Immune /natural killer cell treatment when ttc or pregnant (aka the 17th pred thread!)

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This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

Wow Trying! You read my mind! Just yesterday I tossed out a soup I was about to eat when I realized it wasn't BPA free. Have since been trying to find an alternative. Will look up your recommendation! Thanks!

I'm trying not to be too OTT so bought it without thinking re bpa but before heating it micro I checked and said it was free they have loads of flavours and as they gluten free too win win! I highly recommend this flavour yummy!

Also a fam friend of mine has been suffering with infertility and miscarriahes for 9 years. I don't know all the details but they haven't seen people privately and have struggled financially....

But finally they had a baby today!!!!!

Keep the faith girls :)

That's so inspiring! I wonder if they did anything differently towards the end...

Don't think so! They stayed here never saw anyone privately and just did rpt ivf cycles and kept trying naturally. Somehow it all fell into place :) not sure if it was ivf or natural cycle. But either way it worked!

That's such fantastic news about your friends Trying, just shows it can happen without the major interventions.

Loving your positivity Drttc... I'm trying to think that way too.

Don't think i really need to eat GFM just need to cut the carbs down I think. I need to lose a few lbs... . I've got a week off next week so I'm determined to get back into my exercise routine and might try low carb.

I'm cd12 at the moment, slight hint of a line on the opk this morning.... hope the pred hasn't put my cycle out.

Had a tarot reading last night - very interesting. Death card came up twice!! But apparently it means transformation/change. All my cards apparently indicate the end of one cycle and the beginning of a new. Also drew the baby and family cards...so positive thinking from me!!

Hey Seeking! How's the pup? And the house? Hehe good luck with your week off. It's really nice when you can take some time to treat yourself well. Snuggle up, eat yummy food, and plan something nice to look forward to if possible :) Enjoy DTD too!

Wow how interesting about the tarots! Tarots or not though, you'll get you're baby Seeking. So many things point to it happening!

The pup is great thank you Drttc, very naughty!! But he's so loveable!
House plans are finally coming together, we've just ordered our kitchen....eeekk! Got so much to do though!

i know I will get there, with or without the tarot reading. To be honest, I'm very sceptical of it all normally, but it was interesting.

Hehe sooo cute, Seeking! Have you started daydreaming about Christmas decorating? I know it's early but I can't wait! This year will be the first time we do up our own 'proper' home and I'm so excited :)

BFN for me today! Cycle 3 since my 4th miscarriage... Though with no CM all month and expensive ovulation tests not working properly- I could see it coming! I'm wondering if doing intralipids 2 days before ovulation messes with it? Dr S never specified when just 'before' ovulation. This cycle I may aim for a week before to try and minimize that influence... Seems like that's what IVF-ers do for theirs.

Trying, when did you have your pre-IVF intralipids?

Hey drttc
Sorry another bfn, but like we said rem it's about the sticky one!

Yep we have it a week before as the effects last about 3/4 weeks so all ready for embryo transfer and then just at bfp we go again.

How much co enzyme is everyone taking? X

Thanks, Trying!

Do you mean the ubiquinol? I take 200 (mg) a day!

So just found out intralipids can no longer be done at home. Only at their clinic in surrey, and price has gone up to £300 per session. So I'm supposed to take a day off to travel (and pay to go) to Surrey on top of paying £300... Before even being pregnant! This is just too far for me... I'm so disappointed :(

That's pants!! Why have they done that? is it just a mr s thing or has everyone stopped? Could u get ur prescription from somewhere else? Possibly Mr s will do them on a sat am?? So u don't have to take time from work
This whole journey is such a complex one-im sure it shouldn't be so hard!!

Ive just had info about pgd and it's got loads of risks and doesn't detect all issues....going to meet them on Monday for my scan to check im ok to start soon (if immune bloods are ok not back yet) and also to discuss pgd use in miscarriages

Ive got 6 pounds to loose in 3.5 weeks which if all goes well is when I will start...bringing bmi to 23.8..I hope I can make it happen! It's really quite hard and boring though!

I don't know where else I could get a prescription from? I hate to say it but why go from a cheaper option that can be done at home to a more expensive option that can only be offered at your one clinic in southern England? To make money... How is is this helpful to his patients around the country? I'm so upset by this I'm feeling like they are just draining us of every penny they can. I've wasted so much money on intralipids and also now they say it should have been done a week before ovulation.... Never made that clear to me! I could just cry. I had so much faith in this clinic. And now I feel like a desperate cash cow who is now poorer with nothing to show for it.

What risks does pgd have?

That weight loss sounds doable, Trying!

