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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro hasnt worked

110 replies

Melonjuice · 31/05/2025 10:20

I lost nothing in 4 weeks on first dose . Waste of money . I ate in a calorie deficit also and excersized
If the whole point of this medication is just to stop you from feeling hungry and suppress appetite rather than actually medically working to help you lose weight then it’s pointless because if I eat in a calorie deficit without it I’d lose weight anyway ?
Quite disheartening. Started at 12 stone finished at 11.13 stone. What am I doing wrong ? At this point I’m going to start eating cotton wool !

OP posts:
BeKindOpalBear · 31/05/2025 10:58

SnacklessWonder · 31/05/2025 10:54

Is my maths not mathing.

Started at 12 stone finished at 11.13 stone.

Surely you've lost 12lbs?

your math definitely not mathing! it is a one pound loss for the OP

soupyspoon · 31/05/2025 10:59

SnacklessWonder · 31/05/2025 10:54

Is my maths not mathing.

Started at 12 stone finished at 11.13 stone.

Surely you've lost 12lbs?

1lb

usedtobeaylis · 31/05/2025 11:02

If you're exercising you might not be eating enough. If you keep doing that it will come off, but not in a healthy way. That might be the cause of your light headedness. Definitely look up your TDEE, it's really simple. I'm also 5' 6" and my TDEE is around 2000 calories, so I eat 1500 and track it. It works.

SnacklessWonder · 31/05/2025 11:02

Ohhhhh I wasn't reading it as 11 stone 13lb.

I was reading it as 11.13 stone 😆

xanthomelana · 31/05/2025 11:06

I lost nothing until I started 7.5mg then the weight came off but still not as fast as others. I’ve lost 5 stone in a year though and I wouldn’t have been able to do that by myself. One thing I’ve learned is don’t compare yourself with others because everyone has a different journey.

Doyouthinktheyknow · 31/05/2025 11:12

@Melonjuice I basically did what you have done but without the injections and I’ve lost more than 2 stone so it is possible.

I’ve done intermittent fasting, 16/8 and cut out snacks. I started at 13.1lb, the same height as you and I was still slightly under the qualifying BMI for the injections!

Try intermittent fasting, it’s been amazing for me. I workout 4 times a week minimum too.

wlinewbie0425 · 31/05/2025 11:13

I am your height and am also wondering how you obtained Mounjaro. Not judging, I understand on a lot of frames 12stone still can look and feel a lot more than a healthy weight and I too want to get a lot lower than that, but unless you have a condition you’ve not mentioned you are quite a bit lower than the standard required BMI. BMI of 30 at our height is around 13stone 4. at 12 stone it would only be around 27 so maybe you have additional conditions that your prescriber accepted or certain ethnicities also.

I think it’s likely to be a combination of not having as much to lose, and actually doing quite a bit of exercise changing your fat to muscle. Plus you are possibly a slower responder to the drug and will see a difference when you get up to correct dose.

did you take measurements? If not you can also use the app called methreesixty to do a body scan. People often see the difference in inches rather than scales at different times.

you only have to dip into the many threads to see that this drug demonstrably does work for most people - but at very different rates and not for everyone. You can’t know yet though, the 2.5 was meant to be a gradual taper up dose, it’s just so happened that with more and more users many have now shown it can be effective for some.

NoAprilFool · 31/05/2025 11:31

It sounds like you’re not eating enough to keep a hamster alive.
do track your calories - to make sure you’re eating enough!

Crikeyalmighty · 31/05/2025 11:40

@NoAprilFool interesting that - I had a couple of days on MJ where I only ate around 850 cals as had awful heartburn and I gained a kilo - upped it to 1250 and it went again within 3 days - I do think not eating ‘enough’ can be a real issue ‘for some’ - it’s a fine balance

IsItSnowing · 31/05/2025 12:28

Most people who don't lose weight are not in a calorie deficit. It's very easy to think you're eating practically nothing but still consuming too many calories.
I'd drop the oil before I got rid of the carbs personally but it's your choice how you want to eat. It's all about calorie deficit, however you want to get there, whether it's low carb or whatever type of eating plan you choose. But oil and salad dressings have a lot of calories even in a very small portion.

