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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

January 2025 Starters Thread 5 - Tortoises, Slow Runners, let’s lose a bit more!

984 replies

DGonMJ · 26/02/2025 20:29

Previous thread https://www.mumsnet.com/talk/weight-loss-injections/5270287-january-2025-starters-thread-4-lets-lose-some-more

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OP posts:
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28
Upperroom · 05/03/2025 22:29

JoanCollinsDiva · 05/03/2025 22:01

I totally relate.

Also to this: think MJ is having a slight negative effect on my mental health - low energy and a bit “blank”… does that make sense?

Ive felt quite low mood/energy from the start apart from the first week when I felt great. My mood has definitely perked up since we've had a few sunny days though and I've been making sure to get out in it as I'm sure it's also vit D related.
I think it's to do with the "joy" receptor being dulled maybe in regards to food? Apparently one of the widespread effects of WLI's being the reduction in dopamine-fuelled behaviours. So I've also not been drinking or smoking (was only a two a day habit but still) or drinking coffee - so it's like all the things that gave me a little thrill are gone! Obviously it's for the best but it makes sense that life maybe feels a bit more boring now..

I previously loved having a nice curry at the weekend and then eating some really nice food from Waitrose on a Saturday night followed by a few glasses of wine. I can't stomach that now and dont really enjoy the taste of very much so it's a bit as you say...meh. It's definitely the lesser of two evils though - I couldn't continue just slowly gaining weight and on balance I was miserable before I started taking it. I'd rather be slim and a bit miserable than fat and very miserable 😂

This is so interesting @JoanCollinsDiva
I've felt very flat this week despite amazing sunny weather and good weight loss. Makes sense re the dopamine hit is no more in food/treats. I’ve felt tired too but wasn’t sure if that was to do with previous week work stress plus I’m peri..
i really loved the first week too. I wonder if when I’m on a maintenance dose (maybe 2.5 monthly) I’ll get that back?

TheCatsBlanket · 05/03/2025 23:25

Zempy · 05/03/2025 09:48

I’m not losing any weight, but I haven’t 💩 for about four days now.

I drink so much water, taking stool softeners and dulcolax. I think I will have to take two dulcolax tonight. Grim.

I’m also struggling with not 💩ing and it’s making me feel very uncomfortable. Taken some senokot tonight so hopefully there’ll be a welcome explosion in the morning! Thankfully it’s my day off tomorrow so I can poo freely. I’m not going to weigh myself until I’ve had a good blowout

HeavyHeidi · 06/03/2025 05:34

The number of hypermobile people on this thread is really interesting. Also something you might want to look into - I found some studies where they speculated that it might be related to gene defect that doesn't allow us to metabolise folate properly. So blood would show elevated folate levels, but it just circulates there. I started supplementing with methylated folate about a year ago and now when we were discussing hypermobility, tried my usual party tricks. And my thumbs do not bend comfortably against my arm any more - could of course be age related, but could be the folate.

800gr loss this week. Not loads, but I've lost several cm all over, so not complaining. Overall, that's 10 kilos gone since January 6th - 7.5 on MJ. Shot day as well, will remain with 2.5.

Zempy · 06/03/2025 05:57

I mean, statistically it’s bizarre that so many of us are hyper mobile!

There has to be something in it surely?

I have managed a small victory on the 💩 front and off to London now…

RockyisMYRhino · 06/03/2025 06:31

Weigh in and jab day today and I've pretty much stayed the same again 😞 bringing me to a loss of a stone since 9 jan which I can't help but be a little disappointed by even though it's a stone I wouldn't have lost on my own as I would have got bored of a diet by now. Fingers crossed for a 'proper' loss next week!!!

HeavyHeidi · 06/03/2025 06:49

@RockyisMYRhino exactly, of course we have actually lost the weight ourselves by eating less, it's not like the jab is magically melting fat. But I would have felt massively deprived the whole time and looking forward to the end of the diet, so I can eat 'normally' again.
This time is different.

