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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

January 2026 Starters - dog-gone weightloss

996 replies

BooptotheFloof · 18/01/2026 12:24

I hope it’s okay to start a new thread as we are getting dangerously close to the end of thread 1

My current stats are

MJ 2.5mg just taken dose three
planning on staying on 2.5mg for my next pen
SW: 13 stone 9.4lbs
Week 1: lost 11 lbs
Week 2: lost 3 lbs
Total weightloss: 1 stone (a small jack russel terrier)
GW: 9 stone 7

We have some newbies joining mid month so let’s cheer them on - we’ve got this ladies!

OP posts:
Thread gallery
24
bookwormcrazy · 29/01/2026 18:07

AddUpToNothing · 29/01/2026 16:57

Depending on your priming method - you may find your golden dose is around 3.33mg (if you draw all the remaining liquid out rather than stopping at 0.6) so a nice stepping stone to 5mg.

I’m planning on injecting whatever amount is remaining in my pen on Saturday for my 5th dose. As I’m also a little worried about the jump from 2.5 to 5 and side effects with it being double what I’m used to.

That’s a great shout. I will see how much I get out of the pen.

Howmuchhowlong · 29/01/2026 18:11

For those of you who are using the golden dose, what do you do about reordering? Have a week break then order as usual? Or stockpile?

notcomfortable · 29/01/2026 18:15

Howmuchhowlong · 29/01/2026 18:11

For those of you who are using the golden dose, what do you do about reordering? Have a week break then order as usual? Or stockpile?

I always order around the two week mark so no gap

InstantRegret · 29/01/2026 19:08

@CatNoBag @AddUpToNothing @Perianth Thank you all for your kind words 🙏 I’ve now sat down for the evening with a cuppa and am feeling a lot calmer 😌 I’ve stocked up on medicine for every side effect I can think of so feeling prepared 👍🏻

@GhostHQ no advice but I can totally relate with the panicking and anxiety. I’m just going to take it day by day and remind myself that if it doesn’t agree with me then I can stop at any time. Maybe see how you feel by your next jab day and go from there?

Whoopdedoop · 29/01/2026 19:47

Hi - hope it’s okay to join! Just been approved for Wegovy 0.25, waiting for delivery. Hoping to go from 12st to 10.5st by end May - is this doable?

Apologies for a silly question - if Mounjaro starts at 2.5, does that mean MJ is ten times more effective?

TIA x

FrothyCothy · 29/01/2026 20:04

Whoopdedoop · 29/01/2026 19:47

Hi - hope it’s okay to join! Just been approved for Wegovy 0.25, waiting for delivery. Hoping to go from 12st to 10.5st by end May - is this doable?

Apologies for a silly question - if Mounjaro starts at 2.5, does that mean MJ is ten times more effective?

TIA x

It’s a different drug so measured by a different dosage.

Whoopdedoop · 29/01/2026 20:28

FrothyCothy · 29/01/2026 20:04

It’s a different drug so measured by a different dosage.

Oh - that makes sense! Thank you.

InstantRegret · 29/01/2026 22:04

@Peachypips78 How are you feeling now?
I’ve finally caught up with this thread and saw that you jabbed for the first time yesterday so only a day before me. Hoping it’s going ok for you?
I’m sat here waiting for the side effects to kick in having only jabbed 8 hours ago 😆

InstantRegret · 29/01/2026 22:13

Merluzzo · 25/01/2026 13:29

Just jumping on your thread with some info about the fifth dose of MJ. I started in May last year and have always used the “golden” dose, it’s too expensive to waste.

Don’t buy syringes from Amazon, they won’t be guaranteed sterile, you need a medical supplier like UK Medi for insulin syringes. A 1ml syringe will be ok, a full dose from your pen is 0.6ml. I often get 0.8 ml out of the pen, giving you a dose of 3.33mg from a 2.5mg pen, a nice stepping stone if you’re moving up to a higher dose pen.

