Assisted conception after recurrent miscarriage part 5

[Mel3062]

Hope this is right ladies ...

No NHS test just motility and mobility and count. I would recommend sticking with prof quenby and if her plan doesn't work then you can try someone else. I only went to dr Gorgy after a year on dr s plan and the 2 chromosonally perfect IVF losses with full immunes (Not hydroxy). As it happened my nk count was normal when I tested with him but it fluctuates as you know. Stick with prof quenby for now and give her a chance. Dr G can be if you don't get anywhere with prof Q. It is a frightening time. Zita west and dr Nudwuke is another one that some people on here are seeing and to be honest you could do the rounds with all of them and we still can't control the natural chromosonal miscarriages that we may have in there ! Keep us updated on how you get on.

How are sue, pebbles and scooter doing ?x

Thanks duggs your right. Don't think hubby will be willing to see anyone else after this :( I guess I was right to get nk retested even though uterus is ok x

Hi Duggs am doing ok but just lurking at the mo. Miscarriage has defo finished and just waiting for af to arrive but looks like it will take its time. Was hoping to use the frozen embryo before Xmas but think it will be to close and can't face it all and another m/c over Xmas. Having some days when feel really down and stupid things like looking through Boots Xmas catalogue and seeing newborn my first Xmas things bringing tears to my eyes! Think deep down I am scared as facing the end of the road as can't pay out for ivf over and over. Is v frustrating to not get pregnant naturally and then miscarry when I do!!

How are you going Duggs and have you had af since m/c? What is your plan if action next?

Mel I hope you get some answers and find the treatment that works for you, good luck!

Interesting talk about supplements I have pretty much stopped the aspirin now and take multi but with omega, vit D, methylfolate, hydroxy and metformin which seems a lot!

How are you feeling Ari? Hope things see going in the right direction for your dd.

Know exactly how you feel pebbles, it still hurts a lot when you walk through somewhere like Sains and see all these cute baby Xmas outfits. And know what you mean about not being able to pay for IVF over and over. Do NewLife at least know what the problem was this time, do you know? Big hugs for you, try to look forward and hope that the New Year will bring a whole new perspective for us all!

I stopped aspirin a while ago, naughty me since I'm supposed to take it for MTHFR anyway, but enough is enough, I still rattle anyway!

AFM, well, sad that I'm still not pregnant and can't even begin looking at doing another cycle until DD is well. Feeling old, and that time may have just passed me by, I know OH thinks he's too old for a baby. DD has good days and bad, but her HSP is still very firmly in place. I know in my rational mind that it's much too early to have gone, she's only had it for 5 weeks and apparently the 'average' if it goes without complications is 3 months. But it's hard, naturally hope rises when she has days that her rash disappears, but then crashes when it all comes back. Half-term has proved that resting helps enormously, but she has to go back to school next week, so I start worrying all over again.

Anyway, enough of me, I'll go back to lurking and rooting for you all!

Ari can I be so bold to ask if DD does recover by early next year for example (which sounds possible from what you've said?) would you try donor egg at serum as next step? What did penny recommend?

Oh and pebbles. Yes wish I was pregnant safely. Not looking forward to Christmas again. I'm seeing dr S on Saturday so I can get some more hydroxy and pred. This last mc was chromosonal but I will ask him if my 2 trisomies at 34 and 36 might be because of the nk cells damaging my eggs? Will also see what he has to say here in autumn 2013. I will then hopefully do an IVF round before Christmas. If that fails or I have another mc then we will have to pay for a last one with my own eggs in the new year. If that fails too or mc then I will seriously consider DE at serum. Will be asking ari about her experiences there. Pebbles could you possibly think about that too ?

Forgot to answer pebbles my AF came back 5 weeks 2 days after my D&C. It always has with all 4 of my D&C's (lucky me). I did take pred this cycle and am on hydroxy. Actually 10dpo is tomorrow but I don't think I'm pregnant that would be just too easy. I will have to go and buy a test though so I can stop the pred.

It's such an unfair tough struggle for everyone and I'm sorry if I seem insensitive at times I am thankful that I haven't required ivf as yet x

Don't be silly mel! This wouldn't be wished on our worst enemies we all know that. I at least have the option of IVF but i have gotten pregnant 5 times naturally (fat lot of use it has done me) so I can't say I am much different!

Had a consultation with Mr Gafar and he couldn't really say what might have caused but could be a good chance it was chromosomal considering all the immune drugs I was on. Miscarried naturally so no testing.

I know what you mean about feeling old, was talking to a young temp at work who is 18 and she said her mum was 43 and thinking god I am old enough to be her mum and would kill for a grown up daughter....

