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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

November 2025 Mournjaro starters

1000 replies

Nearlyamumoftwo · 01/11/2025 15:05

I've just collected my first supply and wondered if anyone wanted to join in with the journey! I'm on 2.5 and I'm 14st1, goal weight is 12 stone as that is my pre baby weight and we'll see how I feel once I've reached it!

any tips on when to take it each week? I'm going to avoid alcohol and even though snacking is my weakness I think purchasing a supply is going to make me stop in a weird way. Any tips gratefully received and if anyone wants to join the journey for support and no judgment here's the place!

OP posts:
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SexyFrenchDepression · 02/12/2025 11:31

Middle of my week weigh in today, 2 milestones, 15lb off, and under the next stone. Feels nice to see 10 something on the scales even if it is practically 11 stone. Such a long time since I have seen those numbers and I am so grateful I decided to go with the WLIs.

Will go up to 3.75mg on Thursday, will see how the 1st couple of weeks go and maybe drop down, I am doing fine on 2.5mg but didnt really know you cld stay on that low so automatically ordered 5mg, not sure it is ok to keep the open pen going 9 weeks! I will try and get all the medication from the 5mg pen which means going over the 30 days but a lot of people seem to do this. I will check it all properly but the main issue seems to be that it may just not work as well or that you have to be careful re hygiene piercing the seal more times, although same pen is used for insulin and it is then pierced 3 times a day so way more than 6 times in total.

diggitydoo · 02/12/2025 11:36

Thanks , I've just ordered my second pen through bolt. I will take my last dose of 2.5mg on thursday and have ordered 5mg through bolt for next week. Can't decide whether to try for the golden dose or not, but I'll have both options so can decide next week.

Feeling really hungry today! Feel like I could eat and eat .. already had a breakfast and a snack and still hungry! :-(

SexyFrenchDepression · 02/12/2025 12:12

Woodenwonder · 02/12/2025 10:56

I did my second jab on Sunday. I'm not weighing myself for my own mental welfare as I'll get obsessed I know I will and be stressing it's not happening fast enough or whatever. I feel I've lost a little weight off my boobs but other than that I don't feel massively different yet and no major side effects. Definitely more hunger pains this week than last week but I'm not eating a great deal so I need to put some systems for healthy and regular eating in place.

I generally weigh 2 or 3 times a week, it was recommended by my PT as they work on average weight loss due to the many fluctuations. I know some people weigh every day so they learn about what food/times of week or month effects them more but I started getting really stressed about that if I went up a tiny bit so I do Tues and Sat only. I find i can cope with that ok mentally.

SexyFrenchDepression · 02/12/2025 12:14

diggitydoo · 02/12/2025 11:36

Thanks , I've just ordered my second pen through bolt. I will take my last dose of 2.5mg on thursday and have ordered 5mg through bolt for next week. Can't decide whether to try for the golden dose or not, but I'll have both options so can decide next week.

Feeling really hungry today! Feel like I could eat and eat .. already had a breakfast and a snack and still hungry! :-(

You should get close to 3.75mg out of the golden dose so could be a decent step up. I only got 2.91mg as I messed up priming one of the times and wasted loads!

Flossyknicks · 02/12/2025 19:06

I’ve been keeping my pen in the fridge but I’ve just read the instructions again and you don’t have to do you?! Is everyone just keeping it at room temperature? I’m going on holiday and didn’t think I could travel with it

putthehamsterbackinitscage · 02/12/2025 19:31

It is fine out of the fridge once you have used it.

fir travel, it depends on where you are going and the likely temperature- if it might be as high as 30, then you’ll need a cool bag for travel and a fridge.

Springbaby2023 · 02/12/2025 20:48

Oh I’ve been keeping it in the fridge too. Why is that then?

SexyFrenchDepression · 02/12/2025 20:58

It can be kept out of the fridge for 30 days in total, I have a couple in the fridge as I havent started using them yet but just jabbed as soon as I received ny 1st one so that was out of the fridge the whole time. I will keep these in fridge the whole time as I will probably use them longer than 30 days.

tobee · 02/12/2025 21:11

Weird.

