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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Really want to start MJ

74 replies

strawberry780 · 15/11/2025 20:37

Hi all ,
really want to start weight loss injections but so scared of the side effects.
did anybody have any side effects if so what did you have?
I was put on sertraline a year ago and in a year I’ve gone from 10stone to 14. Feel absolutely miserable

OP posts:
DBatteryBand · 16/11/2025 07:23

Hardly any side effects for me. Some nausea when moving up a dose, but nothing a cup of mint tea wouldn't fix. Suppression can be a bit tricky, I've had a few mornings of sitting there looking sadly at my breakfast, and once it took me half an hour to eat half a boiled egg (again, that was the week I moved up to 7.5mg) but it's been fine. I really understand your reluctance, but you start on a low dose and can stop at any time.

Thebigonesgetaway · 16/11/2025 07:44

Elliebearblues · 16/11/2025 00:50

Everyone experiences different side effects, I’ve had nausea, stomach cramps, Diorrhea, dizziness and sulfer burns, not all the same time.. it dosnt help I came down with a stomach bug about 4 weeks ago and then got this nasty cough which I’ve had the last 2 weeks so I think my immune system is weak, I’m still going though x

Everyone doesn’t. 80 percent of people have no side effects.

Batoutofhellish · 16/11/2025 07:50

I feel the same . Robbie Williams is in the news saying it’s ruined his eyesight which makes me panic. The hair loss also worries me.

SilenceInside · 16/11/2025 07:58

Nothing Robbie Williams says would worry me, he’s a pop star not a medical expert, and he has had his eyes checked and just needs glasses. Which at 51 is hardly unusual. Nothing in what he has said indicates it was caused by taking Mounjaro.

Hair loss, if it happens, is temporary and resolved itself. It can also happen on any kind of diet. The health risks of being obese outweigh the potential for hair loss, imo.

MeridaBrave · 16/11/2025 08:03

SilenceInside · 16/11/2025 07:58

Nothing Robbie Williams says would worry me, he’s a pop star not a medical expert, and he has had his eyes checked and just needs glasses. Which at 51 is hardly unusual. Nothing in what he has said indicates it was caused by taking Mounjaro.

Hair loss, if it happens, is temporary and resolved itself. It can also happen on any kind of diet. The health risks of being obese outweigh the potential for hair loss, imo.

Totally normal at 51 to become long sighted, often quite suddenly.

MiniCoopers · 16/11/2025 08:04

I did get gallstones and need my gallbladder removed but I fell into the category of that likely happening anyway. I restarted MJ 6 months after my op and have been fine since.

Sweetiedarling7 · 16/11/2025 08:11

I have been on mounjaro a year, gone right up to 15 mg and never had any side effects except transient mild constipation which was easily managed with some stewed fruit and occasional dose of lactulose.
I know four other people in real life on mounjaro and none have had any side effects.
You can get a very distorted view reading horror stories on social media because for everyone who posts about their terrible side effects there will be twenty people saying nothing because they have no problem.

monjmaintainer · 16/11/2025 08:41

My side effects were super mild. Some queasiness the first couple of months but never actually sick. Realised it tended to be when stomach empty and easily resolved. Eat clean a couple of days before you start - avoid fried, fatty or stodgy white carb foods to make it even less likely.

I think you hear the bad stuff more as people come online to talk about it as they often can’t in real life which is understandable and of course it’s possible you will be one of the unlucky few but much more likely you won’t and really benefit. As someone else said you won’t know until you try and can always stop. There are some good deals right now for a 2.5mg pen and if you are really scared then you could even do first week or 2 on half doses just to check you don’t react badly. (The prescriber won’t tell you that as it’s not a listed method but people do it - they just take half the clicks - 30 instead of 60).

good luck if you decide to go for it - so much amazing support on this board 🙂

Batoutofhellish · 16/11/2025 08:45

Hair loss is a well documented side effect though.

