TTC or pregnancy on prednisolone or similar part 12

[teamdozie]

This is a positive thread for all those diagnosed with High or Very High NK Cells and looking to start TTC or already pregnant on Prednisolone and/or Intralipid treatment.

Newcomers very much welcome!

Team that is bloody brilliant news!!

So great to see the list of success stories posted above, thanks free - it's heartening to see how many babies there have been!

Tested and retested over the weekend and got a BFN - not even the ghost of a line on the strip though I squinted as hard as I could So that means that I'll be starting on SO cycle number 3. Will be going to Epsom to have the cyst in my right ovary drained on Friday and maybe that will produce a better ovarian response next time. Not losing hope yet! Onwards and upwards!

Waves to everyone xx

Team absolutely fabulous news you have made my day!! It is so amazing when you expect the worse.

Delta Thanks for your kind message. It’s great to know that there are real women out there that have been through these traumas and come out the other end successfully. I am holding onto these positive stories and reminding myself that I could be one of them.

Village I know you were worried that cyst might be hampering things so although not nice, getting rid of the little bugger might boost the SO effectiveness. Please please do not loose your faith - there are so many good stories knocking around here and in the media at the moment and we just have to believe in ourselves. I know that something good will come our way!! Big hugs

Hi all

team so relieved for you! I was going to say that I had 3 massive red bleeds at 5+4 and it turned out I was expecting twins, but lost one, but dd was a keeper!
luna so sad for you, things are just so unfair. I think I only had one of mine tested, and it didn't show anything.

baking congratulations on team pink!
village hopefully getting rid of that cyst will help!

First post-m/c AF this weekend. Spoke to clinic in Spain (It's DE ICSI) and sent over bloods. Still chasing the results of my mamogram - hospital say they've faxed them, drs say they haven't received them. Aagh! Once all that's sorted I should be good to go after next AF..

Thanks Luna and Remember. I've always conceived naturally within about three cycles (except for DD, who took 5 and it felt like an eternity!) so was hoping for miracles from SO, but so far nada! Just have to keep trying.

Wonderful news, Team!
Here's a link about the beneficial effect of melatonin on egg quality, for anyone who's interested. I've ordered mine from Vitasunn; surprisingly cheap. The effects seem to be quite powerful and also quite fast. For instance the rate of good quality embryos more than doubled when 9 IVF patients took it compared with their previous cycles. As 80% of eggs are meant to be abnormal in your forties, that's got to be worth a go. Luna - something to try alongside the SO? I wonder what Mr S thinks of it?
www.ovarianresearch.com/content/5/1/5

team I am so relieved! I was worried about you all day.

I should add that although this study and other studies show it to be safe, I have found sites listing drug interactions which it would be wise to check out before trying it. One of them lists as a potential side effect disruption of ovulation!

Village , Luna , Baking, Brown and Remember thank you so much for your support!

It's a long journey ahead and I know it won't be over till the little baby cries!! And then that's just the start! Lol!

Remember I've experienced that before several times but I knew this time it's only the one!

Xxxx

Hello Everyone,
I've been finding it really hard to think about being pregnant, so over the past week and a bit became totally avoidant of anything to do with pregnancy, almost as if it would jinx me. But I missed my friends on here. Glad I have popped back as reading the last week's threads is cheering.

Luna you have been through so much and still send positive and lovely messages to us pregnant ladies. Thank you. It's really special and means a lot. That Daily Fail article was tough. I can't imagine going on and on after 20 miscarriages but we are all different and everyone will have a different threshold for stopping. You're right, it is much harder for men to understand. Do take your time with decisions. My hope for you is that you get some starry RL support to equal that you give to others on here.

Team what a scary rollercoaster for you, but good news. I was holding my breath reading and can imagine what you've been through.

Baking Pink, hurrah and lovely that all is going well.

