Meet the Other Phone. Flexible and made to last.

Meet the Other Phone.
Flexible and made to last.

Buy now

Please or to access all these features

Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

I don't understand weight loss injections. I have questions

251 replies

nevertuesday · 22/03/2025 07:15

Google tells me that people loose 10% of their body weight over a year. so if you started at 100kg, you would be 90kg after a whole year!! that is not good weight loss at all. definitely not worth, what it costs

but people loose significantly more than that, don't they?? certainly people on social media have definitely lost more than 10% and in a shorter space of time

2nd question from a place of considering trying it because I have mobility issues and it would really be beneficial to not be over weight. but, I don't particularly eat loads and loads. I have a sweet tooth and I emotionally eat, I'm not eating because I am hungry. so am I correct in thinking that it probably wouldn't help me much?

OP posts:
PinkArt · 31/03/2025 23:29

nevertuesday · 31/03/2025 22:03

thank you for taking the time to find the electronic version. I found the leaflets as you described.

I have taken the first dose. excited to see what happens! does it take effect straight away? as in, tomorrow I won't crave chocolate all day?? it's hard to believe

It's impossible to predict. Some people it is very effective from day one, some people notice no effects for a month or more

Seaitoverthere · 01/04/2025 06:47

Overhaul54 · 31/03/2025 22:54

Does it though?
We all know the human chemistry is set to respond to fat and sugar. That’s everyone not just the obese. Eating too much or highly palatable food is easier than not.
Thin people very often make a conscious choice not to eat too much and avoid certain foods.

Stopping food noise is a revelation but it’s unfair to say it’s because fat people are somehow more challenged around food than thin people. It is like smoking. If you think fags are disgusting you don’t smoke. If you think it’s quite fun or cool you might start. And then blame nicotine for being addicted.

If you don’t think it’s ok to have a doughnut or a plateful of food you don’t and consequently are less likely to miss something you don’t eat.

I think for some people it gives a sensation of being full that can be missing, it has for me. I’ve always struggled with this since childhood and it has been a bit of a revelation taking Mounjaro this year. It’s like a switch goes on at a certain point and I know that’s enough, just as my DH and DC have always done.

I am capable of losing weight without it , lost over a 100lbs a few years ago but sadly an injection of Prostap pre hysterectomy and a couple months of HRT and a significant chunk went back extremely quickly (33lbs in 11 weeks with the Prostap) despite no change in food intake or exercise which were carefully monitored to enable me to lose 107lbs in the first place.

GnomeDePlume · 01/04/2025 06:49

Mounjaro has a physiological effect. It stimulates the body to release more insulin and the liver to release less glucose. That is how it works to treat T2 diabetics.

Lots of people talk about 'food noise' but we aren't all necessarily talking about the same thing. If part of your food noise is coming from poorly regulated blood sugar then mounjaro is probably going to help with that.

So much of weight management is talked about in absolutes. People are diabetic because they are fat. People are slim because they have more discipline.

I think what the results of mounjaro are showing is that it isn't as simple as that. It will help with the physiological elements, remove the food cravings caused by unstable insulin. It won't burn the fat off. It is just helping people who are overweight to make better choices.

I'm on mounjaro because I am a T2 diabetic with unstable blood sugar. As a result of being on mounjaro I have been able to lose 3 stone. I still have a lot more to lose (probably another 9 stone) to get into a healthy BMI. But being on mounjaro means I am not fighting my blood sugar at the same time as sorting out my diet.

BettyandtheVets · 01/04/2025 07:07

Apologies if someone has already said as I confess to not having read the whole thread but take some time out today to do your measurements. I’m a slow looser but I love to see how many cm’s I’m loosing in addition to seeing the weight reduce.

nevertuesday · 01/04/2025 08:53

BettyandtheVets · 01/04/2025 07:07

Apologies if someone has already said as I confess to not having read the whole thread but take some time out today to do your measurements. I’m a slow looser but I love to see how many cm’s I’m loosing in addition to seeing the weight reduce.

it has taken an inordinate amount of time and effort to finally get on the scales this morning. I haven't weighed myself for around 3 years! I think taking Ng body measurements is a great; dea, I will do that later too