I felt like my desire to eat was stronger tonight and I was tempted to eat more dinner because it was yummy but I feel stuffed after eating a prawn salad with stuffed tomatoes. I made 2 large tomatoes stuffed with garlic, shallots, Parmesan and breadcrumbs. The stuffed tomatoes have made me stuffed. The breadcrumbs were about 1 tablespoon.

First bread I've eaten since starting.

Sorry that's a bit long and detailed. Bit navel gazing 😆But it's still strange and new.

tobee · 02/12/2025 21:13

Yes once I did jab 1 I kept it out of the fridge. But kept doubting myself and checking I was doing the right thing.

Springbaby2023 · 02/12/2025 21:23

That’s good to know, I’ll start keeping it out!

How’s everyone doing this week?

I’ve had zero side effects which is great, feel like it’s a sign my body is getting used to it now which makes me feel more positive about stepping it up on Sunday. Quite excited to see what impact a higher dose has as I’m definitely still not getting a high level of suppression, especially as the jab wears off.

I did two workouts today so pretty chuffed with myself, would never have done two in a day pre MJ but it really is helping to motivate me. And my NSV for the week, some jeans which I’d stopped wearing as they were getting just too tight to be comfortable now fit perfectly again!

SexyFrenchDepression · 02/12/2025 21:43

I have been shocking at going to the gym but I have been doing so much house sorting that I have been probably lifting just as much and running around all day, I think I have just run out of energy by the time I should go to the gym. Need to go tomorrow as running out of days to fit 3 sessions in this week!

Feeling good this week, was a month yesterday I have been on the jabs so done 5 jabs so probably just getting used to it. Did golden dose and had slightly more than 2.5mg left, not much though and felt the most normal this week I have since starting.

As I am having zero side effects I am feeling better about going up to 3.75mg now, will give that a couple of weeks then may go up to 5 if need be.

RoundandSad · 02/12/2025 22:08

Confused about the fridge thing too now

Well, mine is in transit and they tried to deliver it today, but there was no one home

That's another reason I find Voy strange, I would really like to be home when it's delivered and if they give more warning, I'll stick to a date then it's easier to sort out

So the post office are gonna try and re-deliver tomorrow and DH should be here. I don't know how long they could keep that at the sorting office if no one's here?

I know it comes with the cool packs, but - oh I suppose it's alright if I'm allowed to keep it outside of the fridge and a rural mail warehouse is probably very cold

It really makes me wonder what we're being told, my current pen has a very long expiry date on it, but it's 30 days after you've pierced it? That's going to be complicated as I have a 5 mg pen coming and trying with 3.7 first but if that goes okay then I'll go up to 5. If it doesn't go okay then the pen's gonna be open for a lot longer.

RoundandSad · 02/12/2025 22:08

Is it like eyedrops?
They tell you to throw them away after a month, but there's nothing wrong with the actual solution. It's the potential for contamination and they say that some people touch their eye with them. At least that's what the pharmacist told us. But there's actually not really a reason you can't keep them for much longer than that.

SexyFrenchDepression · 02/12/2025 22:11

@RoundandSad technically its only supposed to used for 30 days once opened whether its in the fridge or not, expiry date is for unused pens. I will be doing 3.75mg from this week and storing in the fridge instead of out and hope it'll be fine to use a bit over 30 days. Lots of people do this.

RoundandSad · 02/12/2025 22:13

@SexyFrenchDepression i'm so nervous about going up to 5 mg

One other thing that I realised is that I'm due to jab on Boxing Day and we are very quiet between Christmas and New Year so it might be worth saving the 5 mg till then

So that would be three jabs of 3.75mg - but only if the three times go okay

This bit should be easier than starting brand-new, shouldn't it? We didn't have anything in our system, but now we do. The medication already is in our system surely starting from scratch should be the worst bit

SexyFrenchDepression · 02/12/2025 22:28

RoundandSad · 02/12/2025 22:08

Is it like eyedrops?
They tell you to throw them away after a month, but there's nothing wrong with the actual solution. It's the potential for contamination and they say that some people touch their eye with them. At least that's what the pharmacist told us. But there's actually not really a reason you can't keep them for much longer than that.

