Immune /natural killer cell treatment when ttc or pregnant (aka the 16th pred thread!)

[sunnyday01]

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

[Seekingmiracles]

It's just crap that even with all the treatment for immune issues, chromosomes can still fuck things up. But I suppose that's just the risk we have to take, it is really really bad luck. I still have faith in DrS and his treatment plan so hopefully next time we'll have more luck.

[Tryingno1]

Yes seeking.. As u said u got further this time...and hopefully that's testement that the meds r working.

I'm waiting my call to check some eggs fertilised-no call yet

Sasha welcome, I think determined on this thread had NK cells which didn't drop with intralipids and pred and she's working out what to do. Maybe she will be on to let u know her thoughts but if u scroll back she has commented on it. Not sure on Mr s thoughts on it sorry.

[Drttc]

So true, seeking. Such a scary situation when even most women without any issues will have a chromosomal loss if they have a few pregnancies. My mom had 5 children, 1 miscarriage (around 9 weeks). My mother in law had 3 children, 1 miscarriage (around 12 weeks). Absolutely soul destroying 'bad luck'. And how on earth are we supposed to know what's going on without being able to check? I wonder if in the future they'll be a chromosomal test before the 12 week mark. Sounds extreme but it would save a bit of pain.

I know that finding out my rubbish hcg levels early on has helped me accept the situation better & not get my hopes up. Still no pain or bleeding, which really would have excited me as I'm almost the furthest I've ever been.

Trying, fingers crossed for your eggies & can't wait to hear how they did! Such a cool process! Surely DH is still quite young as well, just because there's been a dip it shouldn't be permanent. I think you've both done really well to investigate this at this age & that has got to make success more likely. I always think, well even if it takes me years, I'll bloody get there!

[Tryingno1]

Drtcc so glad no spottng. I have everything crossed for u! R u doing ok?

So we have 6 embies. If we have more than 4 tmrw then transfer tuesday. Ow it will tmrw. So another call tmrw am! I hope they survive the night and are good quaility as rates of sucess r much better with a 5 day transfer...thanks for ur all wishes xxx

[Drttc]

Trying, omg 6 embies!! Eeeek! Did you mean you might transfer tomorrow (sorry didn't understand what you wrote) but prefer Tuesday transfer? Would you transfer 1 or 2 at a time?

I'm fine really! Don't feel pregnant, just completely normal & comfortable. I'd say I'm 80% acceptance, 20% holding out for a miracle. I'm also curious as to whether I'd make it to seeing ANYTHING on an ultrasound (as I never have). So sick of paying for every little thing though... Especially when it's bad news. 'You've miscarried- now PAY UP!'. We are way too poor to spending this amount of money :( Don't even know where we've managed to get it from!

[Tryingno1]

They ideally have better pregnancy rates from a day 5 transfer which is tueaday for me. But if they have less than 4 good qaulity ones tmrw they don't take the chance incase they all
Die ! So they pop them back in earlier (tmrw).
I'm really crossing everything that they all are good qaulity and we are set for Tuesday. Another nerve racking 24hrs! They ring tmrw at 8am as they can't tell the quaiity today!
Thanks for Listening. I know none of this doesn't mean anything u to guys!
The pred will be stopping ur symtpms and the fact that u have had no spottimg is def a good thing. Enjoy the sun and think happy. When is ur scan?

[Drttc]

Thanks Trying! I'm absolutely fascinated by the entire ivf process so feel free to keep sharing! Soon you're going to be officially PUPO (pregnant until proven otherwise). It's a thing ivf-ers say after transfer- cute! Hoping you get the 5 day transfer you're hoping for.

I've not arranged a scan so not sure what I'll do if I make it to Monday... Might try to get one at my local EPAY? Also have a GP appointment today where I want to ask for karyotyping & AMH testing. Hope they listen & agree instead of giving me the run around...

[Drttc]

Local EPAU*

[Snoopysimaginaryfriend]

trying I have all my digits crossed for you. Come on little embies!

sasha have you spoken to the doctors at the Lister about your concerns? Hopefully your appointment with Dr s will give you some options. Like drttc said it's awful enough to miscarriage but when you're paying hand over the fist for the privilege it's even more galling.

drttc my mum keeps telling me I have to be strong like my grandma. She had my mum then she had a little girl who died of leukaemia, a little boy who died of cot death, then she had my aunt and then she had a stillborn little one. This was all in rural spain. She had a breakdown after her son died but she had to keep going.

I hate that this journey has robbed us all of so much. I think back to happy I was the first time I got pregnant, my little honeymoon baby. I'm never going to have that again. I'm never going to be one of those women who have a 'happy surprise' because everything has to be planned and medicated and even if it wasn't the anxiety I feel when I'm pregnant now is awful.