BreezyPeer · 06/03/2025 07:05

So interesting to read how many people are hypermobile! Not me, fascinating though.
Weigh and jab day today so sad as its a STS for me. Giving myself a talking to right now as I am not Obese for the first time in years, just seems a bit of a plateau. Period should be here within the next few days so I wonder if its that?
Also . . . This is the first week I haven’t tracked my calories so that is obviously important for my success. Still haven't had any chocolate, sweets, cakes etc
I've done 3.75 again as my suppression does seem good but I will top up to 5 later in the week if needed.
Good luck to anyone else weighing today😀

Howinthehelldidthishappen · 06/03/2025 07:38

Morning all.
Week 10 day 1 here. Going to take my bonus dose of 5mg later.
I'm a daily weigher, and it has been up and down by 2-3 pounds all week, and wasn't convinced I'd see a loss, but I do believe I've just entered a new stone bracket!
I haven't done my measurements yet today, getting up at 4am is hard enough without fussing with a tape measure that my cat constantly tries to sink his claws into.
Still no real side effects, period dragged on a couple of days longer than normal, but very very light for those days.

STATS TIME
SW 214.3lbs
CW 181.2lbs
GW 168lbs

Seaitoverthere · 06/03/2025 07:55

I think my hips were hypermobile but no other joints. However DD has many joints that are. Interesting about the folate, I take methylated folate with B12 these days.

Congratulations on being over weight @BreezyPeer !

Mounjaro hasn’t affected my mood but it definitely is affecting my cousin who has said a few times that all the joy has gone from her life. She was ok with it at first but loss has slowed down hugely and I think she is now feeling pretty pissed off.

MananaMananaPenelope · 06/03/2025 08:09

Morning all, I think my mood is affected, but work is pretty 💩 for me at the minute so that’s probably having an impact.

Daily weigher here, last night I weighed almost 2kg more than I did on Sunday evening, this morning I’m at 98kg which is .2 or .4 kg up on the weekend. It isn’t an exact science is it, I’ve eaten about 950 cals a day this week. Drinking loads. Psyllium husk is doing its daily job so I’m no longer constipated at all.

I never know what to expect when I step on the scales.

JSGMJ · 06/03/2025 08:29

Hi first time poster here but long time lurker. Reading posts on here helped me decide to join you on this weight loss journey. These past few years I've piled on weight from being over weight to obeses due to hip and joint problems affecting my mobility. Having been previously very active, cycling walking gardening etc to barely being g able to walk 100 meters . So I've recently had a total hip replacement in October and am now feeling more mobile I've decided that the best thing I could do for my health was to lose weight. I watched the video someone posted a link to on here somewhere that gave me the confidence to get started even though I can't really afford this its worth it in the long term .
So I started in January at the highest weight I've ever been
Sw 15st 11ib
Cw 14st 10 lb
Gw 11st 6
So far I've done 4weeks at 2.5 mg
and 4 weeks of 5mg and am about to use a 7.5 mg pen to give me 5 weeks of 5mg to stay on the same dose. I'm feeling rather tired and cold and constipated with sulfur burps so figure staying on this dose will be for the best at the moment . I've averages 1.6 lb loss a week although I had three weeks of no loses which was disappointing but nice figured was still helping me in other ways so stuck to it. My clothes fit better and I've lost 2inches from my hips and 1 from my waist so far. So my slow but steady weight loss will hopefully see me lose another 2 stone by the summer holidays. And I will hopefully be at my goal weight by Sept . My only worry is how to maintain my weight once I'm off this medication. I see that my appetite is completely disregulated and I easily put on around 1 lb a month if left unchecked even with lots of exercise which I'm struggling to do at the moment with recovery from my hip operation and other arthritis issues. Given that I'm only in my early 50s I really want to be as healthy as I can going forward. Sorry about my rambles , I guess I joined to share that slow but steady lose wins the race ...

January 2025 Starters Thread 5 - Tortoises, Slow Runners, let’s lose a bit more!
Thelittlestranger · 06/03/2025 08:30

@Randomusernameforcode I gave up drinking six months last year and felt exactly the same. Where were my fun nights out? It changed sitting with my husband on a Friday night playing games when a g&t wasn't there. Girls weekends completely changed. Just because of booze. It made me realise that maybe I needed to work out what I did enjoy. I spent quite a bit of time figuring it out. I now am drinking again, but I don't need it anymore.