Lightswitchy · 16/11/2025 08:51

I think if you can lose the weight without mj that would be better.
if you do believe sertraline to be the problem then you can taper off or switch medicine.
everyone responds differently to medication i know of people who have lost weight whilst taking sertraline.
the only thing is if you start taking mj you will have to keep taking it for it to work, this has financial obligations.
also in my view, i believe that the reason people lose weight on these GLP-1 medications only lose weight because they feel so sick and lousy to be able to eat!
Thermodynamics is a thing look it up.
also what is your height ? Do you have a lit of muscle? So many factors to consider here

SilenceInside · 16/11/2025 08:55

@Lightswitchy it is just not true that the only reason people lose weight is that they feel too sick to be able to eat. I’ve been on Mounjaro for almost a year and a half. After the initial few weeks I haven’t had any side effects at all. I don’t feel sick, or unwell or nauseous or anything like that. I just have less interest in food and can stick to a calorie deficit. And, as I’ve lost 10 and a half stone, I feel so much healthier and fitter than I did before.

MeridaBrave · 16/11/2025 09:00

SilenceInside · 16/11/2025 08:55

@Lightswitchy it is just not true that the only reason people lose weight is that they feel too sick to be able to eat. I’ve been on Mounjaro for almost a year and a half. After the initial few weeks I haven’t had any side effects at all. I don’t feel sick, or unwell or nauseous or anything like that. I just have less interest in food and can stick to a calorie deficit. And, as I’ve lost 10 and a half stone, I feel so much healthier and fitter than I did before.

I’ve not felt sick or nauseous at all. I’ve mostly felt full for longer, and not really experienced hunger.

Thebigonesgetaway · 16/11/2025 09:05

Lightswitchy · 16/11/2025 08:51

I think if you can lose the weight without mj that would be better.
if you do believe sertraline to be the problem then you can taper off or switch medicine.
everyone responds differently to medication i know of people who have lost weight whilst taking sertraline.
the only thing is if you start taking mj you will have to keep taking it for it to work, this has financial obligations.
also in my view, i believe that the reason people lose weight on these GLP-1 medications only lose weight because they feel so sick and lousy to be able to eat!
Thermodynamics is a thing look it up.
also what is your height ? Do you have a lit of muscle? So many factors to consider here

That’s such nonsense, even reading the thread before you posted would have shown your it’s nonsense. I also never had any side effects, as 80 percent of people didn’t in trials and real life data shows the same.

and of course you need to keep taking it for it to work, who on earth would think there is a drug that works if you don’t take it. It’s not surgery lol.

reluctantbrit · 16/11/2025 09:27

I had a bit of nausea at the beginning and when I moved to 5mg. I also learned fast that I have to stop eating most shop bought bread. Fresh or self-baked work but not the packed variety.

I am also not great with anything fatty or deep fried but I think that's just a good thing.

Otherwise my worst side effect is constipation.

MeridaBrave · 16/11/2025 09:33

Lightswitchy · 16/11/2025 08:51

I think if you can lose the weight without mj that would be better.
if you do believe sertraline to be the problem then you can taper off or switch medicine.
everyone responds differently to medication i know of people who have lost weight whilst taking sertraline.
the only thing is if you start taking mj you will have to keep taking it for it to work, this has financial obligations.
also in my view, i believe that the reason people lose weight on these GLP-1 medications only lose weight because they feel so sick and lousy to be able to eat!
Thermodynamics is a thing look it up.
also what is your height ? Do you have a lit of muscle? So many factors to consider here

Re: taking long term. This will vary. Some people may be able to take on new good habits, build muscle mass, adopt an effective approach to exercise etc and manage to maintain their weight without.

Others will not manage this and will need to take longer term. I envisage periods on and periods off. I’ve managed to maintain in short term before but not longer term.

monjmaintainer · 16/11/2025 09:51

Lightswitchy · 16/11/2025 08:51

I think if you can lose the weight without mj that would be better.
if you do believe sertraline to be the problem then you can taper off or switch medicine.
everyone responds differently to medication i know of people who have lost weight whilst taking sertraline.
the only thing is if you start taking mj you will have to keep taking it for it to work, this has financial obligations.
also in my view, i believe that the reason people lose weight on these GLP-1 medications only lose weight because they feel so sick and lousy to be able to eat!
Thermodynamics is a thing look it up.
also what is your height ? Do you have a lit of muscle? So many factors to consider here

What a well thought out post… 🤣 yes we’ve all lost weight as we feel too sick to eat. I eat better than I have in my entire adult life. Healthy nutritious meals. Just fewer calories and a lot less crap.

