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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Ivf anyone starting stimms next week?

523 replies

naty1 · 29/01/2014 21:35

Im starting stimns next week for icsi(dependent on blood test)?
Anyone at the same time want to join.

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suzylee73 · 15/02/2014 22:53

Yes another blood test on Friday then hopefully I can start the gonal f, it's taking up shed loads of space in my fridge right now!
I'm not sure why it's taking so long but maybe it's because I'm an old bird at 40? On the grand scale of things I guess another week is nothing Smile
I feel like your so close to the end now naty, roll on ec, hope it's really soon

Shellster52 · 16/02/2014 00:09

Thank you SO MUCH for your kind words suzylee. Hubby doesn't like to talk about it so it means so much to get some support on here. I started a new IVF thread for anyone starting IVF in the next week or two as naty will be outta here once she gets her BFP in two weeks (thinking positive for you)! I am 36 but my AMH indicates my ovaries are much older and I don't get many eggs so it might be nice to chat together.

Can someone explain this down reg thing to me? Do you start the sniffing at the start of your cycle? And then it stops you from getting another period and you just start stims when bloods show all your hormone levels are low?

naty1 · 16/02/2014 12:51

Cd 21 Start the pill for 7 days then a couple of days in the down reg (nasal spray) for about 2 weeks during which u get a period.
Then a blood test. If all ok stimms the next day. You continue the spray until collection (or around then , havent got that page yet)

I now have 8 larger follicles and lots of smaller ones.
They will call back with results of blood test later today.
She seemed to think tues for EC but i was trying to point out i could do with some of smaller ones growing as only 2 fertilised last time.
Seems like they would be happy with the 8 follicles but im not as not all will have eggs in and then so few may fertilise.
It will just depend on how cautious they want to be.
Its a bit frustrating when the potential was there for more.
8 eggs would be great with even 50% fertilisation. (But i had 20% last time)

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naty1 · 16/02/2014 15:34

Well its on for tues so looks like a max of 8 eggs.
Though i take todays dose 150 menupor so more could join and grow.
Also trigger tonight.

I do always seem to respond to meds strongly though

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naty1 · 16/02/2014 15:36

I kept my menopur in fridge last time as it was unusually warm for sept and worried it would go over 25 degrees.

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naty1 · 16/02/2014 15:37

I kept my menopur in fridge last time as it was unusually warm for sept and worried it would go over 25 degrees.

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suzylee73 · 16/02/2014 18:53

So tues should be egg collection and hubby needs to do his thing? It must be nerve wracking! I'm ever so slightly worried hubby's sperm won't be up to the job and this will have been for nothing, is that a common worry do you think?

suzylee73 · 16/02/2014 18:57

Shellster, I'm on the long protocol so my down reg is a little different. I am on buserelin which I have to inject everyday. I will have down regard for 3 weeks by the time I start stimming, still had a normal af which I pray will be my last for around 9 months Grin
Tbh I don't bother myself with the technical stuff and have no idea what my hormone levels are or anything I worry less this way Smile

naty1 · 16/02/2014 20:14

Yes tues EC
Though the notice for his abstaining was a bit short today 8:30am is 48 hrs so when we were told 3pm already less than the 2 days minimum.

Luckily we didnt need to worry about that as it falls within the 2-4 days before we have just been told we need.
We have some sperm frozen i presume they will defrost it just in case.
Suzy i shouldnt think there would be a sperm problem if it is usually analysed fine.
(We have a really bad SA)

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Shellster52 · 16/02/2014 21:04

Thanks for the info on down reg Nat. So after you stop the pill you get a period, and then basically you just start stimming when your body has shut down, regardless of it is in the middle of a cycle. When was your AF during the down regging Suzylee? Sorry for all the questions, just trying to understand it all! I wish I could be like you suzy and leave the technical stuff to the experts to stop me worrying but my mind just has to know everything. Either way I am very happy with the protocol my dr has set in place for my next IVF so hopefully it stops me worrying.

Oh Naty, I can almost feel your nerves and the anxiousness in wanting more eggs in the hope that you get a few fertilised. Were any of the smaller follicles at least 10-12mm so that they might be mature by Tue. Just have to pray for higher fertilisation rate this time. The anxious wait begins. I will be thinking of you.

naty1 · 16/02/2014 21:27

Yes stim when you have down reg. 1st stim day is cd1 (despite period before then)
I had been more relaxed this time (but at least i know vaguely how many this time so not overconfident like last time)
I dont think they measured the smaller ones, she was so focused on the larger ones as maybe 8 would be what they aim for.
Last time i had 2(3) immature eggs .
But i suppose this time they may collect some of the others as immature ones
(When we had only 1 fertilised at a point they injected an egg that had matured over the day but that didnt fertilise either)
Maybe theyll all fertilise this time

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Shellster52 · 17/02/2014 03:49

A few more days and you will know all. But I am sure those few days are going to take forever.

I was preparing to do IVF next round but last cycle was only 21 days which is unusual meaning I probably didn't ovulate so this cycle I have done OPKs and today is CD 14 but still no LH surge so now I am worried that my body is not going through the normal process of ovulating and recruiting more antral follicles ready for next cycle and IVF is going to be a waste of money and emotions.

