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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

September 25 starters - new year, new trousers.

520 replies

outofofficeagain · 21/12/2025 09:59

We won’t make it to Christmas without a new board.

Well done to everyone for getting this far and thank you for your company.

Here’s to a healthy and happy 2026.

OP posts:
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OneDayIWillLearn · 03/01/2026 10:57

Kazzaa46 · 01/01/2026 12:05

@Atalosswhat2do congratulations that’s amazing 🤩

I’ve been starving the last two days. Sweet cravings have been creeping back. I don’t know if it’s from overindulgence over Christmas or 5mg is no longer working. I had a massive carb craving yesterday morning but I am due on in a week so this could also be the reason but even before this, I’ve found I’m wanting bad foods again.

I’ve jabbed today which is one day early as I did try this once before and it brought back my suppression so fingers crossed. This was the end of my current pen but I have another 5mg in the fridge so I’m going to have to keep to this dose for now.

Happy new year 🥳

@Kazzaa46 Similar to you (though I’m on 3.75 or 4.00mg) - last week I’ve had some suppression in that I’m feeling full sooner and not constantly thinking about food. BUT I’ve been much more drawn to eating crap again - chocolate, crisps….and this morning I even had a left over Pop Tart because my husband offered it to me.

Not sure how much of this is due to being out of my food routine and eating crap which causes cravings…..or the dose being less effective. I think I’ll jab tomorrow - which is after 6 days rather than 7 - and I think I’ll go for the full 5mg. Though I might give it one last week on 4mg in case better habits/ routine solve the issue. I don’t know!

OneDayIWillLearn · 03/01/2026 11:09

I’ve been feeling a bit down about all the negative comments in the press/ social media (and on Mumset threads actually) about WLI, to coincide with New Year I suppose.

I have been recently open with a couple groups of friends that I’m using them, because the topic came up in general conversation and I wanted to add a more informed perspective and didn’t really feel the need to keep it hidden when the moment arose (they didn’t ask me and I don’t think my weight loss is quite enough to be very noticeable yet). Both times I found talking openly about it positive and quite a relief, and I genuinely don’t feel any shame or hesitancy about the decision to go on Mounjaro now for myself, though I did to begin with if I’m honest.

But seeing all the ignorant and judgemental comments floating around these last few days makes me realise what a deep well of negativity is out there and I can’t help finding it a bit of a downer.

Any else finding that? I was planning to try and massively reduce my social media use in January and this is making me think I need to get on with it!

outofofficeagain · 03/01/2026 11:24

I agree @OneDayIWillLearnit’s very complicated. There are lots of people I haven’t told and I try not to read too many comments.

On the other hand, I do find it fascinating.

Who benefits from WLI - Eli Lilly etc

Who loses

  • any organisation making money on people’s insecurity (Daily Mail)
  • UPF manufacturers (Unilever, Proctor & Gamble)
  • people who’s own self-esteem is weighed against other people, or who feel their worth is attached to their supposed ‘effort’ or moral superiority

From a media perspective, there is massive self-interest at play in discouraging their use.

I’m choosing to see it as a defiant act!

OP posts:
SerafinasGoose · 03/01/2026 11:26

No losses to report this week. Still spot on 13 st, but on the positive side I haven't gained anything. I deserved to because I went overboard on NYE: my friend hosted and cooked a range of amazing pies and lots of potatoes - always my greatest weakness. And we all had way too much alcohol!

Now pressing restart, and reminding myself how far I'd come before I got here.

Kazzaa46 · 03/01/2026 17:40

@OneDayIWillLearn When I stepped up to 5mg after a month of doing 3.75 and 4mg, I was amazed at the difference in suppression from that small increase, particularly the first month. I think you’re being really wise though staying as low as you can for as long as possible. I’m currently like this with 5mg, I’ll try anything not to have to increase.
I know what you mean about the negative press, everytime I open facebook there’s some negative news story on my feed. I’ve been open with everyone about taking MJ. Most people have been positive and the sceptics are now actually thinking about it themselves particularly after seeing my success and me sharing the other benefits I’ve experienced.
The way I see it is it is approved by WHO and the NHS. I watched an interesting video from a doctor on TikTok who was saying that there are many other newer drugs for other conditions that are not getting this attention but WLIs are constantly discussed due to biases and views in our society that obese people are somehow undeserving of medical help.
Weight management aside, I’d take MJ just for the benefits I’ve experienced with my peri symptoms, mental health and improvement in a skin condition I have.

