in drug trials universally (and I’d respect that position, as I do people who have lobbied for safer and more humane treatment of animal subjects), then I have to infer that this is a goady anti-‘WLI’ post.

But they’re not being tested NOW are they? They’ve been tested, yes, but not being redeveloped to be more palatable to a bigger market and therefore don’t need to be repeatedly tested on animals.

SilenceInside · 20/04/2026 13:33

@Allisnotlost1 they're not being repeatedly tested on animals though, as a result of being repurposed and developed. They have already passed the required toxicity testing, it surely isn't done again each time there are further clinical trials for other outcomes?

Allisnotlost1 · 20/04/2026 13:35

SilenceInside · 20/04/2026 13:33

@Allisnotlost1 they're not being repeatedly tested on animals though, as a result of being repurposed and developed. They have already passed the required toxicity testing, it surely isn't done again each time there are further clinical trials for other outcomes?

I believe that new versions are being tested yes, and that there are trials testing toxicity at different doses/side effects and interactions. happy to be corrected though.

CautiousLurker2 · 20/04/2026 13:36

Allisnotlost1 · 20/04/2026 13:29

I don’t think it’s a terrible idea to draw attention to this, as part of a campaign to speed up the reduction/ending of animal testing for drugs. I’m not sure if that’s the OP’s motive but if so it’s a logical tactic.

It’s easy for people to dismiss many medications as not relevant, necessary for survival etc, and therefore no debate or urgency is ever generated. Something like WLIs is eye catching because of its current ubiquity, the fact that many many people are using it for lifestyle rather than life saving reasons, and the fact that new versions are being created to minimise side effects and maximise the market, necessitating even more testing.

But WLI - or diabetic medications in the form of GLP1s - ARE lifesaving. People with diabetes die without them. Many obese individuals will die if their obesity is not managed.

This OP was not about the morality of animal testing generally as this would have been addressed in the OP - it was specifically about the use of animals in the development of GLP1 meds. And was the posting of an article they haven’t even read because it is behind a paywall.