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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Really want to start MJ

88 replies

strawberry780 · 15/11/2025 20:37

Hi all ,
really want to start weight loss injections but so scared of the side effects.
did anybody have any side effects if so what did you have?
I was put on sertraline a year ago and in a year I’ve gone from 10stone to 14. Feel absolutely miserable

OP posts:
maz99 · 27/06/2026 11:37

OneCheekyDeer · 27/06/2026 08:26

I have been refused WLI due to gallstones (I have very little bother from them). Apparently taking WLI could lead to pancreatitis which is a medical emergency and potentially life threatening. I am considering other options now.

Pancreatitis is known as one of the more serious side effects of GLP1, which is why a medical history is requested when you register with a pharmacy.

Having gallstones could make you a higher risk, but you may could still get GLP1 if you tried a pharmacy that offers 1 to 1 consultations (Lotus, Medicine Marketplace, etc.)

Because you can then explain if you've successfully managing your gallstones.

Thebigonesgetaway · 27/06/2026 12:20

maz99 · 27/06/2026 11:37

Pancreatitis is known as one of the more serious side effects of GLP1, which is why a medical history is requested when you register with a pharmacy.

Having gallstones could make you a higher risk, but you may could still get GLP1 if you tried a pharmacy that offers 1 to 1 consultations (Lotus, Medicine Marketplace, etc.)

Because you can then explain if you've successfully managing your gallstones.

Please don’t post misinformation.

https://ascopubs.org/doi/10.1200/JCO.2026.44.2_suppl.712
https://journals.lww.com/ajg/fulltext/2024/10001/s5_glp_1_receptor_agonists_and_pancreatic_cancer.6.aspx
https://www.dailymail.com/health/article-15879295/pancreatic-cancer-remarkable-link-mounjaro-fat-jabs.html

The remarkable link between Mounjaro and pancreatic cancer revealed

It is one of the most brutal cancers, killing around three-quarters of those diagnosed within a year. And, perhaps even more worryingly, it is on the rise.

https://www.dailymail.com/health/article-15879295/pancreatic-cancer-remarkable-link-mounjaro-fat-jabs.html

maz99 · 27/06/2026 13:39

So you post a link and don't explain your point - what part of what I said was misinformation?

Pancreatitis and pancreatic cancer are NOT the same thing.

Maybe you should take your own advice.

Really want to start MJ
Really want to start MJ
cloudjumper · 27/06/2026 14:52

I felt really cold in the first few weeks, but that passed. I’ve only had constipation as a side effect, which is well known, and would sometimes resort to some mild laxatives to help things along.
But I have lost over 5 st within a year, which has had such massive impact on my quality of life.

Spoileralwrt · 28/06/2026 07:27

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Peony1985 · 09/07/2026 22:52

Theres always going to be more research into what causes the side effects. I drink loads on WLI but don’t feel hungry. I also eat little processed food. So actually it’s likely to be alcohol if I get pancreatic problems same as someone who loses weight but eat shite.
I think all cancer risks reduce for skinny people ( aside from specific risk cancers like skin or lung from sun and smoke )

Icanthinkformyselfthanks · 09/07/2026 23:11

@strawberry780 , the very few side effects I had were easily manageable. I am so grateful that before I died I could feel the peace they have given me and the joy I have experienced from the weight loss. I was so worried to start but it has been the best thing I’ve ever done for myself. Try, you’re most like to find it ok but what if you don’t try? One course will completely change your life for the better, the other is more unhappiness. A bit of a no brainer in my opinion, shake it and see, what really is the worst that can happen?

Pistachiocake · 09/07/2026 23:29

Ineedanewsofa · 15/11/2025 21:53

A couple of bouts of constipation, solved by using sennakot and reducing the supplements I was taking.
One occasion of an irritated injection site, I think I accidentally blunted the needle on the cap before injecting.
Bloating and discomfort if I over consume heavy carbs like pizza - so I don’t any more!
Also cold a lot of the time now.
I’m 20kg down in 5 months, still on 2.5mg and feel the best I’ve felt in years. My inflammation related issues (tendinitis, carpal tunnel) disappeared within 4 weeks of starting and have not returned which has been worth it even if I hadn’t lost the weight

What dose must you take for joint pain/inflammation to go please? Because even if someone has a BMI of 25, would it be worth it for them to try it?
We all know lots of drugs are used not for their original purpose, but if it means a person could get back to exercising, isn't that as good for health as a person who needs to lose weight using it?

Ineedanewsofa · 10/07/2026 08:19

Pistachiocake · 09/07/2026 23:29

What dose must you take for joint pain/inflammation to go please? Because even if someone has a BMI of 25, would it be worth it for them to try it?
We all know lots of drugs are used not for their original purpose, but if it means a person could get back to exercising, isn't that as good for health as a person who needs to lose weight using it?

I’m not a Dr or a pharmacist so can’t say, I however am now 30kgs down in 12 months and have seen no return of joint or nerve pain and inflammation. I’m still on 2.5mg, never gone higher.
I believe some pharmacies will prescribe off label at a lower BMI (25-27)

Jogonpolly · 10/07/2026 09:20

Pistachiocake · 09/07/2026 23:29

What dose must you take for joint pain/inflammation to go please? Because even if someone has a BMI of 25, would it be worth it for them to try it?
We all know lots of drugs are used not for their original purpose, but if it means a person could get back to exercising, isn't that as good for health as a person who needs to lose weight using it?

For DH, his inflammation - so snoring, joint pain and such reduced drastically after his very first dose.

MeridaBrave · 10/07/2026 11:37

Pistachiocake · 09/07/2026 23:29

What dose must you take for joint pain/inflammation to go please? Because even if someone has a BMI of 25, would it be worth it for them to try it?
We all know lots of drugs are used not for their original purpose, but if it means a person could get back to exercising, isn't that as good for health as a person who needs to lose weight using it?

I guess I would try at half the starter dose ie 1.25mg and see if it helps?

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