Golidlocksandthethreeswears · 31/05/2025 12:29

Melonjuice · 31/05/2025 10:48

Hello I am 5’6 was 12 before now 11.13
diet before hand was terrible ( depression combined with very inactive sit down stressful job) usually Sainsbury’s ready meals , occasional home cooking chicken thighs potatoes, rice steaks and chips - I didn’t track calories
i’m now eating just two meals a day a small salad for lunch ( just salad veg) and a dinner consisting of salad a meat ( say chicken breast or lean steak ) with boiled new potatoes - but this is a child’s portion
excerrsize bike at home and sit ups

I have started feeling dizzy, and the 2.5 mg dose is giving me very bad bloating and distended tummy throughout the day . I also have really bad constipation.
I’m going to try the 5 mg and actually do some calorie counting. I didn’t bother to do it because I’m eating so little . I’m probably going to buy some laxatives as well.

How did you qualify for Mounjaro with a bmi of 27? Have you got it from a legit source, because if not you could be injecting anything into your body.

If you aren't accurately logging/tracking your calorie intake, you are probably consuming far more than you realise. I can easily make a salad which ticks all the healthy boxes by sight, but comes in at almost 1000 calories. You should do this for a few weeks to get a good idea of where you are before looking to increase, assuming you should be on it in the first place.

SilenceInside · 31/05/2025 12:36

You can qualify legitimately for Mounjaro with a BMI of 27 if you are one of a list of certain ethnicities where obese is classified as a BMI of 27 or higher. Also if you have one or more weight related health conditions.

As lots of other people have said, @Melonjuice, it’s a long term process. 2.5mg does not produce significant weight loss for most, hence the typical dosing schedule to move to 5mg after 4 weeks. I would only say that Mounjaro definitively isn’t working for you if you’ve got to 4 weeks of the top 15mg dose and still not lost any significant weight at all. That’s many weeks away.

soupyspoon · 31/05/2025 17:11

Crikeyalmighty · 31/05/2025 11:40

@NoAprilFool interesting that - I had a couple of days on MJ where I only ate around 850 cals as had awful heartburn and I gained a kilo - upped it to 1250 and it went again within 3 days - I do think not eating ‘enough’ can be a real issue ‘for some’ - it’s a fine balance

That is just natural fluctuations. I fluctuate hugely. On Wednesday morning I was 11 stone. Today I am 10.7lb

No reason, just up and down, up and down. Weather related probably.

Singlemomofthree · 01/06/2025 16:12

You’re still eating more calories than you’re burning. Weight loss is simply calorie in vs calories out no matter what diet or supplement you take. 56lb loss with the help the mounjaro and team rh. You need to fix your eating habits and not expect just to drop fat because you’re injecting glp1 medicine

Plumnora · 01/06/2025 16:12

2.5mg is a loading dose. When you go to 5mg which is a maintenance dose, you should see some results.
I'm 5ft nothing and was 14st12 when I started in February. I'm 12st10 now. I still have a lot of weight to lose but it's been slow. It's sounds as though you weren't that overweight to begin with and weight loss is always slower the less you have to lose. Stick with it, trust the process and it'll start coming off.

Presterjohn71 · 01/06/2025 16:18

You're almost certainly cheating. My wife is also on a version of this drug and is also moaning about it not working. She also thinks she's eating sensibly. I catch her cheating all the time and she always has an excuse. You can't spend your way into losing weight. You still have to do the work.

Frugalgal · 01/06/2025 16:20

The point of Mounjaro is to make you eat less, it does not in any way medically melt fat off you, as you seem to expect.

And yes, if you eat in a calorie deficit you should lose weight with or without it. But 'without' is easier said that done for most people.

