MHRA may change advice for young people receiving AZ vaccine

[IloveSooty424]

I just saw this news story on Channel 4 news tonight.

www.channel4.com/news/uk-medicines-regulator-considers-issuing-new-advice-over-oxford-astrazeneca-jab

It seems the MHRA may follow other European countries and Canada and advise that younger people should not receive the AZ vaccine. It seems the decision will be made imminently in the coming days.

I’m due to book my vaccine this week and don’t know whether to wait and see how this plays out. I’m 42. I’m also concerned that if younger people will only be offered the Pfizer vaccine it will slow down the vaccine programme substantially.

Any thoughts?

What happens to those who have had one already....what will happen for their second? Dd has had her first of AZ already.

Must admit if I was in my 20s or 30s and due to be having it I’m not sure I’d want to now until they clarify this either way.

Although re reading it the article doesn’t say the mhra are reconsidering it....says they’re being urged to reconsider it. But who by? Anti vaxxers or people who know what they’re talking about?

By people who know what they are talking about in my view.

There are other vaccines nearing readiness for distribution so any delay should be temporary, shouldn't it?

What classes as younger? I had to work really hard to persuade DM to get her jab because of all the shite she reads on Facebook that scared her. She's really not going to want to get her second now .

@CovidCorvid

What happens to those who have had one already....what will happen for their second? Dd has had her first of AZ already.

That’s something I’d love to have an answer to as well. My son is 20 and CEV, he’s due his second one this month.

In 44 and had one, I hope to god I get the second

Group 6

@Beebityboo

What classes as younger? I had to work really hard to persuade DM to get her jab because of all the shite she reads on Facebook that scared her. She's really not going to want to get her second now .

In Europe it’s either below 60 or 55. It applies to both men and women even though women are the ones most at risk. I’m worried about my sister who is 27 and received her first AZ jab a month ago. Will she be able to have her next one?

Great. Mum is 59. She's really not going to want to get the second, and then what happens? What a bloody mess!

@CovidCorvid

Although re reading it the article doesn’t say the mhra are reconsidering it....says they’re being urged to reconsider it. But who by? Anti vaxxers or people who know what they’re talking about?

That’s what I thought. Doesn’t seem like mhra will make an statement and it’s more media trying to give some information ... which might not be accurate but might worry some people.

Also by the time 20s people are vaccinated there might be j& j or Novavax so it might not be pfizer what they’d be provided (and if it’s then those that need their second dose would be most likely prioritised )

@Beebityboo

What classes as younger? I had to work really hard to persuade DM to get her jab because of all the shite she reads on Facebook that scared her. She's really not going to want to get her second now .

Below 30s I’ve read

I’m mid 30s and 10 days post vaccine, very anxious.

I’m also gutted that despite cheerfully rolling up my sleeve when invited im now in a position where (assuming I’m ok from the first one as I’m not out of the danger period yet!) I either take a second vaccine shot that is either no longer advised for the age group or pretty close. Or I mix and match vaccines in a fairly untested way. So probably I’ll do neither and be less protected and I so wanted this vaccine. 😭

@Boringlynormal

I’m mid 30s and 10 days post vaccine, very anxious.

I’m also gutted that despite cheerfully rolling up my sleeve when invited im now in a position where (assuming I’m ok from the first one as I’m not out of the danger period yet!) I either take a second vaccine shot that is either no longer advised for the age group or pretty close. Or I mix and match vaccines in a fairly untested way. So probably I’ll do neither and be less protected and I so wanted this vaccine. 😭

O think in your position I’d wait and see what mhra says. If tbey don’t allow the vaccine then they’ll have to come up with a plan so I’d see what is said. Fairly sure that they’d want you to take a second vaccine. Today In the press conference they were saying if they call you for your second vaccine have it ...

So how long are you at risk for after? Dd is about 3 weeks post injection?

The last summary on the MHRA website on 24th March says they’ve had 22 reports out of 15.8 million doses given. I’m not sure how many since but given the risk of covid I’m not sure it’s significant enough, certainly for the age groups and risk factors who have already been done. Especially when you take into account background incidence and risk of clotting associated with covid infection. Will be interesting to see what their next press release says. I wonder if there are reports with the Russian vaccine which is very similar to AZ

This information is coming from a statement made by Neil Ferguson on the radio today. He said people under 30 shouldn’t receive the AZ vaccine. The MHRA is expected to make a decision on it as early as tomorrow.

I’d go with what the MHRA say rather than Neil Ferguson’s personal opinion given his previous track record. People in their 20s without co-morbidity are at such low risk from covid that it does obviously affect the risk:benefit .

@BungleandGeorge

I’d go with what the MHRA say rather than Neil Ferguson’s personal opinion given his previous track record. People in their 20s without co-morbidity are at such low risk from covid that it does obviously affect the risk:benefit .

This. Problem is if mhra doesn’t ban it people will carry on thinking below 30s is not safe and will refuse it

So firstly it says they are being urged to consider, not that they will and it doesnt say who is urging

Secondly it seems if it is going to affect you it’s after the first jab
Thirdly, you do realise you get the same clots from Pfizer? It’s just that for some reason it’s not being so well published in the EU ( which is where the scaremongering started)

Fourthly it’s 30 people out of 17m who have been vaccinated, and all regulators are saying it’s safe at the moment. The clot itself is a very rare one, so much so that not much is available by way of stats for normal times. So there is no way of knowing if this is more than normal, or normal but just highlighted now

The Sun is reporting younger as under 30s

Do you have a link to the info that you get the same clots from Pfizer?

It just doesn't make sense to me, considering the stats. There have been 17m vaccines given and the incidence of clots is in low double figures. I'm not a statistician but surely the has to show that on balance it's safe for the vast vast majority who take it?

Hmmmm, I'm 37, and have had my first AZ vaccine a month ago. Wonder what will happen?

If you gave 15 million people a placebo and followed them up you’d get all sorts reported. Even young people drop dead from heart problems, blood clots, aneurisms etc. When something happens rarely it’s very difficult to make the call as to whether it’s potentially due to the vaccine. They don’t know basically. There’s no consensus between countries either. I had heard that Pfizer also had this reported but the MHRA website seems to say it hasn’t been reported. Although not many younger people have had Pfizer in this country so that could bias the results. They may have had reports in countries such as Israel were the Pfizer has been given to younger patients

It would be difficult if they draw the line at 30 - doesn't exactly reassure the rest of the 40s and 30s age groups, especially when other countries have stopped giving it to people under 60/65.

From what I understand, there have been some clots reported after Pfizer but they are the more common type of a clot you could expect to see anyway if you followed a large group of people over a given time period. The clots after AZ have been in the brain (CSVT) and also associated with low platelets which is unusual as that would usually cause bleeding, not clotting. Scandinavian countries where numbers of vaccinations given are lower than here in the UK have also noticed these cases, much more so than they would normally expect to see.