On it for life then.........😐

[Ihavesomeballs]

I've lost 11kg on Mounjaro. I wasn't obese to start with but I'm tiny, 5ft 1 inch. I'm now just in the healthy weight BMI. I stopped my 5mg dose for 3 weeks as I had to wait till payday to order my next pen. In that time I wasn't eating any more than usual but I put on 2kg. So I guess I'm on it for life......which sucks as it's bloody expensive. Anyone else??

You're just eating more. That's it. Perhaps go back on. Make a detailed diary of intake and then go off and stick to similar. It's just your own willpower holding you back

Except we do. Because the drugs have been used for 10 years! That’s a pretty long time!

10 years with a small patient cohort with a specific health condition is not a longterm representative study.

What seems crazy? It’s great that you can successfully lose weight by eating less and being able to stick to that. Other people are different. Some people have tried to consistently diet many many times, and had the typical weight loss for a time and then a larger rebound leading to higher and higher weight in the long term. Some people therefore can use medications like these to help them lose the weight, to be able to stick to eating less for the amount of time necessary for meaningful weight loss. That’s all.

They haven't been used this way at all for 10 years and there have been virtually no studies actually.

I switched from Mounjaro to Wegovy a few months ago when the process went up but I ended up taking a 6 week break due to changing pharmacy and supply issues. So I went 'cold turkey' from 7.5mg (not ideal - I will slowly reduce when I come off again).

I gained 5lbs within 3 weeks but I use a body scanner at the gym and it was mostly water gain with a bit of muscle, it wasn't fat gain. Then over the next few weeks, it all came back off again before I restarted WLI.

So my advice would be not to panic at a gain when initially stopping injections. Just keep counting your calories and exercising and it should come back off.

Meh. I take a drug that isn’t licensed for my health condition (lithium) AND they don’t actually know how it works!

It’s just scaremongering. There are gallbladder risks with all weight loss. People just can’t stand fat people getting slim without excessive sacrifice.

My cardiologist is very happy for me to be on them.

@TheSlimmingPumpkin Try eating less and moving more is my favourite

@Hippobot given these medications have gone through the usual lengthy trials and are continuing to be researched I am happy that there are no horrific as yet unknown long term issues. I know that being BMI 50 for much longer was going to have a significant health impact on me in the short term. It already was. My overall risk of significant health issues has now reduced.

If your BMI is above 30 by all means you can take the jab. But not otherwise as you are just mis-using the medication and being lazy. Put in the effort. And I have children and no fancy equipment other than two sets of dumbbells 1kg and 3kg sets. I have a lot of sports injuries having played sports extensively in my younger days. But I still persevere. As I said my BMI is 25.5 so this jab is not meant for people like me. If your BMI has gone above 30 use it to get to a better level and then try to incorporate exercise. Saggy skin is not cool and only working out can help you there.

I like the ones where people suggest we add a little bit of exercise and see the weight dropping off. I'm a fitness instructor and I'd say relatively familiar with working out as a concept.

I’m under the dietetic department at my local hospital although I still have to privately pay for Mounjaro. The dietitian has told me that two thirds of people put the weight back on if/when they stop using weight loss medication. Yep, I’m on it for life too.

Here’s a study spanning non-diabetic people from 2016 to 2024

https://pubmed.ncbi.nlm.nih.gov/39171569/#:~:text=GLP%2D1%20RAs%20were%20also,and%20survival%20in%20this%20population.

You're saying this to a fat person who no longer has a gallbladder and highly does not recommend getting it removed. If I believed the hype without risk I'd take the injections myself. I won't. I'm glad the lithium is working for your condition and hope it continues to do so.

You are a fitness instructor with a BMI greater than 30?! Sorry but do people take you seriously?! I would find it very hard to take advice from someone who can’t follow their own advice. Do you actually advocate taking the jab instead of working out and eating healthy? Just amazing! 🤦🏽‍♀️

You clearly don't understand that what you're saying simply isn't true for some people. If it was that easy to eat less and exercise more than there wouldn't be so many overweight people. Some of us have insulin resistance, hormonal issues and inflammation. Obesity is a disease, it's not always a lifestyle choice.

Huh? You think th4 global health authorities, from the fda to the mhra and every other developed country just approved them with no studies?

👀

@HansHolbeinCan I ask how it’s fixing your PCOS please? Genuine question. I have PCOS and have been thinking about starting mounjaro. I’d love to know what effect it can have on PCOS. Thanks

Eventually the patent will expire and it will be cheaper. I plan on swapping to Ozempic once my current pen runs out, as I'm at goal so it's just for maintenance.

Wow, it's like a cult this. If you have an opinion other than thinking the longterm effects of taking this will be eternal health you are called a liar. I've never had so many people @ me on a post ever. If you don't believe me that is absolutely fine but it would be a pretty strange and pointless thing to lie about! I know him as I have a rare disease and was his patient for 15 years!

Oh you can have an opinion @Hippobot but if you’re happy to post it then you should expect people to consider it and analyse its worth. And of course some people will doubt grandiose claims, especially when they are making an appeal to authority against the prevailing science.

Nobody advocates taking WLI instead of working out and eating healthy, at least I've never seen that. This medication helps people who are unable to lose weight despite of working out and eating healthy.

I'm not talking about their approval though, am I? The post was talking about using them for life as a weight loss drug. They weren't approved as a lifelong weight loss drug actually. Short term for major obesity with other co-morbidities.

Mounjaro is approved for long term weight maintenance.

Well, those studies don't actually say they are "perfectly safe" if you go on PubMed and read the data. Likely safe is not the same as perfectly safe, is it?