Brown very interesting about Melatonin. My understanding is that it only suppresses ovulation at high doses. Everything I've read seems to suggest that 3mg per day or lower won't interfere with ovulation.

Free great to see you back. Thank you for posting the baby list. It's long and so inspiring. You're right, I do think that it is hard to keep posting when there is good news but what a reminder that it is important to do.

Village so sorry about the BFNs. I wish you lots of luck and a pain free cyst drainage on Friday.

My news is that the chicken pox have finally left this house, hurrah and I am still having all day morning sickness. Finally overcame my maternity bra phobia and bought some Hot Milk Lingerie off ebay. Vair Naice. And good not walking round in my too-tight underwired feeling as if I'm having an all-day mammogram. Breathing is better too.

Going for ten week scan this afternoon. They had forgotten to book me in for a scan so I have been squeezed into the 'high risk teenagers' antenatal clinic. I'm 39.

Waves to all, especially the new people I haven't met yet.

Good luck MrsP do you have a suitably teenage outfit for the occasion?

Thanks for the info Brown the Melatonin looks really interesting. The only worry I have is that I am never sure what can and can't be mixed with what and when best to take things. The doctors never seem to provide this sort of information and what I know I have learnt from the women on this thread. What quantity have you ordered?

I really appreciate your kind words MrsPixie and believe me, I have absolutely considered curling up in bed and not moving but that would not help me and my DH achieve our dream of a family. Alternative is positivity and determination which I still have (most of the time) and it is spurred on by the amazing stories of success that are posted on here. It's what keeps fanning the flames of hope and helps me know that we stand just as much chance of success as other lucky ladies on this thread.

I love the mental image of you sat with all the teenagers and am with Baking in that you need to dress appropriately and get down wit da youff!! Good luck xx

Team remember the mantra 'Today you are pregnant' and take it a day at a time. Calm and serene, breathe in and breathe out

Waves to you all xx

Mrs P I hope you gave yourself a Paris Hilton-style combover and wore lashings of mascara, teamed with a 'fierce' t-shirt from Superdry

Luna, I was told by Penny at Serum to take 3mg of melatonin, 5mg of folic acid (which is loads more than is in a general multi), and carry on with DHEA, so we can safely assume they are all fine together. She also knew from my notes that I was taking agnus castus, coenzyme q10 600mg and l-arginine so, again, all fine together one assumes. I should have asked her what she thinks of hydroxy while I was on the phone ...

Thanks for the info Brown. When I started with Mr S in October, of all the meds he assigned as part of my protocol, he never mention L'Arginine or Co-Q10 which I started taking following the Mumsnet thread advice. Have debated DHEA as well and might have the blood test just to get some more answers. The reason for the concern is that I am following the SO programme so have to take Letrozole which I learnt (just in time) did not go well with Agnus Castus and also learnt to take Hydroxy in evening and Omeprozole in morning as the two didn't react well together.
It is such a mine field and I am conscious of how ignorant I am when it comes to what I should be on and when to take it and what reacts with it.
My meds list at the moment is: Pregnacare folic acid; omega 3; vit D; 20mg Pred (am tapering off slowly every 4 days); Omeprazole (also tapering off); 600mg CO-Q10; 500mg L'Argernine and Hydroxy
it.
Is there a website that can help me to better understand potential conflicts between the things I'm on and would like to start as the Melatonin def sounds like a positive addition to my 'Collection' and could also help me with the Pred insomnia.

Apologies for the me me me post - it’s all a learning curve and I look forward to one day being able to advise others as the women on here have guided me

I agree, I am also very wary of self medicating unless advised by a doctor. brown at least penny has been through your notes and has given you the ok but I don't know if everyone should blindly take melatonin. There might be contra indications to some people depending on their circumstance that could make TTC worse.

luna I don't know of any website that talks about the conflicts between the supplements apart from info on agates pages. The trouble is different consultants prescribe different things so I would ask your own consultant on the supplements. I asked mr s about dhea and co q 10 and he was happy for me to take them. I've stopped the dhea now though.

