What opinion about WLI would you not normally admit to?

[LittleMissContrari]

Do you have an unpopular or unpalatable opinion?

Mine is that if you can't do the maths, you probably shouldn't be messing about with the dosage.

I agree, I've been losing a pound and ahalf a week on average and think its fantastic and very relaxing not have to worry about it

Mine is horrendously unfair as it's probably typos. But every time someone calls it 'Mountjaro' or (shudder) 'Munjaro', I want to peel off my own skin in irritation.

I've been in a Facebook group today where people have been celebrating losing a stone per month. Not surprisingly I've left the FB group. Providers shouldn't allow such messages anymore than they'd allow a criticism about their customer service..

Thanks for pointing to the maintenance study. Quite a sober read.

jamanetwork.com/journals/jama/fullarticle/2812936

The adverse events in table 3 is very interesting. Does coming off it cause more issues for some people or is it just coincidental?

While I agree we should do something about the issues you mention, they're not the underlying problem when it comes to obesity.

People can and do get obese without that kind of food. The actual problem is that we evolved to eat lots of food when we could get it, to sustain us during periods when there wasn't much. We no longer live in that environment, and we've kept the evolutionary desire to eat without the corresponding periods of starvation that stopped us becoming obese.

We can get rid of the lower hanging fruit, but what we'd still be left with is whole societies of people who can and will access more calories than they're going to burn off, over a lifetime. I'm in favour of your idea, but we also ought to be realistic about what it would do.

That obesity is a long term condition and people need to find ways to manage it that works best for them and their individual circumstances, not what suits other people online.

That people who lose weight successfully and sustainably, do so by taking a long term view and adjusting their diet and exercise to fit with their lifestyle. People who save calories from their allowance for occasional foods they enjoy, do better long term than purists who are unable to maintain their unrealistic regime.

If injecting lower doses more frequently reduces side effects, and works for you, why wouldn’t you?

If you are on holiday, and have less control over what you eat because someone else is preparing the food, why not take a short break from injections to avoid unpleasant side effects?

If a maintenance dose helps people to stay healthy, why criticise them? What business is it of yours?

That people who have been supported on these boards should probably pause before slagging off the people who have been kind to them and that people who are overweight and obese should think before criticising the diets of others.

I think table 3 shows that whatever treatment you might take, shit happens.

Take blood pressure medication for a long time and no one blinks an eye lid. Say the same about Mounjaro and everyone seemingly has an opinion.

Why isn't obesity seen as a condition that requires long term intervention?

If you are going encourage practices with unknown risks and with no credible evidence of their safety just admit you are being reckless and don’t actually have a clue.

Absolutely all of this. This thread is very disheartening.

If a maintenance dose helps people to stay healthy, why criticise them?

The evidence shows that maintenance doses help people avoid weight regain.

That’s not the same as “stay healthy” - that all depends on the long term effects of taking it over a long period, which we don’t fully know yet.

Keeping the weight off is staying healthy - I have recently had all my bloods done for the first time since starting MJ - and everything is now in the healthy range. I am 58 with a family history of atherosclerosis, dementia, diabetes, CVD/stroke and cancer. These are all much reduced risk with weight loss and maintenance - alongside muscular skeletal issues and osteoarthritis.

We have had years of use in diabetes where the safetly profile has been established.

Keeping the weight off is staying healthy

I wholeheartedly agree. I’m 67 and have blood tests done routinely as part of my yearly well women check ups. Because I knew (at my age) Mounjaro really was my last chance to set myself up to hopefully add years to my life and lose weight once and for all, I deliberately had bloods done the day I started Mounjaro on the 15/8/24 as part of my battle plan.

I knew I was prediabetic for the 2nd time, that I was on medication for 1stage HBP, and that my cholesterol levels had drastically changed over a short period of time from ‘still ok’ to not good at all and ‘we have to think of medication for this’

Six months into my Mounjaro journey when I had the tests repeated my blood sugar was normal, but I knew that because I’d been checking it every day. My cholestrel levels were in the excellent range of normal, and just last week I was taken off my blood pressure medication - I no longer have HBP.

