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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

December 25 starters thread?

831 replies

cobblers00 · 28/11/2025 09:39

Is there one yet? If not, should this be it? I’m starting tonight, so officially November, but hey! Am so nervous, woke up early this morning with anxiety. Would love tips from anyone who has started before on what / how to eat on first few days..I’m really concerned about debilitating side effects- should you just listen to your body or force yourself to eat chicken?! I keep seeing all these insta posts about eating protein!!

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cobblers00 · 21/01/2026 10:28

So had a right disaster trying to extract the golden dose! I think I did it too quickly as it only extracted a small amount leaving a huge air bubble. So I tried again with the remaining amount but that only measured .4 and wasn’t sure if had tiny air bubbles in it so got cold feet and squirted the lot down the sink!!! Started on new pen now so will have to try it with this one, more slowly. I believe air bubbles aren’t a problem as you’re injecting into fat, right? I didn’t want to risk it though.

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Florrieboo · 21/01/2026 19:45

I did my final weigh in yesterday and in 5 weeks I lost 7kg or just over a stone. I am really happy with that and even though I have had to stop for now I am a stone lighter than I was before Christmas and that is a good thing.

Colinthedaxi · 21/01/2026 21:09

cobblers00 · 21/01/2026 10:28

So had a right disaster trying to extract the golden dose! I think I did it too quickly as it only extracted a small amount leaving a huge air bubble. So I tried again with the remaining amount but that only measured .4 and wasn’t sure if had tiny air bubbles in it so got cold feet and squirted the lot down the sink!!! Started on new pen now so will have to try it with this one, more slowly. I believe air bubbles aren’t a problem as you’re injecting into fat, right? I didn’t want to risk it though.

That’s exactly what happened with me, I was flustered but I inject horses so I’m not usually an absolute muppet with needles. Will try again next time 🤞

Lovingthelighterevenings · 22/01/2026 22:02

I just extracted the last dose from my second pen (not sure what I was thinking but I ordered the wrong size syringes so had to use two...). But I'm down 6 kg in 10 weeks so happy with that. I'm not sure I'll believe it until get past my psychological breakthrough weight.

Still haven't got my meals in line - I'm not hungry at lunch so I'm just grabbing an apple. But I'm getting a protein dense (for me at least) breakfast.

Ramblingnamechanger · 23/01/2026 11:32

3 weeks in…no effects till this week and now lots of unpleasant burping, and diarrhea, after some bloating and constipation, woke up dreaming that I was poisoning myself . I don’t want it to work only because I am ill and as I will be travelling long haul for six weeks really thinking of stopping. I did have good initial results from diabetes 2 medication…but had plateaued so keen to try MJ. I have a few days before seeing the doctor, but not sure whether to take the last dosE. BMi 35, good diet , swim twice a week, walk most days, over 70. Not really fancying food which I usually used to enjoy,so not feeling I can have a nice life. Seem to have lost the kilo I put on over the Xmas period.

StrongGirlsLift · 23/01/2026 18:21

That sounds tough @Ramblingnamechanger, hope you feel better soon.

I have had a poor few days of eating - it’s been so busy I haven’t eaten all that much and it’s been quite carb-heavy. I feel awful for it today - sickly and full of burps and heartburn. Must do better! I’m due to go up a dose tonight too.

Also: for what I think is the first time ever, I had what looks like a Raynaud’s attack - fully white and frozen fingers on each hand. I haven’t had this any other time at this weight (still overweight). Apparently, weight loss and stress and cold are factors. Not fun.

Florrieboo · 23/01/2026 19:15

I was due to take my 6th dose last Tuesday so 4 days ago now and didn't because I had to stop but my appetite has not come back yet. It is very strange, I have no interest in food at all. I wonder how long I can ride on the coat tails of this for?

SexyFrenchDepression · 23/01/2026 20:00

Florrieboo · 23/01/2026 19:15

I was due to take my 6th dose last Tuesday so 4 days ago now and didn't because I had to stop but my appetite has not come back yet. It is very strange, I have no interest in food at all. I wonder how long I can ride on the coat tails of this for?