I agree, Sue, and also on one hand I'm disappointed that I recently made an effort to reduce the number of things I am taking, it seems now that the way forward is to add even more. But on the other hand that's instead of all the drugs I would have taken for IVF. If you read that article, it really does seem one of the most promising new treatments - they talk of it as a possible 'cure' for infertility.
I would suggest having a consultation with Penny too, as consultations are free and simply involve filling in a form. Plus if I were still seeing Mr S, I would certainly tell him of the list of stuff I'm taking and ask his opinion.
I will email Penny and ask whether melatonin has any risks/interactions while I'm asking about hydroxy.

back from the teenage clinic, where I was mistaken for someone's mum. Scan good, saw kicks and waves and they dated me 10 + 6, which is ahead of my dates by five days.

Had a good giggle at your suggestions Village, Luna and Baking. Did I get down with da youf? I wore my jeans (gap maternity), silver converse, a very boring blue top and a Boden cardigan, which doesn't button shut over the enormous cleavage. DH has stopped talking to my face.

Luna what a lovely post. I can totally understand you wanting to curl up in bed sometimes but really admire your determination. My journey to DD was long and eventful. You have an amazing attitude and you will be a mum.

Brilliant, Mrs Pixie! And I hope you expressed your disgust at being mistaken for someone's mum, as you are clearly only 19!

Sorry Luna, I now realise I actually meant Village a few posts back when I was suggesting the melatonin along with SO, but I'm glad you also found it of interest.

Brilliant scan outcome Mrs P! And in fact you are someone's mum, he/she just hasn't arrived yet

Thanks for thinking of me re the melatonin Brown. Have read that you shouldn't take it for more than three months at a time; worth checking with Penny?

Hello to everyone. Sorry for brief post but laptop packed up this evening and am confined to a little diddy tablet which makes writing almost impossible!

Great news MrsP glad you showed the yoof how it's done. Next stop 12 week scan?

MrsP what brilliant news! And you are one week closer! Lol!

Village I hope Friday goes smoothly and then fingers crossed that then next month will be your month!

Luna you have amazing strength and determination! And thank you so much for your support!
How have you been feeling? I bet your DH and yourself have batted the what if ball around loads!

Waves to everyone
Xxx

Tum how are you doing?

Thanks for your message Team but I don't think I'm any stronger or more determined than others on this (and previous threads). I honestly think each one of us here is a lot more emotionally stronger than we give ourselves credit for - whether we are battling to stay calm in the early stages of a pregnancy; trying to remain positive through treatment; or recovering and planning our next steps after a mc. It would always be so easy to 'give up' and yet time and again I read posts that are awe inspiring and highlight our spirit to succeed.

My DH and I have had numerous heated discussions, and have agreed that we will try Mr S's treatment protocol again. Seems crazy not to after we searched for the causes of the mcs for so long. So we will definitely be trying again, but I have also made it clear that I can't keep trying to 18/20 mcs either. I've asked him to attend an info evening on adoption with me as neither of us knows anything about it and it could be the next step in our journey. Think it’s a way for us to feel that we have a tiny bit of control and decision making power in the process of us achieving our family. That is not to say that I am giving up on the idea of having a biological child, but it helps me to know that not all doors are shut.

Hello, just catching up on the last few days.
team what a horrid scare you've had and thank god everything is fine! So pleased for you!

mrspixie so glad your scan went well, sorry you were hemmed in with the youth but your post made me laugh.

Hi everyone else!

I had a scan today and thankfully heartbeat also found at 6w1d, next scan is next Tuesday.
Randomly the consultant I saw has also said I should go on clexane too, even though my thrombolias tested negative. He said with my history of migraine with aura, the odd haematoma, v-veins etc he thinks it can't hurt. Anyone else been prescribed this without a positive result on the thromby test?