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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

On it for life then.........😐

317 replies

Ihavesomeballs · 08/11/2025 15:39

I've lost 11kg on Mounjaro. I wasn't obese to start with but I'm tiny, 5ft 1 inch. I'm now just in the healthy weight BMI. I stopped my 5mg dose for 3 weeks as I had to wait till payday to order my next pen. In that time I wasn't eating any more than usual but I put on 2kg. So I guess I'm on it for life......which sucks as it's bloody expensive. Anyone else??

OP posts:
PumpkinTwistyWindToots · 09/11/2025 20:06

Janus · 09/11/2025 20:06

How is everyone getting this drug if you’re not even that much overweight?? I thought you had to be obese to get it? I’m about 4lbs overweight, ie it tips me from healthy bmi to overweight on the nhs bmi checker, feels like I could have a go then?! Everywhere I look you need a bmi of at least 35 so how are people getting it if they are just a stone over their desired weight??

Maybe these are people who have lost weight down from an obese weight?

Hippobot · 09/11/2025 20:07

usedtobeaylis · 09/11/2025 19:58

What is the effect of it on organs?

Heart muscle damage, pancreatitis, gastroparesis, kidney failure, bowel obstruction, gallstones, bile duct blockages, liver failure.

Hippobot · 09/11/2025 20:16

SilenceInside · 09/11/2025 20:00

@Hippobotyes, what is the effect on organs long term, and how do you know this information? Can you explain how this medication got through trials and approval in the UK if people’s organs “won’t be able to take it”?

Plenty of drugs get through trials but later are withdrawn as the longterm side effects become clear. If you think that pharmaceuticals are without risk you are very much mistaken. Has anyone actually read the patient info leaflet with these injections?

Hippobot · 09/11/2025 20:18

HansHolbein · 09/11/2025 20:06

Anyone for bingo?

How about you play side effects bingo instead?

HeidiLite · 09/11/2025 20:18

Happilyobtuse · 09/11/2025 20:02

Yeah, as long as you don’t eat endless junk the weight does come off. I hired a nutritionist and it has been great. I know what I should be eating and healthy snack options. I also had a full blood test done and found out I am iron deficient. Even though the weightloss is slow the inch loss from 30 mins of dumbells and pilates is already evident and it has only been 3 weeks. Definitely worth a try.

Edited

Yes I know people as well who only need to eat a little bit less and go for a walk and pounds will drop off. The trouble is that they assume everybody else is also like that, and if someone is struggling to lose weight, it's because they only sit on their arse stuffing their face with junk.
Which is obviously far from truth. The people I know who have successfully lost weight on WLI have all been fighting with weight most of their lives. Tried to lose weight many many times. Nobody wakes up one morning and goes on jabs for the fun of it. without first trying if a 30 minute walk might make a difference.

Hippobot · 09/11/2025 20:20

Happyjoe · 09/11/2025 20:01

Is it safe to take for life?

Highly unlikely.

TheLocust · 09/11/2025 20:21

Well who else do you think should be funding this?! Definitely not the tax payers

Obesity is a medical condition. Why should it not be funded in the same way as other medical conditions such as raised blood pressure, raised cholesterol or type 2 diabetes?

Hippobot · 09/11/2025 20:21

PumpkinTwistyWindToots · 09/11/2025 20:06

Yes

Mystic Meg has entered the chat.

SilenceInside · 09/11/2025 20:22

@Hippobot so, nothing other than hearsay from someone who should know better, and anecdote. Of course people have read the patient information leaflet. I think I know it inside out and backwards I’ve read it so much. You are listing known rare side effects. The risks of these very rare side effects need to be balanced against the many risks of being and remaining obese. The balance of these risks means that overall it is a benefit to obese people to take this medication. Their overall risk of serious health conditions will reduce, not increase.

The withdrawal of medications after approval is nothing to do with the existing known risks of side effects, which have already been considered before MHRA approval.

It’s just scaremongering. It also makes the mistake of thinking that remaining obese is a neutral position in terms of risk.

TheLocust · 09/11/2025 20:23

Because I have a close relationship with one of the leading clinicians globally

Sure you do.