familyornot · 03/01/2026 23:42

I was fully prepared to tell anyone who asked that I was on MJ, but when the opportunity presented itself I didn’t. It’s not because I’m ashamed and worried about judgement really, I’ve been doing this for 3 months now and at no point have I felt under pressure to lose weight like I have on previous diets. I’ve also told everyone previously and it made my weight a public conversation, at first it was ok but then after a while (and particularly when I was struggling) it started to upset me and I felt like I had no privacy. It was my own fault for telling everyone and being so vocal about my efforts. Ultimately, I started to put weight on and no one has mentioned weight to me again until last week when I met up with some ex work colleagues. They were telling me how fantastic I looked, which was lovely, but they assumed I was just ‘back on the diet’ and so I didn’t correct them. I guess I am in a way, I just don’t care about food anymore and so avoiding the wrong foods is much easier than it was before.

Still having a dilemma, I took 5mg out of the 7.5mg pen last week but I’ve eaten crap and most likely put weight on. I didn’t want to be feeling sick which is why I stuck to 5, but I think I’m not suppressed enough. It’s jab day tomorrow and I’m still trying to decide whether to stick with 5 again and focus on eating healthier than I have over Xmas or whether to move to 7.5 and risk feeling sick and barely being able to eat. It’s a difficult one! But my loss has pretty much stopped so I feel like I should move up.

I do need to focus on eating healthily, I’ve been relying on suppression alone for the last 2 weeks which I know is the wrong way to go about losing. My weight hasn’t moved since Boxing Day.

Chopsy123 · 04/01/2026 09:57

@familyornot We all need to change something about our eating habits long term otherwise, we wouldn’t all be on here, so you’re not alone in this dilemma. I also haven’t moved on the scales for the last couple of weeks. We’re in this together. 🤗

Christmas is the one time of year that we get a pass to eat crap with our friends and family, but it’s now January 2026 and time to start making serious decisions and changes for the good of our long term health.

Only you know how you feel on 5mg but if you think you mainly went off piste because of Christmas, then maybe it’s worth giving the 5mg another week?

I never eat breakfast which I know isn’t a good thing so I actually bought some weetabix yesterday. Haven’t eaten it since I was a kid. 😂

Both DH and DS (16) are fussy eaters and eat a pretty restrictive diet in their own way, which I realise has contributed to my issues so I need to forge my own path meals wise. I think I’m going to try and get DS to start cooking some of his own dinners from now on. (They’re mostly air fryer based!). Or join me in eating a wider variety of healthier foods. DH already sorts himself out.

SoUncertain · 04/01/2026 10:08

Don't be too hard on yourself, @familyornot ! Most people will have gained some weight over Christmas, so staying the same is still a big win!

I would maybe try another week at 5mg because eating junk does encourage your body to want more. You can always go up next week if you still feel suppression isn't where you want it

(Edit, sorry originally tagged wrong person)

tonybennscat · 04/01/2026 10:43

Happy new year to all.

I gained 2.5 lbs over Christmas which is a bit disappointing but I’ve lost 1.5 of those now. Currently 1st, 7lbs down on September which is slow compared to some I know but is still great.
I know I need to drink more water so that is my aim for the next week.

OneDayIWillLearn · 04/01/2026 14:31

@tonybennscat your loss is similar to mine. I’ve been trying to see it as a good thing though, slow and steady etc!

@familyornot I decided to stick on 4mg for one more week and decide about moving up to 5mg next week. My diet has been pretty crap for two weeks and I want to get back into my routine first. Plus we got a new puppy on Friday so I decided that was enough change for one week 😂

In other news, I took a radical approach to my clothes this morning and packed about 2/3rds of them away in suitcases which are under the spare bed. My clothes have got a bit out of control compared to the space available so I had a huge pile of clothes on top of my chest of drawers and I haven’t been able to decide what to do about them, especially as I’m still losing weight. Big chuck? Sell on Vinted? Buy a bigger wardrobe etc?? I read a blog post this morning by a woman who had packed all her children’s clothes away for the summer save a week’s worth of outfits and I thought ah-ha, I’d do that! I’ve kept more than a week’s worth but I basically took everything out of the drawers/ wardrobe and then put back just my few favourites of whatever I will realistically wear in the next few months. Everything else packed away. So 3-4 jumpers, 3 pairs of jeans, a couple of dresses, 7 t-shirts, 3 shirts. One skirt.

