Immune/NK issues - aka Pred Thread no.20!

[harrietm87]

Hi all, thought I'd get the ball rolling on the new thread.

Welcome all with immune/natural killer cell issues.

It's been a while since a new thread so thought it might be helpful if we all added our stats:

I'm harriet, age 30, TTC#1.
3 mcs (2 at 5 weeks, 1 mmc at 9 weeks).
Hypothyroid and high NK cells.
Cycle 2 on pred!

Oh my goodness Justla so exciting about your scan! I'm certain it'll be great results all around. Your baby bump fantasies are around the corner :-)

Drttc great news re ur scan!!! Fingers crossed. Totally can see why ur drug free, I've often wondered the same if I ever tried again. Let Me try get one safely here first though!

Seeking when was ur next one ?

I'm 29.5 weeks now and still being sick! It's utterly hideous. It's only a few times a week but it's still gross. I had 10 days sick free at 22 weeks and that was it! I just chant "it's not forever" but I don't know how those women with hyperemsis gravidum cope!

Drttc, you poor thing. One worry exchanged for another. Seems like it came on super suddenly though, does seem to suggest a bug.

JustLa, still extremely low risk though. And great you can get the answer from the Harmony scan as the amnio is a scary prospect for women with our history.

Harriet, how are you getting on?

Haven't felt sick today or yesterday really and now I've got browny/pink cm so I think I'm out. Will call to try and get to EPU ahead of my appointment with MrS.
I felt like this was going to happen, so I feel weirdly ok about it. Obviously I'm sad but I'm not shocked.

Oh Seeking, the dreaded discoloured cm. It's so awful seeing it. We all know it could be fine but we've all been burned by it too and simply can't relax once it's there. Thinking of you and really hoping it's fine...xx Didn't you have this earlier in your pregnancy too?

Seeking :(
Don't give up yet, mr s knows his stuff and he sounded very reassuring when he saw u. Keeping things crossed xxx

Just back from very full on weekend away. I was so exhausted and had to try so hard to look like I was enjoying myself!

seeking please please don't say that you're out. I have just had yet more brown cm (it stopped about a week ago) and I've been telling myself it's fine and normal, which is what mr s's clinic said. Unless it turns into red bleeding there is no reason to worry. Hope you can get an NHS scan soon - have you heard back from them?

drttc I'm so delighted for you - what excellent news! It's so great that you trusted your instincts - don't think I'd have been brave enough for that. Hope you're feeling better now. Did you have morning sickness with your ds even through the pred? Other than extreme tiredness and hunger and bigger boobs I still haven't had any symptoms- no sickness or sore boobs. 5+4 today I think.

😰😰😰seeking.... I'm not counting you as out yet - let's see what the scan shows... hope you got an appointment or can get one first thing tomorrow 🙏🙏🙏❤️

Urg harriet early pregnant and at a raucous bday weekend - well done!

Oh Seeking xx I know you've not been feeling this pregnancy will be a lucky one but nothing definite has happened yet. Lots of women have bleeds and some big bleeds and are fine.
I know we are a pretty high risk little bunch, but it could and should still be totally fine for you. Hope you can call early pregnancy unit at local hospital or your gp first thing tomorrow and get a scan asap.
Sending lots of support your way ❤️

Trying, good to hear from you but sorry you're feeling sickly. Are you due end of October?

Harriet, glad you made it through! Sorry to hear you're having more concerns but you seem to be doing well not worrying too much, it sounds like just one of those random things. I had some brown at your stage, it went away and mr S couldn't see a bleed site.

Poppy you're right, I wouldn't want to take the risk after going through so much to make a success of this, so glad I can pay for the test- even if the price means it's beans on toast for tea for the next month ..

Xxx

Thanks ladies, I have read hundreds of positive stories about people in my position but I have a gut instinct. I knew it with the one before Tallulah too and I kind of know it now. For me brown cm has never ended well. I hope to god I'm wrong but I don't think I am. Will call midwife or go tomorrow to try and get a scan. I must sound like the most negative person in the world, which it really not, I'm just trying not to get my hopes up. DH is pretty devastated

Good luck with your scan Just, I'm sure all will be well.

Really hope you're not at the start of awful sickness drttc, go to the gp of it continues.