Many people use this syringe, You insert the needle into the pen through the red seal and slowly extract all the remaining liquid, then inject as normal.

https://ukmedi.co.uk/products/fms-micro-syringe-32g-8mm-1ml-fms-fms-32g-10ml-ukmedi-co-uk

Some people (me included) are a bit scared of the needles on this syringe, it’s 8mm long compared to the 4mm pen needles you usually use. I use the Luer lock syringes and buy separate Luer lock 4mm needles. As the needles are detachable, I use 1 needle to extract the extra dose, then swap to a brand new needle to inject. The first time I did this the needle bent a little bit when I pushed it through the seal and I figured it might not be as sharp, I really didn’t want to inject myself with a blunt needle!

https://ukmedi.co.uk/products/1ml-unifix-luer-lock-syringe-unifix-ux1l-ukmedi-co-uk

https://ukmedi.co.uk/products/32g-pink-4mm-meso-relle-mesotherapy-needle-meso-relle-am324-ukmedi-co-uk

@Merluzzo This is really helpful 🙌🏻 Thank you so much for taking the time to share this.
I’ll probably be too scared to attempt it but it’s good to know how to do it if needed. Thank you 🙏

Rubytoes · 29/01/2026 22:21

I had my 4th jab of MJ a few days ago, but weight loss has really stalled and I regret not moving up to 5mg for my next pen. I'm feeling appetite suppression and am definitely eating less but I'm frustrated that it isn't showing on the scales, although the first week was good. I'm probably being impatient and should just avoid weighing so often.

I'm planning on using the golden dose next week but I need to read up on it a bit more. I already ordered received my next pen as I had the first pen a few weeks before I did the first jab. I prefer to have it to hand in case there are issues with delivery.

2026istheyear · 29/01/2026 23:25

Thank you to the poster who recommended the book Weightless. Really interesting read and great tips.

YouBelongWithMe · 30/01/2026 06:46

Been catching up with everyone - welcome to all the newbies!

Took dose 3 of WG last night. Week 2 really stalled for me. I've lost 1lb all week. I'm due my period in a couple of days so it might be that, but feeling a bit despondent.

Weight loss this week: 1lb
Weight loss overall: 8lb

notcomfortable · 30/01/2026 07:23

YouBelongWithMe · 30/01/2026 06:46

Been catching up with everyone - welcome to all the newbies!

Took dose 3 of WG last night. Week 2 really stalled for me. I've lost 1lb all week. I'm due my period in a couple of days so it might be that, but feeling a bit despondent.

Weight loss this week: 1lb
Weight loss overall: 8lb

I have only lost 6lb since I started
And I'm already on the next dose of mj
It isn't making any difference

Newstartplease24 · 30/01/2026 07:54

Morning all. I’m not sure I lost any weight this week (weigh in on Sunday) as I don’t feel particularly slimmer. But my digestion is so much better. I had awful cramps and bloating before and I guess it was poor diet - and calming it all down a bit has really helped how I feel physically and mentally. Embarrassing that I couldn’t do it on my own. But here we are.

I’m taking my week 2 dose of wegovy today. Earlier in the week I was eating a lot less but these past few days I’ve been quite tempted by random carby snacking again. I’ve held off more than I might have as I’ve been reminded it makes me feel awful.

sympathy to those who dont few they’re getting results. Some people really do just hang onto weight - ask me how I know 😆. For people like us I think the trick is consistency, not over thinking, finding something you can stick with and bloody well sticking with it. Punishment won’t work for us as it’s got to be long term and there’s only so much punishment you can live with before you say fuck it.

Onbdy · 30/01/2026 07:57

Weigh in 4 and I’ve lost a stone now 🎉
I’ve just done my first jab of my second 2.5 pen. I had really bad side effects during week 3 so decided to stick with 2.5 for another month. Almost regretting that now as I was fine last week. I’m still eating what I would normally eat following the WW diet but I only lost 1.5 pounds without MJ for the 6 weeks leading up to Christmas so MJ is definitely making a difference. Has anyone doubled up on a 2.5 dose towards the end of a pen?

blackandwhitefluffycat · 30/01/2026 08:11

5th jab day and a 6lb loss this week!