OP posts:
PinkArt · 01/04/2025 09:28

I'd add taking Photos Of Doom to the measurements suggetion. Mine are side on, front on and an honest selfie that doesn't try to flatter the chins. They're really helpful for noticing the more subtle changes.

nevertuesday · 01/04/2025 09:40

PinkArt · 01/04/2025 09:28

I'd add taking Photos Of Doom to the measurements suggetion. Mine are side on, front on and an honest selfie that doesn't try to flatter the chins. They're really helpful for noticing the more subtle changes.

oh crikey, one step at a time, eh??! not ready for that yet 😬

OP posts:
nevertuesday · 01/04/2025 09:42

I haven't wanted breakfast yet! normally I would be craving sugar by now and trying to resist going to get pastries from Lidl. it's very subtle and possibly placebo, I don't feel nauseous

OP posts:
shrinkingthiswinter · 01/04/2025 11:08

@nevertuesday that’s it! Just a gentle shift. You need to pay attention to it, notice the quicker fullness, make better choices, and the weight falls off! Eating something protein-rich rather than sugary for breakfast helps for the rest of the day.

PinkArt · 01/04/2025 11:35

nevertuesday · 01/04/2025 09:40

oh crikey, one step at a time, eh??! not ready for that yet 😬

Ah but that first one - which you will hate! - becomes so valuable once you compare it to later ones. I hold a lot of weight on my tummy and didn't think it was improving much, as I look down and it's still very there, but between November and now it's definitely changed. It sticks out a lot less but I can also see where my waist is returning, more shape to it rather than just a giant balloon. Same with my face. The chin is still very much present but when I compare November to now I can see how much it's actually decreased.
Clearly no-one else must ever see any of of them, but purely as record keeping I've found them really helpful.

GnomeDePlume · 01/04/2025 11:38

nevertuesday · 01/04/2025 09:42

I haven't wanted breakfast yet! normally I would be craving sugar by now and trying to resist going to get pastries from Lidl. it's very subtle and possibly placebo, I don't feel nauseous

If you feel hungry have a drink. It may not be hunger but thirst.

nevertuesday · 01/04/2025 12:02

PinkArt · 01/04/2025 11:35

Ah but that first one - which you will hate! - becomes so valuable once you compare it to later ones. I hold a lot of weight on my tummy and didn't think it was improving much, as I look down and it's still very there, but between November and now it's definitely changed. It sticks out a lot less but I can also see where my waist is returning, more shape to it rather than just a giant balloon. Same with my face. The chin is still very much present but when I compare November to now I can see how much it's actually decreased.
Clearly no-one else must ever see any of of them, but purely as record keeping I've found them really helpful.

you're right, you're right. I will take some later. how horrifying 🥹

OP posts:
nevertuesday · 01/04/2025 12:04

shrinkingthiswinter · 01/04/2025 11:08

@nevertuesday that’s it! Just a gentle shift. You need to pay attention to it, notice the quicker fullness, make better choices, and the weight falls off! Eating something protein-rich rather than sugary for breakfast helps for the rest of the day.

I just had a tuna salad. when I started eating it, I thought I would scaff the lot and probably have a 2nd bowl. I ate about 3/4 of it and didn't want the rest. still waiting for the familiar craving for a week treat to finish it off 🤷🏼‍♀️

OP posts:
PinkArt · 01/04/2025 14:00

nevertuesday · 01/04/2025 12:02

you're right, you're right. I will take some later. how horrifying 🥹

If you use Google photos for storage you can set up a secret/ hidden folder. Not only would no-one else be able to see them, you won't unless you only go into the folder. As much as I find them useful, I don't want to accidentally see one of the horribly honest pics as I'm heading out thinking I look ok!

InfoSecInTheCity · 01/04/2025 14:39

@PinkArti do the same in my Apple photos, they are in a hidden folder, password protected that takes effort to access.

peppercornrent · 01/04/2025 19:00

nevertuesday · 01/04/2025 12:02

you're right, you're right. I will take some later. how horrifying 🥹

Surely you'll have the photographs that you took to get your prescription ?

LolaLouise · 02/04/2025 09:48

Overhaul54 · 31/03/2025 22:54

Does it though?
We all know the human chemistry is set to respond to fat and sugar. That’s everyone not just the obese. Eating too much or highly palatable food is easier than not.
Thin people very often make a conscious choice not to eat too much and avoid certain foods.

