Has anyone had a good result with mounjaro?

[Marinamay44]

I thought it would be so different to what I have experienced. I thought that I would be less hungry and that I would feel fuller for longer.

Three weeks in on 2.5, I have been just as hungry as I have always been. I have felt no appetite suppresant effect at all. The only thing it's done for me are bad things: it has given me nausea and diarrohea.

I didn't think it would be like this. It is such an expensive drug too.

It is definitely making a huge amount money for Novo and Eli Lilly.

Im glad if the drug is working for some people too.

I was told the initial dose is to see if you get side effects because some side effects are servere.

I am just annoyed because I feel like I got caught up in the hype of it being a wonder drug, and it has done nothing for me whatsoever, except for getting me to shell out a lot of money.

I have felt more appetite suppressant effects from drinking herbal tea.

@Marinamay44its done nothing for you YET. And this dose level isn’t supposed to produce weight loss, on average, for the majority. You’d be fortunate if it did. You are unlucky with your side effects, certainly. You’ll only know if it doesn’t work for you at all, if you work through the doses and lose no significant weight.

If it’s any consolation OP I am losing at exactly the same rate as others on here after coming off it - the slower end admittedly ! Mainly sticking to 1300 cals a day, high protein, low carb, full fat Greek yoghurt and cottage cheese, eggs, berry’s, fish/chicken/prawns and salad and boatloads of water. No snacks at all , no cake, bread, biscuits, ice cream etc , far less alcohol - if it doesn’t suit you and I would give it at least your first full pen -then go back to the traditional way -I also use herbal appetite suppressants ( Berberin) before evening meal and I think that helps they have a low GLP1 dose to them and have had no side effects at all on them

I think that I will try it for two more months.

If I feel nothing whatsoever at that stage, i will stop.

I didn't get suppression until I was on10mg, month 4. Nearly 7 stone down now.

You've taken three doses of it. Three.

I'm 7 months in, 5 stone down. It is a wonder drug. I have a total of ten stone to lose. I'm expecting to be on this at least another year to reach the middle of my healthy BMI. I'm anticipating being on it for many years to maintain the weightloss - potentially my lifetime.

It's a marathon, not a sprint. How much weight do you need to lose? How long did it take to put it all on?

Why do you think you'll see a miracle in 3 doses? No medication of any type cures you in such a small amount, not even painkillers as they don't cure the pain, just hide it.

How long did it take you to feel appetite suppressant effects?

Thanks for sharing that.

10 months in and I’ve lost 5st. Down from 14st to 8st12.

I track my calories, prioritise fibre and protein and real food and it’s worked.

It’s not overnight and it’s not without thought and work. Just have to keep going and keep making the choices that support a lifestyle change.

there have been times I’ve stalled or felt like I’m getting no where, but staying consistent has meant I moved through it.

But if you read up on it beforehand, surely you read the very clear guidance that tells you that 2.5mg is a starter dose and that many users do not get appetite suppression and weight loss on this dose?

That doesn’t mean the starter dose is a waste of time and money - it's designed to get your body used to the medication so that your side effects when you move up are less severe.

The starter dose worked for me and for many others, but there were patients in the clinical trials and in real life who didn't/don't see significant weight loss until they move up to 12.5 or 15mg.

However, those patients could not have started on such a high dose because it would most likely cause severe illness - worse than the diarrhoea that the starter dose has given you.

You should talk to your prescriber and get medical advice. This may well not be a suitable drug for you. But the fact that 2.5mg hasn't been effective for you is not unsurprising - that's the case for many users.

I felt immediate suppression on 2.5mg, only SE has been constipation.
I’ve had 4x 2.5mg doses and 3 x 3.75mg and have lost 2 stone.

Where are you injecting OP, I’ve heard that can make a difference. I always use my stomach.

I inject in my thigh. That is interesting, I will try my stomach next time.

I'm a super responder - the same as my migraine injections. I respond instantly. However I am in the minority. I didn't anticipate it.

You also have to put in all the work - the drug is a tool, but you have to control your diet and exercise. It just enables you to do that.

Expecting the drug to miraculously remove all hunger is unrealistic. It increases satiety which means you still eat, you may just find you want to eat a bit less. For some that results in near starvation levels of food intake, for others like me I can still overeat if I choose to buy it enables me to choose to eat less for the first time in my life.

At the time of purchase I was told not many people actually start feeling the effects until 5mg. I appreciated the starter dose, it allowed me to get used to the drug.
sounds like you haven’t done a lot of research op

I didn' expect it to miraculously remove all hunger. I expected it to have SOME effect. It is marketed as an appetite suppressant. I have felt nothing yet.

Why? You said you'd done your research. 2.5 is not considered to be a therapeutic dose.

I hope that makes a difference for you. 🤞

Again…..
2.5mg is not for glycemic control.

And yet there are posters on here who said that they felt appetite suppressant effects in their first month?

Can you tell me how they are meant to work out who will get results on what dose without them actually trying it?

Yes, I hope it does.

Yes but we are in the minority. Most people don't. People respond differently to the drug - this is another reason why it's important to start on a low dose so that you can find out how sensitive you are to it. Some of us don't ever have to move up the doses. Others will need to go all the way to 15mg for it to work.

My DP had quite extreme suppression at 2.5, and if anything too much at 5. So that’s not true for everyone.