I’m going to get it all out at the end of March and decide what to keep (if anything) then and maybe I’ll do a Vinted session then, I don’t have the energy or mental space for selling on Vinted right now. I figure/ hope I’ll have lost a chunk more weight by then too.

Interested to hear if anyone else has found a good way of managing their clothes through this transitional period!

bluepaperwaspofbxl · 04/01/2026 15:46

@OneDayIWillLearn I'm in a weird inbetween stage with clothes. I have lots of clothes that will fit me once I've lost some more weight, but all of my clothes bought pre-current loss are too big, so I'm getting by on very little of the current stuff that I can get away with, like dresses and jeans that were way more snug before. Enjoy your new puppy! Hope the difficult stage doesn't last for too long!

Pinkbox · 04/01/2026 16:15

@OneDayIWillLearn I have been wondering what to do as well, I have some nearly new jeans which are falling down and loads of tops which seem baggy now. I want to put them on Vinted but then I panic that I’ll be one of those who put the weight back on and will need them all in the future. Obviously at that point I could buy new but it’s throwing money away.

outofofficeagain · 04/01/2026 18:12

I’ve been using Vinted as a swap shop. Sold things that are too big and bought new things in a lower size.

i’m going to do that until I’m down another dress size and then treat myself to new summee clothes.

i’ve got rid of all my size 18s so I absolutely cannot put the weight back on!

OP posts:
SoUncertain · 05/01/2026 14:27

OneDayIWillLearn · 04/01/2026 14:31

@tonybennscat your loss is similar to mine. I’ve been trying to see it as a good thing though, slow and steady etc!

@familyornot I decided to stick on 4mg for one more week and decide about moving up to 5mg next week. My diet has been pretty crap for two weeks and I want to get back into my routine first. Plus we got a new puppy on Friday so I decided that was enough change for one week 😂

In other news, I took a radical approach to my clothes this morning and packed about 2/3rds of them away in suitcases which are under the spare bed. My clothes have got a bit out of control compared to the space available so I had a huge pile of clothes on top of my chest of drawers and I haven’t been able to decide what to do about them, especially as I’m still losing weight. Big chuck? Sell on Vinted? Buy a bigger wardrobe etc?? I read a blog post this morning by a woman who had packed all her children’s clothes away for the summer save a week’s worth of outfits and I thought ah-ha, I’d do that! I’ve kept more than a week’s worth but I basically took everything out of the drawers/ wardrobe and then put back just my few favourites of whatever I will realistically wear in the next few months. Everything else packed away. So 3-4 jumpers, 3 pairs of jeans, a couple of dresses, 7 t-shirts, 3 shirts. One skirt.

I’m going to get it all out at the end of March and decide what to keep (if anything) then and maybe I’ll do a Vinted session then, I don’t have the energy or mental space for selling on Vinted right now. I figure/ hope I’ll have lost a chunk more weight by then too.

Interested to hear if anyone else has found a good way of managing their clothes through this transitional period!

My clothes are getting baggy and I've decided it's winter chic 😅

OneDayIWillLearn · 06/01/2026 11:16

Chuffed to weigh-in at 12 stone 1.25lbs this morning, 1.25lbs down on Christmas Eve exactly half way from my start weight to my provisional goal of 10 stone 7lbs (which would be BMI 23 - never weighed that little as an adult though so let’s see!)

Also NSV of having a new pair of barrel leg jeans off Vinted - size 14 but the advert said more like a 12….and they did up! On the snug side but wearable, and not even made of stretchy denim. My size 12 carrot jeans arrived from M and S and they can go on but not do up yet, so my aim is to be in them by Easter 💪. All quite motivating!

also @outofofficeagain i forgot to reply to your post but I keep thinking about it and yes, I like to think of taking MJ as an act of defiance too! I heard a talk in November about food security/ food trends and they were saying how worried all the UPF and junk food manufacturers are about WLI because of what it’ll do to their market and I was like ‘bloody about time too!!!’ No sympathy there I’m afraid.

Kazzaa46 · 06/01/2026 18:18

@OneDayIWillLearn well done 👏

I weighed this morning and I’ve maintained which I’m happy with as my diet hasn’t been great. I’ve stalled for 3 weeks now.

5mg has worn off today. Taking it a day early last week helped but I’m just not getting the effects from this dose any more that I used to. I know I need to move up but I’m getting close to target and have another 5mg pen to go. I’ve never done the GD before but have my current pen in the fridge with just the GD left. I may use this tomorrow and see if it gives me enough to do 6mg.

The insulin needle I have is 8mm but I know the pen needles are 4mm. What do others do please? Just insert it about half way?