My stats:
5’6”
SW: 14.5
Week 1: lost 10lbs
Week 2: 0lbs
Week 3: 5lbs
Week 4 6lbs
Total weight loss: 1 stone 7 1b (21lbs)
CW: 12.12st
GW: 10 st

As said before, I’m doing exactly what I did last year for a month, when I didn’t lose a thing! I’m in peri and on a type of HRT which says weight gain is a common side effect, and after struggling with my weight since going on it MJ is really helping me to fight against it!

blackandwhitefluffycat · 30/01/2026 08:11

Onbdy · 30/01/2026 07:57

Weigh in 4 and I’ve lost a stone now 🎉
I’ve just done my first jab of my second 2.5 pen. I had really bad side effects during week 3 so decided to stick with 2.5 for another month. Almost regretting that now as I was fine last week. I’m still eating what I would normally eat following the WW diet but I only lost 1.5 pounds without MJ for the 6 weeks leading up to Christmas so MJ is definitely making a difference. Has anyone doubled up on a 2.5 dose towards the end of a pen?

Well done!

recruitretain · 30/01/2026 08:12

10 days in and it’s already changed my life this jab

January 2026 Starters - dog-gone weightloss
Etherealcelestialbeing · 30/01/2026 08:17

Not as much of a loss for my 2nd week - only 2lb.
However, I am due on my period soon and did have a lunch out with friends last weekend so I’m happy that the arrow is pointing downwards!

I got an email from my provider asking me to order my next pen. I was flip-flopping between 2.5 and 5mg. Then realised the order-by date was the same day so I kind of panicked and chose 5mg Smile I’m sure I didn’t need to order so early but at least it made my mind up quickly!
I am planning to try and get the full golden dose (which should be about 3mg?!) before going up to 5mg pen.

Question - if I buy 1ml needles, can I use them for the golden dose on the 5mg pen? Will it always be 0.6ml for a dose, even on higher strengths?

2026istheyear · 30/01/2026 09:03

Weigh in 4 and 3.3 pounds off this week 🎉 I have a 5mg pen but am only going to take 2.5 as it’s working really well. I can eat meals but just no urge to snack so don’t want any more suppression at the moment. Still doing lots of exercise. Downloaded nutracheck this morning so I can keep a better track of protein intake.

Had my first ‘you’ve lost weight’ yesterday (not from someone who knows I’m on MJ) which was very satisfying!

SW: 16 st 9 - 5ft 7
Wk 1: -8.6 lbs
Wk 2: -4.9 lbs
Wk 3: -2.7 lbs
Wk 4: -3.3 lbs
CW: 15 st 3.4
GW: 12 stone

January 2026 Starters - dog-gone weightloss
YellowStockings · 30/01/2026 09:10

Ok, a bit TMI but - I currently weigh every day unofficially (only record once a week though), and I weighed this morning before going to the loo (106.2kg) and after going twice (105.85)!!

Obviously I’ll assume the lower weight is the right one 😉 but it shows how huge fluctuations can be throughout the day. Now I’ve had breakfast and a cuppa it’s probably shot up again!

YellowStockings · 30/01/2026 09:28

Also I’ve just ordered the super expensive Zooki collagen gels to try next month, does anyone else use them? Hope they give my skin a nice boost as I’m worried about my skin / hair / nails!

2026istheyear · 30/01/2026 09:45

@YellowStockings I have been taking wild nutrition collagen and Ancient and Brave cocao and collagen for the same reasons! Will investigate the Zooki

Whatstfpoint · 30/01/2026 09:46

YellowStockings · 30/01/2026 09:10

Ok, a bit TMI but - I currently weigh every day unofficially (only record once a week though), and I weighed this morning before going to the loo (106.2kg) and after going twice (105.85)!!

Obviously I’ll assume the lower weight is the right one 😉 but it shows how huge fluctuations can be throughout the day. Now I’ve had breakfast and a cuppa it’s probably shot up again!

Yes the lower weight is the correct one 👌

goldylock · 30/01/2026 10:08

Day 2, Week 1, 5mg

I injected yest mid-morning, and don't feel any different-no effects.

Now, maybe am taking the appetite suppression effect too literal, which I only had the first week of 2.5 mg. I get hungry the same, but I don't crave anything, and it will be 5 weeks since I've had a bag of crisps, which is a huge thing for me, as a big crisp fiend. I don't think about them 🙈. I can't imaginary taste them.

So, maybe how it works for me is I still have a normal appetite but no cravings.