Happilyobtuse · 09/11/2025 20:24

HeidiLite · 09/11/2025 20:18

Yes I know people as well who only need to eat a little bit less and go for a walk and pounds will drop off. The trouble is that they assume everybody else is also like that, and if someone is struggling to lose weight, it's because they only sit on their arse stuffing their face with junk.
Which is obviously far from truth. The people I know who have successfully lost weight on WLI have all been fighting with weight most of their lives. Tried to lose weight many many times. Nobody wakes up one morning and goes on jabs for the fun of it. without first trying if a 30 minute walk might make a difference.

well I have had two kids and lost the weight after but it came with hard work not easily as it does for some people. Working out is bloody hard. I wake up at 5.30 am to get some exercise in before working full time. I eat sensibly and food prep so that I avoid junk. I resist the urge to order takeaways. It is not easy for anyone once you cross 40 years to maintain their weight. So no just 30 mins isn’t going to make me skinny. But walking 12 K steps along with the daily workout and eating sensibly will make a difference. It will be much slower than any jabs but it will change body composition and increase muscle mass. Nothing good in life comes easy, you got to work for it!

SilenceInside · 09/11/2025 20:24

@Janus the prescribing criteria are a BMI of 30 or higher, or 27 or higher for certain ethnicities. Or 27 or higher if you have a weight related health conditions. They are the starting criteria, then of course you can then stay on the medication until you are in the healthy weight range, as that is the point of this medication.

Hippobot · 09/11/2025 20:25

SilenceInside · 09/11/2025 20:22

@Hippobot so, nothing other than hearsay from someone who should know better, and anecdote. Of course people have read the patient information leaflet. I think I know it inside out and backwards I’ve read it so much. You are listing known rare side effects. The risks of these very rare side effects need to be balanced against the many risks of being and remaining obese. The balance of these risks means that overall it is a benefit to obese people to take this medication. Their overall risk of serious health conditions will reduce, not increase.

The withdrawal of medications after approval is nothing to do with the existing known risks of side effects, which have already been considered before MHRA approval.

It’s just scaremongering. It also makes the mistake of thinking that remaining obese is a neutral position in terms of risk.

Calling the medical knowledge of one of the world's leading clinicians and researchers "hearsay" is laughable. I'll listen to him thanks. You believe what you like. Time will tell.

Ihavesomeballs · 09/11/2025 20:25

Happilyobtuse · 09/11/2025 19:53

Well who else do you think should be funding this?! Definitely not the tax payers!

I am insulin resistant and slightly above BMI at 25.5 but I am taking the healthy route and working out daily. 30 mins of pilates, dumbells etc. and 12K steps a day. I am not obsessed about the scale. The weight will come off, I just have to eat sensibly. Also as one grows older it is important to build muscle otherwise your skin will sag. Better to work out that keep using injections.

I do ......🤦

OP posts:
HansHolbein · 09/11/2025 20:25

Hippobot · 09/11/2025 20:18

How about you play side effects bingo instead?

Not had any so far, in nearly 13 months.

The positive effects have been truly life changing, though.

Happy to take the small risk of side effects, verses the very real risks of a BMI of 47.2, which I used to have.

Very happy with my decision to be on them for life, not concerned.

I’m not concerned about what other people who have made an informed choice about their health do. I am so happy for all of us. So many lives changed. More related medicines are coming out in the coming years, prices will come down. It’s just great!

RunSlowTalkFast · 09/11/2025 20:26

HeidiLite · 09/11/2025 20:18

Yes I know people as well who only need to eat a little bit less and go for a walk and pounds will drop off. The trouble is that they assume everybody else is also like that, and if someone is struggling to lose weight, it's because they only sit on their arse stuffing their face with junk.
Which is obviously far from truth. The people I know who have successfully lost weight on WLI have all been fighting with weight most of their lives. Tried to lose weight many many times. Nobody wakes up one morning and goes on jabs for the fun of it. without first trying if a 30 minute walk might make a difference.

I've used weight loss injections but I can admit that I eat too much and am not denying the laws of thermodynamics.

MrsJeanLuc · 09/11/2025 20:26

Ihavesomeballs · 09/11/2025 14:48

Once I get to goal I'm going to reduce my dose to 2.5mg and try stretching out my injections to 10 days and see how I get on. That's still going to be £130 every 6 weeks. It's so unfair that we have to fund this medication ourselves.