Anyway I hope your time comes soon Ari and maybe tomorrow will be the year.

Duggs hope you get to start the ivf soon and even better that you are already pregnant!

If this last frozen one doesn't work then I think de at Serum will be our next option, they sound great from everything Ari had said. I just don't think we can justify another 9-10k round of ivf for the same thing to happen.

Mel if you can get pregnant naturally or not you are still having a crap time with multiple miscarriage. Please don't feel bad although will admit I am a little jealous of you ladies who get pregnant naturally, would love to experience it just once!

Anyway happy Halloween everyone, I am off out for a few glasses of

duggs My last cycle was DE at Serum - and I cannot recommend them, and Penny, highly enough. The fact that not only do they tailor your treatment to you as an individual, rather than a standard protocol, but also they seem to genuinely care about you. I honestly couldn't recommend them more. Assuming I can do another cycle it will have to be DD this time, as my immune system is just too damn aggressive and will always kill off anything with OH's DNA in it. :(

mel You're in no way being insensitive .. as pebbles says you're going through just as cr@ppy a time as any of us. It's hell that any of us have to repeatedly go through what we do, yet we still pick ourselves up each and every time and try again.

Thanks ladies. My rmc consultant has had the results from prof quenby ( she suggested I see her) and she's told me to continue 5 mg folic acid and thyroxine as they have dif role and don't affect endometrium. She's told me to try whilst it all looks good!

Thanks Ari! That is very good and comforting to know. I know we will take this serum route if things don't work out with us with the next 2 IVF attempts. Next stop is app 21 nov and hopefully I can start the end of this month... How is everyone doing ?

Good luck Mel!

Hooray af arrived today! Means I can now plan for treatment, would be nice to start straight away. Need scratch at end of month and would start treatment on next af but think it will all fall to close to Xmas and I onus my Nhs clinics d

Don't let you cycle at that time so will need to check with NLC.

Good luck pebbles :)
Please can anyone help with my results? Hubby's says scanty white blood cells, no growth or organisms seen is that good??mycoplasma and ureaplasm a negative.
As for me:50.1: 20.7
25.1: 13.4
12.5:1 : 10.1
Ivig 12.5 mg 50.1:18.4
Ivig 12.5 25:1 : 11.3
Intralipid 1.5 50.1: 16:2
Intralipid 1:5 25:1 : 11.2
Cd3 : 76:5
Cd19: 2.5
Cd56 : 20 h ( in red)
Cd19+ cd5 7.7
Tnf: 28.2
Ifn cd 3 and 4: 7:7
Lad results :
Flowcytometry negetive
T cells igm 2.1
B cells igm 7:0
T cells igg 3.4
B cells igg 9:0
Any clue?? I assume I have to wait still for hubby's lad result x

mel You won't get LAD results for your DH, LAD is simply about your body's reaction to his DNA. The problem with LAD is apparently that if you haven't been recently pregnant to past the first trimester, it's supposed to be low, although some people like Dr G always want LIT treatment whenever they see low LAD. I had even lower LAD results than you!

Can I suggest that you post your results on FF, I'd suggest the 'Immune Issuess & Investigations' board, so that you can get the benefit of the fabulous Agate's advice? She knows so very much about these results, what they all mean, what likely treatment would be etc; I for one would only be guessing if I tried to work them out!

pebbles Excellent news that your AF has turned up, best of luck for your next try!

/waves to everyone

mel forgot to ask, did you get DQa tested? And doh, of course I typed the wrong thing above, I was thinking of DQa when I typed that! It doesn't of course test your body's reaction to your DH's DNA, it tests for antibody reactions to proteins from DH.

mel If it helps you at all, a lady posted yesterday with similar-ish LAD results to yours (think hers were a tiny bit lower but not enough to be significantly different), and Agate's reply to her was this:

unless you have had several miscarriages/been pregnant past first trimester recently, its not possible to know if your low LAD is normal. It PROBABLY is and it PROBABLY doesn't need treating with LIT

That's just for the LAD bit - you still need someone knowledgable to comment on the rest of it :)

Thanks ari I can't even compare them to mr s results!

No, unfortunately his are in a completely different format :(

Ari - quick question about donor eggs at serum! Did I read correctly about a cycle where they stimulate you and an Egg donor and then they can put the best embryos from both cycles back? Or have I got that wrong? X

But then how would you know which it was if you got a BFP? I read on the surrogacy website that in the UK where you have male gay couples, you're not allowed to use a mixture of both sperm on a given cycle to try to inseminate the donor egg, and wouldn't that be the same kind of thing?

Perhaps it was that that both you and the ED were cycled and the best embryos selected? Can't remember ? Was in Greece so different laws I presume ?!