I've just called Dr Quenby's secretary and I'm thinking about switching to her. Have until I get a + ovulation test to decide (about 2 weeks) for her NK cell test this cycle. Though results take 4-5 weeks to come back. It costs £360 for the uterine biopsy (which she believes is different from NK cells in the blood). That's about what I'd spend visiting Dr S for 'follow ups' anyways... And she doesn't charge for every little thing! Her programme is pred and progesterone, and sometimes clexane (no intralipids). Big decision!

Well it doesn't find all the abnormalities, there's a chance u spend 3 grand and get no results, there's a slight chance of damaging the embryos and they will only do it if u have enough embryos on day 3. Then there's a choice of doing it on day 3 or 5-if 5 I think u have to freeze the embryos while I await results and then give it 2 months to restart again for a frozen transfer! But results more accurate.

Not sure how much more I can take either! But this was just the paperwork they sent I'll get proper info at my appt....

Hmmmm...that is v disappointing. I think he did that once before and sunny had same issue but the. It started up again at home? selondon gets hers from somewhere private maybe ask her?

Lots of people have sucess with quenby drttc. Only issue is if ur NK cells r normal u have to have faith u don't need pred and il and just take the clexane...I was too scared to do that as I wanted the pred!!! (Not that it helped !)) ivf clinics do it mr s way, but Quenby way is has reserch to back it up...

I have sometimes thought shall I just do an ivf cycle with none of the drugs and extras and see wot happens?! But I'm too scared! Maybe if this one doesn't work out, I might just do that (but please dear god let the next one work!)

Gosh Trying that sounds so bloody expensive for a leap of faith. From what I've seen about women who do pgd, it seems to work well as long as you can get those good quality embryos? How was that for you last time? So many difficult decisions with no real guidance on what's best for each couple. I'm so worked up right now and can only imagine you must be too with this decision looming over your head. Why :(?? Our journey is one thing, but add in making huge decisions with financial consequences on top of it.... F sucks!

You're a fountain of knowledge, Trying! Thanks. I suppose if she says I don't need steroids I could take them under Dr S in addition to her clexane? Another difference is she does steroids from the start of cycle not just from ovulation.... Which I may need?

I don't know what to do. Ask Dr S if I can have intralipids at home? Remove intralipids from my programme if he says 'no'? Or just switch to Dr Quenby?

It's so hard isn't it! I had this problem too when I did my last round of ivf-do it under Mr s or under my ivf consultant. Turned out management was similar so I just went with ivf chap...

I suppose getting an opinion from quenby is no harm but then it's another 360! And u can't TTC that cycle as they need to do a biopsy...(I think??)

I'm going to do what argc say I should they seem pretty on the ball. my consultant said it will remove one variable so it's worth trying. But did say it's not fool proof and there's many other reasons I could miscarry not related to that so obv it's not 100percent. Last time I got a good number of eggs, and good quality and they all went to day 5 (2 died on day 6 and were a bit dodgy).

Im going to let argc decide for me! my ivf consultant last time told me our cycle was was really good (everything went well and as expected ) except My lining was on a lower end but still within normal range. I said - thanks, a "good" cycle in ur eyes but I still have no baby :(

Absolutely exhausted from it all but can not stop chasing. I just hope it works out somewhere along the line

Hey ladies,

Its an absolute minefield. I'm really disappointed for you Drttc that he's stopped working with Healthcare at home entirely. It doesn't leave many options for people who just live too far away. And quite frankly I wouldn't want to sit in his office for a couple of hours while its done. It's boring. At least with health care at home you can sit watching your choice of crap tv.
I think if I were you i'd stick with DrS' plan. if your results come back with no NKu cells you won't get the pred, which you'd then go to Dr S for anyway. Maybe speak to him about taking pred pre-ov?? And def ask to have IL at home, its a bloody con!!!

Trying - i think i'd go the same route as you. Follow argc advice this time and then assess after if need be (which you wont have to). They really are amazing. Hard work but amazing. And you clearly had good results egg wise last time so hopefully their protocol will be the tweak and managament you need.

I'm 3dpo. Started pred today so I can take it longer and test later. Also started progesterone so will stop that after 10 days if no luck. Fingers crossed. We def need a little boost here...

I love christmas too Drttc - although this year I think our house could be a bit of a building site so may not put too much effort into decoration.

hey seeking, i feel like ur month has gone so fast while mine has dragged! i have everything crossed for u! glad ur cycle seems to behave. progesterone makes ur lining more selective doesn't it? hopefully it will reject the embryos which shouldn't land there! I'm still thinking this is part of my problem...obv now i don't easily get a bfp but theres a very obvious reason for this! but before it was so easy to get a bfp, and i got one on first ivf cycle too....i just wish i had chromosomal analysis as a missing part of the jigsaw....

ugh, i usd to love xmas but every year i hope for a baby and now xmas upsets me! its going to be the third this year with no baby :(
me an dh going to fly away somewhere exotic (with the money we will have post argc) if we nowhere closer! but glad u two still find joy in it! hopefully i will one day too!