So here I am telling you just a few more days when I am anxiously waiting every need to pee so I can do an OPK!

suzylee73 · 18/02/2014 07:50

I can't believe it's Tuesday already! Will be thinking of you today naty Smile

naty1 · 18/02/2014 13:07

All done.
9 collected though sounded like lots could be immature.
They wont call till thurs, really long wait.

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naty1 · 18/02/2014 16:41

They called back only 4 were mature and have been injected.
:(
Oh dear not very happy with clinic. They should have let me go on to at least monday with stimms.
I asked if any matured today whether they will inject those? And they said no unless there were very few fertilised.
So have decided to call tomorrow and ask for and matured ones to be injected.
(They dont want them out of synch)
I cant see i will have more than 1 fertilised... Could well be 0 due to mfi issues only 28% fertilised last time.
Im sure i must be abke to request that after all we are paying.

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suzylee73 · 18/02/2014 20:25

Hopefully it's not totally bad news, I mean it only takes one to do the job right? Please don't be disheartened Naty it's not over yet hun

suzylee73 · 18/02/2014 20:28

How many days did you stim for?

naty1 · 18/02/2014 21:16

12 days.
I have been reading though it takes 5-6 hours to mature the eggs op at 1030-11am but they called at 4pm so only just enough time hardly surprising they are immature.
I was last patient too...
But odd as at 4pm they have another hour to let them mature.
I guess maybe skill of surgeon and luck plays a part.
It would have been nice to have some frosties but at mo any at all would be nice

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Shellster52 · 19/02/2014 00:54

Oh Naty. My heart goes out to you. Having been there and done that, I can recall the pain all too clearly. I always felt jealous of PCOS sufferers thinking that you over respond to IVF and get so many more eggs than my measly 4-6 with my disgustingly low AMH. But you only got 4.

I can imagine how frustrated you must be considering you initially said you wanted to stim longer. I guess if you had of, then these 4 mature ones would have been over mature. I am just so anxious for you and waiting to hear what updates you get.

naty1 · 19/02/2014 10:03

I have left a message with clinic hope to get call back to ask them to inject the immature ones.
I cant help but think they have gone a bit wrong

What seems wrong is that even if they did trigger me too soon or any other error they make you have to pay anyway.

I have read pcos people often have more immature ones.
I think if i was to do this again (which i wont) i would want to be able to get many more eggs.
Though i always felt with pcos a cycle right after xmas would be a bad idea. If i hadnt been so impatient i woukd have waited a few months.

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naty1 · 19/02/2014 17:33

So far 2 are fertilised plus 1 abnormally.
But it is only day 1 have to wait until tommorrow to see how they are doing

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suzylee73 · 19/02/2014 21:16

It must be doubling annoying when your paying. I'm getting my first round on the NHS but will be a paying customer if it doesn't work. I'm sure they are doing what they thinks best, they want success too so try not to stress. No embryo wants a stressed out womb Smile

Shellster52 · 19/02/2014 23:17

Don't worry Nat. It's completely normal to be stressed now and I am sure every woman going through IVF is. Once you get the good news that your future baby is growing nicely and safely returned inside you, you will feel better. But I have been where you are and know that every minute seems like hours when you are waiting for an update.

What day transfer does your clinic do? What day transfer did you have with your first IVF?

Shellster52 · 20/02/2014 04:54

Nat, just found this info on the internet and thought it might reassure you that your clinic did the best thing in collecting the eggs that were mature first rather than allowing them to over mature to collect more of the second batch of smaller follicles:

If you had 1 or 2 follicles that developed far ahead of the rest and had to be sacrificed to let the others catch up (often a bad idea as the fastest follicles may contain the best quality eggs of the whole batch), you may do better on a long protocol rather than short.

www.fertilityfriends.co.uk/forum/index.php?topic=283000.0

naty1 · 20/02/2014 09:04

I didnt really pay attention to the sizes as they were measured. It looked like there were about 4 per ovary of a similar size
It sounds like you can get immature ones that stick to the follicle or the message from the trigger to those doesnt work.

It looks like from yesterday that the fertilisation % was a lot higher this time

What we did was
Me
Both times
Pregnacare conception
Metformin (for pcos though the dose was higher this time)
Cut down chocolate and cakes eat brown bread
This time
Coenzymeq10
Levothyroxine (for hypothyroidism)
Sometimes omega3
Brazil nuts
Milk
Less stress im off work with the baby
Him
Both times
Pregnacare conception for men
This time
(Had his teeth sorted, he did have gum disease)

I think the lining is much thicker this time (it looks like im pregnant) but im not sure if thats the brazil nuts or milk? I think it may be too thick as its uncomfortable.
Of course i dont know if some of the extra things this time caused some of the eggs to be immature they did grow quicker this time

We did day 3 transfer last time it would be today or tomorrow this time

We time if they will only allow 1 we may ask them to grow them on a day to tommorrow to see if there is a difference between them (also no pt freezing if its not looking good by then )
I wonder if they would grow the other 1 to blast

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