Also it’s very impressive that you understand the laws of thermodynamics in the context of metabolism so well as this is an area of significant research. Even 20 years ago biochemists came to this conclusion - “The second law of thermodynamics says that variation of efficiency for different metabolic pathways is to be expected. Thus, ironically the dictum that a "calorie is a calorie" violates the second law of thermodynamics, as a matter of principle.”

https://pmc.ncbi.nlm.nih.gov/articles/PMC506782/

"A calorie is a calorie" violates the second law of thermodynamics - PMC

The principle of "a calorie is a calorie," that weight change in hypocaloric diets is independent of macronutrient composition, is widely held in the popular and technical literature, and is frequently justified by appeal to the laws of ...

https://pmc.ncbi.nlm.nih.gov/articles/PMC506782/

MeridaBrave · 16/11/2025 10:01

strawberry780 · 16/11/2025 03:21

I have severe emetophobia thats why I asked about it

So I would start with 15clicks on week 1 (1/4 starter dose). If that goes ok do 30 on week 2 and 45 three. If that’s all good can increase to 60 (full dose)

Lightswitchy · 16/11/2025 10:34

Like i said there may be other ways to lose weight rather then resulting to putting another chemical in your body that could cause sickness. The people who are getting defensive about mj are the ones justifying there usage. Just please consider all your options before taking

Lightswitchy · 16/11/2025 10:35

And above all, consult with your GP!!x

strawberry780 · 16/11/2025 10:50

Lightswitchy · 16/11/2025 10:35

And above all, consult with your GP!!x

Thank you xx

OP posts:
monjmaintainer · 16/11/2025 10:56

It’s a bit disingenuous to jump onto a thread in the WLI board where someone is asking for information because they want to start, to give an uninformed opinion that we all lost the weight as we were too sick to eat. Also unless the OP is one of a very lucky minority it’s improbable her GP will be willing to discuss or provide ongoing support with this. Hence why we all turn to forums like this to speak to those who have experience. But also run the risk of attracting the classic eat less move more posters sticking their unwanted opinions in.

It’s absolutely wise to take your time over the decision OP and do a lot of research - it took me several months to make the decision. You will find lots of support on these boards. WLI are not for everyone but there is no doubt that they are proving life changing for millions and will have the biggest long term health impact we’ve seen in generations.

NikkiPotnick · 16/11/2025 11:00

Lightswitchy · 16/11/2025 10:34

Like i said there may be other ways to lose weight rather then resulting to putting another chemical in your body that could cause sickness. The people who are getting defensive about mj are the ones justifying there usage. Just please consider all your options before taking

The posts about your nonsense are more attacking than defensive, and rightly so. If you want to advise people to carefully consider all their options, you can do that before making things up.

Branleuse · 16/11/2025 11:10

I get some side effects, but i find them manageable.

Theres been a few times when ive gone up a dose where i get weird dry mouth and gassy for a day or two.

I think if you take it slowly, its better

curious79 · 16/11/2025 11:13

Everyone is really different both in terms of the side effects they have and their willingness to put up with those side effects.

I tried ozempic and found it gave me headaches and I felt massively sick all the time. I then tried Mounjaro and had an allergic reaction to it.

I’ve spoken to some friends who are on ozempic and they talk about constantly having headaches and having to just work through the feeling sick. But I can’t stand feeling like that on a day-to-day basis. It’s not something I want to get used to. I know people who are losing HAIR. They also look much older.

my fear is that it causes muscle wastage, and that includes the heart muscle, so I’m glad for it not to work in some ways for me

Instead, since then I’ve gone on the Human Being Diet, lost 4 stone, and feel no cravings whatsoever

Lightswitchy · 16/11/2025 11:21

NikkiPotnick · 16/11/2025 11:00

The posts about your nonsense are more attacking than defensive, and rightly so. If you want to advise people to carefully consider all their options, you can do that before making things up.

If you feel “attacked” by my valid point and opinion maybe you should look into why you feel like this rather then putting the onus on me personally!
you dont know my experiences, and I'm allowed to have opinions! Taking all this into account is how people create informed decicions. Which your claming to be an advicate of! Good for you 💐

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