For example I don't really enjoy late nights out clubbing anymore. That was younger me - so drinking helped make it fun. So now I don't go. But I do enjoy 1 or two drinks at the pub with my mates, so I do that instead.

Really long way of saying - what else do you enjoy? Maybe take this time to find out...

In other news, still feeling completely unable to finish a meal on this second dose of 4.6. Not helpful when I'm out with work a lot at the moment and the conversation steers towards WLI. It is definitely the topic on everyone's lips at the moment...

Jins · 06/03/2025 08:44

I’ve always tended towards binge drinking and by that I mean nothing for months then a boozy meet up with friends, or a relaxed weekend at a festival. I’ve never had alcohol at home as a day to day thing although DH does like a beer most evenings. Yet we are both thought of as party animals with superhuman capacity for alcohol 🤷.

As a daily weigher I’ve seen a clear pattern emerge. For 3 or 4 days after my jab I’ll stay the same or gain slightly then all the weight I lose in the week goes in the last 3 days as levels drop. It’s the opposite of what I’d expect.

My mood isn’t particularly low but it does feel like there’s a long way to go. Shotsy tells me I’m 33% to goal which is great but there’s nearly 2 stone left and it feels a lot.

unicornsaremagical · 06/03/2025 08:47

i’ve also noticed a pattern, i lose the first few days after jab but then nothing. Weird how that works out. currently having a week of due to dental infection

DGonMJ · 06/03/2025 08:59

W9 D5 3.75mg

So I did get on the scales this morning. Juniper scales say 69kg exactly. Renpho say 69.45kg. I’m going to have to do an experiment with a sack of potatoes or something, to see if the discrepancy gets smaller the lighter the object is!

re: hypermobility - I’ve always known I was flexible without trying, double jointed thumbs, fingers that bend back 90 degrees, and had SPD in both pregnancies. But didn’t realise I was hypermobile till we got DS diagnosed with hypermobility syndrome - very common in autistics. Poor kid used to complain his legs hurt as a toddler and I just told him off for being lazy...all the way through to preteens. But during lockdown he completely atrophied and couldn’t walk for more than 5 mins without his ankle or foot or knee hurting. Asked my PT to start training him in the garden, he would spend 45mins releasing tight muscles rather than building strength. DH took him to his osteo who mentioned he knew a specialist in HS - we got DS a diagnosis and I cried for all the times I’d misunderstood DS’s physical pain as all in his head. The consultant explained that hypermobility means your muscles are having to work extra hard just to hold your bones together so that’s why you tire much quicker than non-hypermobile people. It explained why he walked on his toes when he learned to walk, as it would have given his ankles more stability. He said it’s likely he’s inherited it. DH has zero flexibility, so it’s all my side. Explains why PE at school was so hard, why I’m an incredibly slow runner, and why I’m better at weights than cardio. The consultant referred DS to a physio who week by week gave DS exercises to rebuild his muscles, he went from not being able to hold his arms straight out in front of his body without spasming to being able to walk up to 30mins without tiring. This was 2021. He’s 16 now and is doing heavy weights with the PT, cardio on the rower, in incredibly strong and prefers to walk the long route home from the station. I’m so proud of him. His hypermobility means he still can easily knock his hips out alignment, as do I, but we have an osteo we both go to on a regular basis who resets our hips and releases the muscles that have tightened as a result. DS has a PIP now he’s 16 and it all goes on his PT & Osteo and Vivo Barefoot shoes.

Learning about hypermobility has taught me that strength training is super important, not just to have more muscle mass to keep my metabolism high, but to hold my skeleton together!

OP posts:
meatyryvita · 06/03/2025 09:01

Week 6 Day 1
SW: 15st 10lbs
CW: 14st 5lbs
GW: 9st 10lbs

A 3.5 lb loss this week, which I'm very happy about. I went up to 5mg last week and the suppression was intense, I was worried about losing too quickly and having lots of saggy skin but it's not as dramatic as I thought and so fingers crossed I won't look like a Shar Pei by the end of this.

