Mounjaro February to April 24 starters

[ObsidianTree]

Hi all,

Thought I would start a thread for those that started quite early on and would like a space to chat with others that started around the same time. Like the threads that are dedicated to those starting in May, June, July etc thought it would be nice to have a space for people have have been on for similar amount of time.

@ObsidianTree Sorry wanted to edit but option not there for some reason? Anyway, no she said she had titrated down but no further details on this.

I've been thinking of that poster and that thread too. I think maintenance is or is going to be hugely emotive. Many people can't afford to stay on this forever so have to believe that they can make behavioural changes to address weight gain. I think the causes of obesity are so multi factorial and it's hard to gauge whether a behavioural change will work without the glp signalling that mounjaro gives us. I'm in the cynical camp, because I'm menopausal and my metabolism is screwed without it. It's emotive though the fear of how it will pan out in maintenance. I really feel for that poster on that thread. I do think expectations need to be managed around how our bodies will respond without it. For some of us, it could just be about habits but for many of us, obesity isn't just behavioural but biological. We know how to behave after years of dieting!

I'm of the opinion that these meds fixed something in my body that was stopping me from losing before. Evidence of doing calorie deficit but not losing etc. I think I had insulin resistance and MJ has helped reverse it. Also it helps with inflammation etc so must be helping my with thyroid issues.

So I will want to stay on for as long as I can.

That is worrying. I didn't read the thread for too long.

@izzy2076
Yes, agree with everything you say. It was very uncomfortable on the thread, and attempts to give another side to the 'eat less, move more' approach were strongly rebutted, aswell as the option of long term use for those for with underlying disease (I seem to remember being called 'deluded' and accused of 'glossing over' the facts). I was very conscious that the distraught poster might be there too and she really didn't need to be feeling any worse than she already clearly was. Ah well, we all go our own way I guess, and in another year or so, we'll all know a lot more about the best way forward.

@montysma1 thanks. I will probably go up to 15mg next pen and hope it that has the full effects.

I think the short date on the 15mg must be to stop people from getting 15mg and using it to take smaller doses. As it doesn't make sense the expiry is before the 7.5mg, 10mg and 12.5mg

@KrankyKumquat yes. I strongly agree with you. I get v defensive about the trope of obesity being purely behavioural but at the same time, it's a tricky and sensitive subject to navigate as many people have to believe it's a springboard as they can't stay on them forever for various reasons. And when you are on them, you're so convinced you've cracked it when actually, it's your glp one receptors working properly for the first time in both your brain and stomach. I'm speaking for myself of course and know it may be different for others! Still, whatever way people go, there are now options if people regain so it's a lot more hopeful for all of us.

Just went to Primark and picked up a pair of size 14 skinny jeans. Thought I would aim to slim down into them. Tried them on and they fit AND feel comfortable! Woop Woop!

I re-read the first part of that thread again. So she lost most of her weight doing diet and exercise and the last stone she lost using MJ. Then came off and gained most of that stone back. I think doing MJ to lose just a stone was a bad idea as obviously the return of the hunger worked out badly for that person. She was doing well losing on her own so she didn't need the help of MJ. Also, if she only had 1st to go, sounds like her BMI wasn't over 30. Maybe this is why they don't advise people to use it if BMI isn't over 30!?!

So worrying if MJ has basically made us unable to control our own hunger anymore as we have got so used to not feeling hunger so no longer think about it. So a shock to system to want food again and have to find self control to stop.

I don't think she titrated down gradually. Think she took for 6 months to lose a st then stopped. She didn't say she titrated down? Unless she said it later in thread. I read up to page 2/3.

When reading the thread the first time I decided I didn't want to attempt to try and go it alone without MJ! So will aim to stay on for as long as I am allowed! Will probably titrate back down to 10mg and stay on that once I'm at goal weight. If I feel like I can't eat enough to maintain, then I will go down to 7.5/5. Maybe this is why these drugs are made to be on for life.

Hiiiii - I remember you! I was in the ‘get cracking now’ camp and replied to you to say don’t wait, just do it!

Glad it’s working for you x

I think people respond to these drugs different ways. Some people do well as it stops their hunger so they can eat in calorie deficit and lose weight. Other people have something broken that stops them from losing weight and MJ fixes that and helps the body function properly so they are able to lose weight. I wonder if the slow responders don't have these broken things so MJ doesn't work as effectively as it does for others.

