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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

On it for life then.........😐

317 replies

Ihavesomeballs · 08/11/2025 15:39

I've lost 11kg on Mounjaro. I wasn't obese to start with but I'm tiny, 5ft 1 inch. I'm now just in the healthy weight BMI. I stopped my 5mg dose for 3 weeks as I had to wait till payday to order my next pen. In that time I wasn't eating any more than usual but I put on 2kg. So I guess I'm on it for life......which sucks as it's bloody expensive. Anyone else??

OP posts:
Hippobot · 09/11/2025 21:26

SilenceInside · 09/11/2025 21:16

@Hippobot I asked how you knew what you were asserting, not who told you. And it is a grandiose claim, whether it’s true or not, and I hope you can understand why people shouldn’t take what’s claimed online by anonymous posters at face value.

It’s also an appeal to authority, not an explanation of how you know what you were asserting. It’s not a valid explanation. And I would expect a leading global expert on WLI to not pass on unevidenced claims about what she or he is researching.

But that's how I know - because he's been through the research and the science of it with me. I'm a fat bastard by the way and taking the injections would have been an easy move for me so I had the discussion with him and on balance decided, it's not worth the risks that he went over with me. I'm very sorry it doesn't pass the strict Mumsnet test for who's opinion is okay for this post but that's the reality of my experience. I'm sorry I ever shared it now.

arcticpandas · 09/11/2025 21:26

SilenceInside · 09/11/2025 20:02

Yes, Mounjaro is approved for long term maintenance.

It hasn't been tested for longtime use though for obesity treatment so who knows? It's an assumption It's safe.

RunSlowTalkFast · 09/11/2025 21:26

TheSlimmingPumpkin · 09/11/2025 21:20

I must have imagined those checks with Oushk and the verification calls I did.

oh well 🤷‍♀️

They're not all that strict. The ones I've been with just wanted a couple of photos. I'm only just in the obese category and this didn't do any other checks.

Ihavesomeballs · 09/11/2025 21:27

HansHolbein · 09/11/2025 21:09

Of course; always happy to share how life changing this has been for me.

Since the age of about 9, I started putting on weight. My parents and brother have always been at the low end of the BMI scale. My mother always made healthy, home cooked food. There was no UPF in our house. It was rather boring for snacks!

Anyway, my period started at the age of 12. I didn’t get it again for a few years - I think I was about 14/15 when it arrived again.

During this time, I was overweight, face full of acne, hairy face, snail trail, mental health very up and down. This unfortunately continued until I started MJ last October at the age of 34.

Since the age of 12, I’ve had about 10 periods. This made it very difficult for us to conceive, as you can imagine. I would continuously lose and regain about 5 stone. I can’t actually begin to tell you how being overweight and the associated symptoms of PCOS made me feel. Oh, such shame and self loathing. It was truly awful. So many missed opportunities and life experiences. So many times I’ve said no, when I wanted to say yes. How sad.

I knew about the injections in the summer of last year. I entered my stats in to all the usual providers many times, and then deleted it. Scared of the side effects, scared that this wouldn’t work either - so what was the point?

In September last year, I pretty much had a breakdown over it. My husband was amazing (he always is!) about it all, and was so sad about my suffering. Not to mention the concern around what a lack of a period can do to a woman’s body. He actually brought up the injections with me. He gave me the push. He said we didn’t have anything left to lose.

So, I started last October. Starting weight 102.8kg/16st 2.7lbs, BMI 38.2.

To my complete amazement, my period arrived in November. And it has done every month since then. That has never happened in my entire life.

By December, spots gone.

By January, mental health/anxiety issues, gone.

By around May, excess hair pretty much gone.

You could attribute some of these symptoms lessening due to weight loss, and that will absolutely be a factor, but that doesn’t explain how my period appeared since November. There is so much we don’t know about how MJ works positively in the body, alongside weight loss. I can’t wait to find out more.

I cannot begin to describe what this medicine has done for my body. My mind is now free. My body is truly free, working as it should.

I am now 8st, BMI 19. Been maintaining that easily for a couple of months.

I now say yes to everything. I don’t hate myself. I show up every single day in my new world and new body and can’t believe I get to live this life now. Free of all that torment and shame. I used to think there was something truly wrong with me. There is nothing wrong with me. I am perfect as I am, it’s just my body metabolically wasn’t working as it should. My poor body. All the horrible things I used to say to it.

Just like any other medication used to treat a metabolic/endocrine condition; MJ treats it as long as I keep taking it. If I stop, the symptoms come back.

I’ve not had any side effects, thank fully. I don’t have a gallbladder, it was removed some years ago.