SnowWhiteisMyFavourite · 07/01/2026 07:40

@Kazzaa46 I’ve used syringes with bigger needle for the golden dose and I have always inserted the needle fully into my skin. I do have a very big belly roll so I haven’t even thought about this being an issue 😄

SnowWhiteisMyFavourite · 07/01/2026 09:00

Happy New Year to you all! I went back to work on Monday after two weeks off and it feels so good to be back in a routine. Food during the holidays was really carb-heavy, so I was worried about cravings. I allowed myself to eat and drink what I wanted/what was offered, and I had several days where my calories were over 2,500. I tracked calories just to see how much I went over, and I tried not to feel guilty or restrict myself too much because I was “dieting”. (I’m trying to avoid thinking that I’m on diet, I want this to be a lifestyle change where holidays/random treats etc can be balanced over a long term period). I did continue to do my walks and my average weekly steps were over 10,000 with my average weekly calorie burn remaining over 450cals.

And it worked! I didn’t weigh myself after Christmas, but I have reached my first goal of 15st at some point between 20th December and 3rd January! Loss between this period was 2lbs. This is starting to feel like completely new territory, as I can’t really remember the last time I weighed this.

My next goal is 13st but I think I’ll need to break this down into smaller steps. In kg, I now weigh 95kg so I think the next big win is getting below 90kg.

Stats:
SW 19st 3lbs (30/08/25) BMI 44.3
CW 15st
GW1 15st (03/01/26) BMI 34.6
GW2 13st
Total loss- 59lbs.

Kazzaa46 · 07/01/2026 09:46

SnowWhiteisMyFavourite · 07/01/2026 07:40

@Kazzaa46 I’ve used syringes with bigger needle for the golden dose and I have always inserted the needle fully into my skin. I do have a very big belly roll so I haven’t even thought about this being an issue 😄

Thank you. ☺️
I did try my first GD this morning, it was a massive fail 🤣 the syringe had lots of air bubbles which I think I got rid of but then I had trouble piercing the skin with the needle. I think I may have blunted it slightly hitting the plunger. I got so anxious I gave up and have started a new pen instead.
Honestly I say to myself- why are you like this 🙈

OneDayIWillLearn · 07/01/2026 13:08

@Kazzaa46 you have to press a bit harder with the insulin syringes to get them through the skin as they are slightly thicker but they do go in and I don’t find they really hurt any more once in. I think I push the needle in half to 3/4 of the way when I use them but I don't think it would make too much difference how far as long as they are through the skin!

Atalosswhat2do · 08/01/2026 10:51

I hope you are all having a good week! A 1.7lb loss this week takes me to just under 7lb to go until I hit my 1st target of 9st 1lb. 🥳

Week 17 results:

SW: 12st 3lb
CW: 9st 7.8lb
GW: 9st 1lb

Week 1: -6lb
Week 2: -2lb
Week 3: -1lb
Week 4: -2lb
Week 5: -3lb
Week 6: -2lb
Week 7: -0.5lb
Week 8: -1.2lb
Week 9: -1.4lb
Week 10: -3.6lb
Week 11: -3.1lb
Week 12: -0.3lb
Week 13: -2.9lb
Week 14: -1.8lb
Week 15: -3lb
Week 16: -1.7lb
Week 17: -1.7lb

Total Loss: 2st 9.2lb

Good luck to everyone weighing and jabbing this week!

Ihateslugs · 08/01/2026 12:37

Heres an update for you re my knee replacement surgery!

Everything went well and I came home on the 18th Dec after 2 nights in hospital. I was given the same pain meds as I was taking before my operation, Tramadol and paracetamol but upped the frequency to four times in 24 hours. I also had some oramorph for breakthrough pain in-between my other meds but that did nothing for me. They kept me in for an extra night as my blood oxygen levels were low.

Interestingly, I was on medication for high blood pressure before the surgery but my blood pressure is now low without taking any of the medication! As first it was “blamed” on the anaesthetics used but its continued to be low since I came home.

Food wise, I did not have much appetite for about a week but it’s back to normal now, I’m not taking Mounjaro though as I still need to discuss a date for knee surgery on my other leg so no point in starting again on a low dose only to have to stop again 6 weeks prior to the operation. As you might remember, I had bad diarrhea after every injection ( was on it for 12 weeks) so had discussed changing to a different WLI with the pharmacist but he said that all the injections
have diarrhea as a side effect so I need to think what to do. I am struggling a bit to regulate what I eat but that is partly due to my difficulties in cooking fresh meals while hobbling around in pain on two crutches! So I’ve eaten some high cal snacks because it was easier!