Thats my understanding, apparently its how many times the seal is broken but the pens are used for insulin which are used 3 times a day so its fine then, I guess just using good hygiene and storing correctly means itll be OK. I use eyedrops for months as its only me using them and I've survived 🤣

SexyFrenchDepression · 02/12/2025 22:31

@RoundandSad mine is due xmas day so I will just take late afternoon instead of morning. That will be my 4th jab of new dose so I will go up to 5 if I havr felt ok also. I am sure it won't be as bad as the initial doses.

RoundandSad · 02/12/2025 22:57

@SexyFrenchDepression all we want for Christmas is our weight loss jabs 😂

No seriously, I thought it would be good time to try because it's just quiet family time between Christmas and New Year. Big day on Christmas Eve, but that's Wednesday so that's the day at least effect. Not planning to overeat though extended family will notice what I eat. Weird. That's lunch and then we've got an evening party with DC but that isn't focused on food

I use eyedrops till they run out. My parents were quite cross when I told them what the pharmacist told me. They use some quite expensive eyedrops, they need them for some reason and they were diligently throwing them out every month. It must've cost a fortune over the years.

I didn't know that about insulin that makes me feel better and safer.

SexyFrenchDepression · 02/12/2025 23:08

@RoundandSad its true 😂 and not to put on over half a stone which is what I normally do!!

I definitely want to have full effects from boxing day onwards as I usually eat my body weight in cheese, bread and chocolate so I will feel so much better not doing that!!

TaffyTabby · 03/12/2025 08:44

Ah thanks for mentioning timing of jabs over Christmas because that hadn’t even occurred to me. Mine were due on Christmas Eve and NYE which would have been awful really. I think my plan is to go up to 3.75mg but inject every 8 days so I can move my jabs past those days.

I have been stuck at the same weight for over a week now but trying to look at the positives:

  • not gaining! I had been gaining for months
  • I’m eating much less snacks, sugar, processed foods and more nutritious foods
  • I’m slowly getting used to the medication so in the new year hopefully I’ll be ready to really focus on losing

And if I wasn’t on MJ, I would definitely gain loads over Xmas. I want to be able to enjoy Christmas dinner but I don’t want to go bonkers!

SexyFrenchDepression · 03/12/2025 08:57

@TaffyTabby yes I would be the same, already the Xmas meals and parties have started so I would be properly over indulging and starting to put on weight!! Often for me the worst week is the 1st week in Jan where there are still leftovers in the house and because I want them out of sight I binge eat them all resulting in even more weight gain!!

TaffyTabby · 03/12/2025 10:01

@SexyFrenchDepression snap! I have this ridiculous psychological thing about needing to finish any tempting food to get rid of the temptation. Makes no sense. I have a lifetime of dysfunctional eating thoughts and behaviours that I need to try and undo. My fave thing about these meds is definitely that I think less about food.

SexyFrenchDepression · 03/12/2025 10:08

@TaffyTabby same, I have never had a normal relationship with food, my mum was obsessed with diets and being thin, she hates fat people and comments all the time. I dont feel the same as her in any way however it has totally messed me up when it comes to normal eating, I either starve myself or binge! As a result I have always rewarded my DCs with food and both are overweight as older teens. I feel awful about it and need to sort it out for them!!

bakingmad123 · 03/12/2025 12:48

Hi all, I was wondering what we are all doing for exercise at the moment - e.g what types, how long a session and how often? I do like exercise but am struggling with tiredness and feeling weak - I also broke my leg in the summer so am only just getting back to exercising after a long time of being immobile - and am obese which makes it hard!! I’m aiming for walking on treadmill for half hour twice a week, strength training for 40 mins twice a week and swimming twice a week. Finding it hard to actually achieve though as I just feel knackered!! (I’m just over a month in and on 5mg currently)

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