Has anyone had a good result with mounjaro?

[Marinamay44]

I thought it would be so different to what I have experienced. I thought that I would be less hungry and that I would feel fuller for longer.

Three weeks in on 2.5, I have been just as hungry as I have always been. I have felt no appetite suppresant effect at all. The only thing it's done for me are bad things: it has given me nausea and diarrohea.

I didn't think it would be like this. It is such an expensive drug too.

Yes, they are businesses who want to make money. Lots of money. However, their desire to make money relies on them formulating safe, effective drugs. No-one is going to take the drugs if they don't work, or they kill everyone who takes them.

And yes, GPs are courted by pharma companies to get them to prescribe their drugs. This has been the case for literally decades.

I can't work out if you're genuinely ill-informed about Mounjaro, or you're just shit-stirring.

LOL Big Fat really! And Big Vegetable, who are the really scary ones.

It’s been approved for use following long and detailed clinical studies, showing a slow titration through dosage amounts. No more than a 2.5mg increase every 4 weeks to avoid the side effects.

It’s not a miracle drug and you shouldn’t just jump every 4 weeks. It’s a very long term medication.

It says clearly on the Lilly website that 2.5mg isn’t for glycemic control. It will be for initial tolerance of any side effects.

Website here for further reading - mounjaro.lilly.com/hcp/getting-patients-started

They start everyone on a low dose because of the prevalence of gastric side effects. Your other thread describes how you had diarrhoea at the airport - imagine how much worse that could have been if you'd gone straight to a higher dose!

Not to mention Big Gym, if op decides to exercise. Awful.

Oh, is this airport diarrhoea lady? And she thinks 2.5 is some nonsense dose to just make money 😆

Pharma companies have to invest BILLIONS to find one medication that works. To do that they have to first identify the hundreds of drugs or treatments that don’t work through expensive development and sales.

Yes they are BIG PHARMA but unfortunately they are needed to keep cycling through the R&D cycles to find the next thing to invest in, which comes at huge costs and risks.

There is also thread after thread about side -effects. Just because some has posted their experience already, doesn't mean that no one else is going to talk about the same thing in their experience.

There is no rule on this forum that says:

Only one person can write about having a negative experience on mounjaro. No one else can ever write anything

That would be ridiculous.

OP, if your posts today are some kind of psyop against Mounjaro, you're going to have to try harder 😄

Yes I am airport diarrohea lady. Thanks for the lovely name, and laughing emoji. It is nice to laugh at other people's suffering isn't it?

Both of my threads say the same point.

The low dose has done nothing good for me at all, and has given me extreme side effects.

So how was a low dose supposed to prevent me from getting side effects?

A low dose hasn't prevented me from getting side effects at all.

I have never taken a drug before that has given me no benefit whatsoever, and has just given me side effects. Mounjaro has.

Ignoring for a moment the very good medical reasons for allowing your body to get used to the drug as pp have pointed out, higher doses cost more so your big bad pharma logic doesn't really work.

Starting people on 2.5 means many people may stay at that level - or, like me, at 5 - for a long time or even for their entire time on MJ and never pay for the more expensive doses.

And, yes, weird thread title given the vast numbers of threads which answer the question.

There is no rule on this forum that says:
Only one person can write about having a negative experience on mounjaro. No one else can ever write anything

That’s correct. Nothing wrong with discussing your side effects. I was referring to you asking if anyone has had a positive experience, and your suggestion that it’s all a big money making scam.

My journey sounds exactly like yours. I'm 6 months in and remain on 5mg.

Actually, Big Pilates is draining my bank account. Big Running is cheap really. Except for Big Running Shoe, now those bastards have it sewn up.

It doesn't sound like you've done much reading or research before you started on the injections OP.

And in answer to your question, OP, I found 2.5mg immediately effective with strong suppression. I stayed on 2.5mg for a few months - going up to 5mg gave me D&V so I went back down. I haven't gone higher than 5mg and have spent most of my time on 2.5mg.

I've lost five stone in a year. My starter thread is full of success stories. Mounjaro is absolutely not for everyone. It causes side effects and it's expensive. It's making enormous profits for Novo Nordisk (or Eli Lilly, whichever one it is!). It's also changing a lot of lives and feels like nothing short of a miracle for many obese people who finally have found something that works.

A low dose hasn't prevented me from getting side effects at all.

Your side effects would have been worse at a higher dose. Surely you understand this?

It’s not to prevent you getting side effects. Its showed up you can’t tolerate it, before you go on a higher dose that does have glycemic control.

If you can’t take the side effects, you should stop it and not be prescribed any more.

I’m allergic to penicillin. I wouldn’t dare take it and then moan when I have an allergic reaction….

Your side effects would be commensurately worse with a higher dose. If 2.5mg gives you diarrhoea from the off, starting on 5mg or more might have put you in hospital.

Well then you'd be wrong.

I came off it at 5 weeks OP , mainly because I realised I didn’t need it - and if I put my mind to it can lose slowly but consistently by following the principles of what you should eat whilst on MJ as have done so before- I also didn’t like the heartburn - however being honest I was consistently losing 2lb a week most weeks whilst on it and did have mild suppression - but then I’ve got good willpower and am not a snacker, so I didn’t want huge suppression. It’s an aid , not a fat melter and different doses will suit different people

Im starting on month five, only ever used the 2.5mg, lost two stone. Been really trying to eat well, cut out wine/beer, prosecco, I’ve no intention or need to go up a dose, costs me £140 per month. I’m delighted, it’s been easier than dieting

Then why are you paying into Big Pharma?

Your side effects are EXACTLY why they can't give you a higher starting dose.

Are you also managing your calorie intake?

There is legislation in the uk to stop this from happening. 20yrs ago they reduced the “freebie” gift (ie free promotional stuff pharmaceutical drug reps used to hand out usually tat) to max £5 per Doctor- everything had to be recorded and accounted for- long gone were the expensive meals and nights away that used to be dished out. Now I believe the most they can give a doctor is a pen! So in the uk legislation means they don’t pay GP’s to prescribe anything. Also drugs have to be approved by NICE before it gets put on the British National Formulary (bnf). Prior to that, all drug trials in the uk (and Europe) have to go through local ethics committees before they can take place. There is a lot of regulation around pharmaceutical drugs. Much much more than supplements and other stuff you can buy off the shelf, or TikTok shop. Yes the big pharmas want to get money back- but it takes years and millions of pounds to get a drug on the market. Thousands of people are employed for years before they get a return. So yeah, it is expensive, and like all drugs, it may or may not work for you- but this is a drug that has been allowed to be prescribed privately to the public and it is your choice whether or not you continue with it. Also, remember, you have to work at the weight loss too. This is just an aid not a cure. This aids a calorie deficit diet not replaces it.
Im 3 weeks in, and have felt some suppression, I do feel full (not sure I did before) I’ve lost 5lb . But I also have side effects such as headache, constipation, dizziness, nausea and had those been much more intense by starting at a 5mg dose, I would have probably not taken my second jab.

I wasn't laughing at your airport predicament.

I was laughing incredulously at you moaning about the side effects at 2.5mg, then posting:

The cynic in me thinks that they start everyone at a very small dose, to get people to buy more of the drug over a longer period of time.