However, I’m now 3 weeks post surgery and progressing quite well, still taking maximum pain meds but able to weight bear on the operated leg which makes life a lot easier. I can keep pain levels to a bearable level most of the time although there are times when it really hurts, possibly after too much exercise as it gets swollen then. Ice packs are good though to reduce the swelling. I’ve not ventured outside yet apart from a trip back to the hospital to have the staples out - that hurt! My wound is being slow to heal and the scab looks a mess with still some bleeding but as I’m on blood thinners following a TIA in 2021 I do bleed a lot!

I had to inject with blood thinners twice a day for 14 days but I was a pro at that as they were single use pens just like the Mounjaro pens with the same very thin needles. The only problem was the dose was a lot more and it stung a little after the injection. However, i was told to only inject in the stomach and I had the most awful bruises and almost ran out of “fresh” skin to inject in! The nurses though were impressed on my injecting skills!

Weight wise, I cannot actually stand upright on the scales to get an accurate reading although I’m going to try again over the weekend. I suspect I have gained a little as at one point I was eating high salt foods like crisps and peanuts to try to raise my blood pressure but I’ve given up having them now. I will go back to my intermittent fasting regime very soon now that I can cook a little, I’m planning to make a batch of mushroom soup later today which will be a good start.

Im very bored though stuck in the house on my own so it’s very tempting to snack a lot but I’ll just stop buying the wrong things now Christmas is over! I do have a visit to the torture chamber aka physiotherapist to look forward to later this afternoon. As I cannot drive that means a taxi which will be fun as getting into a car is somewhat challenging when it hurts so much to bend your leg!

Bugling · 08/01/2026 17:40

Haven’t been on here for a few weeks, I had a Christmas break and didn’t inject from mid December. Not because I particularly wanted to eat loads but I did not want to suffer side effects. I don’t like Christmas Cake, Pudding or mince pies and I’m not that fussed with chocolate but I did want my cheese, ham and Christmas dinner and wine 😀

Suprisingly I continued to not want anything like as much food as I would have previously, even after 3 weeks. It wasn’t the same as being on them but still I ate less. I jabbed again on New Year’s Day and after a couple of days whem the general bloating had gone I only weighed in at 1lb more, and today I’m 3lb down. I hit my 2 stone mark and am ready to get losing again! I have two milestones, I would like to be down a stone and a half by my March birthday, and at goal whem we go away to the South of France in August. It’s the whole extended family and there a pool and hot tub etc so want to feel happy to breeze about in swimsuit and wrap etc! My goal isn’t a set weight, just when I’m happy! I’ve never been skinny skinny so I’m not aiming for an 8-10 kind of size. I have boobs and a bum and want to keep them!

I’ve been very good with my protein and salads this week, which I had struggled with! I also got a walking/running treadmill which slides under the sofa, did a 5K while watching TV today! I managed more running than fast walking which I’m pleased with, I have to remember in August I was struggling with walking long distances! Which was what made me do this.

does anyone feel a difference between stomach and leg injections? I tend to do my thigh but I’d read some people find stomach gives better suppression?

SW Sept 10th - 16 stone 4
CW Jan 8th - 14 stone 3

September 25 starters - new year, new trousers.
September 25 starters - new year, new trousers.
Chopsy123 · 08/01/2026 22:26

@Ihateslugs Wow, you’re doing so well after your OP. 👏👏.

I’m glad you’re still keeping us updated with your progress.

GhostOrchid · 09/01/2026 09:46

A slight gain for me this week - about 1lb - but I’m not too surprised. I had a very stressful day at work yesterday. A very long day on my feet, lots of moving parts and last minute change of plans, people to deal with etc. All went well in the end, but I was fuelled by carbs and sugar. I had a Pret chicken sandwich, crisps, biscuits, a couple of chocolates and then a gin and tonic after it was all over. I knew I didn’t really need the biscuits or chocolates but they were a way of dealing with the stress of the day and helping keep my energy up. Slightly unfortunate timing that it was a day before my jab day.

Also, after strong suppression over the weekend, it waned quite badly the last few days and I've felt quite a lot of hunger and the food noise was back. I’ve got two doses left in my 5mg pen. I was hoping to stay on 5mg for a bit longer but maybe it’s time to go up.

Also dinner with friends tonight and a curry tomorrow. Bloody January birthdays.