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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Has anyone had a good result with mounjaro?

145 replies

Marinamay44 · 01/07/2025 18:19

I thought it would be so different to what I have experienced. I thought that I would be less hungry and that I would feel fuller for longer.

Three weeks in on 2.5, I have been just as hungry as I have always been. I have felt no appetite suppresant effect at all. The only thing it's done for me are bad things: it has given me nausea and diarrohea.

I didn't think it would be like this. It is such an expensive drug too.

OP posts:
soupyspoon · 01/07/2025 19:29

Any medication wont work the same for everyone.

Some people will have side effects they can tolerate. Some people have side effects they cant tolerate
Some people respond to lower doses, some need to have more of a dose, some people wont respond to it at all.
Some people might not be able to take a particular medication for other medical reasons/contraindications.

None of the above is exclusive to WLI, it applies to any medication.

Im not able to take NSAIDs for example.

Incognitoburrito88 · 01/07/2025 19:33

I’ve had great results. I’m 12 wks in and 1lb off 2 stone loss. I stayed on 2.5mg for 6 wks. I’m now on 3.75mg. I have side effects of tiredness and nausea first thing in the morning and have found increasing my dose has increased these - I don’t think my body would have coped with a higher initial dose so I’m glad I started on 2.5mg. For me the side effects are worth it but that’s a matter of personal choice.

NeedForSpeed · 01/07/2025 19:42

Marinamay44 · 01/07/2025 19:15

I didn' expect it to miraculously remove all hunger. I expected it to have SOME effect. It is marketed as an appetite suppressant. I have felt nothing yet.

It is absolutely NOT marketed as an appetite suppressant.... It's a weight loss tool.

chipsticksmammy · 01/07/2025 19:43

Marinamay44 · 01/07/2025 19:21

And yet there are posters on here who said that they felt appetite suppressant effects in their first month?

I felt an impact about an hour after my first injection.

I have very slowly got to 15mg, it’s taken since September.

Its taken a long long time to lose the weight. It’s now down to 1 pound a month off.

The side effects had to be managed, yes there was suppression and thankfully manageable side effects but its small, slow moves on tiny dose increases and A LOT of effort on the dieting and exercise front. I mean a LOT.

I think you’re just starting a fight at this point OP.

TwoIsNewFive · 01/07/2025 19:43

Marinamay44 · 01/07/2025 18:57

Well then you'd be wrong.

If you did your reading, maybe it was somehow skewed towards the positive stories?

My understanding is that this medication has very varied acceptance and effectivity between users. Some respond at lower dosage (some even with 1.25), some at higher, some not at all.
Some people have no side effects, some have too bad to be worth it. The starting dose is testing for the side effects as well - if yours are this sever, maybe it just won't work for you. Maybe it would have been much worse if you had started with higher dose.

One thing MJ doesn't promise is consistency of effects. When you order it you are entering a lottery acknowledging that it can it happen it won't do any good for you.

Lazygardener · 01/07/2025 19:51

I'm one of the many people who had immediate results on 2.5 mg, with no side effects. I've lost weight consistently for 8 months and am now on 7.5 mg, not really intending to go any higher. So, to answer your question, yes, some people do have a good result with MJ. That doesn't mean it suits everyone. You don't seem to trust the process (or the manufacturers) so perhaps an alternative would be better for you.

WhereOnEarthIsMyPlanet · 01/07/2025 19:52

If you’ve had unpleasant side effects on 2.5mg, what do you think would have happened if you’d gone straight in at a higher dose?

Marinamay44 · 01/07/2025 19:58

NeedForSpeed · 01/07/2025 19:42

It is absolutely NOT marketed as an appetite suppressant.... It's a weight loss tool.

It absolutely IS marketed as an appetite suppressant. It is a weight loss tool because it slows digestion and suppresses your appetite

I copied a quote from online:

Mounjaro is a popular weight loss treatments.The active ingredient tirzepatide can suppress your appetite

OP posts:
Spookywoods · 01/07/2025 20:01

OP you really need to reduce your expectations and do some more research!
I have lost 7kgs since mid May. Willpower also plays a part ,particularly nearer to next dose . Being annoyed that drug companies are making money is ridiculous. Of course that will happen but for many people this medication really has made a difference to their health and wellbeing.
Edited to say that if it doesn’t work for you then just stop using it 🤦‍♀️

WhereOnEarthIsMyPlanet · 01/07/2025 20:02

Marinamay44 · 01/07/2025 19:58

It absolutely IS marketed as an appetite suppressant. It is a weight loss tool because it slows digestion and suppresses your appetite

I copied a quote from online:

Mounjaro is a popular weight loss treatments.The active ingredient tirzepatide can suppress your appetite

Key word there is ‘can’.
Anyway I’ve lost 4 stone on MJ. I had appetite suppression from the start, and lost 1 stone on 2.5mg. Doesn’t work for everyone though, which I knew from researching it before I started.