It will still be in your system, according to the shotsy graphs you reduce by about 0.2mg per day, so will depend on what dose you were on and how much had built up in your system. Hopefully you should have a little while left of it working. Plus you would be used to eating a lot less so hopefully your body has adapted a bit (I am hoping thats true haha)

cobblers00 · 23/01/2026 20:01

Were you on 5mg @Florrieboo ? I’m still on 2.5 & my appetite is pretty good- to the point that when I do get hungry i feel pretty ravenous, then full quickly. But similar to you @StrongGirlsLift I’ve not ate well today, in fact just had a small pack of frazzles & a choc digestive after my dinner of 3 turkey sausages! I couldn’t be bothered to cook & honestly if someone had put a dominoes pizza in front of me I’d have dug in, so that initial repulsion towards bad foods is wearing off. Really don’t want to go up a dose tho!! I did take this week’s 6 days apart & will keep doing that for this pen. Weigh in tomorrow.. let’s see if it’s 3 weeks without budging. Hope not.

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SexyFrenchDepression · 23/01/2026 20:03

@Florrieboo l have just checked my shotsy app. I have been on 2.5mg since 1st November (had 3.75mg x 3 in the middle) then back to 2.5mg but only 1.67 on weds (as ran out in that pen) however it will be 24th Feb before there is 0 in my system.

cobblers00 · 23/01/2026 20:06

SexyFrenchDepression · 23/01/2026 20:03

@Florrieboo l have just checked my shotsy app. I have been on 2.5mg since 1st November (had 3.75mg x 3 in the middle) then back to 2.5mg but only 1.67 on weds (as ran out in that pen) however it will be 24th Feb before there is 0 in my system.

This is interesting.
why did you go down after 3wks on 3.75 @SexyFrenchDepression?

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SexyFrenchDepression · 23/01/2026 20:09

cobblers00 · 23/01/2026 20:06

This is interesting.
why did you go down after 3wks on 3.75 @SexyFrenchDepression?

TBH I didnt really need to go up but had bought a 5mg pen, I didnt have much appetite on 2.5 as it was but also then I got sinusitis and it was making me feel so sick so I went down to 2.5 again to see if that helped and just stuck with that.

New pen next week so will try 2.5mg and see if it works ok, I'll increase it if not.

Florrieboo · 23/01/2026 20:15

I never went over 2.5

SexyFrenchDepression · 23/01/2026 20:31

Florrieboo · 23/01/2026 20:15

I never went over 2.5

So I looked back and on day 7 after jab 5 there was about 1.9mg left in my system (I'd only taken 2.5mg at that point). So that would mean at this point you have just over 1mg left in your system so around 4/5 more days till its gone I think.

cobblers00 · 24/01/2026 08:11

Morning all, disappointed scales barely moved again from last two weeks - down .5 of a kilo… def not been exceeding my defecit intake but have been strength training more so could be that. Also not done a big poo for days 😂.. I think I’m going to stay off the scales for longer periods as it is quite disheartening when everything else feels like the weight is coming off.
how’s everyone else doing?

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cobblers00 · 24/01/2026 08:11

Morning all, disappointed scales barely moved again from last two weeks - down .5 of a kilo… def not been exceeding my defecit intake but have been strength training more so could be that. Also not done a big poo for days 😂.. I think I’m going to stay off the scales for longer periods as it is quite disheartening when everything else feels like the weight is coming off.
how’s everyone else doing?

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cobblers00 · 24/01/2026 08:11

Morning all, disappointed scales barely moved again from last two weeks - down .5 of a kilo… def not been exceeding my defecit intake but have been strength training more so could be that. Also not done a big poo for days 😂.. I think I’m going to stay off the scales for longer periods as it is quite disheartening when everything else feels like the weight is coming off.
how’s everyone else doing?

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StrongGirlsLift · 24/01/2026 08:44

@cobblers00 I prescribe more water! It’s coming off, and it sounds like you may have a bit of inflammation from weight training.