I wanted to do this, but the pharmacist was very insistent that you can't keep the pens more than 28 days.

I think you answered your own question earlier - in order to maintain without the jabs you may have to go back to cutting carbs out of your diet.

Kittyloulou · 09/11/2025 20:27

this all just seems crazy to me. I’ve lost 8lb in 3 weeks by just eating less. Cost me less than usual.

mathanxiety · 09/11/2025 20:28

Happilyobtuse · 09/11/2025 19:53

Well who else do you think should be funding this?! Definitely not the tax payers!

I am insulin resistant and slightly above BMI at 25.5 but I am taking the healthy route and working out daily. 30 mins of pilates, dumbells etc. and 12K steps a day. I am not obsessed about the scale. The weight will come off, I just have to eat sensibly. Also as one grows older it is important to build muscle otherwise your skin will sag. Better to work out that keep using injections.

Penny wise and pound foolish there.
I believe very strongly in taxpayer funding of MJ and wegovy and whatever other meds in the same category that will be developed over time. The difference they will make in the overall cost to the taxpayer of providing the NHS will be huge.

It's nice for you that you have the time and money and means of access to the equipment you use. It's also nice that you don't have a bad back or a gimpy leg or a frozen shoulder or crushing menstrual symptoms or exercise-induced asthma or problems getting someone to look after your children while you maintain your fitness. There are lots of people out there who don't have what you have going for you in their lives, and your exhortation of fitness s the way to go wouldn't really be relevant to them.

SilenceInside · 09/11/2025 20:28

@Hippobot I base my decisions on relative risk, not beliefs, and I am more than happy with my decision. Best thing for my health I’ve ever done, BMI down from 50 to 26, and many many other health benefits as a result. No serious side effects and no side effects at all for 12 months now.

Hippobot · 09/11/2025 20:31

HansHolbein · 09/11/2025 20:25

Not had any so far, in nearly 13 months.

The positive effects have been truly life changing, though.

Happy to take the small risk of side effects, verses the very real risks of a BMI of 47.2, which I used to have.

Very happy with my decision to be on them for life, not concerned.

I’m not concerned about what other people who have made an informed choice about their health do. I am so happy for all of us. So many lives changed. More related medicines are coming out in the coming years, prices will come down. It’s just great!

Good. I'm glad that's the experience you've had. However, posting things that mock those who have had their lives ruined by the injections just because that wasn't your experience is rather childish. These are new drugs and people's bodies react wildly differently to them. For every person that has had no side effects there is someone who has had. Being cautious about what this will do to the body over a lifetime is not to be mocked with some stupid bingo post.

Ihavesomeballs · 09/11/2025 20:31

Janus · 09/11/2025 20:06

How is everyone getting this drug if you’re not even that much overweight?? I thought you had to be obese to get it? I’m about 4lbs overweight, ie it tips me from healthy bmi to overweight on the nhs bmi checker, feels like I could have a go then?! Everywhere I look you need a bmi of at least 35 so how are people getting it if they are just a stone over their desired weight??

My BMI was 28 but I've also got high blood pressure. I think you have to have a BMI of 27 with a medical condition to qualify.

OP posts:
Hippobot · 09/11/2025 20:32

SilenceInside · 09/11/2025 20:28

@Hippobot I base my decisions on relative risk, not beliefs, and I am more than happy with my decision. Best thing for my health I’ve ever done, BMI down from 50 to 26, and many many other health benefits as a result. No serious side effects and no side effects at all for 12 months now.

You don't actually know the longterm relative risk yet though as that evidence does not exist yet.

FoxRedPuppy · 09/11/2025 20:32

Hippobot · 09/11/2025 20:16

Plenty of drugs get through trials but later are withdrawn as the longterm side effects become clear. If you think that pharmaceuticals are without risk you are very much mistaken. Has anyone actually read the patient info leaflet with these injections?

These drugs have been used medically for over 10 years with diabetes patients. It’s only recently that they are just for weight loss too. So they have 10 years worth of studies and case studies. And from that they are perfectly safe.

TheSlimmingPumpkin · 09/11/2025 20:33

I like playing bingo and love our bingo card. I have my pen 🖊️ at the ready