LightCameraBitchSmile · 01/07/2025 20:04

OP if you’re going to do 2 more months why not go straight to 15mg to get the most bang for your buck? Game the system if you’re feeling cheated - it’s possible with some fibs and then you’ll deny the companies the money and get the impact you want!

DiamondThrone · 01/07/2025 20:05

Marinamay44 · 01/07/2025 19:58

It absolutely IS marketed as an appetite suppressant. It is a weight loss tool because it slows digestion and suppresses your appetite

I copied a quote from online:

Mounjaro is a popular weight loss treatments.The active ingredient tirzepatide can suppress your appetite

PP said it is not marketed as an appetite suppresant. Picking up an AI quote doesn't make her wrong.

Honestly OP, you don't seem to have understood much of this.

On one thread you are complaining about the side effects at 2.5. On this thread you are complaining about nothing happending, and 2.5 being a cynical ploy by the makers.

Pick a side!

Gettingbysomehow · 01/07/2025 20:07

I've lost 5 stone since November.ber. 2.5 mgs is nothing. It's the lowest of starter doses. Of course you're not losing anything if you,ve been on that for 3 weeks you need to go up.
The pharmacy is there to advise you. Ask them and listen to what they say.

SaltAndRust · 01/07/2025 20:12

Marinamay44 · 01/07/2025 19:58

It absolutely IS marketed as an appetite suppressant. It is a weight loss tool because it slows digestion and suppresses your appetite

I copied a quote from online:

Mounjaro is a popular weight loss treatments.The active ingredient tirzepatide can suppress your appetite

Another quote from online - the manufacturer's website with prescription guidelines:

The 2.5-mg dose is for treatment initiation and is not intended for glycemic control.1 The recommended dosage escalation should be followed to reduce the risk of gastrointestinal adverse reactions.
‡Consider patient history and monitor for tolerability and side effects.

Just to make it absolutely clear - the 2.5mg is 'treatment initiation' intended to 'reduce the risk' of gastric side effects, but not expected to work. It does happen to work for some people, but for many it's just a way to start the drug with a lower risk of D&V - but that risk is still not zero.

You're really unlucky to be experiencing the adverse side effects and none of the intended effects, but that's not how it goes for most people. It's a prescribed drug, so you should always talk to your prescriber for advice.

maddiemookins16mum · 01/07/2025 20:15

I’m on week 5 on 2.5 mg. No side effects, I don’t get the urge to snack and am fuller with less food. I’ve lost 13lbs.

PinkArt · 01/07/2025 20:19

If it's not working for you and you hate giving Big Pharma money and herbal teas work better for you then why not just stop using it and drink a load of tea instead?
If anything else worked a fraction as well and cost a fraction of the amount for me then I'd jump shop in a heartbeat.

JohnTheRevelator · 01/07/2025 20:21

Watching this thread with interest. I'm on my 7th week on Mounjaro,4 weeks at 2.5 mg,now on my 3rd week at 5 mg and so far I've had zero appetite reduction. I've previously been on Wegovy and Ozempic and these both worked within 2 weeks on the lowest dose. I'm really disappointed. Thankfully,I haven't gained any weight,I've actually lost a couple of pounds but that is only through sheet will power. I have asked my provider about this and suggested that maybe I should go back on Wegovy or Ozempic but they just reassure me that I need to give it time and that in the long run, Mounjaro is the most effective weight loss injection. I'm going on the 7.5 mg dose from next week and if that doesn't do anything by the time I've done 4 weeks on it,I'm done. I will be going back to Wegovy or Ozempic. I don't know if it's a coincidence,but I've had no side effects with Mounjaro,whereas with Wegovy and Ozempic,I had fatigue,a bit of nausea and horrible 'eggy' burps. 🤢

