Anyone taking part in the Response Medical Trial or any other medical trial?

[sizethree]

Hi, I'm taking part in the Response medical trial and wondering if anyone else on here is too?
It's been a very difficult year and a half and I have had three consecutive miscarriages, 1st in Nov 2013 at 12 weeks, 2nd in July 2014 at 7 weeks, 3rd in Nov 2014 at 9 weeks. It's a 4 month waiting list for my Recurrent Miscarriage Clinic so I'm taking part in the trial as want to keep things moving as worried I'm running out of time (I'm 36 this year - although I was 33 when first started TTC) but I'm in the 2WW and feeling terrified.
There's a lot of extra support offered as part of the trial but I'm feeling a bit lonely and out on a limb about it.
Anyone else on the same boat or had medical trial experience?

Well mine showed 3 days past smiley tbh! I think the smiley showed late, but my tests started to show a line then, strange! Proper quick line 9dp smiley.

Sickness ok thanks, still lingering but not as bad. Eaten loads of mint imperials tonight and has seemed to help!! It's mainly afternoons and evening it kicks in, bleugh!

you had a positive 3 dpo?
glad sickness is bareable your nearly 7 weeks now x

Hi ladies. Hope you're both having loveky weekends.
I was away up in Loch Lomond for an escape with DH. Much needed and I feel a bit calmer now.
Just got to get through 3 days at work before the scan.
Still no real symptons have kicked in but I am very tired and although no sickness, I haven't been that fussed about food today, and I'm usually a big greedy guys. So hoping that is a good sign. And I suppose that lack of period is still a symptom.
My comment he other day was that I won't get any reassurance from doing another pregnancy test and seeking a darker line, as sadly the darkest line ivd ever seen on one of my tests was post MC. Where there must have still been tons of HCG in my system. I was asked to test by the Response trial manger before I went in for my initial appointment. As I needed to be HCG free/ ovulating to be enrolled properly.
It really shook me so I'm staying away from them, as tempted as I am to try anything to reassure me.
Plus, I kind of miss peeking on sticks as it seems I've spend most of recent months doing that!
Claire I got my very very faint BFP 10 DPO. And I got it confirmed and the trial injections allocated 12 DPO.
They want to catch you asap as you'll know, the drug is supposed to help with implantation issues.
Choccy are you convinced you are on the drug? I'm pretty flippin sure you are!
I think I'm on the placebo. Which I suppose means I'm no wirse off than if I wasn't on the trial at all. And the extra scans will show up any issues much earlier than before, which offers some comfort.
The thing that has haunted me abut the past two MCs was that things really went wrong weeks before I had any clue about it.
Choccy do you go in this tues for an appointment too? I think I remember then telling me that get skip week 7 for some reason. (Either that or my trial manger is off on hills that week!) fingers crossed I get that far.
Very much needing both your positive vibes this week to get me through. X

I was hoping you were ok sizethree so it's lovely to hear from you. hope you had a relaxing weekend, you definitely needed it. I see what you mean about not getting any reassurance from doing a test. I was the same the hcg hangs around & I never knew until weeks later that it had gone wrong. the main and most Important symptom is the lack of period, your still early days for symptoms that's if you even get any......why do you think you have the placebo? I hope you both have real drug, I really do.
I'm not going to say relax and dont think about it as I know for a fact I will be the same, but I guess you just need try and be positive and have faith that it will work out. it's so hard I know. not too long now until Thursday, then you may feel a bit better. thinking of you and sending you as much positivity as I can.....you can do this xx

If you go further up thread Claire, my tests are somewhere if you can be bothered to look lol! Was strange, I just had the urge to test as I was sure I ovd earlier as I'd always done!

Oooo that sounds a lovely weekend sizethree, glad you got away from it all. Your scan will be here before you know it sweetie :) Sending you tons of positive vibes!! Did you ever have a scan before?

I'm convinced I'm on the drug yes. I just find it a strange coincidence that I've lot so many so early and started this and this is where I am now!

Sorry pressed post!
Dh said he overheard the MW after the scan that made him think they know what I'm on. Something like 'it's worked' or something simple like that, he can't remember. I said they didn't but he thinks that's why I was there so long at my first appt, they were trying to get me the drug. I've told him its blind and NOONE knows, but he said he's sure I'm on it too.
No appt for me this week, next one is 8 week scan a week Tuesday :)

opks pick up pregnancy so that might be why choccywoccydodah...eek how good is that for you.x

I don't think it was that, I was only cd18 when I got my smiley, but in 16 months before I'd ALWAYS got a + opk stick at cd14, then it disappeared by the next day (bar one month was cd15). So I was 3 do smiley or 7dp when I thought I ovd :)