Health wise I haven’t felt so well for years. I’m as fit as a fiddle and once the weight started coming off I could see the muscles I’d built over the years I’d been a crossfitter and having personal training. My advice to anyone is - if you’re not already an excerciser then the day you start Mounjaro is the day you start to excercise. It’s also the day you start putting in new habits to see you through everyday of the rest of your life. Losing weight should never be a persons only focus on this journey, you have to take a whole person approach to it and that includes working on your health, your heart and your head as well.

Once a person has seen those new blood test results and they feel like an all round different woman there’s no better incentive to staying as healthy as you can be, everyday, for the rest of your life.

One year on I’ve lost just under 4 stone on 1500 calories per day. I’m 3 pounds away from my target which I was hoping to do by my anniversary on 15th of August but I doubt that will happen as I’m having a bit of a stall. But that’s ok. My body knows what it has to be doing to keep me well and I know for sure things will start moving again when it feels the time is right. My target weight has never been to reach even the top of my BMI. I don’t believe in it and I’ve decided on a stone above it. I’m very happy with that, I had a dexa scan recently and I know exactly what I’m made up of. And if when I’m titrating off Mounjaro I lose a couple of more pounds then that’s great, but once I reach my goal of 85kgs that’s it.

Sorry, just to add. I’m on 10mg of Mounjaro. I did try 12.5 for 2/3 weeks but it wasn’t for me so I went back to 10.

MN unpopular opinion threads often feature lots of opinions that are unpopular because they're stupid. It seems WLI is not immune!

Diabetics have been taking them for 20 years. Are you saying you expect side effects to be different in those who aren't diabetic? And what's your rationale? The long term side effects could be different - we don't know yet. We do know the long term risks of being overweight though. Right now I'm taking my chances on mounjaro.

Non wli users jump in on various threads. They normally stand out a mile for sharing their “expert“ opinions. Frankly I think they need a new hobby that isn't based on bigging themselves up or putting users down..

Non wli users jump in on various threads. They normally stand out a mile for sharing their “expert“ opinions. Frankly I think they need a new hobby that isn't based on bigging themselves up or putting users down..

They also need people who are on WLI to counter their opinions and as we say in Scotland - put their gas at a peep.

Yep. Its a position that can only be arrived at by someone who doesn't understand that the result of no maintenance prescribing is weight gain with all the corresponding risks.

People calling it monjaro

I work closely with the community eating disorders team through my work. Patient numbers are skyrocketing. Both because anorexics are easily able to get hold of these drugs, and because so many people (predominantly women) who have started these drugs legitimately have ended up underweight with eating disorders as a result. They are very worried about what this is going to look like in a few years time.
Unpopular because people who do qualify don't want it to be harder to get (understandably) but I think it needs to have far more checks in place, in person pharmacy distribution only, through GP surgeries (not necessarily GPs themselves but other practitioners) or specialist weight loss clinics run by medical professionals and tougher penalties for beauticians and hair salons selling it - it's drug dealing and should be treated that way. This is a prescription medication and it needs to be available to those who qualify with ongoing decent quality follow up to ensure they aren't descending into problems, and not available to those who don't.

I’m almost 50 so fully prepared to take the risk of ‘staying healthy’ by using MJ at a maintenance level.

The alternative risks of being morbidly obese for me are almost certainly much worse.

The difficulty with further involvement of GPs is that the service is already so stretched, and that doesn't include only GPs themselves. Even if WLI users were to pay extra for this, it doesn't mean the resources are there.

I’ve just been away and didn’t take the pen… but it was because it would have been impossible to keep pen at temperature. No fridge and 35-40 degrees. So one week off. Stayed eating sensibly and drank very little alcohol (really didn’t fancy it) and drank buckets of water. Came back home with a slight drop in weight.

Agree many of the other comments though.