Lovely to hear from you trying. Sorry you're not feeling great with sickness.but you're getting closer to the end, soon that precious baby will be with you

Seeking really hope you get on OK today, I can imagine how unsettled you must be feeling. Hugs x

I can't remember who else is on Thyroxine here, but as I take it first thing in the morning, I wondered about whether the Omeprazole I'm now taking (to limit the stomach disturbances caused by Pred) could affect the absorption of the Thyroxine? Had a quick Google and noticed a couple of remarks that's it can adversely affect its performance. I currently take Thyroxine @ 7.30am, Omeprazole @ 8am, then the Pred after breakfast between 8.30-9.30am. Anyone on the same meds have any thoughts? Wondering whether I leave bigger gaps in between the meds or just drop the Omeprazole altogether and accept the stomach issues.

seeking please let us know how you get on. I'll be thinking of you today.

tee I take my thyroxine last thing before bed. Calcium can also affect the absorption of thyroxine and I usually have milk and/or yoghurt at breakfast so was advised years ago to take it at night instead and haven't had any problems. I'd try that rather than omitting the omeprazole.

That's interesting Harriet, thanks. One thought on that though is that I take my vast array of supplements after dinner which would certainly include calcium. I don't eat dinner until about 8pm so don't feel like I'd have an empty stomach by the time I go to bed @ 11ish 🤔 Or would dinner be processed (by the stomach at least) by then I wonder...

Oh Seeking I really hope it turns out positively today. I agree that the actual symptom in itself doesn't sound worrying, so praying your feeling is wrong this time xx

Hi tee sorry should have said - I take my vitamins (pregnacare max and vitamin D) after lunch to avoid that issue. My routine is cyclogest 30mins before I get out of bed, then omeprazole before breakfast, pred after breakfast, vits after lunch and thyroxine and more cyclogest before bed - such a faff!!!

Thinking of you today Seeking. Hopefully the cm is just your womb doing its job and getting rid of old stuff and that your instinct is actually just some perfectly natural worrying xxx

I agree with the meds being a faff! After I do my heparin injection, I run up and down the stairs with the leg I just stabbed to circulate the liquid, or it burns lol. I then have to keep moving for a bit and look like a total nut job 😂
Omez and pred at breakkie, vitamins and aspirin after dinner, cyclo before bed (have to have one pee, get into bed, get out for another then go for it lol)
I can barely be bothered to deal with my slow digestive system and the severe acne outbreak on my chest! But... it will all be worth it if this works out 😊

Good luck sweetie seeking 🙏

harriet how's the spotting?

Just jeeeez what a faff indeed!! You poor little thing!!!

Drttc how you feeling Hun?

Thanks luna it's still there. GROSS POST alert!

Im only getting it when I wipe and it's weird - it's not liquid at all - really thick and creamy CM but just brown rather than white. I've never had it before. Also having some light cramps this morning and have had a bad case of the runs! So who knows what's going on. I'm trying not to worry. Scan is 1 week today.

Hey Luna thanks for asking- I'm still feeling fragile but much better than yesterday. Have stopped throwing up and can now hold down water and bland food. Was definitely a horrible stomach bug! Now I have that nauseating feeling hanging about all day. Worried about the dehydration and illness affecting the little bean :-( But want to recover more before going for another scan. Might try for an EPU scan in the next week if I can.

Harriet those symptoms don't sound worrisome. Hope you've not caught a bug like I have- I swear everyone we know has had something in the last month or so and I foolishly thought I'd dodged it! So the scan is next Monday? Not long now!

I'm assuming CM is discharge basically harriet? I'm crap with learning the code letters!! Will you call the clinic and see what they say?

Drttc, glad you're feeling better, and that it most prob a bug! Not sure if your little one goes to nursery, but I've had the norovirus about 5 times in 1.5 years! Not great!! Goo idea to stay away from people until you're completely better!

seeking.... any news?

Yes luna cm = cervical mucus aka discharge.

Just had some pinkish CM as well for the first time and terrified I'm out now. Ffs I'm so sick of this. My natural mcs started with red bleeding like a period but were much earlier than this.

I'm in work and really can't get out to the epu this afternoon. I will try to go tomorrow if it continues/gets worse.

Hope you are ok seeking

harriet I'm really sorry this is happening... i really don't know what to say as it's could just as easily be nothing bad - wish we could walk into a scan every day... would be so reassuring.

Remember you have been taking loads of drugs, plus a shed load of aspirin - and so all the rules about bleeding and discharge and pregnancy in general don't apply to us!

Just as the meds mask nausea etc. god knows what other stuff they mess with, like the CM...

Thanks for your timing advice on the meds Harriet, sounds like you have it nailed.
Sorry you are going through this uncertainty with discoloured CM. Are you still cramping? Yes you must try and get to epu tomorrow just to put your mind at rest x

I've got a scan tomorrow. Really fearing the worst now but just have to wait and see.