This is just my personal experience, and it may not be the same for you. However, you could just try 2.5 and see what happens. You can always stop if you don’t like it, or it doesn’t work for you.

Plus, there are new medicines including in tablet form that are due to be released in the near future if you don’t like the thought of injecting.

If you do decide to try it, please find the monthly support group in here. I’ve met some amazing women, all lifting each other up without judgment. I’ve had a wonderful year and I am so excited about my life to come - freedom!

Best wishes.

Wow, wow and just wow. So happy for you! Brilliant post! 😁

OP posts:
LeBelleEpoque · 09/11/2025 21:29

Ihavesomeballs · 08/11/2025 18:53

I know I'm just worried that without the medication I'll be as heavy as I was without it. I kind of poo pooed the idea that I couldn't maintain my weight loss without the medication but it appears I can't. 😐

It’s only 3 weeks.

what other changes could you make? As others have said it’s not a ‘one and done’.

i’m the same height and I was obese prior to starting Mounjaro.

I’ve just lost a stone and am now ‘overweight’ with 2 more stone to go before I am within an OK BMi range for my height.

SilenceInside · 09/11/2025 21:29

@Hippobot the risks that your friend outlined to you are the same ones that we all are told about before making our own personal risk decisions. Not some additional knowledge of long term health damage that has yet to be published. Unless that’s what you’re claiming?

It is not stupid, naive, or poorly informed to make a different decision to you. The risks you listed are already known as rare side effects of this medication. Those are outlined before anyone is prescribed this medication. So to post about as yet unknown but severe long term health implications is simply scaremongering.

tommyhoundmum · 09/11/2025 21:30

StrongLikeMamma · 08/11/2025 15:51

It’s insane how few calories we actually need to eat isn’t it?!

Yes, I was so disappointed to be told I needed only 1250 when I have a really busy active life.

Hippobot · 09/11/2025 21:31

SilenceInside · 09/11/2025 20:52

Oh you can have an opinion @Hippobot but if you’re happy to post it then you should expect people to consider it and analyse its worth. And of course some people will doubt grandiose claims, especially when they are making an appeal to authority against the prevailing science.

How about you just analyse and make up your mind and have your doubts about someone's post without calling them a liar when you have no grounds to your assertion?

Hippobot · 09/11/2025 21:31

NikkiPotnick · 09/11/2025 20:57

You wouldn't know my friend the leading global clinician, they go to a different school.

Pathetic

RunSlowTalkFast · 09/11/2025 21:34

TheSlimmingPumpkin · 09/11/2025 21:24

And the pharmacy weight and height check I did which I uploaded

i am getting so forgetful

Again, this is not the case for all pharmacies, they are not allowed this strict.

PeopleWatching17 · 09/11/2025 21:35

MrsMiagi · 08/11/2025 23:50

There would still be medication in your friends system. Is she really hungry?

Probably not. Fat people don’t eat because they’re hungry; they eat because they enjoy food/emotionally need food/ are sad - the reasons are many. I’m almost never hungry, but I eat way too much. Currently dieting and down 4 stone. I won’t be trying injections.

usedtobeaylis · 09/11/2025 21:35

SilenceInside · 09/11/2025 21:29

@Hippobot the risks that your friend outlined to you are the same ones that we all are told about before making our own personal risk decisions. Not some additional knowledge of long term health damage that has yet to be published. Unless that’s what you’re claiming?

It is not stupid, naive, or poorly informed to make a different decision to you. The risks you listed are already known as rare side effects of this medication. Those are outlined before anyone is prescribed this medication. So to post about as yet unknown but severe long term health implications is simply scaremongering.

Half of them are also all noted effects of rapid weight loss, Mounjaro or not. Some are caused by the conditions people take Mounjaro for. It's just more un-evidenced scaremongering.

NikkiPotnick · 09/11/2025 21:37

Hippobot · 09/11/2025 21:31

Pathetic

Times like this I miss the laughter reaction button.

Honestly, they should add the way it makes some people seethe to the list of side effects to this drug.

Hippobot · 09/11/2025 21:39

SilenceInside · 09/11/2025 21:29

@Hippobot the risks that your friend outlined to you are the same ones that we all are told about before making our own personal risk decisions. Not some additional knowledge of long term health damage that has yet to be published. Unless that’s what you’re claiming?

It is not stupid, naive, or poorly informed to make a different decision to you. The risks you listed are already known as rare side effects of this medication. Those are outlined before anyone is prescribed this medication. So to post about as yet unknown but severe long term health implications is simply scaremongering.