The point of it is to supress your appetite so that you can re-train yourself into better habits than what presumably got you to a position of needing MJ in the first place. I'd be very surprised if you said this was your first attempt at weight loss , so why didn't those other attempts work?

Remember you have been on a non-thereutic dose to get your body used to the drug , it's not necessarily meant to work that well at this dose, although it does for many, including me.

Try the next dose up before you give up. While MJ is miraculous for some (including me, it's killed my temptations stone dead, I had a serious wine habit which just instantly went) it can cause others hideous side effects even at the lowest dose and then for up to one in four people it doesn't work at all.

Try the 5mg before you give up, but if you can stick to calorie deficit without it without falling off the wagon just do that . If I could do what MJ is helping me to do without injecting myself with an expensive drug, I certainly would.

SprinkleTheCat · 01/06/2025 16:28

What are you drinking.. Any high calories drinks?
Also are these loaded salads.. E.g loaded with dressing, oil, cheese, meat etc. It's shocking how many calories can be in a salad they are not empty calories.
I would think if you are not losing weight you are simply not in a calorie deficit.

bumblebee3122 · 01/06/2025 16:28

The 2.5mg dose is just to get you used to the drug. Its not a therapeutic dose. That's 5mg and above. I didn't feel any restriction until 5mg

JuliaLilian · 01/06/2025 16:29

That’s a 1lb loss not a stone loss. 12 stone down to 11 stone 13.

Blondeshavemorefun · 01/06/2025 16:29

Melonjuice · 31/05/2025 10:48

Hello I am 5’6 was 12 before now 11.13
diet before hand was terrible ( depression combined with very inactive sit down stressful job) usually Sainsbury’s ready meals , occasional home cooking chicken thighs potatoes, rice steaks and chips - I didn’t track calories
i’m now eating just two meals a day a small salad for lunch ( just salad veg) and a dinner consisting of salad a meat ( say chicken breast or lean steak ) with boiled new potatoes - but this is a child’s portion
excerrsize bike at home and sit ups

I have started feeling dizzy, and the 2.5 mg dose is giving me very bad bloating and distended tummy throughout the day . I also have really bad constipation.
I’m going to try the 5 mg and actually do some calorie counting. I didn’t bother to do it because I’m eating so little . I’m probably going to buy some laxatives as well.

So your bmi is under 30

sounds like you have suppression if eating 2small meals but equally maybe not eating enough and body thinks being starved

many don’t get any proper results till 10 +

Horserider5678 · 01/06/2025 16:33

Melonjuice · 31/05/2025 10:26

thanks all ill try the 5mg and see if that makes a difference
I’ve just been eating ( and craving ) mainly salads with a bit of protein and a veg side
I’ll prob cut out potatoes and other carbs totally and go to the gym rather than excersize at home and see how that goes x

You need a diet high in protein and reduce the carbs. If you don’t eat a balanced diet then your body goes into starvation mode!

You need to realise it’s not a quick fix, I’ve lost 3 stone starting in wygovy then moving to mournjaro, however it has taken 2 years!

TheArtfulNavyDreamer · 01/06/2025 16:34

2.5mg isn’t a therapeutic dose and if you have blood sugar issues it seems to correct those before the weight loss effects kick in for people so usually on the later doses. If you feel dizzy you need to eat more and do you seriously only want salad? I eat all my usual meals just smaller portion sizes.

Titasaducksarse · 01/06/2025 16:37

If you read up on it, 2.5mg is just to get you used to it and you're not expected to lose weight but it's unfortunate many do and you see the 'I lost a stone a month' posts.
I'm 4 months in and losing nowhere near that much but it's coming off slowly and steadily.

MyRootinTootinBaby · 01/06/2025 16:38

You need to actively count the calories. In the past, I’d assumed I was in a calorie deficit at 1800 cals, but when I worked it out I needed to be at 1350 cals to lose weight. It all adds up.