It's my first due date tomorrow

I'm so sorry that we are all suffering so much. I just hope we are all strong enough to move forward and keep going together.

[Seekingmiracles]

Trying that really is fabulous news! I really hope they all get to blastocyst. How many will they put in? One or two?
I've had such a bloody nightmare trying to sort out an erpc. It's like the NHS has a meltdown when you mention private care. They don't know how to function! Finally managed to sort it myself by ringing the fBulous nurse at my local epu.

Im still hopeful for you Drttc....there has to be some good news to come on this thread. X

[Tryingno1]

Oh snoopy I'll be thinking of u tmrw. Are u going to do anything to mark the day? I know our happiness is totally Robbed and pregnancy is no longer a happy thing! It's really shit.
Yest as I was hysterically crying about DH sperm he reminded me neither Of us were dying! And we were healthy and its not that bad and we will just have to get stronger and fight through it together.
To be fair I replied saying, "I'm sick of being strong! I can't take any more hurdles" But then I suppose u just do?! I've booked dH a urology appt I hope he has some advice re freezing/soerm retrieval /why counts r nose diving. And one day I Hope To God I can look back at this nightmare with my baby and think how on earth did I make It!

[Drttc]

Ah Snoopy I know it's so depressing! I've decided to just bunker down & keep trying, while accepting that it's going to hurt. It's sounds unhealthy but detachment has enabled me to bounce back much more quickly than I use to. Of course every day is different, and sometimes you can't help but feel complete shit!

Seeking, thank you. I don't think I'll be a source of good news this time around. But I do honestly believe we'll all get there eventually!

The who due date thing has bothered me a little bit... Mainly seeing how real the pregnancy became for people who got pregnant at the same time. Ouch ouch ouch :( You just kinda look at them and think how blessed they are... No idea how hard it can be.

Trying, I find myself saying similar to DH! If we can't remind ourselves of everything we do have, the journey becomes much harder. A warm home, good food, and 'I love you' every morning is so much more than most people in this world we ever have.

Went to the GP and she was more interested on getting me an urgent scan. She rung several people & half said no while the rest didn't answer. She was annoyed because she said she's done it before with no issues. So she's referring me to the clinic that just ran all my NHS tests as the letter said they'd see me again when pregnant. She says to hold out for whenever they give me a scan. If I've lost it by then to continue with the appointment but go my DH to request testing for both of us as a couple (as she thinks it's very reasonable for us to get some). There was also discussion about ivf if we can find an issue. So, she was very supportive, but in terms of help/treatment I've left completely empty handed. Not even a booking for anything! Standard!

Looking forward to the weekend!!

[Tryingno1]

Seeking sorry it was such a mess trying to sort it out. Iike u need drama at a time like this. Hope ur holding out ok.

They only transfer one on an nhs cycle at my place. I'm happy with that as I know twins increases miscarriahe rates! I literally can't wait till 830 tmrw am to hear that hopefully they are all doing well and tuesday is on!

Drtcc glad Gp was helpful. Ur doing really well, keep focussed and postive and hopefully by end of next week u will hve some
More news xx

[Hula2]

Seeking - sorry on top of everything you ve had a hassle sorting out your erpc. Must be very hard waiting for that. It so shit that on top of immune issues we ve also still got the random back luck of a chromosomal mc. I think freelance girl who posted a little while back and was on the thread before managed to have two pred babies and had a chromosal mc in between them.

Trying - yay for 6 embies, sending lots of positive vibes for top grade ones.

Drttc - wow your poor grandma, she must have had incredible strength to get thru all that, sounds like you and your family are made of strong stuff. Hope you get your scan soon.

Snoopy thinking of u tomorrow.

[Snoopysimaginaryfriend]

trying isn't it surreal and amazing to think your little one could be doing its thing right now in a little dish. They should do something like embryocam so you can watch them growing.

Pregnant Until Proven Otherwise - I like that

seeking and drttc it's so rubbish that the one time you just need the system to be on your side and not add to your stress it can't manage it. Makes my blood boil.

I don't really know what to do tomorrow. I just feel a bit numb tonight. I took DH out to watch a film at the little cinema we went to for our first date. We talked about puppy names.

The forget me nots now have six shoots although one is definitely growing faster than the other.

[Tryingno1]

Morning girls. I have not slept well! Waiting anxiously for my call..poor dh has been up since 3! Yes snoopy I have the embryoscope it's meant to improve rates of preg and Yep I get a video link so I can see them grow! I don't want to watch it yet though!

Glad u went out for a distraction. Puppy sounds like a great idea I think u should do it! Hope ur ok today I'll be thinking of u.