WhereOnEarthIsMyPlanet · 01/07/2025 20:23

JohnTheRevelator · 01/07/2025 20:21

Watching this thread with interest. I'm on my 7th week on Mounjaro,4 weeks at 2.5 mg,now on my 3rd week at 5 mg and so far I've had zero appetite reduction. I've previously been on Wegovy and Ozempic and these both worked within 2 weeks on the lowest dose. I'm really disappointed. Thankfully,I haven't gained any weight,I've actually lost a couple of pounds but that is only through sheet will power. I have asked my provider about this and suggested that maybe I should go back on Wegovy or Ozempic but they just reassure me that I need to give it time and that in the long run, Mounjaro is the most effective weight loss injection. I'm going on the 7.5 mg dose from next week and if that doesn't do anything by the time I've done 4 weeks on it,I'm done. I will be going back to Wegovy or Ozempic. I don't know if it's a coincidence,but I've had no side effects with Mounjaro,whereas with Wegovy and Ozempic,I had fatigue,a bit of nausea and horrible 'eggy' burps. 🤢

Why did you stop Wegovy and Ozempic if they were both working for you?

JohnTheRevelator · 01/07/2025 20:24

Elboob · 01/07/2025 18:22

I had zero effects until I ht 7.5 mg and then the appetite suppression and "food noise" suppression that everyone talks about all kicked in. Some people only need a low dose but obviously you and I need a higher one. Keep going and you will hopefully hit a working dose soon.
(I have lost 25lb so far - slowly but not absolutely starving all the time either)

This has reassured me somewhat. Three weeks into 5 mg and still no appetite reduction. I'm hoping that the 7.5 mg does it for me!

Titasaducksarse · 01/07/2025 20:24

Marinamay44 · 01/07/2025 19:58

It absolutely IS marketed as an appetite suppressant. It is a weight loss tool because it slows digestion and suppresses your appetite

I copied a quote from online:

Mounjaro is a popular weight loss treatments.The active ingredient tirzepatide can suppress your appetite

Where is this evidence from, as, if you look on the manufacturers website it doesn't actually state this.

JohnTheRevelator · 01/07/2025 20:27

WhereOnEarthIsMyPlanet · 01/07/2025 20:23

Why did you stop Wegovy and Ozempic if they were both working for you?

I had to stop because of financial reasons. I was taking Ozempic 2 years ago and Wegovy a year ago and both times it started to get too expensive (Christmas and birthdays and holidays coming up). Once I'd got myself straight money wise,I changed supplier as I was fed up with my previous one ignoring my emails and messages and my new provider recommended I start on Mounjaro. So I did!

nomoreredtape · 01/07/2025 20:32

If you do a little digging, you’ll discover the drug company is making huge profits but it’s not on mounjaro alone, it’s actually the pen. Mounjaro itself is a synthetic peptide and isn’t really all that valuable to pharmaceutical companies but when combined with an injector pen, it becomes worth their while. They don’t make substantially more money the higher the dose because the biggest margin is in the pen itself. So your theory about low doses and them trying to push you up to higher doses for financial gain isn’t accurate.

As others have said, 2.5mg is a loading dose and every bit of research I’ve read states you shouldn’t expect too much from it. It worked for me, for the first 3 weeks but by week 4, I knew I needed something with a bit more oomph. I’m now on 5mg and that’s working as it should.

If you don’t like it and feel like you’re being tricked by big pharma, it’s best to stop taking it.

Marinamay44 · 01/07/2025 20:36

DiamondThrone · 01/07/2025 20:05

PP said it is not marketed as an appetite suppresant. Picking up an AI quote doesn't make her wrong.

Honestly OP, you don't seem to have understood much of this.

On one thread you are complaining about the side effects at 2.5. On this thread you are complaining about nothing happending, and 2.5 being a cynical ploy by the makers.

Pick a side!

It IS marketed as an appetite suppressant.

How can you lie like that.

Of course it is marketed as an appetite suppressant.

Every article about it online says that it is an appetite suppressant.

OP posts:
Marinamay44 · 01/07/2025 20:44

This is from Boots online doctor.

Mounjaro is a weekly self–injectable pen used for weight loss. It contains tirzepatide which works by regulating blood sugar and energy balance levels, helping to reduce appetite and prevent cravings.

Absolutely everywhere says that it is an appetite suppressant.

OP posts:
NeedForSpeed · 01/07/2025 20:45

Marinamay44 · 01/07/2025 19:58

It absolutely IS marketed as an appetite suppressant. It is a weight loss tool because it slows digestion and suppresses your appetite

I copied a quote from online:

Mounjaro is a popular weight loss treatments.The active ingredient tirzepatide can suppress your appetite

CAN is not WILL.