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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Anyone on Letrozole?

1000 replies

rubywoo24 · 25/08/2019 21:46

Hi everyone

I have been prescribed 3 cycles of Letrozole and I have just started AF after a very very long few months. So quite excited to finally getting things going!
We're currently away and I do have my medication with me but not the leaflet that came with it. So just want to double check that I am taking it correctly:

  • do I count tomorrow as CD1 as AF only started at 9.30pm today
  • is there a specific time that I have to take the tablets, I think night time is recommended?
  • do I take both tablets together?

Any other help or advice would be much appreciated!

OP posts:
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8
Carleyxo · 26/01/2020 13:44

Aww amazing did you @Sylva123 any recommendations? It's around hour and 45 from us so looking to go somewhere nice to eat too...

Oh bless you it's so hard I know how that feels though it's a bit like a big mix of emotions and feelings. Are your friends all understanding? Netflix day sounds bliss.

I really do not think that's selfish, when you get to this stage you will do ANYTHING to help and I think if you think it will be destressing then don't do it. Maybe just say you're not feeling well and rearrange for the week or two after? If you don't want to tell him why that is. But equally if you can be open just explain with the treatment you want to have a quiet month.

@TTCbabyONE Netflix with my cat would be a perfect day especially with this grey weather! I just got a cat and he's so adorable! Sounds like us three have two things in common this journey and cats 🤣

Sylva123 · 26/01/2020 14:06

@Carleyxo and @TTCbabyONE Yay the TTC Cats! Mine is a proper grumpy faced cat but I love her for it! Last night she woke me up (mid-fertility meditation on YouTube) by jumping on my chest and purring into my ear! Love them!

Yes my friends are understanding, I have the most amazing best friend. To be honest though I have massively narrowed my circle of friends because some of them have just not known what to say and I've found it exhausting trying to be smiley bubbly old me all the time, just to save their awkward feelings about it all. The group of girlies I bailed on last night are amazing though - I was honest with them that I was knackered and I'm having this fertility treatment and they are just always lovely about it. If infertility hits one in 6 people (I think?) it's bound to affect at least one of us I guess. And even though they've mostly all got kids now, it's not been smooth sailing - there's been pre-natal depression, tricky births and all that and we're always there for each other. I'm very pro being open and honest about it all cos I'm so done with tip toeing about after all these years.

Yeah you know what I think I'll just say to my dad that I need to get back to London and that I'll meet her next time. When we lost my step mum my cycle was the shortest ever because the stress was so high, I don't want to revisit anything that brings it all back up

Sylva123 · 26/01/2020 14:09

How are your friends with it all @Carleyxo?

I'm from about an hour the other side of Durdle Door and I can't actually remember any nice places to eat... Sorry! Last time I went there I took my sister for a big walk and then we went to monkey world! There must be loads and loads of cute country pubs though. It's SO beautiful. Hope it's a sunny day. X

Carleyxo · 26/01/2020 19:47

Crikey I didn't realise it's 1 in 6 that's mental. My two best friends are so so good they're just as understanding as can be and get it
Completely. They have small children each and one of my friends can relate a tiny bit as it took
Her just under a year for her second due to unknown PCOS but she knows that's nothing in comparison as it's been longer for us but she found 10 months hard enough which for me I don't think is that long.

My others are ok they're sweet but don't know what to say really.

My
Husband has an appointment in the morning to find out the results, I'm on a training course so can't go but will
Be so interested to see if it's changed @Sylva123

Carleyxo · 27/01/2020 11:17

So the SM wasn't great, a little worse than last time. She said it could just be a one off and wants him to do another before our next appointment which is in April. It's annoying how she seemed more concerned today when 9 months ago she said the results were fine!!!!! All this time if they weren't really that great why did she bother putting us on clomid straight away, why didn't she advise to do different things to increase the morphology etc then do clomid. So frustrating! I think it's hit him hard that it could be his body rather than mine etc but in a way maybe it will make him realise x

Sylva123 · 27/01/2020 13:20

Oh no @Carleyxo that is such a shame, especially after all the vitamins etc. It's just not fair is it. And to drag your body though all those chemicals etc when the issue could be elsewhere. My OH took it really badly when his results weren't great. Just like how we do when ours aren't great I guess. I'm so sorry it wasn't the news you were hoping for. Did she suggest anything to improve it? X

AfterGlow87 · 27/01/2020 16:59

Hi all! Just catching up, work been so busy. Ah sorry to see you were disappointed @Carleyxo - you never know the next one could be improved? It can vary month to month!

