I tried smoking around 11, I took one from my mums packet to be rebellious, it was disgusting.
I first got drunk about 12/13, that was pretty standard among my friends, spirits then alcopops. Other friends got into smoking cigarettes, I followed suit. We would ask people to buy white lightening and sit in the park in school holidays.
Around 15 I tried ecstasy, nothing happened until 5am then I was flooded with it. I had to go to work and I remember dancing in my bedroom when I got home.
At college it was LSD, mushroom, ecstasy and speed (god awful stuff) at the weekends at house parties and clubbing. Most of my friends smoked weed and I did socially but never on my own and I rarely bought it.
By the time I went to University I was a bit over it to be honest but did do a bit of mdma and coke.
After that I had a lost few months where I did liquid acid and ketamine. Unsurprisingly I ended up on antidepressants for a short while.
There was then another short period in mid 20s where I took quite a bit of mdma.
After that it was no longer a lifestyle thing. I very ocasionally did coke or mdma if people had it. I gave up smoking.
I no longer do drugs and probably have one drink a month, if that.
Purely from a health perspective I think you have to stop drugs by mid 30s and aim for a healthy lifestyle.