I know I always put about a pound back on if I train intensively in the evening, especially cardio. It is so frustrating through the plateau phases, isn’t it!

I need to get up and weigh/measure/inject. I didn’t inject last night as I felt a bit rough, but my stomach has settled now. I’m going to eat as clean as possible today!

StrongGirlsLift · 24/01/2026 09:01

Weigh in for me:
SW: 74kg
CW: 68.9kg
GW: 55kg?

So far, 3 inches off my waist, one off my hips, arms exactly the same and one thigh is 1 inch bigger (a victory as I am rehabbing an injury and working hard on building back muscle!)

Slow, but steady and all in the right direction. I’ve lost 6.6% of my body weight in 2 months, so as I keep going that will be 15-20% in 6 months. I’m ok with that and I’m only just hitting what they describe as “active dose” (1mg WG) with today’s injection.

How’s everyone doing, will we keep on keeping on? (Those of us who haven’t had to stop for other reasons I mean).

StrongGirlsLift · 24/01/2026 09:13

Oh an my blood pressure has dropped into the top of the healthy range, yey!

Margaritawithlime · 24/01/2026 09:26

Morning all! Big whoosh from me and dropped 4:5lbs this week. 26 in total. I’ve lost 3 inches around my waist, 2 from my hips, 1 from my arm and 1 from my calf. Staying on 5mg this next month and managed golden dose successfully from my pen this time! Feel full of energy in general and sleeping much better.

StrongGirlsLift · 24/01/2026 09:38

That’s outstanding @Margaritawithlime, well done you and great that you’re feeling good on it!

cobblers00 · 24/01/2026 12:28

Well done @Margaritawithlime& @StrongGirlsLift- great progress. I will take your advice & drink even more water & see if that helps! I’m waiting for the big whoosh on the scales as honestly feel so much slimmer but the scales just dont seem to tell the same story!!! I’ve lost 2inches off thighs & 4 off waist. Don’t measure hips as can’t work out where to do it in same place each time!! But they are def slimmer as none of my jeans fit properly now. I think I’m going to get down to 62kg or a size 10- whichever comes first! Currently a 14- started out 16 & tight.
I feel 100% better in myself than before starting WLI- only thing I do get is a bit light headed day or so after jabbing. But otherwise full of energy & no intention of stopping. I can’t imagine eating all the crap I did before & really hope can hold on to this mindset without the medication.

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SexyFrenchDepression · 24/01/2026 12:47

cobblers00 · 24/01/2026 12:28

Well done @Margaritawithlime& @StrongGirlsLift- great progress. I will take your advice & drink even more water & see if that helps! I’m waiting for the big whoosh on the scales as honestly feel so much slimmer but the scales just dont seem to tell the same story!!! I’ve lost 2inches off thighs & 4 off waist. Don’t measure hips as can’t work out where to do it in same place each time!! But they are def slimmer as none of my jeans fit properly now. I think I’m going to get down to 62kg or a size 10- whichever comes first! Currently a 14- started out 16 & tight.
I feel 100% better in myself than before starting WLI- only thing I do get is a bit light headed day or so after jabbing. But otherwise full of energy & no intention of stopping. I can’t imagine eating all the crap I did before & really hope can hold on to this mindset without the medication.

I am the other way round right now, haven't felt like I've got thinner, in fact felt bloated today but still losing. I wish I had done measurements also.

I do feel thinner at this weight than I did before. Weighed in at 9st12.8 today and it was definitely top end of my fat weight 6 or so years ago and I would hide under loose clothes then. I imagine its because I am used to being fatter whereas before it would be a lot over what I was used to (plus my clothes have probably got gradually bigger so they feel more comfortable now). BMI is 23.8 currently which I'm pleased about. 12.8lb to go till target, but most importantly I need to ensure I am exercising more as my habits regarding that have become awful lately.

ChristmasCalsDoCount · 24/01/2026 20:06

If anyone is looking to switch providers I have a code for £100 off with Numan

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