Snoopy how r u today, thinking of u too. How is ur dh doing? Hope ur friends who knew are being helpful during this difficult time

Xx

[Seekingmiracles]

Not long to wait now Trying! Hope you get some good news.

We went to the cinema last night, saw the new Jurassic Park film. Needed a distraction from my own mind. I can't believe I'm going through all this again. How can one it be fair. We've been through so much already. Dh doesn't really talk, he bottles stuff up. He told his dad yesterday. I'm glad I did tell some friends I was pregnant - I don't think I'd have been able to just pretend everything was ok. It's my birthday next week and obviously not in the mood for any kind of celebration. That's 2 years on the trot I've had my birthday ruined by MC. Had my erpc the day after my 30th last year.

Drttc I hope you get a scan sorted soon. Sometimes the NHS are fab and at other times they don't know their arse from their armpit. Had to fight for chromosomal karotyping with consultant yesterday as she said that because 2 of my pregnancies weren't confirmed by scan technically I wasn't eligible. Blood boiling was an understatement. Thankfully because I was under consultant care for rmc I managed to fight and get it sorted. I could still have had it done privately and sent to the lab DrS uses but that's £365 and we've already spent so much. I'm still undecided though as his lab takes 3 weeks and the NHS could take 8+ weeks.

[Tryingno1]

Hi seeking.

miscarriages seem to plaugue my bday too. Miscarriage one on my holiday for 29th bday, 3 months laster number 2 and miscarriage 3 the week before my 30th. Needless to say crying and drinking copious amounts of wine to get through the day helped slightly numb the pain. I had taken a week off during my 30th thinking I would be like 11/12 weeks and want to stay at home but instead buggered of to siciliy with dh. This time it's my bday in 2 weeks and I'm not going to test early as I refuse to be in floods of tears again. I tell myself every bday will be different but sadly I'm in the same childless situation. It's so shit. I hate my bday now! My dh bottles things up too he does talk to his brother sometimes but ow he just keeps it in. Wondering if all the stress has affected his sperm but surely it can't nose dive so much with stress.

I'm so cross about the karotype test! I was thinking, whilst ive been tossing and turning I was thinking "I hope seeking gets this done" the nhs with its strict rules etc. I think the nhs is great the sometimes they refuse to bend for no reason other than the computer said so. Also make sure u tell them a million times on the day. They managed to put mine in the wrong pot once and they didn't send it off the second time to say I was fuming is an understatement. They don't do it that often so I think they were not used to the pots and paperwork.

Give a f if it wasn't on a scan?? What the hell does that have to do with anything? Surely they are doingg the d and c as there was something on a scan somewhere?!

Well done for going out yest. And glad u feel u can talk to ur friends. Have u taken some time of work. Thinking of u lots it's such a sad time.

[Tryingno1]

Ps we are both 31 days within Eachother. Let's hope our 32nd bdays and filled with some more happiness (ONCE AGAIN I say this)

[Seekingmiracles]

I would have been 12 weeks exactly this birthday... I really hope this time next year I'm actually looking forward to a nice birthday. What date is yours? Mines 24th.
DrS did warn me that the NHS are pretty unreliable with karotyping (losing it, late testing etc, it is a worry which I why I'm considering paying for his lab to do it.) it such a horrible thing think about on top of everything else.
I really hope this works out for you, I'm keeping everything I can crossed for you.
I'm manically googling ways to improve egg quality and dh sperm count- he had it in November which resulted in slightly lower than normal motility so googling that too. Going to go back to the Drs and get that re Tested.i feel better if I'm armed with a plan.

[Tryingno1]

Mine is 22nd. We are just going away locally to a nice hotel for the night (with no hpt!)

I'm the same I always need a plan. That makes me feel better....urs sounds very sensible although I'm sure boderline motility isn't anythingn to worry about. I have my dh on cocktail of meds but it's hasnt helped! His issue is obviously something which needs further Ix. It's why I was devastated when I found out the sperm was going down and we had to think about freezing. (I burst out crying infront of consultant after egg collection I think he thought I was mad!) My back up plan if this doesn't work was 10 rounds of Isci until one did!!!

Now I feel like we may not get that many as frozen sperm doesn't always defrost and what if next sample there is no sperm?? etc. Anyways that's another drama for me to deal with once I know the outcome Of this cycle.

Take it easy today. I'm goggle obssed and spent all day yest on it. I'm going to step away from it this weekend and try make sure dh keeps me busy!

Waiting patiently.....

[Tryingno1]

Ps when is ur puppy coming? I hope it brings u love and smiles :)

[Tryingno1]

Yay transfer on Tuesday!