@ObsidianTree
Well done on the jeans - I bet primark jeans are a bit skimpy too so you'd probably be a size 12 at M&S!
With nearly 3 stone lost, I've gone from a pretty roomy size 20 to a too tight size 16! Went shopping yesterday and came home empty handed and a bit gutted. I know I'm big-boned (5ft9, size 8 feet and hands like shovels) but really? Another month in tracky bottoms and baggy shorts, I reckon, then I'll be knockin 'em dead.

@ObsidianTree yes to everything you've just said. I was obese in my teens and early twenties and kept it off for years (though it was a massive struggle: constantly yo-yo-ing) in my late 30s/early forties I started taking weight training really seriously and low carb WOE. Which worked at this point.

When I hit 45 all of that stopped working. The weight gain was gradual at first and then hit I 49/HRT and slid into obesity. This all happened despite the protein, the weight lifting and eating sub 1900 cals a day (which is maintenance for my activity levels plus lifting) I don't really see how much more lifestyle change I can make bar reducing calories to 1000, which I refuse to do as I hate misery, restriction and we all know how that ends! But my point is, that the weight gain was a real epiphany for me about the causes of obesity. It was nothing behavioural: I wasn't binging, although the sugar craving was wild. The hormonal changes in my body have meant that despite doing all the right things my body was no longer playing along.

@ObsidianTree that's interesting what you say about slow responders! For me, it felt like an instant correction!

Some great losses on here! Who'd have thunk it?!

I feel like they are a bit all over the place with sizing really. A few months back I bought some size 16 shorts from Primark and they didn't fit properly until now! Also bought some size 14 trousers today as well as the jeans and they are a bit snug!

But will go to m&s next time to try on size 12 clothes for the confidence boost 😂

You're similar stats to me. I'm 5"8 and size 9 feet 🥲. It took a while to start going down dress sizes. I'm currently 12st 9lbs and now fitting into size 14s. Most of my clothes are 16+. What do you weight now? Might not be long for you! I'm hoping another St or two down and I can make size 12. That would be a dream for me!

@izzy2076 I'm the same. I've been up and down my whole adult life but only had a couple of spells in the obese bracket. But willpower always worked - did keto, noom, ww and always got down to about 10-7 and slowly regained.

Since starting menopause, from around 47-48 (I'm 50 now), I started craving sugar like I never had done before. And nothing worked. I was good during the day and then in the evenings I would eat another 1000 cals at least. And the weight crept up and up.
My hope is that if I stay on MJ long enough, the worst of the hormone imbalance will be gone and I'll stand a better chance. I am also very active, love cooking and don't often eat crap during the day.
I've also decided to try berberine. I've found these gummies on Amazon which have berberine and magnesium (which I already take) so will swap and see if it makes any difference.

😱been put on the naughty list and my post was hidden 😱😱😱

It's interesting and would be good if there was research into this. Like from that other thread, that person that lost most their weight dieting and used MJ for that last stone. It took them 6 months to lose that stone. So did it only help with hunger as there wasn't problems with their receptors etc? But that's just my theory!

Lol where? If it was this thread it's unhidden already

@ObsidianTree yeah it has come up now! Wonder why? It's normally due to some bad word being used but I don't think I said anything wrong? Oh well. They like to keep us on our toes 🤣

@ObsidianTree
Was 15st 4 (comfy size 20) to 12st 8 (too tight size 16). I've now got skinny arms, bony shoulders, and no arse but legs like a rugby player and belly looks like it needs a good iron 😂
Just shows how same height and weight means nothing when it comes to size/shape. Guess age comes into it too (57).

I believe it's the G word in your post, relating to the berberine. I think they put that on instant hide here, probably due to spam from bots offering drugs.

Yes @ObsidianTree it's so interesting to think about the science. One of the other posters on the other thread is doing well coming off meds possibly because she was a binge eater. So perhaps it does work well coming off it if the causes are behavioural rather than biological? But binge eating can be biological as well as emotional? I find it absolutely fascinating!

@CiderJabs you're basically me!! Yes. Exercise makes f... all difference once you hit 50 I've realised. 'Your muscles will consume turn you into a calorie burning furnace' they told me...yeah right. The sweet tooth thing was awful. I often felt giddy with hangriness. I wish I'd had my bloods done at the time. I had them done last week so I'm sure they are fine now but I'm pretty sure I was insulin resistant.

This has made me laugh. My belly also looks like it needs a good shake down and a strong ironing.

I don't know what the G word is!🤔😳