Yes. When Ds2 fails to have a daytime nap, I get pretty stressed about it, because he's such a klingon I find it very difficult to even do washing, he's in the laundry with me pressing buttons (his "thing").
It was better when he was smaller because I could leave him in the playpen, but by the time he was 20mo he could climb out of it .
At least he will still sit in the highchair, so I get some time to do stuff while he's having lunch, and with a bit of luck he'll doze off in the highchair too :)
DS1 was a half hour max napper when he was a small baby - drove me mad! Also a klingon. I did have to turn to the electronic nanny to get work done, else I couldn't do anything.
My biggest problem with both of them is that they both had/have breathing issues when they get really screamy - they breathe all their air out and then can't catch their breath. DS1, not so bad - used to poke him sharply in the chest to get him to catch his breath; DS2 - bloody appalling, he has several times gone on to pass out but unlike what they say, he doesn't immediately start breathing again. Fucking terrifying! He does eventually, but I don't sit around waiting, I'm giving him mild chest compressions and even mouth-to-mouth until he breathes. I can usually stop him from passing out if I catch him at the right moment and blow hard into his face - but it's not 100% effective, and if I miss it, then he's gone. Ds1 grew out of it by the time he was 3, hoping Ds2 will too (5m to go!) It's not deliberate breath-holding, they both started it at a couple of months old.
So I can't leave them to cry. Couldn't when they were tiny either because they both had inguinal hernias, and it was too risky.
Another reason why Ds2 can't go to daycare yet - I couldn't put that responsibility onto anyone else.