Thank you bith fur your kind words and encouragement.
Choccy, yes I've had several scans.
2 with the 1st pregnancy. One at 7 weeks, with a big strong flickery heartbeat, then one at 12 weeks where baby was confirmed dead. 2nd pregnancy, one at 7.5 weeks and heartbeat seen but meandering small and then MC'd within next 48 hours. 3rd a scan at 9 weeks which confirmed baby had not developed properly and died. I've also had the chance formation scans a week after each of the three MCs to check there's no orwgnancy remains. So I'm understandably not good with scans. They properly give me the fear.
I just don't 'feel' like I'm on the drug. I've been oregnant three times previously and this during feel any different.
And genuinely my luck is awful that with a 50/50 chance, I'd always get the bum deal!
But there's still a change if sucessful lregnancy without the drug, so I'm clinging ti that. And finding out if there's a problem sooner rather than later will be a sad relief.

Its awful that you had positive scans and still went on to mc. Doesn't give us much peace of mind then does it :(
Don't think about if you're on the drug or not, it's 50/50 like you say, so you've as much chance you're on it as you have not.
Re your symptoms, I'm over on the October AN thread, and a lady who had a mmc on there had a scan at 5+5 all ok but she's had no symptoms whatsoever! She's just had another scan just over 9 weeks and all is still fine.
There is hope sweetheart, you've just got to believe in yourself, and your lovely baby you're carrying :)
Not long til Thursday xx

Thanks Choccy. I'm sorry to be such a misery guts and really don't want to soil the positivity. It's just that I've been heartbroken so many times before that I'm trying to harden myself to the upset.
Just wanting Thursday to come so I'm not in this awful limbo of not knowing either way.
That's loveky news about the lady in the thread. It's good to hear stiries of hope.
How are you feeling? Hope this fury night flies by. I wonder if it'll feel weird for you not going for an appointment tomorrow?
How are you Claire? How many DPO are you? Is it 3 now? C

'C' was supposed to be an 'X'

I can understand feeling the way you do sizethree its a self protection thing. are you 6 weeks on Thursday?
are you 7 weeks today choccywoccydodah? I'm 4 dpo x

I know exactly how you're feeling sizethree. I'm sure once Thursday comes you'll feel so much better :)
You're not being a misery guts, it's natural to be how you are! You're not bleeding so that's a positive sign!! Not long to go now :)

I would so rather have no symptoms!! Felt sick all night last night and it kept me awake, and my boobs were hurting. Had a stuffy nose so had to breathe through my mouth and now have a sore throat :(
You're welcome to it!!
Meeting a friend in Costa today for lunch, haven't told her yet but she may know as she works in the hospital gynae and c sections, and she knows the staff from my trial. Will tell her anyway. May need to sooner than later as the smell of coffee may send me over the edge! And I love my coffee usually.

Yes 7 weeks today Claire eek!
Not long til test day for you

7 weeks is brilliant choccywoccydodah so pleased for you.
only today and tomorrow sizethree.

I feel like this month is not going to be my month but guess you never know x

Thanks you lovely two.
I'm not sleeping well at the moment so I'm sure that doesn't help with anxiety.
Heading home on my lunchbreak for a nap as I'm exhausted (lucky the studio is close to home!)
Congrats on 7 weeks, that's a great milestone Choccy.
Claire you'll be POAS in no time. It didn't feel like my month either. Funny how you can never ever tell when that BFP will show itself.

Not sleeping and exhaustion are great 'signs' sizethree

morning ladies how you both feeling?

sizethree only one more sleep hope your scanxiety isn't too bad . thinking of you x

Thanks Claire. Just got to get through today and have s relaxing evening.
I think my boobs grew overnight so hoping that is a sign for reassurance.
Busy day at work today to keep my mind off things.
My appointment is at 8am tomorrow so it's good to get it over and done with without having to hang around half the day first. I'd get nothing done.
I've made abolition no plans beyond the scan tomorrow. Hoping scanxiety stays under control.

Ahh boobs growing is a wonderful sign!!

thank goodness your scan is 8am that's brilliant as nothing worse than late appointments xx

Afternoon Claire n Dolly

When you testing Claire?

Great sign sizethree, not long now!! So excited for you!!

All good here. Was full of cold yesterday and sicky all bloody day, but today it's nearly gone! Still stuffy nose, but nausea not too bad today. Still there, still no appetite, but really mild. Hopefully this is the end of it!!
Boiled sweets are amazing!!

glad your sickness is more bareable choccy let's hope the worst is over for you.

I'm going to test Fri (pos ov was last thurs) but prob didn't ovulate til Fri? what the tests like ive not looked?x

Oh and why dolly?x

Dolly Parton numpty
Roll on Friday then!!
Tests are ok, I got faibt lines on them first but any line is a line!
I never showed on IC dip sticks

lol Im being very blonde today!!x