Stopping food noise is a revelation but it’s unfair to say it’s because fat people are somehow more challenged around food than thin people. It is like smoking. If you think fags are disgusting you don’t smoke. If you think it’s quite fun or cool you might start. And then blame nicotine for being addicted.

If you don’t think it’s ok to have a doughnut or a plateful of food you don’t and consequently are less likely to miss something you don’t eat.

Its not unfair, its fact. It has been biologically proven, that in some people, the GLP1 hormone receptors are less responsive than in others. GLP1 does a number of things, but simplistically, it signals our brain when we are full and to stop thinking about food, when the receptors stop receiving the message, we are hungry, and start thinking about food. In many overweight people, the physical feeling of full occurs, but the message to stop thinking about food doesnt. Its overwhelming, loud, there or the time, or its a background whisper constantly gnawing away. Its not just sweets and cakes that make people obese, its all foods, or sometimes not even foods at all, in my case it was drinks. In people whos receptors work well, they may be able to resist having that second helping of dessert, a chocolate bar when they pop to the shop, or a pastry on their morning commute, or a daily frappucino, because it isnt a constant noise in their head. Being able to actively chose not to do something is much easier when its occasional, not constant. Its the same battle, yes, but the frequency is different. This difference in how receptors respond is medically proven, and why MJ works for emotional, reactive eating. Because when those feelings are overwhelming, the noise saying have food is no longer there, so you find other coping mechanisms. A lot of people on MJ are taking up more exercise too, because they have the clarity to be able to make that decision without this noise shouting "food" at them all the time, or more mindfullness type hobbies etc.

Yes it works with insulin as well, but this response to GLP1 and making receptors hypersenstive, instead of barely reacting, is why it is also licensed for weightloss alone and not just for diabetics, because it "fixes" a genetic, biological difference in people, one that directly causes obesity.

MarginallyOk · 27/04/2025 17:13

I’m uhming and ahhing about starting MJ. I’m about 4 stone overweight and I really want to get in shape but ‘food noise’ defeats me every time. I’m able to eat in a disciplined way during the week, no bother but then Friday comes along and out comes the wine and takeaway and it doesn’t stop till Sunday night. Consequently I never lose anything but on Monday, I rinse and repeat and convince myself ‘this week will be different’. But of course it never is.

My main concern is that I read somewhere it can increase your heart rate. I don’t have any heart problems but I do get anxious with my heart rate, to the point I had to switch the monitor off on my watch! Has anyone experienced an increased heart rate?

ThirstyAndTired · 27/04/2025 17:30

MarginallyOk · 27/04/2025 17:13

I’m uhming and ahhing about starting MJ. I’m about 4 stone overweight and I really want to get in shape but ‘food noise’ defeats me every time. I’m able to eat in a disciplined way during the week, no bother but then Friday comes along and out comes the wine and takeaway and it doesn’t stop till Sunday night. Consequently I never lose anything but on Monday, I rinse and repeat and convince myself ‘this week will be different’. But of course it never is.

My main concern is that I read somewhere it can increase your heart rate. I don’t have any heart problems but I do get anxious with my heart rate, to the point I had to switch the monitor off on my watch! Has anyone experienced an increased heart rate?

Not me. No heart rate problems!

I've been on mounjaro since Jan 1st and lost 25% of my body weight already!

Hardly any side effects, just a bit thirsty, tired and cold. But now I'm getting nice and slim I have started working out, running, swimming more and I feel great!

OP - how's it going?

nevertuesday · 27/04/2025 18:18

LolaLouise · 02/04/2025 09:48

Its not unfair, its fact. It has been biologically proven, that in some people, the GLP1 hormone receptors are less responsive than in others. GLP1 does a number of things, but simplistically, it signals our brain when we are full and to stop thinking about food, when the receptors stop receiving the message, we are hungry, and start thinking about food. In many overweight people, the physical feeling of full occurs, but the message to stop thinking about food doesnt. Its overwhelming, loud, there or the time, or its a background whisper constantly gnawing away. Its not just sweets and cakes that make people obese, its all foods, or sometimes not even foods at all, in my case it was drinks. In people whos receptors work well, they may be able to resist having that second helping of dessert, a chocolate bar when they pop to the shop, or a pastry on their morning commute, or a daily frappucino, because it isnt a constant noise in their head. Being able to actively chose not to do something is much easier when its occasional, not constant. Its the same battle, yes, but the frequency is different. This difference in how receptors respond is medically proven, and why MJ works for emotional, reactive eating. Because when those feelings are overwhelming, the noise saying have food is no longer there, so you find other coping mechanisms. A lot of people on MJ are taking up more exercise too, because they have the clarity to be able to make that decision without this noise shouting "food" at them all the time, or more mindfullness type hobbies etc.