My friend confided in me that she’s been trying for the last 3 years and is going through a hard time at the minute - I’m the only one from our friends that know so trying to support her as much as I can - told her about me too so we both felt much better afterwards. It’s so nice to have someone to chat to 😊

Carleyxo · 27/01/2020 17:40

Yes they can @AfterGlow87 but you know they would have improved not got worse considering what we've been doing since the last one.

Not really @Sylva123 just everything we've been doing already I think? I'll speak to him more tonight but he ended up taking the day off work as felt shit. I'm not sure what else we can do?

He's eating lots of veg and salmon, not had baths in the last three months nor saunas, takes CQ10, Selenium, Lycopene, Vit C drink each day and his Wellman tablets that's been like that since at least beginning November. I'm not sure what else we can do? X

Sylva123 · 27/01/2020 18:11

Blimey @Carleyxo it's so frustrating when you're trying everything in the book and doing it all down to the last letter. It feels so unfair. When does he test again? I hope you're able to be kind to yourselves tonight. What a horrible day. Xx

Carleyxo · 27/01/2020 18:14

Our review is April beginning so he will have to test couple of weeks before then to have the results during our review. I'm going to call tomorrow because in my eyes is there any point taking letrozole for the next month if there is a high chance it won't work? I've also just found a booklet downstairs that she had given my husband about the IVF procedure :-( it's about 15 pages so I'm concerned what they spoke about. Unfortunately we both had separate prior arrangements with friends tonight so going out in the next hour which I could do without but my friend is down from up north. He has already gone out bless him @Sylva123 x

AfterGlow87 · 27/01/2020 18:36

Ah @Carleyxo sounds like he’s doing everything right. Mind yourselves tonight and have a good chat tomorrow. Might be no harm to chat to the doctor tomorrow if you can - I always find it helpful to write down any questions beforehand so you can ask everything x

Carleyxo · 27/01/2020 18:37

Do you think? I'm not sure what I would ask the doctor though? @AfterGlow87 x

AfterGlow87 · 27/01/2020 18:46

@Carleyxo I always say that to people coming through if they have any worries - saves you having to worry as you said you won’t be there for your review until April? But there’s always hope - I’ve seen samples where IVF/ICSI has even been recommended and they have gotten pregnant spontaneously

Sylva123 · 27/01/2020 20:08

@Carleyxo it's horrible when you've got to go out when really you just want to stay in and go to sleep and wake up to a fresh day!
Hopefully the IVF leaflet and conversation was one of those "just in case" things. I reckon it's definitely worth calling the clinic and saying you don't know whether it's worth doing the letrozole this month. Hopefully they'll be able to reassure you that even though the results weren't what you'd wanted there's still some hope that it can work. I hope that is the case xxx why oh why isn't there a letrozole that fixes men's sperm. :-(

Carleyxo · 27/01/2020 21:24

I hope you're right too and they've just offered it to read. I called him on the way out and asked when he would be home etc he said he was going to Tesco on the way home and I said why and he said to get new boxers I've thrown all my fitted ones away 😫😳 I wish he did this sooner though. I'll let you know what the consultant said to him when I find out later @Sylva123 x

Sylva123 · 27/01/2020 22:23

Oh bless him @Carleyxo it's probably such a reality check isn't it. You're both already doing so many positive, healthy things. It just has to go your way. Yes let me know xx

LongtermTTC · 28/01/2020 08:51

Hi all

I’m feeling a lot better now thanks, hearing that it wasn’t just me really helped. My hubby, bless him, tried so hard to jolly me along and get me out of my pit to try and cheer me up but I didn’t want “fixing”, I just needed to wallow for a few days until it passed!

7 DPO and woke up today with aching legs (like the kind that you get with AF) - not reading anything into it as have no idea of what “normal” is for me these days but just crossing fingers (and legs!) that it doesn’t herald the imminent early arrival of AF...

@Carleyxo I’m so sorry to hear that you and OH didn’t get the results you wanted - it sounds like you’ve been doing everything to the book and is all so unfair. I hope you manage to have a good chat with OH and I agree about phoning the doctor, if nothing else to put your mind at rest and not to be stressing even more about whether you should or shouldn’t take a break from the letrozole.