IBloodyLoveMyBlanket · 06/03/2025 09:18

Morning all.

Interesting to hear about you bendy folk. I'm the opposite. Grin

I've noticed an increase in night time anxiety these last couple of weeks, hoping that will pass. I'm feeling knackered from the poor sleep.

I'm trying to lose 53lb to get me to exactly 12 stone and I'm currently 20% of the way there. I'm mulling over using MJ to do the first 2 stone and see if I can do it solo from there.

Beanie567 · 06/03/2025 09:23

I had to look up hypermobility as I hadn’t heard of it before and it seems I have it - I can do the thumb to arm thing easily and bend fingers thing. I can’t bend and put my hands flat on the floor but then I have a big (but getting smaller!) tummy in the way. It’s weird how that seems to be a thing with us!

Welcome to the new posters! It’s great to hear about everyone’s experiences and I particularly like seeing the patterns of weight loss. It’s all so interesting.

Seaitoverthere · 06/03/2025 09:30

@JSGMJ welcome . I am 55 and had a hip replacement last July. Walked 3 miles yesterday which is my longest distance so far as was in a terrible state by the time I had surgery and could barely make it from the house to the car. Like you I was active before, I ran, walked and did lots of gardening. I had bad osteoarthritis in my hip and had hip dysplasia to my surprise. Very grateful for my new hip, what a difference.

My average loss is slower at 1.4lb a week and my new pen will be 7.5mg but going to take 5mg as don’t think I can tolerate higher at the moment .

@DGonMJ that has made me think about DD and actually might explain why DS can’t walk very far either.

Jjsmum2007 · 06/03/2025 10:03

RockyisMYRhino · 06/03/2025 06:31

Weigh in and jab day today and I've pretty much stayed the same again 😞 bringing me to a loss of a stone since 9 jan which I can't help but be a little disappointed by even though it's a stone I wouldn't have lost on my own as I would have got bored of a diet by now. Fingers crossed for a 'proper' loss next week!!!

This is exactly the same as me- started 9th January and lost a stone. You're right we have to remember that without MJ it would have taken months to geta stone off! I feel like we need to almost forget that we're on a weightless journey now and normalise this pattern of lower calories and moving more as for me the novelty of the losses is definitely wearing off.

Howinthehelldidthishappen · 06/03/2025 10:04

@DGonMJ Serious question, do everyone's fingers not bend back 90 degrees? Mine do, I thought it was normal.
And @Beanie567 mentioned bending down and putting hands flat on the floor. This is also something I've always been able to do. I know some people can't even touch their toes and this has always really confused me.

Jins · 06/03/2025 10:44

For those feeling low about their weekly weight loss - try comparing it to 2 weeks ago instead!

Also for those that like maths (!) and weigh daily take your average weight for the week as your weigh in. That evens out the fluctuations.

Once the water weight has gone weight loss tends to slow down so normal fluctuations seem more important than they are

MJalltheway · 06/03/2025 10:51

Feeling deflated today - in a good way. It's the first time I've actually felt a real difference, my big old belly is deflating! I feel like you do after you've just given birth and that big hard 'thing' making you uncomfortable sitting, bending etc has gone to be replaced by a soft saggy thing!

Otherwise back to normal today, diarrhoea gone thank god. I haven't noticed any mood changes since being on MJ, but it totally makes sense that we are getting fewer dopamine 'hits'.

DGonMJ · 06/03/2025 10:53

@Howinthehelldidthishappen apparently not! DH can’t bend his fingers back and thinks I’m an alien.

OP posts:
mince3point14159265 · 06/03/2025 11:25

Interesting discussions on all the bendy stuff, especially your experience with your DS @DGonMJ .

I used to be very flexible but nowadays all the joints hurt so much, so have to be very careful how I move. I've been trying to do online yoga stuff and I am beginning to find it a little easier, especially with less bulk getting in the way! I did see one doctor about my knees who said that losing 10% of body weight can reduce pain by 50%, so hopefully things will get easier as the weight comes off.