Yes it works with insulin as well, but this response to GLP1 and making receptors hypersenstive, instead of barely reacting, is why it is also licensed for weightloss alone and not just for diabetics, because it "fixes" a genetic, biological difference in people, one that directly causes obesity.

I did not know this. or, I hadn't thought about it like that. it's true.

I was a very healthy weight most of my life. i didn't have to make conscious decisions to not eat too much/the wrong foods at all. I don't know how the science explains why someone develops the food noise later in life but mine has been the last 10 years. it has been CONSTANT

OP posts:
nevertuesday · 27/04/2025 18:24

ThirstyAndTired · 27/04/2025 17:30

Not me. No heart rate problems!

I've been on mounjaro since Jan 1st and lost 25% of my body weight already!

Hardly any side effects, just a bit thirsty, tired and cold. But now I'm getting nice and slim I have started working out, running, swimming more and I feel great!

OP - how's it going?

hi, I have lost 3.8kg (8.4lb)in 3 weeks. it has been so easy! I'm so happy I decided to try it. however, I'm struggling a bit these last 2 or 3 days. I'm coming to the end of my 4th week so about to go up to 5mg. I am hoping that dose increase will return me to how it felt for the first 3 weeks in 2.5mg. a week ago I was thinking that I don't need to increase my dose because my appetite was well controlled on 2.5mg but I really feel a drop off in effectiveness now. I am a bit nervous that is the end of that 🫤 I'll be so disappointed because these 3 weeks have been so fantastic

OP posts:
Worriedmotheroftwo · 27/04/2025 22:08

MarginallyOk · 27/04/2025 17:13

I’m uhming and ahhing about starting MJ. I’m about 4 stone overweight and I really want to get in shape but ‘food noise’ defeats me every time. I’m able to eat in a disciplined way during the week, no bother but then Friday comes along and out comes the wine and takeaway and it doesn’t stop till Sunday night. Consequently I never lose anything but on Monday, I rinse and repeat and convince myself ‘this week will be different’. But of course it never is.

My main concern is that I read somewhere it can increase your heart rate. I don’t have any heart problems but I do get anxious with my heart rate, to the point I had to switch the monitor off on my watch! Has anyone experienced an increased heart rate?

Do it! I've lost more than 4 stone on MJ in 6 months. Just think - by Halloween you could be at your goal weight, 4 stone down!

Not noticed any heart related issues. I do have a fast heart rate anyway, and it can get very high while exercising (I wear a fitbit so can monitor) but not noticed any worse. Next time I do parkrun I'll keep an eye and see if it's improved!

shrinkingthiswinter · 27/04/2025 22:19

Nothing is going to help your heart health as much as being a healthy weight.

LindtCurves · 27/04/2025 22:43

redphonecase · 22/03/2025 07:17

I've lost >20% of my starting weight in 6m. (from just over 100 to just under 80kg)

Same, 20% in 6 months.

It's also made me feel loads better and healthier in so many ways. I love it.

I can literally have a delicious dessert in the fridge for weeks and weeks, or chocolate bars in the drawer, I eat them like any other food, no emotional/ comfort/ boredom eating. I mostly eat to actually feed my body with the good stuff now!

I also thought i didn't eat too badly before, but it has definitely changed something in my body, for example triggering the loss of almost all excess visceral fat.

I'd say try it, nothing to lose really.

ThatWardrobe · 28/04/2025 11:41

My heart rate went up a bit, but it turned out I was taking waaaayyy too much levothyroxin for someone who'd lost 40lb in 3 months - sorting that issue out now and feeling back to normal. I think most of the issues you read about are actually attributable to something else. Eg I gather there's a known issue with gallstones (I've not had this), but that comes with fast weight loss from any method, it's not because of Mounjaro.