I never said anyone was stupid, naive or poorly informed. It was a discussion I had in order to make my own, informed decision. If you were able to ask one of the world's top physicians and researchers, would you not do it, before starting something like this? So that they can go through the latest data but also the physiological mechanisms of the drugs and what that means holistically for a body longterm. And no, the known side effects are not what he discussed with me, those are concerning, yes, but it was the longterm damage to gut micrbiome, metabolism, mitochondrial function etc etc that we were more concerned about. Particularly the function of heart muscle. So yes, I am referring to long term projections that are not fully known yet but early evidence suggests there could be quite serious longterm issues.

I had listed the known side effects because someone had asked what kind of organ damage there can be. Losing part of your intestines to gastroparesis is worth knowing, for example.

SilenceInside · 09/11/2025 21:42

@Hippobot I imagine your friend is urgently updating the national authorities like the MHRA as well as all the relevant scientific bodies etc etc in order to whistle blow and get these medications pulled from the market.

PumpkinTwistyWindToots · 09/11/2025 21:43

Hippobot · 09/11/2025 21:39

I never said anyone was stupid, naive or poorly informed. It was a discussion I had in order to make my own, informed decision. If you were able to ask one of the world's top physicians and researchers, would you not do it, before starting something like this? So that they can go through the latest data but also the physiological mechanisms of the drugs and what that means holistically for a body longterm. And no, the known side effects are not what he discussed with me, those are concerning, yes, but it was the longterm damage to gut micrbiome, metabolism, mitochondrial function etc etc that we were more concerned about. Particularly the function of heart muscle. So yes, I am referring to long term projections that are not fully known yet but early evidence suggests there could be quite serious longterm issues.

I had listed the known side effects because someone had asked what kind of organ damage there can be. Losing part of your intestines to gastroparesis is worth knowing, for example.

Edited

Oh please. Gut microbiome? This is nonsense. Where did your 'friend' get hold of this secret research evidence? Or are you falling for the appeal to authority fallacy and assuming this person's no-more-informed-than-the-next-bloke's opinion is more valuable because they are a doctor?

Hippobot · 09/11/2025 21:47

SilenceInside · 09/11/2025 21:42

@Hippobot I imagine your friend is urgently updating the national authorities like the MHRA as well as all the relevant scientific bodies etc etc in order to whistle blow and get these medications pulled from the market.

That's not how medicine works.

Hippobot · 09/11/2025 21:48

PumpkinTwistyWindToots · 09/11/2025 21:43

Oh please. Gut microbiome? This is nonsense. Where did your 'friend' get hold of this secret research evidence? Or are you falling for the appeal to authority fallacy and assuming this person's no-more-informed-than-the-next-bloke's opinion is more valuable because they are a doctor?

I'll believe a medical researcher and top consultant over you.

SilenceInside · 09/11/2025 21:48

I think I was being somewhat sarcastic….

PumpkinTwistyWindToots · 09/11/2025 21:49

Hippobot · 09/11/2025 21:48

I'll believe a medical researcher and top consultant over you.

You didn't answer the question 😆

NikkiPotnick · 09/11/2025 21:49

PumpkinTwistyWindToots · 09/11/2025 21:43

Oh please. Gut microbiome? This is nonsense. Where did your 'friend' get hold of this secret research evidence? Or are you falling for the appeal to authority fallacy and assuming this person's no-more-informed-than-the-next-bloke's opinion is more valuable because they are a doctor?

There seems to be something about the gut microbiome issue that inspires Internet bullshitting. Long predates WLIs being common.

Frenchfrychic · 09/11/2025 21:50

Hippobot · 09/11/2025 20:54

I'm not talking about their approval though, am I? The post was talking about using them for life as a weight loss drug. They weren't approved as a lifelong weight loss drug actually. Short term for major obesity with other co-morbidities.

They are approved for lifetime usage to manage obesity.

look I’m sorry you’re fat and unable to take the drugs, for whatever reason, health, fear, cost etc, but you’re posting some right old shite.

Hippobot · 09/11/2025 21:50

SilenceInside · 09/11/2025 21:48

I think I was being somewhat sarcastic….

If you were hoping for humour it fell short. Top marks for bullying though.

Hippobot · 09/11/2025 21:50

Frenchfrychic · 09/11/2025 21:50

They are approved for lifetime usage to manage obesity.

look I’m sorry you’re fat and unable to take the drugs, for whatever reason, health, fear, cost etc, but you’re posting some right old shite.

Your opinion is based on what? Because the drug companies say so?

78e22387FFGH · 09/11/2025 21:51

It just is so annoying that it is said it takes on average 66 days of doing something for it to become a habit.

Well I have been off and on injections for 11 months - on for 5 months, off and on the last 6 - and eating less is STILL not a habit!!