@Sylva123 How did your dad take it about not meeting his new girlfriend? I think you totally did the right thing in not putting extra stress on yourself. You’d only kick yourself if you got stressed and didn’t get lucky this month then you’d always wonder. It’s hard enough to cut out stress when the whole process is stressful without taking on even more and I’m sure he would understand.

@AfterGlow87 I’m glad you and your friend have opened up and can support each other through the dreadful experience. My friend has been amazing too - we were meant to be going out for lunch on Friday but I told her I couldn’t face the world (she also has a 6 month old which usually I’m fine with but wasn’t sure how I’d feel about being around babies at the time) and she was really supportive and yesterday a little parcel of thoughtful goodies arrived in the post. Love her! I’m so glad I’ve been quite open with people about our issues - it’s nothing to feel ashamed or embarrassed about and most people have been very understanding.

Sending you all best wishes this week xx

LongtermTTC · 28/01/2020 11:29

@TTCbabyONE did you get your AF yet? x

TTCbabyONE · 28/01/2020 12:01

@longtermTTC Not yet 😭 I’ve rang the clinic again this morning, still waiting for a call back. It’s so frustrating.

Taken the day off work today, spent a good chunk of yesterday feeling emotional and think it’s starting to get in top of me. Just need a down day and then will pick myself back up tomorrow.

Not been on here for couple of days, so just catching up on all your posts. Hope you’re all doing ok xx

Carleyxo · 28/01/2020 14:19

@Sylva123x so his count dropped from 25 mil to 22 - low count is classed at 20 mil. Motility down from 16% to 7% - apparently they like 30%? Morphology down from 4% - I'm so sure last time she said it was 3% but it's now down to 1% :-(

LongtermTTC · 28/01/2020 15:02

@TTCbabyONE you poor thing - I’m not surprised it’s taking its toll on you emotionally. First you’re desperate to be lucky and for your AF not to come then you’re desperately waiting for it to start. It must be a real rollercoaster. Kind of like the cruel irony of being worried about accidentally getting pregnant when you’re younger only to find out that you needn’t have worried and are now desperately hoping for the opposite (sigh)!

Hope they get back to you with something helpful soon x

TTCbabyONE · 28/01/2020 15:56

@longtermTTC I don’t know whether to laugh or cry..

Left another message for someone to call back, and the co-ordinator has gone home. And they have only just told me the lady who I want to call me isn’t even in today 🤦🏼‍♀️ So after waiting all day still haven’t got anywhere! All I wanna know is why the mess didn’t make me come on and what I can do next 😭. How are you feeling?

@Carleyxo sorry to hear that your partners results didn’t go as hoped. I don’t know anything about SA, have they recommended anything to OH? Did you call your dr today? Hopefully you will get some answers for what your next step is x

@Sylva123 how are you doing?

@AfterGlow87 that’s great that your friend has told you. Just goes to show so many people go through this and we wouldn’t even know. At least you can help and support each other. It makes such a difference finding someone to talk to who understands xx

Carleyxo · 28/01/2020 17:36

@TTCbabyONE this must be so bloody frustrating for you!!!
Nothing else advised to do as we've been doing it all already, I need to find his PH level as my reflexologist said sometimes it may suggest a infection which is easily solved with antibiotics and funnily enough I read that in the fertility plan book I'm reading. It says lots
Of doctors don't pick up on it and are just so quick to give you medication rather than resolve the issue.
Clomid never ever would of
Worked with his numbers and it's extremely unlikely Letrozole won't.

The consultant said to just take the month we have left but I really think that's the end of the road for us after that x

Sylva123 · 28/01/2020 21:16

Oh @Carleyxo I'm so sorry. I'll never understand all this - how the results can change so quickly even when people throw so much energy at it. You've been doing all the right things. It is simply not fair. It goes against everything I thought I knew about the world - that if we just did our best and worked hard enough at it, it would happen. The unfairness of it really stings. How are you both feeling today?

The PH level sounds interesting. How do you go about finding that? And what does that mean for you now - is it IVF or are you going to pause and just think about your options for a bit? It's a huge amount to take in for you both. It's understandable if you just don't know. X

Sylva123 · 28/01/2020 21:20

@TTCbabyONE hope you're feeling a bit better this evening. I think I've replaced those emotional days with just pure anger at it all. I'm so angry that we're all going through this!

Sending love to all of you.
CD 18 today. Wish me luck that my cycle is longer than 21 days this month 🤞🤞🤞🤞

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